An Evidence-Based Systematic Review of Rosemary (Rosmarinus officinalis) by the Natural Standard Research Collaboration

REFERENCES

• Abascal K, Yarnell E. Herbs and breast cancer: research review of seaweed, rosemary and ginseng. Alt Complement Ther. 2001;6:32–36.
   Google Scholar
• Abascal K, Yarnell E. A botanical approach to Alzheimer's disease. Nat Pharm. 2004a;8:1–17.
   Google Scholar
• Abascal K, Yarnell E. Alzheimer's disease –Part 2 –A botanical treatment plan. Altern. Complement Ther. 2004b;10:67–72.
   Google Scholar
• Abdel-Fatah MK, El-Hawa MA, Samia EM, Rabie G, Amer AM. Antimicrobial activities of some local medicinal plants. J Drug Res. 2002;24:179–186.
   Google Scholar
• Abdul-Ghani AS, El-Lati SG, Sacaan AI, Suleiman MS, Amin RM. Anticonvulsant effects of some Arab medicinal plants. Int J Crude Drug Res. 1987;25:39–43.
   Google Scholar
• Abe F, Yamauchi T, Nagao T, Kinjo J, Okabe H, Higo H, Akahane H. Ursolic acid as a trypanocidal constituent in rosemary. Biol Pharm Bull. 2002;25:1485–1487.
   PubMed Web of Science ®Google Scholar
• Adams M, Gmunder F, Hamburger M. Plants traditionally used in age-related brain disorders—a survey of ethnobotanical literature. J Ethnopharmacol. 2007;113:363–381.
   PubMed Web of Science ®Google Scholar
• Adsersen A, Gauguin B, Gudiksen L, Jager AK. Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity. J Ethnopharmacol. 2006;104:418–422.
   PubMed Web of Science ®Google Scholar
• Aggarwal BB, Kunnumakkara AB, Harikumar KB, Tharakan ST, Sung B, Anand P. Potential of spice-derived phytochemicals for cancer prevention. Planta Med. 2008;74:1560– 1569.
   PubMed Web of Science ®Google Scholar
• Aggarwal BB, Shishodia S. Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning. Ann NY Acad Sci. 2004;1030:434–441.
   PubMed Web of Science ®Google Scholar
• Aherne SA, Kerry JP, O'Brien NM. Effects of plant extracts on antioxidant status and oxidant-induced stress in Caco-2 cells. Br. J Nutr. 2007;97:321–328.
   PubMed Web of Science ®Google Scholar
• Ahn J, Grun IU, Mustapha A. Antimicrobial and antioxidant activities of natural extracts in vitro and in ground beef. J Food Prot. 2004;67:148–155.
   PubMed Web of Science ®Google Scholar
• Ahn J, Grun IU, Mustapha A. Effects of plant extracts on microbial growth, color change, and lipid oxidation in cooked beef. Food Microbiol. 2007;24:7–14.
   PubMed Web of Science ®Google Scholar
• Akbar W, Lord JC, Nechols JR, Loughin TM. Efficacy of Bauveria bassiana for red flour beetle when applied with plant essential oils or in mineral oil and organosilicone carriers. J Econ Entomol. 2005;98:683–688.
   PubMed Web of Science ®Google Scholar
• al Hader AA, Hasan ZA, Aqel MB. Hyperglycemic and insulin release inhibitory effects of Rosmarinus officinalis. J Ethnopharmacol. 1994;43:217–221.
   PubMedGoogle Scholar
• Al Qura'n S. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan. J Ethnopharmacol. 2009;123:45–50.
   PubMedGoogle Scholar
• al Sereiti MR, Abu-Amer KM, Sen P. Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. Indian J Exp Biol. 1999;37:124–130.
   PubMedGoogle Scholar
• Albu S, Joyce E, Paniwnyk L, Lorimer JP, Mason TJ. Potential for the use of ultrasound in the extraction of antioxidants from Rosmarinus officinalis for the food and pharmaceutical industry. Ultrason Sonochem. 2004;11:261–265.
   PubMed Web of Science ®Google Scholar
• Aleisa AM. Cytological and biochemical effects of St. John's Wort supplement (a complex mixture of St. John's Wort, Rosemary, and Spirulina) on somatic and germ cells of Swiss Albino mice. Int J Environ Res Public Health 2008;5:408–417.
   PubMedGoogle Scholar
• Alippi AM, Ringuelet JA, Cerimele EL, Re MS, Henning CP. Antimicrobial activity of some essential oils against Paenibacillus larvae, the causal agent of American foulbrood disease. J Herbs, Spices, Med Plants 1996;4:9–16.
   Google Scholar
• Almela L, Sanchez-Munoz B, Fernandez-Lopez JA, Roca MJ, Rabe V. Liquid chromatograpic-mass spectrometric analysis of phenolics and free radical scavenging activity of rosemary extract from different raw material. J Chromatogr. A 2006;1120:221–229.
   PubMed Web of Science ®Google Scholar
• Altinier G, Sosa S, Aquino RP, Mencherini T, Della LR, Tubaro A. Characterization of topical anti-inflammatory compounds in Rosmarinus officinalis L. J Agric Food Chem. 2007;55:1718–1723.
   PubMed Web of Science ®Google Scholar
• Amin A, Hamza AA. Hepatoprotective effects of Hibiscus, Rosmarinus, and Salvia on azathioprine-induced toxicity in rats. Life Sci. 2005;77:266–278.
   PubMed Web of Science ®Google Scholar
• Angelini LG, Carpanese G, Cioni PL, Morelli I, Macchia M, Flamini G. Essential oils from Mediterranean lamiaceae as weed germination inhibitors. J Agric. Food Chem. 2003;51:6158–6164.
   PubMed Web of Science ®Google Scholar
• Angioni A, Barra A, Cereti E, Barile D, Coisson JD, Arlorio M, Dessi S, Coroneo V, Cabras P. Cchemical composition, plant genetic differences, antimicrobial and antifungal activity investigation of the essential oil of Rosmarinus officinalis L. J Agric Food Chem. 2004;52:3530–3535.
   PubMed Web of Science ®Google Scholar
• Antonio CM, Abriouel H, Lopez RL, Omar NB, Valdivia E, Galvez A. Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad. Food Chem Toxicol. 2009;47:2216–2223.
   PubMed Web of Science ®Google Scholar
• Aqel MB. Relaxant effect of the volatile oil of Rosmarinus officinalis on tracheal smooth muscle. J Ethnopharmacol. 1991;33:57–62.
   PubMedGoogle Scholar
• Ariana A, Ebadi R, Tahmasebi G. Laboratory evaluation of some plant essences to control Varroa destructor (Acari: varroidae). Exp Appl Acarol. 2002;27:319–327.
   PubMed Web of Science ®Google Scholar
• Arican E. Inhibition of crown-gall tumorigenesis with plant extracts. Pharm Biol. 2009;47:463–466.
   Web of Science ®Google Scholar
• Armisen M, Rodriguez V, Vidal C. Photoaggravated allergic contact dermatitis due to Rosmarinus officinalis cross-reactive with Thymus vulgaris. Contact Derm. 2003;48:52–53.
   PubMedGoogle Scholar
• Arraez-Roman D, Gomez-Caravaca AM, Gomez-Romero M, Segura-Carretero A, Fernandez-Gutierrez A. Identification of phenolic compounds in rosemary honey using solid-phase extraction by capillary electrophoresis-electrospray ionization-mass spectrometry. J Pharm Biomed Anal. 2006;41:1648–1656.
   PubMed Web of Science ®Google Scholar
• Arslan D, Musa Ozcan M. Evaluation of drying methods with respect to drying kinetics, mineral content, and colour characteristics of rosemary leaves. Energ Convers Manag. 2008;49:1258–1264.
   Web of Science ®Google Scholar
• Artico M, Cervoni L, Nucci F, Giuffre R. Birthday of peripheral nervous system surgery: the contribution of Gabriele Ferrara (1543–1627). Neurosurgery 1996;39:380–382.
   PubMed Web of Science ®Google Scholar
• Aruoma OI. Antioxidant actions of plant foods: use of oxidative DNA damage as a tool for studying antioxidant efficacy. Free Radic Res. 1999;30:419–427.
   PubMed Web of Science ®Google Scholar
• Aruoma OI, Halliwell B, Aeschbach R, Loligers J. Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid. Xenobiotica 1992;22:257–268.
   PubMed Web of Science ®Google Scholar
• Aruoma OI, Spencer JP, Rossi R, Aeschbach R, Khan A, Mahmood N, Munoz A, Murcia A, Butler J, Halliwell B. An evaluation of the antioxidant and antiviral action of extracts of rosemary and Provencal herbs. Food Chem Toxicol. 1996;34:449–456.
   PubMed Web of Science ®Google Scholar
• Asai A, Nakagawa K, Miyazawa T. Antioxidative effects of turmeric, rosemary, and capsicum extracts on membrane phospholipid peroxidation and liver lipid metabolism in mice. Biosci Biotechnol Biochem. 1999;63:2118–2122.
   PubMed Web of Science ®Google Scholar
• Atsumi T, Tonosaki K. Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva. Psychiatry Res. 2007;150:89–96.
   Google Scholar
• Awney HA, Sindi H. The effect of rosemary on the mutagenic activity of heterocyclic amines extracted from common food consumed in Saudi Arabia. Int J Food Sci Nutr. 2010;61:192–203.
   PubMed Web of Science ®Google Scholar
• Ayadi MA, Grati-Kamoun N, Attia H. Physico-chemical change and heat stability of extra virgin olive oils flavoured by selected Tunisian aromatic plants. Food Chem Toxicol. 2009;47:2613–2619.
   PubMed Web of Science ®Google Scholar
• Baardseth P. Effect of selected antioxidants on the stability of dehydrated mashed potatoes. Food Addit Contam. 1989;6:201–207.
   PubMedGoogle Scholar
• Babu US, Wiesenfeld PL, Jenkins MY. Effect of dietary rosemary extract on cell-mediated immunity of young rats. Plant Foods Hum Nutr. 1999;53:169–174.
   PubMedGoogle Scholar
• Backleh M, Leupold G, Parlar H. Rapid quantitative enrichment of carnosic acid from rosemary (Rosmarinus officinalis L.) by isoelectric focused adsorptive bubble chromatography. J Agric Food Chem. 2003;51:1297–1301.
   PubMed Web of Science ®Google Scholar
• Bagamboula CF, Uyttendaele M, Debevere J. Inhibitory effects of spices and herbs toward Shigella sonnei and S. flexneri. Meded. Rijksuniv. Gent Fak. Landbouwkd. Toegep Biol Wet. 2001;66:523–530.
   PubMedGoogle Scholar
• Bagamboula CF, Uyttendaele M, Debevere J. Antimicrobial effect of spices and herbs on Shigella sonnei and Shigella flexneri. J Food Prot. 2003;66:668–673.
   PubMed Web of Science ®Google Scholar
• Bajer T, Adam M, Galla L, Ventura K. Comparison of various extraction techniques for isolation and determination of isoflavonoids in plants. J Sep Sci. 2007;30:122–127.
   PubMed Web of Science ®Google Scholar
• Bakirel T, Bakirel U, Keles OU, Ulgen SG, Yardibi H. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. J Ethnopharmacol. 2008;116:64–73.
   PubMed Web of Science ®Google Scholar
• Ball LJ, Shoker J, Miles JN. Odour-based context reinstatement effects with indirect measures of memory: the curious case of rosemary. Br J Psychol. 2009 (E-pub ahead of print).
   PubMedGoogle Scholar
• Balogh Z, Gray JI, Gomaa EA, Booren AM. Formation and inhibition of heterocyclic aromatic amines in fried ground beef patties. Food Chem Toxicol. 2000;38:395–401.
   PubMed Web of Science ®Google Scholar
• Bassani V, Casadebaig J, Jacob M, Menut C, Lamaty G. Preparation of a low-alcohol extract of Rosmarinus officinalis using a reverse osmosis membrane. Int J Pharm. 1990;63:57–63.
   Google Scholar
• Baumann LS. Less-known botanical cosmeceuticals. Dermatol Ther. 2007;20:330–342.
   PubMedGoogle Scholar
• Baylac S, Racine P. Inhibition of human leukocyte elastase by natural fragrant extracts of aromatic plants. Int J Aromather. 2004;14:179–182.
   Google Scholar
• Beaulieu JE. Herbal therapy interactions with immunosuppressive agents. US Pharmacist. 2001;26:13–22.
   Google Scholar
• Beddows CG, Jagait C, Kelly MJ. Preservation of alpha-tocopherol in sunflower oil by herbs and spices. Int J Food Sci Nutr. 2000;51:327–339.
   PubMed Web of Science ®Google Scholar
• Benhabiles NE, Ait-Amar H, Boutekdjiret C, Belabbes R. Comparative study of Algeria's Rosmarinus eriocalyx and Rosmarinus officinalis L. Perfum. Flavor. 2001;26:40–48.
   Google Scholar
• Bentayeb K, Rubio C, Batlle R, Nerin C. Direct determination of carnosic acid in a new active packaging based on natural extract of rosemary. Anal. Bioanal. Chem. 2007;389:1989–1996.
   PubMed Web of Science ®Google Scholar
• Bentayeb K, Vera P, Rubio C, Nerin C. Adaptation of the ORAC assay to the common laboratory equipment and subsequent application to antioxidant plastic films. Anal. Bioanal. Chem. 2009;394:903–910.
   PubMed Web of Science ®Google Scholar
• Bezanger BL, Guilbert N. On the flavonoids in rosemary leaves. C. R. Hebd. Seances Acad Sci. 1965;260:3202–3203.
   PubMedGoogle Scholar
• Bhale SD, Xu Z, Prinyawiwatkul W, King JM, Godber JS. Oregano and rosemary extracts inhibit oxidation of long-chain N-3 fatty acids in menhaden oil. J Food Sci. 2007;72:C504–C508.
