755
Views
92
CrossRef citations to date
0
Altmetric
Miscellany

The role of the perirhinal cortex and hippocampus in learning, memory, and perception

Pages 246-268 | Published online: 13 Oct 2011

References

References

  • Aggleton , JP and Brown , MW . this issue . Contrasting hippocampal, perirhinal cortex function using imme-diate early gene imaging . Quarterly Journal of Experimental Psychology , 58B : 218 – 233 .
  • Aggleton , JP , McMackin , D , Carpenter , K , Hornak , J , Kapur , N Halpin , S . 2000 . Differential cognitive effects of colloid cysts in the third ventricle that spare or compromise the fornix . Brain , 123 : 800 – 815 .
  • Amaral , DG , Insausti , R and Cowan , WM . 1987 . The entorhinal cortex of the monkey. I. Cytoarchitectonic organization . The Journal of Comparative Neurology , 230 : 465 – 496 .
  • Angeli , SJ , Murray , EA and Mishkin , M . 1993 . Hippocampectomized monkeys can remember one place but not two . Neuropsychologia , 31 : 1021 – 1030 .
  • Arnold , SE , Hyman , BT and Van Hoesen , GW . 1994 . Neuropathologic changes of the temporal pole in Alzheimer's disease and Pick's disease . Archives of Neurology , 51 : 145 – 150 .
  • Beason-Held , LL , Rosene , DL , Killiany , RJ and Moss , MB . 1999 . Hippocampal formation lesions produce memory impairment in the rhesus monkey . Hippocampus , 9 : 562 – 574 .
  • Braak , H and Braak , E . 1985 . On areas of transition between entorhinal allocortex and temporal ioscortex in the human brain: Normal morphology and lamina-specific pathology in Alzheimer's disease . Acta Neuropathologica , 68 : 325 – 332 .
  • Brasted , PJ , Bussey , TJ , Murray , EA and Wise , SP . 2003 . Role of the hippocampal system in associative learning beyond the spatial domain . Brain , 126 : 1202 – 1223 .
  • Buckley , MJ and Gaffan , D . 1997 . Impairment of visual object-discrimination learning after perirhinal cortex ablation . Behavioral Neuroscience , 111 : 467 – 475 .
  • Buckley , MJ and Gaffan , D . 1998a . Learning and transfer of object-reward associations and the role of the perirhinal cortex . Behavioral Neuroscience , 112 : 15 – 23 .
  • Buckley , MJ and Gaffan , D . 1998c . Perirhinal cortex ablation impairs configural learning and paired-associate learning equally . Neuropsychologia , 36 : 535 – 546 .
  • Buckley , MJ and Gaffan , D . 1998b . Perirhinal cortex ablation impairs visual object identification . Journal of Neuroscience , 18 : 2268 – 2275 .
  • Buckley MJ Gaffan D 2000 The hippocampus, perirhinal cortex and memory in the monkey In J. J. Bolhuis (Ed.) Brain, perception, memory: Advances in cognitive neuroscience 279 298 New York Oxford University Press
  • Buckley , MJ , Booth , MCA , Rolls , ET and Gaffan , D . 1998 . Selective visual-perceptual deficits following perirhinal cortex ablation in the macaque . Society for Neuroscience Abstracts , 24 (14.6) : 18
  • Buckley , MJ , Booth , MCA , Rolls , ET and Gaffan , D . 2001 . Selective perceptual impairments after perirhi-nal cortex ablation . Journal of Neuroscience , 21 : 9824 – 9836 .
  • Buckley , MJ , Charles , DP , Browning , PGF and Gaffan , D . 2004a . Learning and retrieval of concurrently presented spatial discrimination tasks: Role of the fornix . Behavioral Neuroscience , 118 : 138 – 149 .
  • Buckley , MJ , Gaffan , D and Murray , EA . 1997 . Functional double dissociation between two inferior temporal cortical areas: Perirhinal cortex versus middle temporal gyrus . Journal of Neurophysiology , 77 : 587 – 598 .
  • Buckley MJ Williams H Hornak J 2004b Material-specific hemispheric asymmetries in visual recognition memory observed in normal controls are absent in epilepsy patients with unilateral medial temporal lobe excissions: Evidence for functional reorganization Society for Neuroscience Abstracts (200.10).
