Increased tryptophan, but not increased glucose metabolism, predict resistance of pembrolizumab in stage III/IV melanoma

Jorge D. Oldana Departments of Radiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA;b Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Benjamin C. Gigliob Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Eric Smitha Departments of Radiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA;b Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Weiling Zhaob Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Deeanna M. Bouchardc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USAView further author information

Marija Ivanovica Departments of Radiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA;b Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Yueh Z. Leea Departments of Radiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA;b Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Frances A. Collichioc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USA;d Departments of Medicine, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Michael O. Meyersc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USA;i Departmant of Surgery, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Diana E. Wallackc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USAView further author information

Amber Abernethy-Leinwandb Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Patricia K. Longc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USA;i Departmant of Surgery, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Dimitri G. Trembathe Departments of Pathology And Laboratory Medicine, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Paul B. Googef Departments of Dermatology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Madeline H. Kowalskig Department of Biostatistics, The University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USAView further author information

Anastasia Ivanovag Department of Biostatistics, The University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USAView further author information

Jennifer A. Ezzellh Departments of Cell Biology and Physiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Nana Nikolaishvili-Feinbergc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USAView further author information

Nancy E. Thomasc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USA;f Departments of Dermatology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Terence Z. Wonga Departments of Radiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA;b Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

David W. Ollilac Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USA;i Departmant of Surgery, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USAView further author information

Zibo Lia Departments of Radiology, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USA;b Biomedical Research Imaging Center, UNC-CH,Chapel Hill, NC, USAView further author information

Stergios J. Moschosc Lineberger Comprehensive Cancer Center, UNC-CH, Chapel Hill, NC, USA;d Departments of Medicine, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, NC, USACorrespondence[email protected]

https://orcid.org/0000-0002-8943-0845 View further author information

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Increased tryptophan, but not increased glucose metabolism, predict resistance of pembrolizumab in stage III/IV melanoma

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Increased tryptophan, but not increased glucose metabolism, predict resistance of pembrolizumab in stage III/IV melanoma

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