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OncoImmunology Volume 12, 2023 - Issue 1
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Original Research

Immunotherapy with IL12 and PD1/CTLA4 inhibition is effective in advanced ovarian cancer and associates with reversal of myeloid cell-induced immunosuppression

Paul G. Pavicic Jr.a Center for Immunotherapy & Precision Immuno-Oncology (CITI), Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USAView further author information
,
Patricia A. Raymana Center for Immunotherapy & Precision Immuno-Oncology (CITI), Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USAView further author information
,
Shadi Swaidania Center for Immunotherapy & Precision Immuno-Oncology (CITI), Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USAView further author information
,
Amit Rupania Center for Immunotherapy & Precision Immuno-Oncology (CITI), Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USAView further author information
,
Vladimir Makarova Center for Immunotherapy & Precision Immuno-Oncology (CITI), Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USAView further author information
,
Charles S. Tannenbaumb Department of Inflammation and Immunity, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, USAView further author information
,
Robert P. Edwardsc Department of Obstetrics, Gynecology and Reproductive Sciences and Magee Women’s Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAView further author information
,
Anda M. Vladc Department of Obstetrics, Gynecology and Reproductive Sciences and Magee Women’s Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAView further author information
,
C. Marcela Diaz-Monteroa Center for Immunotherapy & Precision Immuno-Oncology (CITI), Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USACorrespondence[email protected]
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&
Haider Mahdic Department of Obstetrics, Gynecology and Reproductive Sciences and Magee Women’s Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;d Division of Gynecologic Oncology; Obstetrics, Gynecology and Women’s Health Institute, Cleveland Clinic, Cleveland, OH, USA;e Translational Hematology Oncology Research Department, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA;f Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USACorrespondence[email protected]
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Article: 2198185 | Received 26 Sep 2022, Accepted 29 Mar 2023, Published online: 10 Apr 2023

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