   PubMed Web of Science ®Google Scholar
• Bogdadi H, Abdelsalam A, Kokoska L, Havlik J, Kloucek P, Rada V, Vorisek K. In vitro antimicrobial activity of some Libyan medicinal plant extracts. Pharm Biol. 2007;45:386–391.
   Web of Science ®Google Scholar
• Boot C, Mayer J. 2 new finds in the old German delivery of the rosemary treatise. Sudhoffs Arch. 1990;74:104–111.
   PubMedGoogle Scholar
• Botsoglou NA, Govaris A, Giannenas I, Botsoglou E, Papageorgiou G. The incorporation of dehydrated rosemary leaves in the rations of turkeys and their impact on the oxidative stability of the produced raw and cooked meat. Int J Food Sci Nutr. 2007;58:312–320.
   PubMed Web of Science ®Google Scholar
• Boyraz N, Ozcan M. Antifungal effect of some spice hydrosols. Fitoterapia. 2005;76:661–665.
   PubMed Web of Science ®Google Scholar
• Bozin B, Mimica-Dukic N, Samojlik I, Jovin E. Antimicrobial and antioxidant properties of rosemary and sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils. J Agric Food Chem. 2007;55:7879–7885.
   PubMed Web of Science ®Google Scholar
• Brieskorn CH, Domling HJ. On the presence of 5-hydroxy-7, 4′-dimethoxyflavone in the leaves of Rosmarinus officinalis L. Arch Pharm Ber Dtsch Pharm Ges. 1967;300:1042–1044.
   PubMedGoogle Scholar
• Brieskorn CH, Zweyrohn G. Incidence of 3 further triterpene acids in the leaves of Rosmarinus officinalis L. Pharmazie. 1970;25:488–490.
   PubMedGoogle Scholar
• Brooks JC, Alvarado M, Stephens TP, Kellermeier JD, Tittor AW, Miller MF, Brashears MM. Spoilage and safety characteristics of ground beef packaged in traditional and modified atmosphere packages. J Food Prot. 2008;71:293–301.
   PubMed Web of Science ®Google Scholar
• Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol. 1999;246:667–670.
   PubMed Web of Science ®Google Scholar
• Burnett KM, Solterbeck LA, Strapp CM. Scent and mood state following an anxiety-provoking task. Psychol Rep. 2004;95:707–722.
   PubMed Web of Science ®Google Scholar
• Calabrese V, Scapagnini G, Catalano C, Bates TE, Dinotta F, Micali G, Giuffrida Stella AM. Induction of heat shock protein synthesis in human skin fibroblasts in response to oxidative stress: regulation by a natural antioxidant from rosemary extract. Int J Tissue React. 2001;23:51–58.
   PubMedGoogle Scholar
• Calabrese V, Scapagnini G, Catalano C, Dinotta F, Geraci D, Morganti P. Biochemical studies of a natural antioxidant isolated from rosemary and its application in cosmetic dermatology. Int J Tissue React. 2000;22:5–13.
   PubMedGoogle Scholar
• Calucci L, Pinzino C, Zandomeneghi M, Capocchi A, Ghiringhelli S, Saviozzi F, Tozzi S, Galleschi L. Effects of gamma-irradiation on the free radical and antioxidant contents in nine aromatic herbs and spices. J Agric Food Chem. 2003;51:927–934.
   PubMed Web of Science ®Google Scholar
• Campbell W, Drake MA, Larick DK. The impact of fortification with conjugated linoleic acid (CLA) on the quality of fluid milk. J Dairy Sci. 2003;86:43–51.
   PubMed Web of Science ®Google Scholar
• Cantrell CL, Richheimer SL, Nicholas GM, Schmidt BK, Bailey DT. Seco-Hinokiol, a new abietane diterpenoid from Rosmarinus officinalis. J Nat Prod. 2005;68:98–100.
   PubMedGoogle Scholar
• Carraminana JJ, Rota C, Burillo J, Herrera A. Antibacterial efficiency of Spanish Satureja montana essential oil against Listeria monocytogenes among natural flora in minced pork. J Food Prot. 2008;71:502–508.
   PubMed Web of Science ®Google Scholar
• Carrillo JD, Tena MT. Determination of volatile compounds in antioxidant rosemary extracts by solid-phase microextraction and gas chromatography. Anal Lett. 2005;38:1193–1212.
   Web of Science ®Google Scholar
• Castrillo M, Vizcaino D, Moreno E, Latorraca Z. Specific leaf mass, fresh: dry weight ratio sugar and protein contents in species of Lamiaceae from different light environments. Rev Biol Trop. 2005;53:23–28.
   PubMedGoogle Scholar
• Cervellati R, Renzulli C, Guerra MC, Speroni E. Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method. J Agric. Food Chem. 2002;50:7504–7509.
   PubMed Web of Science ®Google Scholar
• Chan MM, Ho CT, Huang HI. Effects of three dietary phytochemicals from tea, rosemary, and turmeric on inflammation-induced nitrite production. Cancer Lett. 1995;96:23–29.
   PubMed Web of Science ®Google Scholar
• Chang CH, Chyau CC, Hsieh CL, Wu YY, Ker YB, Tsen HY, Peng RY. Relevance of phenolic diterpene constituents to antioxidant activity of supercritical CO2 extract from the leaves of rosemary. Nat Prod Res. 2008;22:76–90.
   PubMed Web of Science ®Google Scholar
• Chang MH, Chen TC. “Hotness” stability of chicken hot-wing products as affected by preparation methods and storage. Poult Sci. 1998;77:627–631.
   PubMedGoogle Scholar
• Cheng SC, Huang MZ, Shiea J. Thin-layer chromatography/laser-induced acoustic desorption/electrospray ionization mass spectrometry. Anal Chem. 2009;81:9274–9281.
   PubMedGoogle Scholar
• Cheung S, Tai J. Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. Oncol Rep. 2007;17:1525–1531.
   PubMed Web of Science ®Google Scholar
• Chohan M, Forster-Wilkins G, Opara EI. Determination of the antioxidant capacity of culinary herbs subjected to various cooking and storage processes using the ABTS(*+) radical cation assay. Plant Foods Hum Nutr. 2008;63:47–52.
   PubMed Web of Science ®Google Scholar
• Choi HR, Choi JS, Han YN, Bae SJ, Chung HY. Peroxynitrite scavenging activity of herb extracts. Phytother Res. 2002a;16:364–367.
   PubMed Web of Science ®Google Scholar
• Choi WS, Park BS, Ku SK, Lee SE. Repellent activities of essential oils and monoterpenes against Culex pipiens pallens. J Am Mosq Control Assoc. 2002b;18:348–351.
   PubMed Web of Science ®Google Scholar
• Cloyd RA, Galle CL, Keith SR, Kalscheur NA, Kemp KE. Effect of commercially available plant-derived essential oil products on arthropod pests. J Econ Entomol. 2009a;102:1567–1579.
   PubMed Web of Science ®Google Scholar
• Cloyd RA, Timmons NR, Goebel JM, Kemp KE. Effect of pesticides on adult rove beetle Atheta coriaria (Coleoptera: staphylinidae) survival in growing medium. J Econ Entomol. 2009b;102:1750–1758.
   PubMedGoogle Scholar
• Cordeiro CH, do Sacramento LV, Correa MA, Pizzolitto AC, Bauab TM. Herbal extracts in an experimental mouthwash: pharmacognostics analysis and antibacterial activity. Braz J Pharm Sci. 2006;42:395–404.
   Google Scholar
• Costa S, Utan A, Speroni E, Cervellati R, Piva G, Prandini A, Guerra MC. Carnosic acid from rosemary extracts: a potential chemoprotective agent against aflatoxin B1. An in vitro study. J Appl Toxicol. 2007;27:152–159.
   PubMed Web of Science ®Google Scholar
• Cross DE, Acamovic T, McDevitt, RM. The productive performance of chicks from 0–21 days, when fed diets containing secondary plant compounds in the presence of an enzyme. Br Poult Sci. 2004a;45(Suppl 1):S50–S51.
   Google Scholar
• Cross DE, McDevitt RM, Acamovic T. Phytochemicals in broiler diets and their effect on nutrient digestibility at 21 days of age. Br Poult Sci. 2004b;45(Suppl 1):S49–S50.
   PubMedGoogle Scholar
• Cross DE, McDevitt RM, Hillman K, Acamovic T. The effect of herbs and their associated essential oils on performance, dietary digestibility and gut microflora in chickens from 7 to 28 days of age. Br Poult Sci. 2007;48:496–506.
   PubMed Web of Science ®Google Scholar
• Croteau R, Kolattukudy PE. Biosynthesis of pentahydroxystearic acid of cutin from linoleic acid in Rosmarinus officinalis. Arch Biochem Biophys. 1974;162:458–470.
   PubMedGoogle Scholar
• Culotta L, Melati MR, Orecchio S. The use of leaves of Rosmarinus officinalis L. as samplers for polycyclic aromatic hydrocarbons. Assessment of air quality in the area of Palermo. Ann Chim. 2002;92:837–845.
   PubMed Web of Science ®Google Scholar
• Cuppett S, Hall C, III, Conway H, Birt D, Lawson T. Inhibition of the mutagenicity of alkylating agents by rosmariquinone, a component of Rosmarinus officinalis L. Cancer Prev Int. 1995;2:25–31.
   Google Scholar
• da Silva LV, Prinyawiwatkul W, King JM, No HK, Bankston JD, Jr, Ge B. Effect of preservatives on microbial safety and quality of smoked blue catfish (Ictalurus furcatus) steaks during room-temperature storage. Food Microbiol. 2008;25:958–963.
   PubMed Web of Science ®Google Scholar
• Daferera DJ, Ziogas BN, Polissiou MG. GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum. J Agric Food Chem. 2000;48:2576–2581.
   PubMed Web of Science ®Google Scholar
• de la FE, Martinez-Castro I, Sanz J. Characterization of Spanish unifloral honeys by solid phase microextraction and gas chromatography-mass spectrometry. J Sep Sci. 2005;28:1093–1100.
   PubMedGoogle Scholar
• de Loreto ES, Pozzatti P, Alves SL, Santurio D, Morais SJ, Alves SH. Differentiation of Candida dubliniensis from Candida albicans on rosemary extract agar and oregano extract agar. J Clin Lab Anal. 2008;22:172–177.
   PubMedGoogle Scholar
• Dearlove RP, Greenspan P, Hartle DK, Swanson RB, Hargrove JL. Inhibition of protein glycation by extracts of culinary herbs and spices. J Med Food. 2008;11:275–281.
   PubMed Web of Science ®Google Scholar
• Debersac P, Heydel JM, Amiot MJ, Goudonnet H, Artur Y, Suschetet M, Siess MH. Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food Chem Toxicol. 2001a;39(9):907–918.
   PubMed Web of Science ®Google Scholar
• Debersac P, Vernevaut MF, Amiot MJ, Suschetet M, Siess MH. Effects of a water-soluble extract of rosemary and its purified component rosmarinic acid on xenobiotic-metabolizing enzymes in rat liver. Food Chem Toxicol. 2001b;39:109–117.
   PubMed Web of Science ®Google Scholar
• del Bano MJ, Lorente J, Castillo J, Benavente-Garcia O, Del Rio JA, Ortuno A, Quirin KW, Gerard D. Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Antioxidant activity. J Agric Food Chem. 2003;51:4247–4253.
   PubMed Web of Science ®Google Scholar
• del Bano MJ, Lorente J, Castillo J, Benavente-Garcia O, Marin MP, Del Rio JA, Ortuno A, Ibarra I. Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Postulation of a biosynthetic pathway. J Agric Food Chem. 2004;52:4987–4992.
   PubMed Web of Science ®Google Scholar
• Del Campo J, Amiot MJ, Nguyen-The C. Antimicrobial effect of rosemary extracts. J Food Prot. 2000;63:1359–1368.
   PubMed Web of Science ®Google Scholar
• Dias PC, Foglio MA, Possenti A, de Carvalho JE. Antiulcerogenic activity of crude hydroalcoholic extract of Rosmarinus officinalis L. J Ethnopharmacol. 2000;69:57–62.
   PubMed Web of Science ®Google Scholar
• Diego MA, Jones NA, Field T, Hernandez-Reif M, Schanberg S, Kuhn C, McAdam V, Galamaga R, Galamaga M. Aromatherapy positively affects mood, EEG patterns of alertness and math computations. Int J Neurosci. 1998;96:217–224.
   PubMed Web of Science ®Google Scholar
• Doolaege EH, Raes K, Smet K, Andjelkovic M, Van Poucke C, De Smet S, Verhe R. Characterization of two unknown compounds in methanol extracts of rosemary oil. J Agric Food Chem. 2007;55:7283–7287.
   PubMed Web of Science ®Google Scholar
• Dorrie J, Sapala K, Zunino SJ. Carnosol-induced apoptosis and downregulation of Bcl-2 in B-lineage leukemia cells. Cancer Lett. 2001;170:33–39.
   PubMed Web of Science ®Google Scholar
• Dragan S, Nicola T, Ilina R, Ursoniu S, Kimar A, Nimade S, Nicola T. Role of multi-component functional foods in the complex treatment of patients with advanced breast cancer. Rev Med Chir Soc Med Nat Iasi. 2007;111:877–884.
   PubMedGoogle Scholar
• Du M, Ahn DU. Effect of antioxidants on the quality of irradiated sausages prepared with turkey thigh meat. Poult Sci. 2002;81:1251–1256.
   PubMedGoogle Scholar
• Durakovic Z, Durakovic S. The effect of rosemary oil on Candida albicans. J Indian Med Assoc. 1979;72:175–176.
   PubMedGoogle Scholar
• Elgayyar M, Draughon FA, Golden DA, Mount JR. Antimicrobial activity of essential oils from plants against selected pathogenic and saprophytic microorganisms. J Food Prot. 2001;64:1019–1024.
