702
Views
0
CrossRef citations to date
0
Altmetric
Original research

Identification and characterization of the anti-viral interferon lambda 3 as direct target of the Epstein-Barr virus microRNA-BART7-3p

, , , , , , & show all
Article: 2284483 | Received 28 Aug 2023, Accepted 13 Nov 2023, Published online: 27 Nov 2023

References

  • Dunmire SK, Verghese PS, Balfour HH Jr. Primary Epstein-Barr virus infection. J Clin Virol. 2018;102:84–10. doi:10.1016/j.jcv.2018.03.001.
  • Bauer M, Jasinski-Bergner S, Mandelboim O, Wickenhauser C, Seliger B. Epstein–Barr Virus—Associated Malignancies and Immune Escape: The Role of the Tumor Microenvironment and Tumor Cell Evasion Strategies. Cancers Basel. 2021;13(20):5189. doi:10.3390/cancers13205189.
  • Pathmanathan R, Prasad U, Sadler R, Flynn K, Raab-Traub N. Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. N Engl J Med. 1995;333(11):693–698. doi:10.1056/NEJM199509143331103.
  • Shibata D, Weiss LM. Epstein-Barr virus-associated gastric adenocarcinoma. Am J Pathol. 1992;140:769–774.
  • Huang X, Nolte I, Gao Z, Vos H, Hepkema B, Poppema S, van den Berg A, Diepstra A, Zhang L. Epidemiology of classical Hodgkin lymphoma and its association with Epstein Barr virus in Northern China. PLoS ONE. 2011;6(6):e21152. doi:10.1371/journal.pone.0021152.
  • Ogwang MD, Bhatia K, Biggar RJ, Mbulaiteye SM. Incidence and geographic distribution of endemic Burkitt lymphoma in northern Uganda revisited. Int J Cancer. 2008;123(11):2658–2663. doi:10.1002/ijc.23800.
  • Jasinski-Bergner S, Blumke J, Bauer M, Skiebe SL, Mandelboim O, Wickenhauser C, Seliger B. Novel approach to identify putative Epstein–Barr–virus microRNAs regulating host cell genes with relevance in tumor biology and immunology. Oncoimmunology. 2022;11(1):2070338. doi:10.1080/2162402X.2022.2070338.
  • Jasinski-Bergner S, Mandelboim O, Seliger B. Molecular mechanisms of human herpes viruses inferring with host immune surveillance. J Immunother Cancer. 2020;8(2):e000841. doi:10.1136/jitc-2020-000841.
  • Thorley-Lawson DA. EBV persistence–introducing the virus. Curr Top Microbiol Immunol. 2015;390(Pt 1):151–209.
  • Xia T, O’Hara A, Araujo I, Barreto J, Carvalho E, Sapucaia JB, Ramos JC, Luz E, Pedroso C, Manrique M, et al. EBV microRNAs in primary lymphomas and targeting of CXCL-11 by ebv-mir-BHRF1-3. Cancer Res. 2008;68(5):1436–1442. doi:10.1158/0008-5472.CAN-07-5126.
  • Albanese M, Tagawa T, Bouvet M, Maliqi L, Lutter D, Hoser J, Hastreiter M, Hayes M, Sugden B, Martin L, et al. Epstein–Barr virus microRNAs reduce immune surveillance by virus-specific CD8 + T cells. Proceedings of the National Academy of Sciences USA. 2016;113(42):E6467–E6475. doi:10.1073/pnas.1605884113.
  • Jasinski-Bergner S, Stoehr C, Bukur J, Massa C, Braun J, Huttelmaier S, Spath V, Wartenberg R, Legal W, Taubert H, et al. Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma. Oncoimmunology. 2015;4(6):e1008805. doi:10.1080/2162402X.2015.1008805.
  • Jasinski-Bergner S, Reches A, Stoehr C, Massa C, Gonschorek E, Huettelmaier S, Braun J, Wach S, Wullich B, Spath V, et al. Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma. Oncotarget. 2016;7(18):26866–78.
  • Jasinski-Bergner S, Mandelboim O, Seliger B. The role of microRNAs in the control of innate immune response in cancer. J Natl Cancer Inst. 2014;106(10): doi:10.1093/jnci/dju257.
  • Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, Nguyen JT, Barbisin M, Xu NL, Mahuvakar VR, Andersen MR, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res. 2005;33(20):e179. doi:10.1093/nar/gni178.
  • WHO classification of tumours of haematopoietic and lymphoid tissues, NLM ID: 101716000, ISBN: 9789283244943.
  • WHO Classification of Head and Neck Tumours. WHO/IARC classification of tumours. Vol. 9. 4th ed. 2017.
  • Wu X, Cheng YL, Matthen M, Yoon A, Schwartz GK, Bala S, Taylor AM, Momen-Heravi F. Down-regulation of the tumor suppressor miR-34a contributes to head and neck cancer by up-regulating the MET oncogene and modulating tumor immune evasion. J Exp Clin Cancer Res. 2021;40(1):70. doi:10.1186/s13046-021-01865-2.
  • Andreakos E, Salagianni M, Galani IE, Koltsida O. Interferon-λs: Front-line Guardians of Immunity and homeostasis in the respiratory tract. Front Immunol. 2017;8:1232. doi:10.3389/fimmu.2017.01232.
  • Rosa F, Berissi H, Weissenbach J, Maroteaux L, Fellous M, Revel M. The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon. EMBO J. 1983;2(2):239–243. doi:10.1002/j.1460-2075.1983.tb01412.x.
  • Rehmsmeier M, Steffen P, Hochsmann M, Giegerich R. Fast and effective prediction of microRNA/target duplexes. RNA. 2004;10(10):1507–1517. doi:10.1261/rna.5248604.
  • Tierney RJ, Shannon-Lowe CD, Fitzsimmons L, Bell AI, Rowe M. Unexpected patterns of Epstein–Barr virus transcription revealed by a high throughput PCR array for absolute quantification of viral mRNA. Virology. 2015;474:117–130. doi:10.1016/j.virol.2014.10.030.
  • Kang MS, Kieff E. Epstein–Barr virus latent genes. Experimental & Molecular Medicine. 2015;47(1):e131. doi:10.1038/emm.2014.84.
  • Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Chang I, Tanaka Y, Gupta A, Dahiya R. MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. Carcinogenesis. 2012;33(2):294–300. doi:10.1093/carcin/bgr286.
  • Hong DS, Kang YK, Borad M, Sachdev J, Ejadi S, Lim HY, Brenner AJ, Park K, Lee JL, Kim TY, et al. Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours. Br J Cancer. 2020;122(11):1630–1637. doi:10.1038/s41416-020-0802-1.
  • Peterson ST, Kennedy EA, Brigleb PH, Taylor GM, Urbanek K, Bricker TL, Lee S, Shin H, Dermody TS, Boon ACM, et al. Disruption of type III interferon (IFN) genes Ifnl2 and Ifnl3 recapitulates loss of the type III IFN receptor in the mucosal antiviral response. J Virol. 2019;93(22). doi:10.1128/JVI.01073-19.
  • Walker FC, Sridhar PR, Baldridge MT. Differential roles of interferons in innate responses to mucosal viral infections. Trends Immunol. 2021;42(11):1009–1023. doi:10.1016/j.it.2021.09.003.