Abstract
A novel dinuclear, distorted octahedral complex of nalidixic acid (nal) with Cd(II) metal ion with the formula [Cd2(Nal)2(Phen)2(Cl)2] has been synthesized in the presence of N-containing heterocyclic ligand, 1,10-phenanthroline (phen). The synthesized metal complex was characterized using CHN analysis, Fourier transformed infra-red, thermo gravimetric analysis, differential scanning chalorimetry, nuclear magnetic resonance, ultra violet-visible and single-crystal X-ray diffraction. The newly synthesized complex shows more pronounced antifungal activity compared with the parent quinolone against four fungi, namely Pythium aphanidermatum, Sclerotinia rolfsii, Rhizoctonia solani and Rhizoctonia bataticola.
The authors acknowledge National Centre of Integrative Pest Management, PUSA, India, for the screening of the drugs and Department of Chemistry, University of Delhi for providing necessary facilities.