   PubMed Web of Science ®Google Scholar
• Englberger W, Hadding U, Etschenberg E, Graf E, Leyck S, Winkelmann J, Parnham MJ. Rosmarinic acid: a new inhibitor of complement C3-convertase with anti-inflammatory activity. Int J Immunopharmacol. 1988;10:729–737.
   PubMed Web of Science ®Google Scholar
• Erdogrul OT. Antibacterial activities of some plant extracts used in folk medicine. Pharm Biol. 2002;40:269–273.
   Web of Science ®Google Scholar
• Erenmemisoglu A, Saraymen R, Ustun S. Effect of a Rosmarinus officinalis leave extract on plasma glucose levels in normoglycaemic and diabetic mice. Pharmazie. 1997;52:645–646.
   PubMedGoogle Scholar
• Erkr F, Erdemir T, Ceylan FO, Toker C. Fumigant toxicity of three essential oils and their binary and tertiary mixtures against the pulse beetle, Callosobruchus maculates F. (Coleoptera: bruchidae). Fresen Environ Bull. 2009;18:975–981.
   Google Scholar
• Esiyok D, Otles S, Akcicek E. Herbs as a food source in Turkey. Asian Pac J Cancer Prev. 2004;5:334–339.
   PubMedGoogle Scholar
• Etter SC. Rosmarinus officinalis as an Antioxidant. J Herbs Spices Med Plants 2004;11:121–159.
   Google Scholar
• Fabio A, Corona A, Forte E, Quaglio P. Inhibitory activity of spices and essential oils on psychrotrophic bacteria. New Microbiol. 2003;26:115–120.
   PubMedGoogle Scholar
• Fahim FA, Esmat AY, Fadel HM, Hassan KF. Allied studies on the effect of Rosmarinus officinalis L. on experimental hepatotoxicity and mutagenesis. Int J Food Sci Nutr. 1999;50:413–427.
   PubMed Web of Science ®Google Scholar
• Fan X, Sommers CH, Sokorai KJ. Ionizing radiation and antioxidants affect volatile sulfur compounds, lipid oxidation, and color of ready-to-eat Turkey bologna. J Agric Food Chem. 2004;52:3509–3515.
   PubMedGoogle Scholar
• Fenner R, Betti AH, Mentz LA, Rates SM. Plants with potential antifungal activity employed in Brazilian folk medicine. Braz J Pharm Sci. 2006;42:369–394.
   Google Scholar
• Fernandez L, Duque S, Sanchez I, Quinones D, Rodriguez F, Garcia-Abujeta JL. Allergic contact dermatitis from rosemary (Rosmarinus officinalis L.). Contact Derm. 1997;37:248–249.
   PubMedGoogle Scholar
• Fernandez-Torres R, Perez-Bernal JL, Bello-Lopez MA, Callejon-Mochon M, Jimenez-Sanchez JC, Guiraum-Perez A. Mineral content and botanical origin of Spanish honeys. Talanta. 2005;65:686–691.
   PubMed Web of Science ®Google Scholar
• Flamini G, Cioni PL, Morelli I, Macchia M, Ceccarini L. Main agronomic-productive characteristics of two ecotypes of Rosmarinus officinalis L. and chemical composition of their essential oils. J Agric Food Chem. 2002;50:3512–3517.
   PubMed Web of Science ®Google Scholar
• Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med. 1980;40:309–319.
   PubMed Web of Science ®Google Scholar
• Frackowiak A, Fiszer-Kuc M, Maliszewska I, Bruziewicz-Mikla-Szewska B, Gancarz R. Attempt of using extracts of plants helpful in treatment of oral disease –Halitosi. Herba Polonica. 2003;49:371–372.
   Google Scholar
• Fu Y, Zu Y, Chen L, Efferth T, Liang H, Liu Z, Liu W. Investigation of antibacterial activity of rosemary essential oil against Propionibacterium acnes with atomic force microscopy. Planta Med. 2007a;73:1275–1280.
   PubMedGoogle Scholar
• Fu Y, Zu Y, Chen L, Shi X, Wang Z, Sun S, Efferth T. Antimicrobial activity of clove and rosemary essential oils alone and in combination. Phytother Res. 2007b;21:989–994.
   PubMed Web of Science ®Google Scholar
• Fuchs SM, Schliemann-Willers S, Fischer TW, Elsner P. Protective effects of different marigold (Calendula officinalis L.) and rosemary cream preparations against sodium-lauryl-sulfate-induced irritant contact dermatitis. Skin Pharmacol Physiol. 2005;18:195–200.
   PubMedGoogle Scholar
• Fuhrman B, Volkova N, Rosenblat M, Aviram M. Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic. Antioxid Redox Signal. 2000;2:491–506.
   PubMed Web of Science ®Google Scholar
• Galobart J, Barroeta AC, Baucells MD, Codony R, Ternes W. Effect of dietary supplementation with rosemary extract and alpha-tocopheryl acetate on lipid oxidation in eggs enriched with omega3-fatty acids. Poult Sci. 2001;80:460–467.
   PubMed Web of Science ®Google Scholar
• Ganeva Y, Tsankova E, Simova S, Apostolova B, Zaharieva E. Rofficerone: a new triterpenoid from Rosmarinus officinalis. Planta Med. 1993;59:276–277.
   PubMed Web of Science ®Google Scholar
• Garcia S, Dos Santos EP, Da Salva AJ, Di Giacomo CG, Soares HC. Application of rosemary extracts as sunscreen. Rev Bras Farm. 1992;73:35–36.
   Google Scholar
• Gedney JJ, Glover TL, Fillingim RB. Sensory and affective pain discrimination after inhalation of essential oils. Psychosom Med. 2004;66:599–606.
   PubMedGoogle Scholar
• Geoffroy M, Lambelet P, Richert P. Radical intermediates and antioxidants: an ESR study of radicals formed on carnosic acid in the presence of oxidized lipids. Free Radic Res. 1994;21:247–258.
   PubMed Web of Science ®Google Scholar
• Giachetti D, Taddei E, Taddei I. Pharmacological activity of Mentha piperita, Salvia officinalis and Rosmarinus officinalis essences on Oddi's sphincter. Planta Med. 1986;52:543–544.
   Google Scholar
• Gillij YG, Gleiser RM, Zygadlo JA. Mosquito repellent activity of essential oils of aromatic plants growing in Argentina. Bioresour Technol. 2008;99:2507–2515.
   PubMed Web of Science ®Google Scholar
• Giordani R, Regli P, Kaloustian J, Mikail C, Abou L, Portugal H. Antifungal effect of various essential oils against Candida albicans. Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris. Phytother Res. 2004;18:990–995.
   PubMed Web of Science ®Google Scholar
• Giron LM, Freire V, Alonzo A, Caceres A. Ethnobotanical survey of the medicinal flora used by the Caribs of Guatemala. J Ethnopharmacol. 1991;34:173–187.
   PubMed Web of Science ®Google Scholar
• Gladine C, Rock E, Morand C, Bauchart D, Durand D. Bioavailability and antioxidant capacity of plant extracts rich in polyphenols, given as a single acute dose, in sheep made highly susceptible to lipoperoxidation. Br J Nutr. 2007;98:691–701.
   PubMed Web of Science ®Google Scholar
• Gobert M, Martin B, Ferlay A, Chilliard Y, Graulet B, Pradel P, Bauchart D, Durand D. Plant polyphenols associated with vitamin E can reduce plasma lipoperoxidation in dairy cows given N-3 polyunsaturated fatty acids. J Dairy Sci. 2009;92:6095–6104.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Miret ML, Terrab A, Hernanz D, Fernandez-Recamales MA, Heredia FJ. Multivariate correlation between color and mineral composition of honeys and by their botanical origin. J Agric Food Chem. 2005;53:2574–2580.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Trujano ME, Pena EI, Martinez AL, Moreno J, Guevara-Fefer P, Deciga-Campos M, Lopez-Munoz FJ. Evaluation of the antinociceptive effect of Rosmarinus officinalis L. using three different experimental models in rodents. J Ethnopharmacol. 2007;111:476–482.
   PubMed Web of Science ®Google Scholar
• Grabensteiner E, Arshad N, Hess M. Differences in the in vitro susceptibility of mono-eukaryotic cultures of Histomonas meleagridis, Tetratrichomonas gallinarum, and Blastocystis sp. to natural organic compounds. Parasitol Res. 2007;101:193–199.
   PubMed Web of Science ®Google Scholar
• Gramza-Michalowska A, Korczak J, Regula J. Use of plant extracts in summer and winter seasons butter oxidative stability improvement. Asia Pac J Clin Nutr. 2007;16(Suppl 1):85–88.
   PubMedGoogle Scholar
• Granger R, Passet J, Arbousset G, Girard JP. Biogenetic relations between verbenone and alpha-pinene in Rosmarinus officinalis L. C R Hebd Seances Acad Sci D. 1970;270:209–212.
   PubMedGoogle Scholar
• Grayer RJ, Eckert MR, Veitch NC, Kite GC, Marin PD, Kokubun T, Simmonds MS, Paton AJ. The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae. Phytochemistry. 2003;64:519–528.
   PubMed Web of Science ®Google Scholar
• Greenlee H, Atkinson C, Stanczyk FZ, Lampe JW. A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women. Cancer Epidemiol Biomarkers Prev. 2007;16:1601–1609.
   PubMed Web of Science ®Google Scholar
• Guin JD. Rosemary cheilitis: one to remember. Contact Derm. 2001;45:63.
   PubMedGoogle Scholar
• Gutierrez J, Barry-Ryan C, Bourke P. The antimicrobial efficacy of plant essential oil combinations and interactions with food ingredients. Int J Food Microbiol. 2008a;124:91–97.
   PubMed Web of Science ®Google Scholar
• Gutierrez J, Rodriguez G, Barry-Ryan C, Bourke P. Efficacy of plant essential oils against foodborne pathogens and spoilage bacteria associated with ready-to-eat vegetables: antimicrobial and sensory screening. J Food Prot. 2008b;71:1846–1854.
   PubMed Web of Science ®Google Scholar
• Gutierrez ME, Garcia AF, Africa DM, Sagrista ML, Casado FJ, Mora M. Interaction of tocopherols and phenolic compounds with membrane lipid components: evaluation of their antioxidant activity in a liposomal model system. Life Sci. 2003;72:2337–2360.
   PubMed Web of Science ®Google Scholar
• Gutierrez R, Alvarado JL, Presno M, Perez-Veyna O, Serrano CJ, Yahuaca P. Oxidative stress modulation by Rosmarinus officinalis in CCl(4)-induced liver cirrhosis. Phytother Res. 2010;24:595–601.
   PubMed Web of Science ®Google Scholar
• Haddad PS, Depot M, Settaf A, Chabli A, Cherrah Y. Comparative study on the medicinal plants most recommended by traditional practitioners in Morocco and Canada. J Herbs Spices Med Plants. 2003;10:25–45.
   Google Scholar
• Hafez HM, Hauck R. Efficacy of a herbal product against Histomonas meleagridis after experimental infection of turkey poults. Arch Anim Nutr. 2006;60:436–442.
   PubMed Web of Science ®Google Scholar
• Haloui M, Louedec L, Michel JB, Lyoussi B. Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea. J Ethnopharmacol. 2000;71:465–472.
   PubMed Web of Science ®Google Scholar
• Harach T, Aprikian O, Monnard I, Moulin J, Membrez M, Beolor JC, Raab T, Mace K, Darimont C. Rosemary (Rosmarinus officinalis L.) leaf extract limits weight gain and liver steatosis in mice fed a high-fat diet. Planta Med. 2010;76:566–571.
   PubMed Web of Science ®Google Scholar
• Haraguchi H, Saito T, Okamura N, Yagi A. Inhibition of lipid peroxidation and superoxide generation by diterpenoids from Rosmarinus officinalis. Planta Med. 2009;61:333–336.
   Google Scholar
• Hasani-Ranjbar S, Larijani B, Abdollahi M. A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases. Inflamm Allergy Drug Targets. 2009;8:2–10.
   PubMedGoogle Scholar
• Hay IC, Jamieson M, Ormerod AD. Randomized trial of aromatherapy. Successful treatment for alopecia areata. Arch Dermatol. 1998;134:1349–1352.
   PubMed Web of Science ®Google Scholar
• Heinrich M, Kufer J, Leonti M, Pardo-de-Santayana M. Ethnobotany and ethnopharmacology— interdisciplinary links with the historical sciences. J Ethnopharmacol. 2006;107:157–160.
   PubMedGoogle Scholar
• Hernandez F, Madrid J, Garcia V, Orengo J, Megias MD. Influence of two plant extracts on broilers performance, digestibility, and digestive organ size. Poult Sci. 2004;83:169–174.
   PubMed Web of Science ®Google Scholar
• Herrero M, Arraez-Roman D, Segura A, Kenndler E, Gius B, Raggid MA, Ibanez E, Cifuentes A. Pressurized liquid extraction-capillary electrophoresis-mass spectrometry for the analysis of polar antioxidants in rosemary extracts. J Chromatogr A. 2005;1084:54–62.
   PubMedGoogle Scholar
• Herrero M, Plaza M, Cifuentes A, Ibanez E. Green processes for the extraction of bioactives from Rosemary: chemical and functional characterization via ultra-performance liquid chromatography-tandem mass spectrometry and in-vitro assays. J Chromatogr A. 2010;1217:2512–2520.
   PubMed Web of Science ®Google Scholar
• Hethelyi E, Kaposi P, Domonkos J, Kernoczi Z. GC/MS investigation of the essential oils Rosmarinus officinalis L. Acta Pharm Hung. 2009;57:159–169.
   Google Scholar
• Hjorther AB, Christophersen C, Hausen BM, Menne T. Occupational allergic contact dermatitis from carnosol, a naturally occurring compound present in rosemary. Contact Derm. 1997;37:99–100.
