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OncoImmunology Volume 12, 2023 - Issue 1
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Original Research

Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer

Tatiana V. Kudlinga Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
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James H.A. Clubba Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, FinlandView further author information
,
Santeri Pakolaa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
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Dafne C.A. Quixabeiraa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, FinlandView further author information
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Iris A.K. Lähdeniemic Translational Lung Cancer Research Group, Institute for Molecular Medicine Finland (FIMM), HiLife, University of Helsinki, Helsinki, Finland;d iCAN Digital Precision Cancer Medicine Flagship, Helsinki, FinlandView further author information
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Camilla Heiniöa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
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Victor Ariasa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
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Riikka Havunena Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, FinlandView further author information
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Victor Cervera-Carrascona Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, FinlandView further author information
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Joao M. Santosa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, FinlandView further author information
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Eva Sutinend iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland;e Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;f Department of Pulmonary Medicine, Heart and Lung Center, Helsinki University Hospital, Helsinki, FinlandView further author information
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Jari Räsäneng General Thoracic and Esophageal Surgery, Heart and Lung Center, Helsinki University Hospital and Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
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Kristian Boreniusd iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland;g General Thoracic and Esophageal Surgery, Heart and Lung Center, Helsinki University Hospital and Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
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Mikko I. Mäyränpääh Pathology, University of Helsinki and Helsinki University Hospital (HUSLAB), Helsinki, FinlandView further author information
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Eero Aaltoneni Faculty of Medicine, Medicum, University of Helsinki, Helsinki, FinlandView further author information
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Suvi Sorsaa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, FinlandView further author information
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Otto Hemminkij Comprehensive Cancer Center, Helsinki University Hospital (HUS), Helsinki, Finland;k Department of Urology, Helsinki University Hospital, Helsinki, FinlandView further author information
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Anna Kanervaa Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;j Comprehensive Cancer Center, Helsinki University Hospital (HUS), Helsinki, Finland;l Department of Gynecology and Obstetrics, Helsinki University Hospital, Helsinki, FinlandView further author information
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Emmy W. Verschurenc Translational Lung Cancer Research Group, Institute for Molecular Medicine Finland (FIMM), HiLife, University of Helsinki, Helsinki, Finland;d iCAN Digital Precision Cancer Medicine Flagship, Helsinki, FinlandView further author information
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Ilkka Ilonend iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland;g General Thoracic and Esophageal Surgery, Heart and Lung Center, Helsinki University Hospital and Faculty of Medicine, University of Helsinki, Helsinki, FinlandView further author information
&
Akseli Hemminkia Cancer Gene Therapy Group, Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland;b TILT Biotherapeutics Ltd, Helsinki, Finland;j Comprehensive Cancer Center, Helsinki University Hospital (HUS), Helsinki, FinlandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7103-8530View further author information
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Article: 2241710 | Received 14 Jun 2023, Accepted 24 Jul 2023, Published online: 02 Aug 2023

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