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OncoImmunology
Volume 12, 2023 - Issue 1
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Original research
PD-L1 (CD274) promoter hypomethylation predicts immunotherapy response in metastatic urothelial carcinoma
Niklas Klümpera Department of Urology and Pediatric Urology, University Medical Center Bonn (UKB), Bonn, Germany;b Institute of Experimental Oncology, University Medical Center Bonn (UKB), Bonn, Germany;c Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), GermanyView further author information
, Lennert Wüstc Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;d Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, GermanyView further author information
, Jonas Saalc Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;e Medical Clinic III for Oncology, Hematology, Immune-Oncology and Rheumatology, University Medical Center Bonn (UKB), Bonn, GermanyView further author information
, Damian J. Ralserb Institute of Experimental Oncology, University Medical Center Bonn (UKB), Bonn, Germany;c Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;f Department of Gynaecology and Gynaecological Oncology, University Medical Center Bonn (UKB), Bonn, GermanyView further author information
, Romina Zarblc Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;d Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, GermanyView further author information
, Jonas Jarczykg Department of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, Mannheim, GermanyView further author information
, Johannes Breyerh Department of Urology, Caritas Hospital St. Josef, University of Regensburg, Regensburg, Germany;i Center for Integrated Oncology, Bavarian Center for Cancer Research (Bayerisches Zentrum für Krebsforschung, BZKF), Erlangen, GermanyView further author information
, Danijel Sikici Center for Integrated Oncology, Bavarian Center for Cancer Research (Bayerisches Zentrum für Krebsforschung, BZKF), Erlangen, Germany;j Center for Integrated Oncology, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany;k Department of Urology and Pediatric Urology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyView further author information
, Bernd Wullichi Center for Integrated Oncology, Bavarian Center for Cancer Research (Bayerisches Zentrum für Krebsforschung, BZKF), Erlangen, Germany;j Center for Integrated Oncology, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany;k Department of Urology and Pediatric Urology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyView further author information
, Christian Bolenzl Department of Urology, University Hospital Ulm, Ulm, GermanyView further author information
, Florian Roghmannm Department of Urology, Ruhr-University Bochum, Herne, GermanyView further author information
, Michael Hölzelb Institute of Experimental Oncology, University Medical Center Bonn (UKB), Bonn, Germany;c Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), GermanyView further author information
, Manuel Rittera Department of Urology and Pediatric Urology, University Medical Center Bonn (UKB), Bonn, Germany;c Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), GermanyView further author information
, Sebastian Striethc Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;d Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, GermanyView further author information
, Arndt Hartmanni Center for Integrated Oncology, Bavarian Center for Cancer Research (Bayerisches Zentrum für Krebsforschung, BZKF), Erlangen, Germany;j Center for Integrated Oncology, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany;n Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany;o Comprehensive Cancer Center EMN, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, GermanyView further author information
, Philipp Erbeng Department of Urology and Urosurgery, Medical Faculty Mannheim, University of Heidelberg, Mannheim, GermanyView further author information
, Ralph M. Wirtzp Center for Integrated Oncology, STRATIFYER Molecular Pathology GmbH, Cologne, GermanyView further author information
, Jennifer Landsbergc Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;q Department of Dermatology and Allergy, University Medical Center Bonn (UKB), Bonn, GermanyView further author information
, Dimo Dietrichc Center for Integrated Oncology, Aachen/Bonn/Cologne/Düsseldorf (CIO-ABCD), Germany;d Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Bonn, GermanyCorrespondence[email protected]
https://orcid.org/0000-0001-9794-7927View further author information
& https://orcid.org/0000-0001-9794-7927View further author information
Markus Ecksteini Center for Integrated Oncology, Bavarian Center for Cancer Research (Bayerisches Zentrum für Krebsforschung, BZKF), Erlangen, Germany;j Center for Integrated Oncology, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany;n Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany;o Comprehensive Cancer Center EMN, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, GermanyView further author information
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Article: 2267744
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Received 17 Aug 2023, Accepted 03 Oct 2023, Published online: 19 Oct 2023
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