  • Buffalo , EA , Ramus , SJ , Clark , RE , Teng , E , Squire , LR and Zola , SM . 1999 . Dissociation between the effects of damage to perirhinal cortex and area TE . Learning and Memory , 6 : 572 – 599 .
  • Buffalo , EA , Ramus , SJ , Squire , LR and Zola , SM . 2000 . Perception and recognition memory in monkeys following lesions of area TE and perirhinal cortex . Learning and Memory , 7 : 375 – 382 .
  • Buffalo , EA , Reber , PJ and Squire , LR . 1998a . The human perirhinal cortex and recognition memory . Hippocampus , 8 : 330 – 339 .
  • Buffalo , EA , Stefanacci , L , Squire , LR and Zola , SM . 1998b . A reexamination of the concurrent dis-crimination learning task: The importance of anterior inferotemporal cortex, area TE . Behavioral Neuroscience , 112 : 3 – 14 .
  • Bussey , TJ , Saksida , LM and Murray , EA . 2002 . Perirhinal cortex resolves feature ambiguity in complex visual discriminations . European Journal of Neuroscience , 15 : 365 – 374 .
  • Bussey , TJ , Saksida , LM and Murray , EA . 2003 . Impairments in visual discrimination after perirhinal cortex lesions: Testing ‘declarative’ vs. ‘perceptual-mnemonic’ views of perirhinal cortex function . European Journal of Neuroscience , 17 : 649 – 660 .
  • Bussey , TJ , Saksida , LM and Murray , EA . this issue . The perceptual-mnemonic/feature conjuction model of perirhinal cortex function . Quarterly Journal of Experimental Psychology , 58B : 269 – 282 .
  • Charles , DP , Gaffan , D and Buckley , MJ . 2004 . Impaired recency judgements and intact novelty judgements following fornix transection in monkeys . Journal of Neuroscience , 28 : 2037 – 2044 .
  • Cirillo , RA , Horel , JA and George , PJ . 1989 . Lesions of the anterior temporal stem and the performance of delayed match-to-sample and visual discriminations in monkeys . Behavioural Brain Research , 34 : 55 – 69 .
  • Corkin , S . 2002 . What's new with the amnesic patient H.M.? . Nature Reviews Neuroscience , 3 : 153 – 160 .
  • Correll , RE and Scoville , WB . 1965a . Effects of medial temporal lesions on visual discrimination performance . Journal of Comparative and Physiological Psychology , 60 : 175 – 181 .
  • Correll , RE and Scoville , WB . 1965b . Performance of delayed match following lesions of medial temporal lobe structures . Journal of Comparative and Physiological Psychology , 60 : 360 – 367 .
  • Correll , RE and Scoville , WB . 1967 . Significance of delay in the performance of monkeys with medial tempo-ral lobe resections . Experimental Brain Research , 4 : 86 – 96 .
  • Dore , FY , Thornton , JA , White , NM and Murray , EA . 1998 . Selective hippocampal lesions yield nonspatial memory impairments in rhesus monkeys . Hippocampus , 8 : 323 – 329 .
  • Eacott , MJ and Gaffan , EA . this issue . The roles of the perirhinal cortex, postrhinal cortex, the fornix in memory for objects, contexts, and events in the fat . Quarterly Journal of Experimental Psychology , 58B : 202 – 217 .
  • Eacott , MJ , Gaffan , D and Murray , EA . 1994 . Preserved recognition memory for small sets, and impaired stim-ulus identification for large sets, following rhinal cortex ablations in monkeys . European Journal of Neuroscience , 6 : 1466 – 1478 .
  • Easton , A , Ridley , RM , Baker , HF and Gaffan , D . 2002 . Unilateral lesions of the cholinergic basal forebrain and fornix in one hemisphere and inferior temporal cortex in the opposite hemisphere produce severe learning impairments in rhesus monkeys . Cerebral Cortex , 12 : 729 – 736 .
  • Gaffan , D . 1974 . Recognition impaired and association intact in the memory of monkeys after transection of the fornix . Journal of Comparative and Physiological Psychology , 86 : 1100 – 1109 .