   PubMed Web of Science ®Google Scholar
• Ho CT, Wang M, Wei GJ, Huang TC, Huang MT. Chemistry and antioxidative factors in rosemary and sage. Biofactors. 2000;13:161–166.
   PubMed Web of Science ®Google Scholar
• Ho SC, Tsai TH, Tsai PJ, Lin CC. Protective capacities of certain spices against peroxynitrite-mediated biomolecular damage. Food Chem Toxicol. 2008;46:920–928.
   PubMed Web of Science ®Google Scholar
• Hoefler C, Fleurentin J, Mortier F, Pelt JM, Guillemain J. Comparative choleretic and hepatoprotective properties of young sprouts and total plant extracts of Rosmarinus officinalis in rats. J Ethnopharmacol. 1987;19:133–143.
   PubMed Web of Science ®Google Scholar
• Hosny M, Johnson HA, Ueltschy AK, Rosazza JP. Oxidation, reduction, and methylation of carnosic acid by Nocardia. J Nat Prod. 2002;65:1266–1269.
   PubMed Web of Science ®Google Scholar
• Hosseinzadeh H, Nourbakhsh M. Effect of Rosmarinus officinalis L. aerial parts extract on morphine withdrawal syndrome in mice. Phytother Res. 2003;17:938–941.
   PubMedGoogle Scholar
• Hsieh CL, Peng CH, Chyau CC, Lin YC, Wang HE, Peng RY. Low-density lipoprotein, collagen, and thrombin models reveal that Rosemarinus officinalis L. exhibits potent antiglycative effects. J Agric Food Chem. 2007;55:2884–2891.
   PubMedGoogle Scholar
• Hsu S. Green tea and the skin. J Am Acad Dermatol. 2005;52:1049–1059.
   PubMed Web of Science ®Google Scholar
• Huang HC, Huang CY, Lin-Shiau SY, Lin JK. Ursolic acid inhibits IL-1beta or TNF-alpha-induced C6 glioma invasion through suppressing the association ZIP/p62 with PKC-zeta and downregulating the MMP-9 expression. Mol Carcinog. 2009;48:517–531.
   PubMed Web of Science ®Google Scholar
• Huang MT, Ho CT, Wang ZY, Ferraro T, Lou YR, Stauber K, Ma W, Georgiadis C, Laskin JD, Conney AH. Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. Cancer Res. 1994;54:701–708.
   PubMed Web of Science ®Google Scholar
• Huang SC, Ho CT, Lin-Shiau SY, Lin JK. Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through downregulating nuclear factor-kappa B and c-Jun. Biochem Pharmacol. 2005;69:221–232.
   PubMed Web of Science ®Google Scholar
• Ibanez E, Cifuentes A, Crego AL, Senorans FJ, Cavero S, Reglero G. Combined use of supercritical fluid extraction, micellar electrokinetic chromatography, and reverse phase high-performance liquid chromatography for the analysis of antioxidants from rosemary (Rosmarinus officinalis L.). J Agric Food Chem. 2000;48:4060–4065.
   PubMed Web of Science ®Google Scholar
• Ibanez E, Kubatova A, Senorans FJ, Cavero S, Reglero G, Hawthorne SB. Subcritical water extraction of antioxidant compounds from rosemary plants. J Agric Food Chem. 2003;51:375–382.
   PubMed Web of Science ®Google Scholar
• Inoue K, Takano H, Shiga A, Fujita Y, Makino H, Yanagisawa R, Ichinose T, Kato Y, Yamada T, Yoshikawa T. Effects of volatile constituents of a rosemary extract on allergic airway inflammation related to house dust mite allergen in mice. Int J Mol Med. 2005;16:315–319.
   PubMedGoogle Scholar
• Inui S, Katayama I. Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel. J Dermatol. 2005;32:667–669.
   PubMedGoogle Scholar
• Ismail SA, Dea T, Abd El-Rahman H, Yassien MA, Beuchat LR. Effectiveness of immersion treatments with acids, trisodium phosphate, and herb decoctions in reducing populations of Yarrowia lipolytica and naturally occurring aerobic microorganisms on raw chicken. Int J Food Microbiol. 2001;64:13–19.
   PubMed Web of Science ®Google Scholar
• Isman MB, Wilson JA, Bradbury R. Insecticidal activities of commercial rosemary oils (Rosmarinus officinalis) against larvae of Pseudaletia unipuncta and Trichoplusia ni in relation to their chemical compositions. Pharm Biol. 2008;46:82–87.
   Web of Science ®Google Scholar
• Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996;17(1):1–12.
   PubMedGoogle Scholar
• Jager S, Trojan H, Kopp T, Laszczyk MN, Scheffler A. Pentacyclic triterpene distribution in various plants –rich sources for a new group of multi-potent plant extracts. Molecules. 2009;14:2016–2031.
   PubMed Web of Science ®Google Scholar
• Jaswir I, Che Man YB, Hassan TH. Performance of phytochemical antioxidant systems in refined-bleached-deodorized palm olein during frying. Asia Pac J Clin Nutr. 2005;14:402–413.
   PubMedGoogle Scholar
• Jimenez MM, Fresno Contreras MJ, Selles E. Pharmacotechnical characterization and effectiveness testing of a proposed emulsion for the treatment of dry skin. Boll Chim Farm. 2002;141: 333–342.
   PubMedGoogle Scholar
• Jirovetz L, Buchbauer G, Denkova Z, Stoyanova A, Murgov I, Schmidt E, Geissler M. Antimicrobial testings and gas chromatographic analysis of pure oxygenated monoterpenes 1,8-cineole, α-terpineol, terpinen-4-ol and camphor as well as target compounds in essential oils of pine (Pinus pinaster), rosemary (Rosmarinus officinalis), tea tree (Melaleuca alternifolia). Sci Pharm. 2005;73:27–38.
   Google Scholar
• Johnson BM, Bolton JL, van Breemen RB. Screening botanical extracts for quinoid metabolites. Chem Res Toxicol. 2001;14:1546–1551.
   PubMedGoogle Scholar
• Jozsa LG. Histologic diagnoses of tissues from two nineteenth-century Habsburgs. Paleopathol Newsl. 2008;141:12–18.
   Google Scholar
• Kahkonen MP, Hopia AI, Vuorela HJ, Rauha JP, Pihlaja K, Kujala TS, Heinonen M. Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem. 1999;47:3954–3962.
   PubMed Web of Science ®Google Scholar
• Kaliora AC, Andrikopoulos NK. Effect of Alkanna albugam root on LDL oxidation. A comparative study with species of the Lamiaceae family. Phytother Res. 2005;19:1077–1079.
   PubMedGoogle Scholar
• Karamarkovic AR, Djuranovic SP, Popovic NP, Bumbasirevic VD, Sijacki AD, Blazic IV. Hepatic abscess secondary to a rosemary twig migrating from the stomach into the liver. World J Gastroenterol. 2007;13:5530–5532.
   PubMedGoogle Scholar
• Karanika MS, Komaitis M, Aggelis G. Effect of aqueous extracts of some plants of Lamiaceae family on the growth of Yarrowia lipolytica. Int J Food Microbiol. 2001;64:175–181.
   PubMedGoogle Scholar
• Karlsen J, Svendsen AB. Composition of etheric oil in the leaves of Rosmarinus officinalis L. 1. Monoterpenchydrocarbons. Terpenes and related materials VI. Planta Med. 1968;16:95–98.
   PubMedGoogle Scholar
• Karpinska M, Borowski J, Danowska-Oziewicz M. Antioxidative activity of rosemary extract in lipid fraction of minced meat balls during storage in a freezer. Nahrung 2000;44:38–41.
   PubMedGoogle Scholar
• Karpinska-Tymoszczyk M. Effect of the addition of ground rosemary on the quality and shelf-life of turkey meatballs during refrigerated storage. Br Poult Sci. 2008;49:742–750.
   PubMed Web of Science ®Google Scholar
• Katerinopoulos HE, Pagona G, Afratis A, Stratigakis N, Roditakis N. Composition and insect attracting activity of the essential oil of Rosmarinus officinalis. J Chem Ecol. 2005;31:111–122.
   PubMed Web of Science ®Google Scholar
• Kaziulin AN, Petukhov AB, Kucheriavyi I. Efficiency of includes of bioactive substances in diet of patient with hepatic encephalopathy. Vopr Pitan. 2006;75:40–44.
   PubMedGoogle Scholar
• Keokamnerd T, Acton JC, Han IY, Dawson PL. Effect of commercial rosemary oleoresin preparations on ground chicken thigh meat quality packaged in a high-oxygen atmosphere. Poult Sci. 2008;87:170–179.
   PubMed Web of Science ®Google Scholar
• Khater HF, Ramadan MY, El Madawy RS. Lousicidal, ovicidal, and repellent efficacy of some essential oils against lice and flies infesting water buffaloes in Egypt. Vet Parasitol. 2009;164:257–266.
   PubMed Web of Science ®Google Scholar
• Kim HY, Kim K. Protein glycation inhibitory and antioxidative activities of some plant extracts in vitro. J Agric Food Chem. 2003;51:1586–1591.
   PubMed Web of Science ®Google Scholar
• Kim MA, Sakong JK, Kim EJ, Kim EH, Kim EH. Effect of aromatherapy massage for the relief of constipation in the elderly. Taehan Kanho Hakhoe Chi. 2005a;35:56–64.
   PubMedGoogle Scholar
• Kim MJ, Nam ES, Paik SI. The effects of aromatherapy on pain, depression, and life satisfaction of arthritis patients. Taehan Kanho Hakhoe Chi. 2005b;35:186–194.
   PubMedGoogle Scholar
• Kim SJ, Han D, Moon KD, Rhee JS. Measurement of superoxide dismutase-like activity of natural antioxidants. Biosci Biotechnol Biochem. 1995;59:822–826.
   PubMed Web of Science ®Google Scholar
• Kitano M, Wanibuchi H, Kikuzaki H, Nakatani N, Imaoka S, Funae Y, Hayashi S, Fukushima S. Chemopreventive effects of coumaperine from pepper on the initiation stage of chemical hepatocarcinogenesis in the rat. Jpn J Cancer Res. 2000;91:674–680.
   PubMedGoogle Scholar
• Klancnik A, Guzej B, Kolar MH, Abramovic H, Mozina SS. In vitro antimicrobial and antioxidant activity of commercial rosemary extract formulations. J Food Prot. 2009;72:1744–1752.
   PubMed Web of Science ®Google Scholar
• Kosaka K, Mimura J, Itoh K, Satoh T, Shimojo Y, Kitajima C, Maruyama A, Yamamoto M, Shirasawa T. Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells. J Biochem. 2010;147:73–81.
   PubMed Web of Science ®Google Scholar
• Kosaka K, Yokoi T. Carnosic acid, a component of rosemary (Rosmarinus officinalis L.), promotes synthesis of nerve growth factor in T98G human glioblastoma cells. Biol Pharm Bull. 2003;26:1620–1622.
   PubMed Web of Science ®Google Scholar
• Kovar KA, Gropper B, Friess D, Ammon HP. Blood levels of 1, 8-cineole and locomotor activity of mice after inhalation and oral administration of rosemary oil. Planta Med. 1987;53:315–318.
   PubMed Web of Science ®Google Scholar
• Kreis P, Dietrich A, Mosandl A. Chiral compounds of essential oils. Part 18. On the authenticity of assessment of the essential oil of Rosmarinus officinalis L. Die Pharmazie. 1994;49:761–765.
   Web of Science ®Google Scholar
• Kuhlmann A, Rohl C. Phenolic antioxidant compounds produced by in vitro cultures of rosemary (Rosmarinus officinalis) and their anti-inflammatory effect on lipopolysaccharide-activated microglia. Pharm Biol. 2006;44:401–410.
   Web of Science ®Google Scholar
• Kwon YI, Vattem DA, Shetty K. Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension. Asia Pac J Clin Nutr. 2006;15:107–118.
   PubMed Web of Science ®Google Scholar
• Lai CS, Lee JH, Ho CT, Liu CB, Wang JM, Wang YJ, Pan MH. Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3, and C/EBP signaling pathways. J Agric Food Chem. 2009;57:10990–10998.
   PubMed Web of Science ®Google Scholar
• Lai PK, Roy J. Antimicrobial and chemopreventive properties of herbs and spices. Curr Med Chem. 2004;11:1451–1460.
   PubMed Web of Science ®Google Scholar
• Laitinen LA, Tammela PS, Galkin A, Vuorela HJ, Marvola ML, Vuorela PM. Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers. Pharm Res. 2004;21:1904–1916.
   PubMed Web of Science ®Google Scholar
• Lamaison JL, Petitjean-Freytet C, Carnat A. Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv. 1991;66:185–188.
   PubMedGoogle Scholar
• Larrondo JV, Agut M, Calvo-Torras MA. Antimicrobial activity of essences from labiates. Microbios. 1995;82:171–172.
   PubMedGoogle Scholar
• Laszczyk MN. Pentacyclic triterpenes of the lupane, oleanane, and ursane group as tools in cancer therapy. Planta Med. 2009;75:1549–1560.
   PubMed Web of Science ®Google Scholar
• Leal PF, Braga ME, Sato DN, Carvalho JE, Marques MO, Meireles MA. Functional properties of spice extracts obtained via supercritical fluid extraction. J Agric Food Chem. 2003;51: 2520–2525.
   PubMed Web of Science ®Google Scholar
• Lee JJ, Jin YR, Lee JH, Yu JY, Han XH, Oh KW, Hong JT, Kim TJ, Yun YP. Antiplatelet activity of carnosic acid, a phenolic diterpene from Rosmarinus officinalis. Planta Med. 2007;73:121–127.
   PubMed Web of Science ®Google Scholar
• Lee KG, Shibamoto T. Determination of antioxidant potential of volatile extracts isolated from various herbs and spices. J Agric Food Chem. 2002;50:4947–4952.
