Pushing the Frontiers in the Fight Against Antimicrobial Resistance: The Potential of Fecal and Maggot Therapies

Figures & data

Table 1. An overview of the benefits and drawbacks associated with FMT and MDT.

Therapy	Pros	Cons
Fecal microbiota transplantation	1. Effectiveness in recurrent C. difficile Infections 2. Potential in other gut disorders 3. Personalized treatment options 4. Potential metabolic benefits 5. Potential in modulating immune responses 6. Lower antibiotic usage 7. enhancing gut flora diversity	1. Limited understanding of long-term effects 2. Potential transmission of undetected pathogens 3. Variability in donor stool quality 4. Lack of standardized protocols 5. Ethical considerations 6. Potential unwanted weight gain or metabolic changes 7. Risk of exacerbating existing conditions 8. Public perception and acceptance
Maggot Debridement Therapy	1. Proven efficacy in wound healing 2. Natural debridement mechanism 3. Anti-bacterial properties 4. Stimulation of wound healing factors 5. Reduced healing time 6. Limited side effects 7. Applicability to various wound types	1. Patient acceptance 2. Limited application 3. Potential allergic reactions 4. Aesthetic concerns 5. Requirement of specialized training 6. Inconsistent availability 7. Risk of secondary infection 8. Lack of standardized protocols