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OncoImmunology Volume 12, 2023 - Issue 1
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Cellular senescence enhances adaptive anticancer immunosurveillance

Ines Marina Aging and Metabolism Programme, Institute for Research in Biomedicine (IRB), Barcelona Institute of Science and Technology, Barcelona08028, SpainORCID Iconhttps://orcid.org/0000-0003-0922-0555View further author information
ORCID Icon,
Manuel Serranoa Aging and Metabolism Programme, Institute for Research in Biomedicine (IRB), Barcelona Institute of Science and Technology, Barcelona08028, Spain;b Catalan Institution for Research and Advanced Studies, Barcelona08010, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7177-9312View further author information
ORCID Icon &
Federico Pietrocolac Department of Biosciences and Nutrition, Karolinska Institute, Huddinge14157, SwedenCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2930-234XView further author information
ORCID Icon
Article: 2154115 | Received 24 Nov 2022, Accepted 29 Nov 2022, Published online: 15 Dec 2022

References

  • Marin I, Boix O, Garcia-Garijo A, Sirois I, Caballe A, Zarzuela E, Ruano I, Stephan-Otto Attolini C, Prats N, Lopez-Dominguez JA, et al. Cellular senescence is immunogenic and promotes anti-tumor immunity. Cancer Discov. 2022. doi:10.1158/2159-8290.CD-22-0523.
  • Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013;39(1):1–3. doi:10.1016/j.immuni.2013.07.012.
  • Vanmeerbeek I, Sprooten J, De Ruysscher D, Tejpar S, Vandenberghe P, Fucikova J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L, et al. Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology. Oncoimmunology. 2020;9(1):1703449. doi:10.1080/2162402X.2019.1703449.
  • Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, et al. Cellular senescence: defining a path forward. Cell. 2019;179(4):813–827. doi:10.1016/j.cell.2019.10.005.
  • Sprooten J, Garg AD. Type I interferons and endoplasmic reticulum stress in health and disease. Int Rev Cell Mol Biol. 2020;350:63–118. doi:10.1016/bs.ircmb.2019.10.004.
  • de Verteuil D, Granados DP, Thibault P, Perreault C. Origin and plasticity of MHC I-associated self peptides. Autoimmun Rev. 2012;11(9):627–635. doi:10.1016/j.autrev.2011.11.003.
  • Meng Y, Efimova EV, Hamzeh KW, Darga TE, Mauceri HJ, Fu YX, Kron SJ, Weichselbaum RR. Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Mol Ther. 2012;20(5):1046–1055. doi:10.1038/mt.2012.19.
  • Chen HA, Ho YJ, Mezzadra R, Adrover JM, Smolkin R, Zhu C, Woess K, Bernstein N, Schmitt G, Fong L, et al. Senescence rewires microenvironment sensing to facilitate anti-tumor immunity. Cancer Discov. 2022. doi:10.1158/2159-8290.CD-22-0528.
  • Gilioli D, Fusco S, Tavella T, Giannetti K, Conti A, Santoro A, Carsana E, Beretta S, Schonlein M, Gambacorta V, et al. Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in acute myeloid leukemia. bioRxiv. 2022;2022:515658. doi:10.1101/2022.11.17.515658.
  • Perez CR, De Palma M. Engineering dendritic cell vaccines to improve cancer immunotherapy. Nat Commun. 2019;10(1):5408. doi:10.1038/s41467-019-13368-y.

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