   PubMed Web of Science ®Google Scholar
• Lee SY, Gwon SY, Kim SJ, Moon BK. Inhibitory effect of commercial green tea and rosemary leaf powders on the growth of foodborne pathogens in laboratory media and oriental-style rice cakes. J Food Prot. 2009;72:1107–1111.
   PubMedGoogle Scholar
• Lee TG, Williams SK, Sloan D, Littell R. Development and evaluation of a chicken breakfast sausage manufactured with mechanically deboned chicken meat. Poult Sci. 1997;76:415–421.
   PubMed Web of Science ®Google Scholar
• Lemberkovics E, Kery A, Simandi B, Kakasy A, Balazs A, Hethelyi E, Szoke E. Influence of extraction methods on the composition of essential oils. Acta Pharm Hung. 2004;74:166–170.
   PubMedGoogle Scholar
• Lemiere C, Cartier A, Lehrer SB, Malo JL. Occupational asthma caused by aromatic herbs. Allergy. 1996;51:647–649.
   PubMed Web of Science ®Google Scholar
• Lemonica IP, Damasceno DC, di Stasi LC. Study of the embryotoxic effects of an extract of rosemary (Rosmarinus officinalis L.). Braz J Med Biol Res. 1996;29:223–227.
   PubMed Web of Science ®Google Scholar
• Lev E. Drugs held and sold by pharmacists of the Jewish community of medieval (11–14th centuries) Cairo according to lists of materia medica found at the Taylor–Schechter Genizah collection, Cambridge. J Ethnopharmacol. 2007;110:275–293.
   PubMed Web of Science ®Google Scholar
• Llewellyn GC, Burkett ML, Eadie T. Potential mold growth, aflatoxin production, and antimycotic activity of selected natural spices and herbs. J Assoc. Off Anal Chem. 1981;64:955–960.
   PubMedGoogle Scholar
• Lo AH, Liang YC, Lin-Shiau SY, Ho CT, Lin JK. Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through downregulating nuclear factor-kappaB in mouse macrophages. Carcinogenesis. 2002;23:983–991.
   PubMed Web of Science ®Google Scholar
• Lopez P, Sanchez C, Batlle R, Nerin C. Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem. 2005;53:6939–6946.
   PubMed Web of Science ®Google Scholar
• Lopez-Bote CJ, Gray JI, Gomaa EA, Flegal CJ. Effect of dietary administration of oil extracts from rosemary and sage on lipid oxidation in broiler meat. Br Poult Sci. 1998;39:235–240.
   PubMed Web of Science ®Google Scholar
• Lopez-Lazaro M. Distribution and biological activities of the flavonoid luteolin. Mini Rev Med Chem. 2009;9:31–59.
   PubMed Web of Science ®Google Scholar
• Lopez-Munoz F, Alamo C, Garcia-Garcia P. “The herbs that have the property of healing … ,”: the phytotherapy in Don Quixote. J Ethnopharmacol. 2006;106:429–441.
   PubMedGoogle Scholar
• Lopez-Munoz F, Garcia-Garcia P, Alamo C. The virtue of that precious balsam … : approach to Don Quixote from the psychopharmacological perspective. Actas Esp Psiquiatr. 2007;35:149–220.
   PubMedGoogle Scholar
• Lopez-Sebastian S, Ramos E, Ibanez E, Bueno JM, Ballester L, Tabera J, Reglero G. Dearomatization of antioxidant rosemary extracts by treatment with supercritical carbon dioxide. J Agric Food Chem. 1998;46:13–19.
   PubMed Web of Science ®Google Scholar
• Louli V, Ragoussis N, Magoulas K. Recovery of phenolic antioxidants from wine industry by-products. Bioresour Technol. 2004;92:201–208.
   PubMed Web of Science ®Google Scholar
• Luis JC, Martin R, Frias I, Valdes F. Enhanced carnosic acid levels in two rosemary accessions exposed to cold stress conditions. J Agric Food Chem. 2007;55:8062–8066.
   PubMedGoogle Scholar
• Lukaczer D, Darland G, Tripp M, Liska D, Lerman RH, Schiltz B, Bland JS. A pilot trial evaluating Meta050, a proprietary combination of reduced iso-alpha acids, rosemary extract, and oleanolic acid in patients with arthritis and fibromyalgia. Phytother Res. 2005;19:864–869.
   PubMedGoogle Scholar
• Luqman S, Dwivedi GR, Darokar MP, Kalra A, Khanuja SP. Potential of rosemary oil to be used in drug-resistant infections. Altern Ther Health Med. 2007;13:54–59.
   PubMedGoogle Scholar
• Mace K, Offord EA, Harris CC, Pfeifer AM. Development of in vitro models for cellular and molecular studies in toxicology and chemoprevention. Arch Toxicol Suppl. 1998;20:227–236.
   PubMedGoogle Scholar
• Machado DG, Bettio LE, Cunha MP, Capra JC, Dalmarco JB, Pizzolatti MG, Rodrigues AL. Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: involvement of the monoaminergic system. Prog Neuropsychopharmacol Biol Psychiatry 2009;33:642–650.
   PubMed Web of Science ®Google Scholar
• Mahady GB, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother Res. 2005;19:988–991.
   PubMed Web of Science ®Google Scholar
• Mahmoud AA, Al Shihry SS, Son BW. Diterpenoid quinones from rosemary (Rosmarinus officinalis L.). Phytochemistry. 2005;66:1685–1690.
   PubMed Web of Science ®Google Scholar
• Makino T, Ono T, Liu N, Nakamura T, Muso E, Honda G. Suppressive effects of rosmarinic acid on mesangioproliferative glomerulonephritis in rats. Nephron. 2002;92:898–904.
   PubMed Web of Science ®Google Scholar
• Makino T, Ono T, Muso E, Yoshida H, Honda G, Sasayama S. Inhibitory effects of rosmarinic acid on the proliferation of cultured murine mesangial cells. Nephrol Dial Transplant. 2000;15:1140–1145.
   PubMed Web of Science ®Google Scholar
• Mancini DA, Torres RP, Pinto JR, Mancini J. Inhibition of DNA virus: herpes-1 (HSV-1) in cellular culture replication, through an antioxidant treatment extracted from rosemary spice. Braz J Pharm Sci. 2009;45:127–133.
   Web of Science ®Google Scholar
• Mangena T, Muyima NY. Comparative evaluation of the antimicrobial activities of essential oils of Artemisia afra, Pteronia incana, and Rosmarinus officinalis on selected bacteria and yeast strains. Lett Appl Microbiol. 1999;28:291–296.
   PubMed Web of Science ®Google Scholar
• Martin R, Pierrard C, Lejeune F, Hilaire P, Breton L, Bernerd F. Photoprotective effect of a water-soluble extract of Rosmarinus officinalis L. against UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and reconstructed skin. Eur J Dermatol. 2008;18:128–135.
   PubMedGoogle Scholar
• Martinez AL, Gonzalez-Trujano ME, Pellicer F, Lopez-Munoz FJ, Navarrete A. Antinociceptive effect and GC/MS analysis of Rosmarinus officinalis L. essential oil from its aerial parts. Planta Med. 2009;75:508–511.
   PubMed Web of Science ®Google Scholar
• Martinez L, Cilla I, Beltran JA, Roncales P. Combined effect of modified atmosphere packaging and addition of rosemary (Rosmarinus officinalis), ascorbic acid, red beet root (beta vulgaris), and sodium lactate and their mixtures on the stability of fresh pork sausages. J Agric Food Chem. 2006;54:4674–4680.
   PubMed Web of Science ®Google Scholar
• Martinez-Gonzalez MC, Goday Bujan JJ, Martinez GW, Fonseca CE. Concomitant allergic contact dermatitis due to Rosmarinus officinalis (rosemary) and Thymus vulgaris (thyme). Contact Derm. 2007;56:49–50.
   PubMedGoogle Scholar
• Martinez-Tome M, Jimenez AM, Ruggieri S, Frega N, Strabbioli R, Murcia MA. Antioxidant properties of Mediterranean spices compared with common food additives. J Food Prot. 2001;64:1412–1419.
   PubMed Web of Science ®Google Scholar
• Mastelic J, Kustrak D. Essential oil and glycosidically-bound volatiles in aromatic plants. Part 2. Rosemary (Rosmarinus officinalis L., Lamiaceae). Acta Pharmaceutica. 1997;47:139–142.
   Google Scholar
• Masuda T, Inaba Y, Maekawa T, Takeda Y, Tamura H, Yamaguchi H. Recovery mechanism of the antioxidant activity from carnosic acid quinone, an oxidized sage, and rosemary antioxidant. J Agric Food Chem. 2002;50:5863–5869.
   PubMed Web of Science ®Google Scholar
• Masuda T, Inaba Y, Takeda Y. Antioxidant mechanism of carnosic acid: structural identification of two oxidation products. J Agric Food Chem. 2001;49:5560–5565.
   PubMed Web of Science ®Google Scholar
• Masuda T, Kirikihira T, Takeda Y. Recovery of antioxidant activity from carnosol quinone: antioxidants obtained from a water-promoted conversion of carnosol quinone. J Agric Food Chem. 2005;53:6831–6834.
   PubMedGoogle Scholar
• Matsubara S, Shibata H, Ishikawa F, Yokokura T, Takahashi M, Sugimura T, Wakabayashi K. Suppression of Helicobacter pylori-induced gastritis by green tea extract in Mongolian gerbils. Biochem Biophys Res Commun. 2003;310:715–719.
   PubMed Web of Science ®Google Scholar
• Mazzio E, Huber J, Darling S, Harris N, Soliman KF. Effect of antioxidants on L-glutamate and N-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells. Neurotoxicology. 2001;22:283–288.
   PubMedGoogle Scholar
• McCaffrey R, Thomas DJ, Kinzelman AO. The effects of lavender and rosemary essential oils on test-taking anxiety among graduate nursing students. Holist Nurs Pract. 2009;23:88–93.
   PubMedGoogle Scholar
• Milovic I. Medical manuscript of mihail plamenac, a priest. Srp Arh Celok Lek. 1998;126:63–67.
   PubMedGoogle Scholar
• Minich DM, Bland JS, Katke J, Darland G, Hall A, Lerman RH, Lamb J, Carroll B, Tripp M. Clinical safety and efficacy of NG440: a novel combination of rho iso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions. Can J Physiol Pharmacol. 2007;85:872–883.
   PubMedGoogle Scholar
• Minnunni M, Wolleb U, Mueller O, Pfeifer A, Aeschbacher HU. Natural antioxidants as inhibitors of oxygen species-induced mutagenicity. Mutat Res. 1992;269:193–200.
   PubMed Web of Science ®Google Scholar
• Mirshekar R, Dastar B, Shabanpour B. Effect of rosemary, echinacea, green tea extracts and ascorbic acid on broiler meat quality. Pak J Biol Sci. 2009;12:1069–1074.
   PubMedGoogle Scholar
• Miyazawa M, Sugie A, Shimada T. Roles of human CYP2A6 and 2B6 and rat CYP2C11 and 2B1 in the 10-hydroxylation of (-)-verbenone by liver microsomes. Drug Metab Dispos. 2003;31:1049–1053.
   PubMed Web of Science ®Google Scholar
• Miyazawa M, Sugie A, Shindo M. Biotransformation of (-)-verbenone by human liver microsomes. Biosci Biotechnol Biochem. 2002;66:2458–2460.
   PubMed Web of Science ®Google Scholar
• Monino I, Martinez C, Sotomayor JA, Lafuente A, Jordan MJ. Polyphenolic transmission to Segureno lamb meat from ewes’ diet supplemented with the distillate from rosemary (Rosmarinus officinalis) leaves. J Agric Food Chem. 2008;56:3363–3367.
   PubMedGoogle Scholar
• Montes MA, Wilkomirsky T, Valenzuela L, Bello H, Osses F. Essential oils from some Labiatae growing in the Bio-Bio region, Chile, Rosmarinus officinalis L., Mentha pulegium L., Mentha spicata L.: components and antimicrobial activity. Anales de la real Academia de Farmacia. 1991;57:425–438.
   Google Scholar
• Moran AE, Carothers AM, Weyant MJ, Redston M, Bertagnolli MM. Carnosol inhibits beta-catenin tyrosine phosphorylation and prevents adenoma formation in the C57BL/6J/Min/+ (Min/+) mouse. Cancer Res. 2005;65:1097–1104.
   PubMed Web of Science ®Google Scholar
• Moreno S, Scheyer T, Romano CS, Vojnov AA. Antioxidant and antimicrobial activities of rosemary extracts linked to their polyphenol composition. Free Radic. Res. 2006;40:223–231.
   PubMed Web of Science ®Google Scholar
• Moss M, Cook J, Wesnes K, Duckett P. Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults. Int J Neurosci. 2003;113:15–38.
   PubMed Web of Science ®Google Scholar
• Muhlbauer RC, Lozano A, Palacio S, Reinli A, Felix R. Common herbs, essential oils, and monoterpenes potently modulate bone metabolism. Bone. 2003;32:372–380.
   PubMed Web of Science ®Google Scholar
• Munne-Bosch S, Alegre L. Changes in carotenoids, tocopherols, and diterpenes during drought and recovery, and the biological significance of chlorophyll loss in Rosmarinus officinalis plants. Planta. 2000;210:925–931.
   PubMed Web of Science ®Google Scholar
• Munne-Bosch S, Alegre L. Subcellular compartmentation of the diterpene carnosic acid and its derivatives in the leaves of rosemary. Plant Physiol. 2001;125:1094–1102.
   PubMed Web of Science ®Google Scholar
• Munne-Bosch S, Schwarz K, Alegre L. Enhanced formation of alpha-tocopherol and highly oxidized abietane diterpenes in water-stressed rosemary plants. Plant Physiol. 1999a;121: 1047–1052.
