Streptococcus mutans levels in patients who received orthodontic brackets bonded using probiotic impregnated resin composite – a randomized clinical trial

References

• Bishara SE, Ostby AW. White spot lesions: formation, prevention, and treatment. Sem Orthod. 2008;14(3):174–182.
   Google Scholar
• Jing D, Hao J, Shen Y, et al. Effect of fixed orthodontic treatment on oral microbiota and salivary proteins. Exp Ther Med. 2019 1;17(5):4237–4243.
   PubMed Web of Science ®Google Scholar
• Tufekci E, Dixon JS, Gunsolley JC, et al. Prevalence of white spot lesions during orthodontic treatment with fixed appliances. Angle Orthod. 2011;81(2):206–210, 201.
   PubMed Web of Science ®Google Scholar
• Mizrahi E. Enamel demineralization following orthodontic treatment. Am J Orthod. 1982;82(1):62–67.
   PubMedGoogle Scholar
• Chapman RA, Roberts WE, Eckert GJ, et al. Risk factors for incidence and severity of white spot lesions during treatment with fixed orthodontic appliances. Am J Orthod Dentofacial Orthop. 2010;138(2):188–194.
   PubMed Web of Science ®Google Scholar
• Sonesson M, Twetman S, Bondemark L. Effectiveness of high-fluoride toothpaste on enamel demineralization during orthodontic treatment – a multicenter randomized controlled trial. Eur J Orthod. 2014;36(6):678–682.
   PubMed Web of Science ®Google Scholar
• Kau CH, Wang J, Palombini A, et al. Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: a randomized trial. Angle Orthod. 2019;89(3):365–371.
   PubMed Web of Science ®Google Scholar
• van der Kaaij NC, van der Veen MH, van der Kaaij MA, et al. A prospective, randomized placebo-controlled clinical trial on the effects of a fluoride rinse on white spot lesion development and bleeding in orthodontic patients. Eur J Oral Sci. 2015;123(3):186–193.
   PubMed Web of Science ®Google Scholar
• Perrini F, Lombardo L, Arreghini A, et al. Caries prevention during orthodontic treatment: in-vivo assessment of high-fluoride varnish to prevent white spot lesions. Am J Orthod Dentofacial Orthop. 2016;149(2):238–243.
   PubMed Web of Science ®Google Scholar
• Kirschneck C, Christl JJ, Reicheneder C, et al. Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances—a prospective randomized controlled trial. Clin Oral Investig. 2016;20(9):2371–2378.
   PubMed Web of Science ®Google Scholar
• Hoffman DA, Clark AE, Rody WJ, et al. A prospective randomized clinical trial into the capacity of a toothpaste containing NovaMin to prevent white spot lesions and gingivitis during orthodontic treatment. Prog Orthod. 2015;16:25.
   PubMed Web of Science ®Google Scholar
• Rechmann P, Bekmezian S, Rechmann BMT, et al. MI varnish and MI paste plus in a caries prevention and remineralization study: a randomized controlled trial. Clin Oral Investig. 2018;22(6):2229–2239.
   PubMed Web of Science ®Google Scholar
• Korkmaz YN, Yagci A. Comparing the effects of three different fluoride-releasing agents on white spot lesion prevention in patients treated with full coverage rapid maxillary expanders. Clin Oral Investig. 2019;23(8):3275–3285.
   PubMed Web of Science ®Google Scholar
• Shimpo Y, Nomura Y, Sekiya T, et al. Effects of the dental caries preventive procedure on the white spot lesions during orthodontic treatment—an open label randomized controlled trial. J Clin Med. 2022;11(3):854.
   PubMed Web of Science ®Google Scholar
• Gokce G, Savas S, Kucukyilmaz E, et al. Effects of toothpastes on white spot lesions around orthodontic brackets using quantitative light-induced fluorescence (QLF): an in vitro study. J Orofac Orthop. 2017;78(6):480–486.
   PubMed Web of Science ®Google Scholar
• Gizani S, Petsi G, Twetman S, et al. Effect of the probiotic bacterium Lactobacillus reuteri on white spot lesion development in orthodontic patients. Eur J Orthod. 2016;38(1):85–89.
   PubMed Web of Science ®Google Scholar
• Çaglar E, Kuscu OO, Cildir SK, et al. A probiotic lozenge administered medical device and its effect on salivary mutans streptococci and lactobacilli. Int J Paed Dent. 2008;18(1):35–39.
   PubMed Web of Science ®Google Scholar
• Cildir SK, Germec D, Sandalli N, et al. Reduction of salivary mutans streptococci in orthodontic patients during daily consumption of yoghurt containing probiotic bacteria. Eur J Orthod. 2009;31(4):407–411.
   PubMed Web of Science ®Google Scholar
• Pinto GS, Cenci MS, Azevedo MS, et al. Effect of yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 probiotic on dental plaque and saliva in orthodontic patients. Caries Res. 2014;48(1):63–68.