  • Gaffan , D . 1992 . Amnesia for complex naturalistic scenes and for objects following fornix transection in the rhesus-monkey . European Journal of Neuroscience , 4 : 381 – 388 .
  • Gaffan , D . 1994a . Dissociated effects of perirhinal cortex ablation, fornix transection and amygdalectomy: Evidence for multiple memory systems in the primate temporal lobe . Experimental Brain Research , 99 : 411 – 422 .
  • Gaffan , D . 1994b . Scene-specific memory for objects: A model of episodic memory impairment in monkeys with fornix transection . Journal of Cognitive Neuroscience , 6 : 305 – 320 .
  • Gaffan , D . 1996 . Memory, action and the corpus striatum: Current developments in the memory-habit distinction . Seminars in the Neurosciences , 8 : 33 – 38 .
  • Gaffan , D and Harrison , S . 1989 . Place memory and scene memory: Effects of fornix transection in the monkey . Experimental Brain Research , 74 : 202 – 212 .
  • Gaffan , D , Harrison , S and Gaffan , EA . 1986 . Visual identification following inferotemporal ablation in the monkey . Quarterly Journal of Experimental Psychology , 38B : 5 – 30 .
  • Gaffan , D and Lim , C . 1991 . Hippocampus and the blood supply to TE: Parahippocampal pial section impairs visual discrimination learning in monkeys . Experimental Brain Research , 87 : 227 – 231 .
  • Gaffan , D and Murray , EA . 1992 . Monkeys (Macaca-Fascicularis) with rhinal cortex ablations succeed in object discrimination-learning despite 24-hr intertrial intervals and fail at matching to sample despite double sample presentations . Behavioral Neuroscience , 106 : 30 – 38 .
  • Gaffan , D , Parker , A and Easton , A . 2001 . Dense amnesia in the monkey after transection of fornix, amygdala and anterior temporal stem . Neuropsychologia , 39 : 51 – 70 .
  • Graham KS Lee ACH Buckley MJ Spiers HJ Scahill V Gaffan D et al. 2004 Object and spatial perception deficits following medial temporal lobe lesions Society for Neuroscience Abstracts (201.9).
  • Hampton , RR . this issue . Monkey perirhinal cortex is critical for visual memory, but not for visual perception: Re-examination of the behavioural evidence from monkeys . Quarterly Journal of Experimental Psychology , 58B : 283 – 299 .
  • Hampton , RR and Murray , EA . 2002 . Learning of discriminations is impaired, but generalization to altered views is intact, in monkeys (Macaca mulatta) with perirhinal cortex removal . Behavioral Neuroscience , 116 : 363 – 377 .
  • Holmes , EJ and Gross , CG . 1984 . Effects of inferior temporal lesions on discrimination of stimuli differing in orientation . Journal of Neuroscience , 4 : 3063 – 3068 .
  • Horel , JA . 1978 . The neuroanatomy of amnesia: A critique of the hippocampal memory hypothesis . Brain , 101 : 403 – 445 .
  • Horel , JA and Misantone , LJ . 1976 . Visual discrimination impaired by cutting temporal lobe connections . Science , 193 : 336 – 338 .
  • Insausti , R , Amaral , DG and Cowan , WM . 1987 . The entorhinal cortex of the monkey. II. Cortical afferents . The Journal of Comparative Neurology , 264 : 356 – 395 .
  • Jarrard , LE . 1995 . What does the hippocampus really do? . Behavioural Brain Research , 71 : 1 – 10 .
  • Jarrard , LE . 2002 . Use of excitotoxins to lesion the hippocampus: Update . Hippocampus , 12 : 405 – 414 .
  • Lavenex , P , Suzuki , WA and Amaral , DG . 2004 . Perirhinal and parahippocampal cortices of the macaque monkey: Intrinsic projections and interconnections . Journal of Comparative Neurology , 472 : 371 – 394 .
  • Lee , ACH , Barense , MD and Graham , KS . this issue . The contribution of the human medial temporal to perception: Bridging the gap between animal, human studies . Quarterly Journal of Experimental Psychology , 58B : 300 – 325 .