   PubMed Web of Science ®Google Scholar
• Munne-Bosch S, Schwarz K, Alegre L. Response of abietane diterpenes to stress in Rosmarinus officinalis L.: new insights into the function of diterpenes in plants. Free Radic Res. 1999b;31(Suppl):S107–S112.
   Google Scholar
• Nabekura T, Yamaki T, Hiroi T, Ueno K, Kitagawa S. Inhibition of anticancer drug efflux transporter P-glycoprotein by rosemary phytochemicals. Pharmacol Res. 2010;61:259–263.
   PubMed Web of Science ®Google Scholar
• Naemura A, Ura M, Yamashita T, Arai R, Yamamoto J. Long-term intake of rosemary and common thyme herbs inhibits experimental thrombosis without prolongation of bleeding time. Thromb Res. 2009;122:517–522.
   Google Scholar
• Nakatani N. Phenolic antioxidants from herbs and spices. Biofactors. 2000;13:141–146.
   PubMed Web of Science ®Google Scholar
• Negroni M, D'Agostina A, Arnoldi A. Effects of olive, canola, and sunflower oils on the formation of volatiles from the Maillard reaction of lysine with xylose and glucose. J Agric Food Chem. 2001;49:439–445.
   PubMed Web of Science ®Google Scholar
• Nicolato E, Boschi F, Marzola P, Sbarbati A. Secretory response induced by essential oils on airway surface fluid: a pharmacological MRI study. J Ethnopharmacol. 2009;124:630–634.
   PubMedGoogle Scholar
• Nissen LR, Mansson L, Bertelsen G, Huynh-Ba T, Skibsted LH. Protection of dehydrated chicken meat by natural antioxidants as evaluated by electron spin resonance spectrometry. J Agric Food Chem. 2000;48:5548–5556.
   PubMed Web of Science ®Google Scholar
• Nogues S, Munne-Bosch S, Casadesus J, Lopez-Carbonell M, Alegre L. Daily time course of whole-shoot gas exchange rates in two drought-exposed Mediterranean shrubs. Tree Physiol. 2001;21:51–58.
   PubMedGoogle Scholar
• Nolkemper S, Reichling J, Stintzing FC, Carle R, Schnitzler P. Antiviral effect of aqueous extracts from species of the lamiaceae family against herpes simplex virus type 1 and type 2 in vitro. Planta Med. 2006;72:1378–1382.
   PubMed Web of Science ®Google Scholar
• Nozal Nalda MJ, Bernal Yague JL, Diego Calva JC, Martin Gomez MT. Classifying honeys from the Soria Province of Spain via multivariate analysis. Anal Bioanal Chem. 2005;382:311–319.
   PubMed Web of Science ®Google Scholar
• Nusier MK, Bataineh HN, Daradkah HM. Adverse effects of rosemary (Rosmarinus officinalis L.) on reproductive function in adult male rats. Exp Biol Med (Maywood). 2007;232:809–813.
   PubMed Web of Science ®Google Scholar
• Offord EA, Gautier JC, Avanti O, Scaletta C, Runge F, Kramer K, Applegate LA. Photoprotective potential of lycopene, beta-carotene, vitamin E, vitamin C, and carnosic acid in UVA-irradiated human skin fibroblasts. Free Radic Biol Med. 2002;32:1293–1303.
   PubMed Web of Science ®Google Scholar
• Offord EA, Mace K, Avanti O, Pfeifer AM. Mechanisms involved in the chemoprotective effects of rosemary extract studied in human liver and bronchial cells. Cancer Lett. 1997;114:275–281.
   PubMed Web of Science ®Google Scholar
• Offord EA, Mace K, Ruffieux C, Malnoe A, Pfeifer AM. Rosemary components inhibit benzo[a]pyrene-induced genotoxicity in human bronchial cells. Carcinogenesis. 1995;16:2057–2062.
   PubMed Web of Science ®Google Scholar
• Oh HK, Jones MB, Longhurst WM. Comparison of rumen microbial inhibition resulting from various essential oils isolated from relatively unpalatable plant species. Appl Microbiol. 1968;16:39–44.
   PubMedGoogle Scholar
• Okamura N, Haraguchi H, Hashimoto K, Yagi A. Flavonoids in Rosmarinus officinalis leaves. Phytochemistry. 1994;37:1463–1466.
   PubMed Web of Science ®Google Scholar
• Olmos E, Sanchez-Blanco MJ, Ferrandez T, Alarcon JJ. Subcellular effects of drought stress in Rosmarinus officinalis. Plant Biol (Stuttg). 2007;9:77–84.
   PubMed Web of Science ®Google Scholar
• Oluwatuyi M, Kaatz GW, Gibbons S. Antibacterial and resistance modifying activity of Rosmarinus officinalis. Phytochemistry. 2004;65:3249–3254.
   PubMed Web of Science ®Google Scholar
• Ormeno E, Baldy V, Ballini C, Fernandez C. Production and diversity of volatile terpenes from plants on calcareous and siliceous soils: effect of soil nutrients. J Chem Ecol. 2008;34:1219–1229.
   PubMed Web of Science ®Google Scholar
• Ormeno E, Fernandez C, Mevy JP. Plant coexistence alters terpene emission and content of Mediterranean species. Phytochemistry. 2007a;68:840–852.
   PubMed Web of Science ®Google Scholar
• Ormeno E, Mevy JP, Vila B, Bousquet-Melou A, Greff S, Bonin G, Fernandez C. Water-deficit stress induces different monoterpene and sesquiterpene emission changes in Mediterranean species. Relationship between terpene emissions and plant water potential. Chemosphere. 2007b;67: 276–284.
   PubMed Web of Science ®Google Scholar
• Oskay M, Sari D. Antimicrobial screening of some Turkish medicinal plants. Pharm Biol. 2007;45:176–181.
   Web of Science ®Google Scholar
• Ozcan M. Antioxidant activities of rosemary, sage, and sumac extracts and their combinations on stability of natural peanut oil. J Med Food. 2003;6:267–270.
   PubMedGoogle Scholar
• Ozcan M. Effect of spice hydrosols on the growth of Aspergillus parasiticus NRRL 2999 strain. J Med Food. 2005;8:275–278.
   PubMedGoogle Scholar
• Ozcan MM, Chalchat JC. Chemical composition and antifungal activity of rosemary (Rosmarinus officinalis L.) oil from Turkey. Int J Food Sci Nutr. 2008;59:691–698.
   PubMed Web of Science ®Google Scholar
• Panizzi L, Flamini G, Cioni PL, Morelli I. Composition and antimicrobial properties of essential oils of four Mediterranean Lamiaceae. J Ethnopharmacol. 1993;39:167–170.
   PubMed Web of Science ®Google Scholar
• Papageorgiou V, Gardeli C, Mallouchos A, Papaioannou M, Komaitis M. Variation of the chemical profile and antioxidant behavior of Rosmarinus officinalis L. and Salvia Fruticosa Miller grown in Greece. J Agric Food Chem. 2008a;56:7254–7264.
   PubMed Web of Science ®Google Scholar
• Papageorgiou V, Mallouchos A, Komaitis M. Investigation of the antioxidant behavior of air- and freeze-dried aromatic plant materials in relation to their phenolic content and vegetative cycle. J Agric Food Chem. 2008b;56:5743–5752.
   PubMed Web of Science ®Google Scholar
• Parada M, Carrio E, Bonet MA, Valles J. Ethnobotany of the Alt Emporda region (Catalonia, Iberian Peninsula): plants used in human traditional medicine. J Ethnopharmacol. 2009;124:609–618.
   PubMed Web of Science ®Google Scholar
• Paris A, Strukelj B, Renko M, Turk V, Pukl M, Umek A, Korant BD. Inhibitory effect of carnosic acid on HIV-1 protease in cell-free assays [corrected]. J Nat Prod. 1993;56:1426–1430.
   PubMed Web of Science ®Google Scholar
• Park JA, Kim S, Lee SY, Kim CS, Kim DK, Kim SJ, Chun HS. Beneficial effects of carnosic acid on dieldrin-induced dopaminergic neuronal cell death. Neuroreport. 2008;19:1301–1304.
   PubMed Web of Science ®Google Scholar
• Park MK, Lee ES. The effect of aroma inhalation method on stress responses of nursing students. Taehan Kanho Hakhoe Chi. 2004;34:344–351.
   PubMedGoogle Scholar
• Peng CH, Su JD, Chyau CC, Sung TY, Ho SS, Peng CC, Peng RY. Supercritical fluid extracts of rosemary leaves exhibit potent anti-inflammation and anti-tumor effects. Biosci Biotechnol Biochem. 2007;71:2223–2232.
   PubMed Web of Science ®Google Scholar
• Peng Y, Yuan J, Liu F, Ye J. Determination of active components in rosemary by capillary electrophoresis with electrochemical detection. J Pharm Biomed Anal. 2005;39:431–437.
   PubMed Web of Science ®Google Scholar
• Perez-Fons L, Aranda FJ, Guillen J, Villalain J, Micol V. Rosemary (Rosmarinus officinalis) diterpenes affect lipid polymorphism and fluidity in phospholipid membranes. Arch Biochem Biophys. 2006;453:224–236.
   PubMed Web of Science ®Google Scholar
• Perez-Fons L, Garzon MT, Micol V. Relationship between the antioxidant capacity and effect of rosemary (Rosmarinus officinalis L.) polyphenols on membrane phospholipid order. J Agric Food Chem. 2010;58:161–171.
   PubMed Web of Science ®Google Scholar
• Perrucci S, Mancianti F, Cioni PL, Flamini G, Morelli I, Macchioni G. In vitro antifungal activity of essential oils against some isolates of Microsporum canis and Microsporum gypseum. Planta Med. 1994;60:184–187.
   PubMed Web of Science ®Google Scholar
• Persson E, Graziani G, Ferracane R, Fogliano V, Skog K. Influence of antioxidants in virgin olive oil on the formation of heterocyclic amines in fried beefburgers. Food Chem Toxicol. 2003;41:1587–1597.
   PubMed Web of Science ®Google Scholar
• Pertino MW, Schmeda-Hirschmann G. The corrected structure of rosmaridiphenol, a bioactive diterpene from Rosmarinus officinalis. Planta Med. 2010;76:629–632.
   PubMedGoogle Scholar
• Pezo D, Salafranca J, Nerin C. Determination of the antioxidant capacity of active food packagings by in situ gas-phase hydroxyl radical generation and high-performance liquid chromatography-fluorescence detection. J Chromatogr. A 2008;1178:126–133.
   PubMed Web of Science ®Google Scholar
• Plouzek CA, Ciolino HP, Clarke R, Yeh GC. Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract. Eur J Cancer. 1999;35:1541–1545.
   PubMed Web of Science ®Google Scholar
• Poeckel D, Greiner C, Verhoff M, Rau O, Tausch L, Hornig C, Steinhilber D, Schubert-Zsilavecz M, Werz O. Carnosic acid and carnosol potently inhibit human 5-lipoxygenase and suppress pro-inflammatory responses of stimulated human polymorphonuclear leukocytes. Biochem Pharmacol. 2008;76:91–97.
   PubMed Web of Science ®Google Scholar
• Posadas SJ, Caz V, Largo C, De la GB, Matallanas B, Reglero G, De Miguel E. Protective effect of supercritical fluid rosemary extract, Rosmarinus officinalis, on antioxidants of major organs of aged rats. Exp Gerontol. 2009;44:383–389.
   PubMed Web of Science ®Google Scholar
• Pozo-Insfran D, Follo-Martinez A, Talcott ST, Brenes CH. Stability of copigmented anthocyanins and ascorbic acid in muscadine grape juice processed by high hydrostatic pressure. J Food Sci. 2007;72:S247–S253.
   Google Scholar
• Pozzatti P, Scheid LA, Spader TB, Atayde ML, Santurio JM, Alves SH. In vitro activity of essential oils extracted from plants used as spices against fluconazole-resistant and fluconazole-susceptible Candida spp. Can J Microbiol. 2008;54:950–956.
   PubMed Web of Science ®Google Scholar
• Prat ML, Lopez-Gonzalvez A, Ruiz MA, Barbas C. Ultrasound-assisted extraction for rapid determination of Zn, Cu, Fe, Mg, and Mn in liver of diabetic rats under different antioxidant treatments. J Pharm Biomed Anal. 2009;49:1040–1044.
   PubMedGoogle Scholar
• Presti ML, Ragusa S, Trozzi A, Dugo P, Visinoni F, Fazio A, Dugo G, Mondello L. A comparison between different techniques for the isolation of rosemary essential oil. J Sep Sci. 2005;28:273–280.
   PubMed Web of Science ®Google Scholar
• Proenca da Cunha A, Roque OR. Contribution to the study of the essential oil of Portuguese rosemary. Part 2. Quantitative variations of the main constituents during the spring blooming. Boletim da Faculdade de Farmacia de Coimbra. 1986;10:5–13.
   Google Scholar
• Pukalskas A, van Beek TA, de Waard P. Development of a triple hyphenated HPLC-radical scavenging detection-DAD-SPE-NMR system for the rapid identification of antioxidants in complex plant extracts. J Chromatogr A. 2005;1074:81–88.
   PubMed Web of Science ®Google Scholar
• Putnam SE, Scutt AM, Bicknell K, Priestley CM, Williamson EM. Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health. Phytother Res. 2007;21:99–112.
   PubMed Web of Science ®Google Scholar
• Pyevich D, Bogenschutz MP. Herbal diuretics and lithium toxicity. Am J Psychiatry. 2001;158:1329.
   PubMedGoogle Scholar
• Quave CL, Plano LR, Pantuso T, Bennett BC. Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus. J Ethnopharmacol. 2008;118:418–428.
