1,359
Views
36
CrossRef citations to date
0
Altmetric
Review

The management of ventricular dysrhythmia in aconite poisoning

, &
Pages 313-321 | Received 26 Oct 2015, Accepted 19 Jan 2017, Published online: 20 Feb 2017

References

  • Chan TYK. Aconite poisoning. Clin Toxicol. 2009;47:279–285.
  • Sheikh-Zade YR, Cherednik IL, Galenko-Yaroshevskii PA. Peculiarities of cardiotropic effect of aconitine. Bull Exp Biol Med. 2000;129:365–366.
  • Honerjäger P, Meissner A. The positive inotropic effect of aconitine. Naunyn Schmiedebergs Arch Pharmacol. 1983;322:49–58.
  • Yamanaka H, Doi A, Ishibashi H, et al. Aconitine facilitates spontaneous transmitter release at rat ventromedial hypothalamic neurons. Br J Pharmacol. 2002;135:816–822.
  • Friese J, Gleitz J, Gutser UT, et al. Aconitum sp. alkaloids: the modulation of voltage-dependent Na + channels, toxicity and antinociceptive properties. Eur J Pharmacol. 1997;337:165–174.
  • Kimura M, Muroi M, Kimura I, et al. Hypaconitine, the dominant constituent responsible for the neuromuscular blocking action of the Japanese-sino medicine “bushi” (aconite root). Jpn J Pharmacol 1988;48:290–293.
  • Wang Y-J, Chen B-S, Lin M-W, et al. Time-dependent block of ultrarapid-delayed rectifier K + currents by aconitine, a potent cardiotoxin, in heart-derived H9c2 myoblasts and in neonatal rat ventricular myocytes. Toxicol Sci. 2008;106:454–463.
  • Catterall WA. Activation of the action potential Na + ionophore by neurotoxins. An allosteric model. J Biol Chem. 1977;252:8669–8676.
  • Campbell DT. Modified kinetics and selectivity of sodium channels in frog skeletal muscle fibers treated with aconitine. J Gen Physiol. 1982;80:713–731.
  • Sawanobori T, Hirano Y, Hiraoka M. Aconitine-induced delayed afterdepolarization in frog atrium and guinea pig papillary muscles in the presence of low concentrations of Ca2+. Jpn J Physiol. 1987;37:59–79.
  • Kishida H, Saitoh T, Sano J, et al. Prognostic indicators of major cardiac events in patients with asymptomatic coronary artery disease. Jpn Heart J. 1996;37:59–72.
  • Ohno Y, Chiba S, Uchigasaki S, et al. The influence of tetrodotoxin on the toxic effects of aconitine in vivo. Tohoku J Exp Med. 1992;167:155–158.
  • Quevedo M, Pérez-Olea J, Pino C. Prilocaine effect on aconitine-induced arrhythmias. Acta Physiol Lat Am. 1978;28:201–207.
  • Gutiérrez B, Vilumara A, Farré AJ. Inhibition of aconitine-induced mortality in the conscious rat: a screening test for antiarrhythmic drugs. Methods Find Exp Clin Pharmacol. 1987;9:307–310.
  • Zhou Y, Piao X, Liu X, et al. Arrhythmogenesis toxicity of aconitine is related to intracellular Ca2+ signals. Int J Med Sci. 2013;10:1242–1249.
  • Fu M, Li R-X, Fan L, et al. Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias. Biochem Pharmacol. 2008;75:2147–2156.
  • Sun G, Sun H, Meng X, et al. Aconitine-induced Ca2+ overload causes arrhythmia and triggers apoptosis through p38 MAPK signaling pathway in rats. Toxicol Appl Pharmacol. 2014;279:22.
  • Li Y, Tu D, Xiao H, et al. Aconitine blocks HERG and Kv1.5 potassium channels. J Ethnopharmacol. 2010;131:187–195.
  • Shu H, Yi-Ming W, Xu L-P, et al. Increased susceptibility of ventricular arrhythmias to aconitine in anaesthetized rats is attributed to the inhibition of baroreflex. Clin Exp Pharmacol Physiol. 2004;31:249–253.
  • Li M, Wang J, Xie H, et al. The susceptibility of ventricular arrhythmia to aconitine in conscious Lyon hypertensive rats. Acta Pharmacol Sin. 2007;28:211–215.
  • Fujita Y, Terui K, Fujita M, et al. Five cases of aconite poisoning: toxicokinetics of aconitines. J Anal Toxicol. 2007 1;31:132–137.
  • Terui K, Fujita Y, Takei M, et al. Relationship between serum aconitines level and clinical features of aconite poisoning. J Tradit Med 2008;25:67–73.
  • Moritz F, Compagnon P, Kaliszczak IG, et al. Severe acute poisoning with homemade Aconitum napellus capsules: toxicokinetic and clinical data. Clin Toxicol. 2005;43:873–876.
  • Bonnici K, Stanworth D, Simmonds MS, et al. Flowers of evil. Lancet. 2010;376:1616.
  • Yeih D-F, Chiang F-T, Huang SKS. Successful treatment of aconitine induced life threatening ventricular tachyarrhythmia with amiodarone. Heart. 2000;84:e8.
  • Lowe L, Matteucci MJ, Schneir AB. Herbal aconite tea and refractory ventricular tachycardia. N Engl J Med. 2005;353:1532.