   PubMed Web of Science ®Google Scholar
• Bafna HP, Ajithkrishnan CG, Kalantharakath T, et al. Effect of short-term consumption of amul probiotic yogurt containing Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 on salivary Streptococcus mutans count in high caries risk individuals. Int J Appl Basic Med Res. 2018;8(2):111–116.
   PubMedGoogle Scholar
• Jose JE, Padmanabhan S, Chitharanjan AB. Systemic consumption of probiotic curd and use of probiotic toothpaste to reduce Streptococcus mutans in plaque around orthodontic brackets. Am J Orthod Dentofacial Orthop. 2013;144(1):67–72.
   PubMed Web of Science ®Google Scholar
• Rastogi P, Saini H, Dixit J, et al. Probiotics and oral health. Natl J Maxillofac Surg. 2011;2(1):6–9.
   PubMedGoogle Scholar
• Çaglar E, Cildir SK, Ergeneli S, et al. Salivary mutans streptococci and lactobacilli levels after ingestion of the probiotic bacterium Lactobacillus reuteri ATCC 55730 by straws or tablets. Acta Odontol Scand. 2006;64(5):314–318.
   PubMed Web of Science ®Google Scholar
• Çaglar E, Onder Kuscu O, Kuvvetli SS, et al. Short-term effect of ice-cream containing Bifidobacterium lactis Bb-12 on the number of salivary mutans streptococci and lactobacilli. Acta Odontol Scand. 2008;66(3):154–158.
   PubMed Web of Science ®Google Scholar
• Yousuf A, Sidiq M, Ganta S, et al. Effect of freeze-dried powdered probiotics on gingival status and plaque inhibition: a randomized, double-blind, parallel study. Contemp Clin Dent. 2017;8(1):116–122.
   PubMed Web of Science ®Google Scholar
• Corcoran BM, Stanton C, Fitzgerald GF, et al. Survival of probiotic lactobacilli in acidic environments is enhanced in the presence of metabolizable sugars. Appl Environ Microbiol. 2005;71(6):3060–3067.
   PubMed Web of Science ®Google Scholar
• Bovo F, Franco LT, Rosim RE, et al. Ability of a Lactobacillus rhamnosus strain cultured in milk whey based medium to bind aflatoxin B1. Food Sci Technol. 2014;34(3):566–570.
   Web of Science ®Google Scholar
• Brown ML, Davis HB, Tufekci E, et al. Ion release from a novel orthodontic resin bonding agent for the reduction and/or prevention of white spot lesions: an in vitro study. Angle Orthod. 2011;81(6):1014–1020.
   PubMed Web of Science ®Google Scholar
• Manfred L, Covell DA, Crowe JJ, et al. A novel biomimetic orthodontic bonding agent helps prevent white spot lesions adjacent to brackets. Angle Orthod. 2013;83(1):97–103.
   PubMed Web of Science ®Google Scholar
• Alshammari FM, Sanea JA. Efficacy of amorphous calcium phosphate (ACP) containing adhesive in preventing demineralization during orthodontic treatment, a triple blinded randomized clinical trial (RCT). J Contemp Dent Pract. 2019;20:727–731.
   PubMedGoogle Scholar
• Comert S, Oz A. A. Clinical effect of a fluoride-releasing and rechargeable primer in reducing white spot lesions during orthodontic treatment. Am J Orthod Dentofacial Orthop. 2020;157(1):P67–72.
   PubMed Web of Science ®Google Scholar
• Amaechi BT, McGarrell B, Luong MN, et al. Prevention of white spot lesions around orthodontic brackets using organoselenium-containing antimicrobial enamel surface sealant. Heliyon. 2021;17(3):e06490.
   Google Scholar
• Nase L, Hatakka K, Savilahti E, et al. Effect of long-term consumption of a probiotic bacterium Lactobacillus rhamnosus GG, in milk on dental caries and caries risk in children. Caries Res. 2001;35:412–420.
   PubMed Web of Science ®Google Scholar
• Lapinska B, Konieczka M, Zarzycka B, et al. Flow cytometry analysis of antibacterial effects of universal dentin bonding agents on Streptococcus mutans. Molecules. 2019;24(3):532.
   PubMed Web of Science ®Google Scholar
• Tanner AC, Sonis AL, Lif Holgerson P, et al. White-spot lesions and gingivitis microbiotas in orthodontic patients. J Dent Res. 2012;91(9):853–858.
   PubMed Web of Science ®Google Scholar
• Beerens MW, Ten Cate J, van der Veen MH. Microbial profile of dental plaque associated to white spot lesions in orthodontic patients immediately after the bracket removal. Arch Oral Biol. 2017;78:88–93.
   PubMed Web of Science ®Google Scholar