   PubMed Web of Science ®Google Scholar
• Rababah TM, Hettiarachchy NS, Horax R. Total phenolics and antioxidant activities of fenugreek, green tea, black tea, grape seed, ginger, rosemary, gotu kola, and ginkgo extracts, vitamin E, and tert-butylhydroquinone. J Agric Food Chem. 2004;52:5183–5186.
   PubMed Web of Science ®Google Scholar
• Rakover Y, Ben Arye E, Goldstein LH. The treatment of respiratory ailments with essential oils of some aromatic medicinal plants. Harefuah. 2008;147:783–788, 838.
   PubMedGoogle Scholar
• Ramirez P, Garcia-Risco MR, Santoyo S, Senorans FJ, Ibanez E, Reglero G. Isolation of functional ingredients from rosemary by preparative-supercritical fluid chromatography (Prep-SFC). J Pharm Biomed Anal. 2006;41:1606–1613.
   PubMed Web of Science ®Google Scholar
• Ranger CM, Reding ME, Oliver JB, Moyseenko JJ, Youssef NN. Toxicity of botanical formulations to nursery-infesting white grubs (Coleoptera: scarabaeidae). J Econ Entomol. 2009;102: 304–308.
   PubMedGoogle Scholar
• Rasmussen KE, Rasmussen S, Baerheim SA. Quantitative variations of some components of the foliage volatile oil of Rosmarinus officinalis L. in the spring. Terpenes and related compounds. XIX Pharm Weekbl. 1972;107:309–313.
   PubMedGoogle Scholar
• Rasooli I, Fakoor MH, Yadegarinia D, Gachkar L, Allameh A, Rezaei MB. Antimycotoxigenic characteristics of Rosmarinus officinalis and Trachyspermum copticum L. essential oils. Int J Food Microbiol. 2008a;122:135–139.
   PubMed Web of Science ®Google Scholar
• Rasooli I, Shayegh S, Taghizadeh M, Astaneh SD. Phytotherapeutic prevention of dental biofilm formation. Phytother Res. 2008b;22:1162–1167.
   PubMed Web of Science ®Google Scholar
• Rau O, Wurglics M, Paulke A, Zitzkowski J, Meindl N, Bock A, Dingermann T, Abdel-Tawab M, Schubert-Zsilavecz M. Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated receptor gamma. Planta Med. 2006;72:881–887.
   PubMed Web of Science ®Google Scholar
• Reichling J, Nolkemper S, Stintzing FC, Schnitzler P. Impact of ethanolic lamiaceae extracts on herpesvirus infectivity in cell culture. Forsch Komplementmed. 2008;15:313–320.
   PubMedGoogle Scholar
• Ribeiro A, Arnaud P, Frazao S, Venancio F, Chaumeil JC. Development of vegetable extracts by microencapsulation. J Microencapsul. 1997;14:735–742.
   PubMed Web of Science ®Google Scholar
• Ritschel WA, Starzacher A, Sabouni A, Hussain AS, Koch HP. Percutaneous absorption of rosmarinic acid in the rat. Methods Find Exp Clin Pharmacol. 1989;11:345–352.
   PubMed Web of Science ®Google Scholar
• Rota C, Carraminana JJ, Burillo J, Herrera A. In vitro antimicrobial activity of essential oils from aromatic plants against selected foodborne pathogens. J Food Prot. 2004;67:1252–1256.
   PubMed Web of Science ®Google Scholar
• Rudzinska M, Korczak J, Gramza A, Wasowicz E, Dutta PC. Inhibition of stigmasterol oxidation by antioxidants in purified sunflower oil. J AOAC Int. 2004;87:499–504.
   PubMedGoogle Scholar
• Ruiz Del Castillo ML, Blanch GP. Enantiomeric purity of (+/−) -methyl jasmonate in fresh leaf samples and commercial fragrances. J Sep Sci. 2007;30:2117–2122.
   PubMedGoogle Scholar
• Ruiz A, Williams SK, Djeri N, Hinton A, Jr, Rodrick GE. Nisin, rosemary, and ethylenediaminetetraacetic acid affect the growth of Listeria monocytogenes on ready-to-eat turkey ham stored at four degrees celsius for sixty-three days. Poult Sci. 2009;88:1765–1772.
   PubMed Web of Science ®Google Scholar
• Saenz-Lopez R, Fernandez-Zurbano P, Tena MT. Capillary electrophoretic separation of phenolic diterpenes from rosemary. J Chromatogr A. 2002;953:251–256.
   PubMedGoogle Scholar
• Sagorchev P, Lukanov J, Beer AM. Investigations into the specific effects of rosemary oil at the receptor level. Phytomedicine. 2010;17:693–697.
   PubMedGoogle Scholar
• Saito Y, Shiga A, Yoshida Y, Furuhashi T, Fujita Y, Niki E. Effects of a novel gaseous antioxidative system containing a rosemary extract on the oxidation induced by nitrogen dioxide and ultraviolet radiation. Biosci Biotechnol Biochem. 2009;68:781–786.
   Google Scholar
• Samman S, Sandstrom B, Toft MB, Bukhave K, Jensen M, Sorensen SS, Hansen M. Green tea or rosemary extract added to foods reduces nonheme-iron absorption. Am J Clin Nutr. 2001;73: 607–612.
   PubMed Web of Science ®Google Scholar
• Sancheti G, Goyal P. Modulatory influence of Rosemarinus officinalis on DMBA-induced mouse skin tumorigenesis. Asian Pac J Cancer Prev. 2006a;7:331–335.
   PubMedGoogle Scholar
• Sancheti G, Goyal PK. Effect of Rosmarinus officinalis in modulating 7, 12-dimethyl benz(a)anthracene induced skin tumorigenesis in mice. Phytother Res. 2006b;20:981–986.
   PubMed Web of Science ®Google Scholar
• Sandasi M, Leonard CM, Viljoen AM. The in vitro antibiofilm activity of selected culinary herbs and medicinal plants against Listeria monocytogenes. Lett Appl Microbiol. 2010;50:30–35.
   PubMed Web of Science ®Google Scholar
• Sanders C, Diego M, Fernandez M, Field T, Hernandez-Reif M, Roca A. EEG asymmetry responses to lavender and rosemary aromas in adults and infants. Int J Neurosci. 2002;112:1305–1320.
   PubMed Web of Science ®Google Scholar
• Santos FA, Rao VS. Mast cell involvement in the rat paw oedema response to 1, 8-cineole, the main constituent of eucalyptus and rosemary oils. Eur J Pharmacol. 1997;331:253–258.
   PubMed Web of Science ®Google Scholar
• Santoyo S, Cavero S, Jaime L, Ibanez E, Senorans FJ, Reglero G. Chemical composition and antimicrobial activity of Rosmarinus officinalis L. essential oil obtained via supercritical fluid extraction. J Food Prot. 2005;68:790–795.
   PubMed Web of Science ®Google Scholar
• Sasse A, Colindres P, Brewer MS. Effect of natural and synthetic antioxidants on the oxidative stability of cooked, frozen pork patties. J Food Sci. 2009;74:S30–S35.
   PubMedGoogle Scholar
• Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y, Kitajima C, Cui J, Kamins J, Okamoto S, Izumi M, Shirasawa T, Lipton SA. Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. J Neurochem. 2008;104:1116–1131.
   PubMed Web of Science ®Google Scholar
• Scheckel KA, Degner SC, Romagnolo DF. Rosmarinic acid antagonizes activator protein-1-dependent activation of cyclooxygenase-2 expression in human cancer and nonmalignant cell lines. J Nutr. 2008;138:2098–2105.
   PubMed Web of Science ®Google Scholar
• Schelz Z, Molnar J, Hohmann J. Antimicrobial and antiplasmid activities of essential oils. Fitoterapia. 2006;77:279–285.
   PubMed Web of Science ®Google Scholar
• Schwarz K, Ternes W. Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. I. Determination of phenolic diterpenes with antioxidative activity amongst tocochromanols using HPLC. Z Lebensm Unters Forsch. 1992a;195:95–98.
   PubMedGoogle Scholar
• Schwarz K, Ternes W. Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. II. Isolation of carnosic acid and formation of other phenolic diterpenes. Z Lebensm Unters Forsch. 1992b;195:99–103.
   PubMedGoogle Scholar
• Schwarz K, Ternes W, Schmauderer E. Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. III. Stability of phenolic diterpenes of rosemary extracts under thermal stress as required for technological processes. Z Lebensm Unters Forsch. 1992c;195:104–107.
   PubMedGoogle Scholar
• Schwiertz A, Duttke C, Hild J, Muller HJ. In vitro activity of essential oils on microorganisms isolated from vaginal infections. Int J Aromather. 2006;16:169–174.
   Google Scholar
• Scollard J, Francis GA, O'Beirne D. Effects of essential oil treatment, gas atmosphere, and storage temperature on Listeria monocytogenes in a model vegetable system. J Food Prot. 2009;72:1209–1215.
   PubMed Web of Science ®Google Scholar
• Selmi G. Therapeutic use of rosemary through the centuries. Policlinico Prat. 1967;74:439–441.
   PubMedGoogle Scholar
• Seyfert M, Hunt MC, Mancini RA, Hachmeister KA, Kropf DH, Unruh JA, Loughin TM. Beef quadriceps hot boning and modified-atmosphere packaging influence properties of injection-enhanced beef round muscles. J Anim Sci. 2005;83:686–693.
   PubMed Web of Science ®Google Scholar
• Shabtay A, Sharabani H, Barvish Z, Kafka M, Amichay D, Levy J, Sharoni Y, Uskokovic MR, Studzinski GP, Danilenko M. Synergistic antileukemic activity of carnosic acid-rich rosemary extract and the 19-nor Gemini vitamin D analogue in a mouse model of systemic acute myeloid leukemia. Oncology. 2008;75:203–214.
   PubMed Web of Science ®Google Scholar
• Shahidi F. Antioxidants in food and food antioxidants. Nahrung. 2000;44:158–163.
   PubMedGoogle Scholar
• Sharabani H, Izumchenko E, Wang Q, Kreinin R, Steiner M, Barvish Z, Kafka M, Sharoni Y, Levy J, Uskokovic M, Studzinski GP, Danilenko M. Cooperative antitumor effects of vitamin D3 derivatives and rosemary preparations in a mouse model of myeloid leukemia. Int J Cancer. 2006;118:3012–3021.
   PubMed Web of Science ®Google Scholar
• Shimojo Y, Kosaka K, Noda Y, Shimizu T, Shirasawa T. Effect of rosmarinic acid in motor dysfunction and life span in a mouse model of familial amyotrophic lateral sclerosis. J Neurosci Res. 2010;88:896–904.
   PubMed Web of Science ®Google Scholar
• Shin S. Anti-aspergillus activities of plant essential oils and their combination effects with ketoconazole or amphotericin B. Arch Pharm Res. 2003;26:389–393.
   PubMed Web of Science ®Google Scholar
• Shukla VK, Bhattacharya K. Extending the shelf life of cosmetic products through novel stabilization of exotic butters and oils. SOFW. 2003;129:38–44.
   Google Scholar
• Silva MD, Silva MA, Higino JS, Pereira MS, Carvalho AD. In vitro antimicrobial activity and antiadherence of Rosmarinus officinalis Linn. against oral planktonic bacteria. Rev Bras Farmacogn. 2008;18:236–240.
   Google Scholar
• Singletary K, MacDonald C, Wallig M. Inhibition by rosemary and carnosol of 7, 12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation. Cancer Lett. 1996;104:43–48.
   PubMed Web of Science ®Google Scholar
• Singletary KW. Rosemary extract and carnosol stimulate rat liver glutathione-S-transferase and quinone reductase activities. Cancer Lett. 1996;100:139–144.
   PubMed Web of Science ®Google Scholar
• Singletary KW, Nelshoppen JM. Inhibition of 7, 12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and of in vivo formation of mammary DMBA-DNA adducts by rosemary extract. Cancer Lett. 1991;60:169–175.
   PubMedGoogle Scholar
• Singletary KW, Rokusek JT. Tissue-specific enhancement of xenobiotic detoxification enzymes in mice by dietary rosemary extract. Plant Foods Hum Nutr. 1997;50:47–53.
   PubMed Web of Science ®Google Scholar
• Siurin SA. Effects of essential oil on lipid peroxidation and lipid metabolism in patients with chronic bronchitis. Klin Med (Mosk). 1997;75:43–45.
   PubMedGoogle Scholar
• Slamenova D, Kuboskova K, Horvathova E, Robichova S. Rosemary-stimulated reduction of DNA strand breaks and FPG-sensitive sites in mammalian cells treated with H2O2 or visible light-excited methylene blue. Cancer Lett. 2002;177:145–153.
   PubMed Web of Science ®Google Scholar
• Smet K, Raes K, Huyghebaert G, Haak L, Arnouts S, De Smet S. Lipid and protein oxidation of broiler meat as influenced by dietary natural antioxidant supplementation. Poult Sci. 2008;87:1682–1688.
   PubMed Web of Science ®Google Scholar
• Smith C, Halliwell B, Aruoma OI. Protection by albumin against the pro-oxidant actions of phenolic dietary components. Food Chem Toxicol. 1992;30:483–489.
   PubMed Web of Science ®Google Scholar
• Soler-Rivas C, Marin FR, Santoyo S, Garcia-Risco MR, Senorans FJ, Reglero G. Testing and enhancing the in vitro bioaccessibility and bioavailability of Rosmarinus officinalis extracts with a high level of antioxidant abietanes. J Agric Food Chem. 2010;58:1144–1152.
   PubMedGoogle Scholar
• Sotelo-Felix JI, Martinez-Fong D, Muriel DLT. Protective effect of carnosol on CCl(4)-induced acute liver damage in rats. Eur J Gastroenterol Hepatol. 2002a;14:1001–1006.