  • Lee , ACH , Bussey , TJ , Murray , EA , Saksida , LM , Epstein , RA Kapur , N . 2005 . Perceptual deficits in amnesia: Challenging the medial temporal lobe ‘mnemonic’ view . Neuropsychologia , 43 : 1 – 11 .
  • Leonard , BW , Amaral , DG , Squire , LR and Zola-Morgan , S . 1995 . Transient memory impairment in monkeys with bilateral lesions of the entorhinal cortex . Journal of Neuroscience , 15 : 5637 – 5659 .
  • Mahut , H . 1971 . Spatial and object reversal learning in monkeys with partial temporal lobe ablations . Neuropsychologia , 9 : 409 – 424 .
  • Mahut , H , Zola-Morgan , S and Moss , M . 1982 . Hippocampal resections impair associative learning and recog-nition memory in the monkey . Journal of Neuroscience , 2 : 1214 – 1229 .
  • Malamut , BL , Saunders , R and Mishkin , M . 1984 . Monkeys with combined amygdalo-hippocampal lesions suceed in object discrimination learning despite 24-hour intertrial intervals . Behavioral Neuroscience , 98 : 759 – 769 .
  • Malkova , L , Gaffan , D and Murray , EA . 1997 . Excitotoxic lesions of the amygdala fail to produce impairment in visual learning for auditory secondary reinforcement but interfere with reinforcer devaluation effects in rhesus monkeys . Journal of Neuroscience , 17 : 6011 – 6020 .
  • Meunier , M , Bachevalier , J , Mishkin , M and Murray , EA . 1993 . Effects on visual recognition of combined and separate ablations of the entorhinal and perirhinal cortex in rhesus monkeys . Journal of Neuroscience , 13 : 5418 – 5432 .
  • Milner B 1958 Psychological defects produced by temporal lobe excision In H. C. Solomon, S. Cobb, & W. Penfield (Eds.), The brain and human behavior. [Research publications of the Association for Research in Nervous and Mental Disease] 244 257 Baltimore The Williams & Wilkins Company
  • Mishkin , M . 1978 . Memory in monkeys severely impaired by combined but not by separate removal of amygdala and hippocampus . Nature , 273 : 297 – 298 .
  • Mishkin , M and Delacour , J . 1975 . An analysis of short-term visual memory in the monkey . Journal of Experimental Psychology: Animal Behavior Processes , 1 : 326 – 334 .
  • Mishkin M Petri HL 1984 Memories and habits: Some implications for the analysis of learning and retention In L. Squire & N. Butters (Eds.) Neuropsychology of memory 1st ed., 287 296 New York Guilford Press
  • Mishkin M Malamut BL Bachevalier J 1984 Memories and habits: Two neural systems In G. Lynch, J. L. McGaugh & N. M. Weinberger (Eds.), Neurobiology of learning and memory New York Guilford Press
  • Morris , RGM , Garrud , P , Rawlins , JNP and O'Keefe , J . 1982 . Place navigation impaired in rats with hippocampal-lesions . Nature , 297 : 681 – 683 .
  • Mumby , DG , Wood , ER , Duva , CA , Kornecook , TJ , Pinel , JPJ and Phillips , AG . 1996 . Ischemia-induced object-recognition deficits in rats are attenuated by hippocampal ablation before or soon after ischemia . Behavioral Neuroscience , 110 : 266 – 281 .
  • Murray , EA , Baxter , MG and Gaffan , D . 1998 . Monkeys with rhinal cortex damage or neurotoxic hippocampal lesions are impaired on spatial scene learning and object reversals . Behavioral Neuroscience , 112 : 1291 – 1303 .
  • Murray , EA and Bussey , TJ . 1999 . Perceptual-mnemonic functions of the perirhinal cortex . Trends in Cognitive Sciences , 3 : 142 – 151 .
  • Murray , EA , Davidson , M , Gaffan , D , Olton , DS and Suomi , S . 1989 . Effects of fornix transection and cingulate cortical ablation on spatial memory in rhesus monkeys . Experimental Brain Research , 74 : 173 – 186 .
  • Murray , EA and Mishkin , M . 1986 . Visual recognition in monkeys following rhinal cortical ablations combined with either amygdalectomy or hippocampectomy . Journal of Neuroscience , 6 : 1991 – 2003 .