  • Gottignies P, El Hor T, Tameze JK, et al. Successful treatment of monkshood (aconite napel) poisoning with magnesium sulfate. Am J Emerg Med. 2009;27:755.e1–4.
  • Tai Y-T, Lau C-P, Young K, et al. Cardiotoxicity after accidental herb-induced aconite poisoning. Lancet. 1992;340:1254–1256.
  • Lin C-C, Chan TYK, Deng J-F. Clinical features and management of herb-induced aconitine poisoning. Ann Emerg Med. 2004;43:574–579.
  • McGregor AC, MacMillian MH, Ferguson J. Potter’s potions. Emerg Med J. 2008;25:217–218.
  • Strzelecki A, Pichon N, Gaulier JM, et al. Acute toxic herbal intake in a suicide attempt and fatal refractory ventricular arrhythmia. Basic Clin Pharmacol Toxicol. 2010;107:698–699.
  • Weijters BJ, Verbunt RJ. a M, Hoogsteen J, et al. Salade malade: malignant ventricular arrhythmias due to an accidental intoxication with Aconitum napellus. NHJL. 2008;16:96–99.
  • Kolev ST, Leman P, Kite GC, et al. Toxicity following accidental ingestion of aconitum containing Chinese remedy. Hum Exp Toxicol. 1996;15:839–842.
  • Fitzpatrick AJ, Crawford M, Allan RM, et al. Aconite poisoning managed with a ventricular assist device. Anaesth Intensive Care. 1994;22:714–717.
  • Agarwal BL, Agarwal RK, Misra DN. Malignant arrhythmias induced by accidental aconite poisoning. Indian Heart J. 1977;29:246–248.
  • Sharma SN, Talwar KK, Bhatia ML. Aconite induced reversible ventricular dysrrhythmia. J Assoc Physicians India. 1990;38:381.
  • Dwivedi S, Aggarwal A, Sharma V. Cardiotoxicity from ‘safe’ herbomineral formulations. Trop Doct. 2011;41:113–115.
  • Gupta BS, Saigal R, Vottery R, et al. Sustained ventricular tachycardia in a case of aconite poisoning. J Assoc Physicians India. 1999;47:455.
  • But PP, Tai YT, Young K. Three fatal cases of herbal aconite poisoning. Vet Hum Toxicol. 1994;36:212–215.
  • Fatovich DM. Aconite: a lethal Chinese herb. Ann Emerg Med. 1992;21:309–311.
  • Poon WT, Lai CK, Ching CK, et al. Aconite poisoning in camouflage. Hong Kong Med J. 2006;12:456–459.
  • Munnecom THC, van Kraaij DJW, van Westreenen JC. Case report: arrhythmia à deux: a poisonous salad for two. Int J Cardiol. 2011;152:e37–e39.
  • Martinez A, Dobos N, Rotella J-A, et al. Life-threatening cardiovascular toxicity following ingestion of Chinese herbal medicine. Emerg Med Australas. 2014;26:512–513.
  • Imazio M, Belli R, Pomari F, et al. Malignant ventricular arrhythmias due to Aconitum napellus seeds. Circulation. 2000;102:2907–2908.
  • Chen X, Wu R, Jin H, et al. Successful rescue of a patient with acute aconitine poisoning complicated by polycystic renal hemorrhage. J Nippon Med Sch. 2015;82:257–261.
  • Tai YT, Lau CP, But PP, et al. Bidirectional tachycardia induced by herbal aconite poisoning. Pacing Clin Electrophysiol. 1992;15:831–839.
  • Smith SW, Shah RR, Hunt JL, et al. Bidirectional ventricular tachycardia resulting from herbal aconite poisoning. Ann Emerg Med. 2005;45:100–101.
  • Holmes B, Heel RC. Flecainide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy. Drugs. 1985;29:1–33.
  • Roden DM, Woosley RL. Drug therapy. Flecainide. N Engl J Med. 1986;315:36–41.
  • Woosley RL, Wang T, Stone W, et al. Pharmacology, electrophysiology, and pharmacokinetics of mexiletine. Am Heart J. 1984;107:1058–1065.
  • Winslow E. Evaluation of antagonism of aconitine-induced dysrhythmias in mice as a method of detecting and assessing antidysrhythmic activity. Br J Pharmacol. 1980;71:615–622.
  • Deakin CD, Nolan JP, Soar J, et al. European resuscitation council guidelines for resuscitation 2010 Section 4. Adult advanced life support. Resuscitation. 2010;81:1305–1352.
  • Nattel S, Talajic M, Fermini B, et al. Amiodarone: pharmacology, clinical actions, and relationships between them. J Cardiovasc Electrophysiol. 1992;3:266–280.
  • Sawanobori T, Adaniya H, Hirano Y, et al. Effects of antiarrhythmic agents and Mg2+ on aconitine-induced arrhythmias. Jpn Heart J. 1996;37:709–718.
  • Sheu SS, Lederer WJ. Lidocaine’s negative inotropic and antiarrhythmic actions. Dependence on shortening of action potential duration and reduction of intracellular sodium activity. Circ Res. 1985;57:578–590.
  • Dosdall DJ, Fast VG, Ideker RE. Mechanisms of defibrillation. Annu Rev Biomed Eng. 2010;12:233–258.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.