   PubMed Web of Science ®Google Scholar
• Sotelo-Felix JI, Martinez-Fong D, Muriel P, Santillan RL, Castillo D, Yahuaca P. Evaluation of the effectiveness of Rosmarinus officinalis (Lamiaceae) in the alleviation of carbon tetrachloride-induced acute hepatotoxicity in the rat. J Ethnopharmacol. 2002b;81:145–154.
   PubMed Web of Science ®Google Scholar
• Soyal D, Jindal A, Singh I, Goyal PK. Modulation of radiation-induced biochemical alterations in mice by rosemary (Rosemarinus officinalis) extract. Phytomedicine. 2007;14:701–705.
   PubMedGoogle Scholar
• Stashenko EE, Puertas MA, Martinez JR. SPME determination of volatile aldehydes for evaluation of in vitro antioxidant activity. Anal Bioanal Chem. 2002;373:70–74.
   PubMed Web of Science ®Google Scholar
• Steiner M, Priel I, Giat J, Levy J, Sharoni Y, Danilenko M. Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1, 25-dihydroxyvitamin D3 and retinoic acid. Nutr Cancer. 2001;41:135–144.
   PubMed Web of Science ®Google Scholar
• Steinmetz MD, Moulin-Traffort J, Regli P. Transmission and scanning electronmicroscopy study of the action of sage and rosemary essential oils and eucalyptol on Candida albicans. Mycoses. 1988;31:40–51.
   PubMedGoogle Scholar
• Steinmetz MD, Vial M, Millet Y. Actions of essential oils of rosemary and certain of its constituents (eucalyptol and camphor) on the cerebral cortex of the rat in vitro. J Toxicol Clin Exp. 1987;7:259–271.
   PubMedGoogle Scholar
• Suhr KI, Nielsen PV. Antifungal activity of essential oils evaluated by two different application techniques against rye bread spoilage fungi. J Appl Microbiol. 2003;94:665–674.
   PubMed Web of Science ®Google Scholar
• Swain AR, Dutton SP, Truswell AS. Salicylates in foods. J Am Diet Assoc. 1985;85:950–960.
   PubMed Web of Science ®Google Scholar
• Szabo MA, Varga GZ, Hohmann J, Schelz Z, Szegedi E, Amaral L, Molnar J. Inhibition of quorum-sensing signals by essential oils. Phytother Res. 2010;24:782–786.
   PubMed Web of Science ®Google Scholar
• Tada M, Ohkanda T, Kurabe J. Syntheses of carnosic acid and carnosol, anti-oxidants in Rosemary, from pisiferic acid, the major constituent of Sawara. Chem Pharm Bull (Tokyo). 2010;58:27–29.
   PubMedGoogle Scholar
• Tahraoui A, El Hilaly J, Israili ZH, Lyoussi B. Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province). J Ethnopharmacol. 2007;110:105–117.
   PubMed Web of Science ®Google Scholar
• Takahashi T, Tabuchi T, Tamaki Y, Kosaka K, Takikawa Y, Satoh T. Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase 2 enzymes and activation of glutathione metabolism. Biochem Biophys Res Commun. 2006;382:549–554.
   Google Scholar
• Takaki I, Bersani-Amado LE, Vendruscolo A, Sartoretto SM, Diniz SP, Bersani-Amado CA, Cuman RK. Anti-inflammatory and antinociceptive effects of Rosmarinus officinalis L. essential oil in experimental animal models. J Med Food. 2008;11:741–746.
   PubMed Web of Science ®Google Scholar
• Talcott ST, Brenes CH, Pires DM, Pozo-Insfran D. Phytochemical stability and color retention of copigmented and processed muscadine grape juice. J Agric Food Chem. 2003;51:957–963.
   PubMed Web of Science ®Google Scholar
• Tamaki Y, Tabuchi T, Takahashi T, Kosaka K, Satoh T. Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells. Planta Med. 2010;76:683–688.
   PubMedGoogle Scholar
• Tantaoui-Elaraki A, Beraoud L. Inhibition of growth and aflatoxin production in Aspergillus parasiticus by essential oils of selected plant materials. J Environ Pathol Toxicol Oncol. 1994;13:67–72.
   PubMedGoogle Scholar
• Tawfiq N, Wanigatunga S, Heaney RK, Musk SR, Williamson G, Fenwick GR. Induction of the anti-carcinogenic enzyme quinone reductase by food extracts using murine hepatoma cells. Eur J Cancer Prev. 1994;3:285–292.
   PubMedGoogle Scholar
• Tayel AA, El Tras WF. Possibility of fighting food borne bacteria by Egyptian folk medicinal herbs and spices extracts. J Egypt Public Health Assoc. 2009;84:21–32.
   PubMedGoogle Scholar
• Thorsen MA, Hildebrandt KS. Quantitative determination of phenolic diterpenes in rosemary extracts. Aspects of accurate quantification. J Chromatogr A. 2003;995:119–125.
   PubMed Web of Science ®Google Scholar
• Topal U, Sasaki M, Goto M, Otles S. Chemical compositions and antioxidant properties of essential oils from nine species of Turkish plants obtained by supercritical carbon dioxide extraction and steam distillation. Int J Food Sci Nutr. 2008;59:619–634.
   PubMed Web of Science ®Google Scholar
• Torre J, Lorenzo MP, Martinez-Alcazar MP, Barbas C. Simple high-performance liquid chromatography method for alpha-tocopherol measurement in Rosmarinus officinalis leaves. New data on alpha-tocopherol content. J Chromatogr A. 2001;919:305–311.
   PubMedGoogle Scholar
• Tovar L, Salafranca J, Sanchez C, Nerin C. Migration studies to assess the safety in use of a new antioxidant active packaging. J Agric Food Chem. 2005;53:5270–5275.
   PubMed Web of Science ®Google Scholar
• Tsai PJ, Tsai TH, Yu CH, Ho SC. Evaluation of NO-suppressing activity of several Mediterranean culinary spices. Food Chem Toxicol. 2007;45:440–447.
   PubMed Web of Science ®Google Scholar
• Valenzuela A, Sanhueza J, Alonso P, Corbari A, Nieto S. Inhibitory action of conventional food-grade natural antioxidants and natural antioxidants of new development on the thermal-induced oxidation of cholesterol. Int J Food Sci Nutr. 2004;55:155–162.
   PubMed Web of Science ®Google Scholar
• Valenzuela A, Sanhueza J, Nieto S. Cholesterol oxidation: health hazard and the role of antioxidants in prevention. Biol Res. 2003;36:291–302.
   PubMed Web of Science ®Google Scholar
• Valero M, Salmeron MC. Antibacterial activity of 11 essential oils against Bacillus cereus in tyndallized carrot broth. Int J Food Microbiol. 2003;85:73–81.
   PubMed Web of Science ®Google Scholar
• van Vuuren SF, Suliman S, Viljoen AM. The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. Lett Appl Microbiol. 2009;48:440–446.
   PubMed Web of Science ®Google Scholar
• Veal L. The potential effectiveness of essential oils as a treatment for headlice, Pediculus humanus capitis. Complement Ther Nurs Midwifery. 1996;2:97–101.
   PubMedGoogle Scholar
• Verluyten J, Leroy F, De Vuyst L. Effects of different spices used in production of fermented sausages on growth of and curvacin A production by Lactobacillus curvatus LTH 1174. Appl Environ Microbiol. 2004;70:4807–4813.
   PubMed Web of Science ®Google Scholar
• Vijayan P, Raghu C, Ashok G, Dhanaraj SA, Suresh B. Antiviral activity of medicinal plants of Nilgiris. Indian J Med Res. 2004;120:24–29.
   PubMed Web of Science ®Google Scholar
• Vitaglione P, Morisco F, Caporaso N, Fogliano V. Dietary antioxidant compounds and liver health. Crit Rev Food Sci Nutr. 2004;44:575–586.
   PubMed Web of Science ®Google Scholar
• Waliwitiya R, Kennedy CJ, Lowenberger CA. Larvicidal and oviposition-altering activity of monoterpenoids, trans-anithole and rosemary oil to the yellow fever mosquito Aedes aegypti (Diptera: culicidae). Pest Manag Sci. 2009;65:241–248.
   PubMed Web of Science ®Google Scholar
• Wang LH, Wang CC, Kuo SC. Vehicle and enhancer effects on human skin penetration of aminophylline from cream formulations: evaluation in vivo. J Cosmet Sci. 2007;58:245–254.
   PubMed Web of Science ®Google Scholar
• Wang R, Li H, Guo G, Li X, Yu X, Li H, Wang J, Liu F, Chen X. Augmentation by carnosic acid of apoptosis in human leukaemia cells induced by arsenic trioxide via upregulation of the tumour suppressor PTEN. J Int Med Res. 2008;36:682–690.
   PubMed Web of Science ®Google Scholar
• Wargovich MJ, Woods C, Hollis DM, Zander ME. Herbals, cancer prevention, and health. J Nutr. 2001;131:3034S–3036S.
   PubMed Web of Science ®Google Scholar
• Watt K, Christofi N, Young R. The detection of antibacterial actions of whole herb tinctures using luminescent Escherichia coli. Phytother Res. 2007;21:1193–1199.
   PubMed Web of Science ®Google Scholar
• Weckesser S, Engel K, Simon-Haarhaus B, Wittmer A, Pelz K, Schempp CM. Screening of plant extracts for antimicrobial activity against bacteria and yeasts with dermatological relevance. Phytomedicine 2007;14:508–516.
   PubMed Web of Science ®Google Scholar
• Wei FX, Liu JX, Wang L, Li HZ, Luo JB. Expression of bcl-2 and bax genes in the liver cancer cell line HepG2 after apoptosis induced by essential oils from Rosmarinus officinalis. Zhong Yao Cai. 2008;31:877–879.
   PubMedGoogle Scholar
• Wellwood CR, Cole RA. Relevance of carnosic acid concentrations to the selection of rosemary, Rosmarinus officinalis (L.), accessions for optimization of antioxidant yield. J Agric Food Chem. 2004;52:6101–6107.
   PubMed Web of Science ®Google Scholar
• Wijeratne SS, Cuppett SL. Potential of rosemary (Rosemarinus officinalis L.) diterpenes in preventing lipid hydroperoxide-mediated oxidative stress in Caco-2 cells. J Agric Food Chem. 2007;55:1193–1199.
   PubMed Web of Science ®Google Scholar
• Winkler V. Bioactive substances: spices as remedies spice of life. OAZ. 2004;58:1242.
   Google Scholar
• Xiao C, Dai H, Liu H, Wang Y, Tang H. Revealing the metabonomic variation of rosemary extracts using 1H NMR spectroscopy and multivariate data analysis. J Agric Food Chem. 2008;56:10142–10153.
   PubMed Web of Science ®Google Scholar
• Yamamoto J, Yamada K, Naemura A, Yamashita T, Arai R. Testing various herbs for antithrombotic effect. Nutrition. 2005;21:580–587.
   PubMed Web of Science ®Google Scholar
• Yang YC, Lee HS, Clark JM, Ahn YJ. Insecticidal activity of plant essential oils against Pediculus humanus capitis (Anoplura: pediculidae). J Med Entomol. 2004;41:699–704.
   PubMed Web of Science ®Google Scholar
• Yarnell E, Abascal K. Botanical medicine for thyroid regulation. Altern Complement Ther. 2006;12:107–112.
   Google Scholar
• Yarnell E, Abascal K. Botanical medicines for headache. Altern Complement Ther. 2007;13:148–152.
   Google Scholar
• Yarnell E, Abascal K. Herbal Support for methicillin-resistant Staphylococcus aureus infections. Altern Complement Ther. 2009;15:189–195.
   Google Scholar
• Yassaa N, Williams J. Analysis of enantiomeric and non-enantiomeric monoterpenes in plant emissions using portable dynamic air sampling/solid-phase microextraction (PDAS-SPME) and chiral gas chromatography/mass spectrometry. Atmos Environ. 2005;39:4875–4884.
   Web of Science ®Google Scholar
• Yesil-Celiktas O, Nartop P, Gurel A, Bedir E, Vardar-Sukan F. Determination of phenolic content and antioxidant activity of extracts obtained from Rosmarinus officinalis' calli. J Plant Physiol. 2007;164:1536–1542.
   PubMed Web of Science ®Google Scholar
• Yu YM, Lin HC, Chang WC. Carnosic acid prevents the migration of human aortic smooth muscle cells by inhibiting the activation and expression of matrix metalloproteinase-9. Br J Nutr. 2008;100:731–738.
   PubMedGoogle Scholar
• Zandi P, Ahmadi L. Antioxidant effect of plant extracts of Labiatae family. J Food Microbiol. 2000;37:436–439.
   Google Scholar
• Zeng HH, Tu PF, Zhou K, Wang H, Wang BH, Lu JF. Antioxidant properties of phenolic diterpenes from Rosmarinus officinalis. Acta Pharmacol Sin. 2001;22:1094–1098.
   PubMedGoogle Scholar
• Zhao BL, Li XJ, He RG, Cheng SJ, Xin WJ. Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals. Cell Biophys. 1989;14:175–185.
   PubMedGoogle Scholar
• Zhu BT, Loder DP, Cai MX, Ho CT, Huang MT, Conney AH. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis. 1998;19:1821–1827.
   PubMed Web of Science ®Google Scholar
• Zimmermann V. Rosemary as a medicinal plant and wonder-drug. A report on the medieval drug monographs. Sudhoffs Arch. 1980;64:351–370.
   PubMedGoogle Scholar
• Zochling S, Murkovic M, Pfannhauser W. Effects of industrially produced flavours with pro- and antioxidative properties on the formation of the heterocyclic amine PhIP in a model system. J Biochem Biophys Methods. 2002;53:37–44.
   PubMedGoogle Scholar
• Zunino SJ, Storms DH. Carnosol delays chemotherapy-induced DNA fragmentation and morphological changes associated with apoptosis in leukemic cells. Nutr Cancer. 2009;61:94–102.
   PubMedGoogle Scholar