  • Murray , EA and Mishkin , M . 1998 . Object recognition and location memory in monkeys with excitotoxic lesions of the amygdala and hippocampus . Journal of Neuroscience , 18 : 6568 – 6582 .
  • Murray , EA and Richmond , BJ . 2001 . Role of perirhinal cortex in object perception, memory, and associations . Current Opinion in Neurobiology , 11 : 188 – 193 .
  • O'Keefe J Nadel L 1978 The hippocampus as a cognitive map London Oxford University Press
  • Orbach , J , Milner , B and Rasmussen , T . 1960 . Learning and retention in monkeys after amygdala-hippocampal resections . Archives of Neurology , 3 : 1214 – 1229 .
  • Reed , JM and Squire , LR . 1998 . Retrograde amnesia for facts and events: Findings from four new cases . Journal of Neuroscience , 18 : 3943 – 3954 .
  • Rempel-Clower , NL , Zola , SM , Squire , LR and Amaral , DG . 1996 . Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation . Journal of Neuroscience , 16 : 5233 – 5255 .
  • Ryan , JD , Althoff , RR , Whitlow , S and Cohen , NJ . 2000 . Amnesia is a deficit in relational memory . Psychological Science , 11 : 454 – 461 .
  • Scoville , WB and Milner , B . 1957 . Loss of recent memory after bilateral hippocampal lesions . Journal of Neurology, Neurosurgery and Psychiatry , 20 : 11 – 21 .
  • Squire , LR and Zola-Morgan , S . 1991 . The medial temporal lobe memory system . Science , 253 : 1380 – 1386 .
  • Suzuki , WA . 1996a . Neuroanatomy of the monkey entorhinal, perirhinal and parahippocampal cortices: Organization of cortical inputs and interconnections with amygdala and striatum . Seminars in the Neurosciences , 8 : 3 – 11 .
  • Suzuki , WA . 1996b . The anatomy, physiology and functions of the perirhinal cortex . Current Opinion in Neurobiology , 6 : 179 – 186 .
  • Suzuki , W , Zola-Morgan , S , Squire , L and Amaral , D . 1993 . Lesions of the perirhinal and parahippocampal cortices in the monkey produce long-lasting memory impairment in the visual and tactual modalities . Journal of Neuroscience , 13 : 2430 – 2451 .
  • Tanaka , K . 1996 . Inferotemporal cortex and object vision . Annual Review of Neuroscience , 19 : 109 – 139 .
  • Van Hoesen , GW , Hyman , BT and Damasio , AR . 1991 . Entorhinal cortex pathology, in Alzheimer's disease . Hippocampus , 1 : 1 – 8 .
  • Zola , SM , Squire , LR , Teng , E , Stefanacci , L , Buffalo , EA and Clark , RE . 2000 . Impaired recognition memory in monkeys after damage limited to the hippocampal region . Journal of Neuroscience , 20 : 451 – 463 .
  • Zola-Morgan , S and Squire , LR . 1986 . Memory impairment in monkeys following lesions limited to the hippocampus . Behavioral Neuroscience , 100 : 155 – 160 .
  • Zola-Morgan , S , Squire , L and Amaral , DG . 1986 . Human amnesia and the medial temporal region-enduring memory impairment following a bilateral lesion limited to field Ca1 of the hippocampus . Journal of Neuroscience , 6 : 2950 – 2967 .
  • Zola-Morgan , S , Squire , L , Clower , R and Rempel , N . 1993 . Damage to the perirhinal cortex exacerbates mem-ory impairment following lesions to the hippocampal formation . Journal of Neuroscience , 13 : 251 – 265 .
  • Zola-Morgan , S , Squire , LR and Mishkin , M . 1982 . The neuroanatomy of amnesia-amygdala-hippocampus versus temporal stem . Science , 218 : 1337 – 1339 .
  • Zola-Morgan , S , Squire , LR and Ramus , SJ . 1994 . Severity of memory impairment in monkeys as a function of locus and extent of damage within the medial temporal-lobe memory system . Hippocampus , 4 : 483 – 495 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.