International Journal of Chronic Obstructive Pulmonary Disease, Volume 14, Issue (2019)

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International Journal of Chronic Obstructive Pulmonary Disease, Volume 14, Issue (2019)

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Corrigendum

Correction
Nasal high-flow in acute hypercapnic exacerbation of COPD [Corrigendum]
Page: mmclxxiii
Published online: 19 Sep 2019
CitationforNasal high-flow in acute hypercapnic exacerbation of COPD [Corrigendum] | Full Text | PDF (148.1 KB) | EPUB
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Open Access

Clinical Trial Report

Article
Disease awareness in patients with COPD: measurement and extent
Ilaria Baiardini, Paola Rogliani, Pierachille Santus, Angelo G Corsico, Marco Contoli, Nicola Scichilone, Fabiano Di Marco, Patrizia Lessi, Carla Scognamillo, Giorgia Molinengo, Fabio Ferri, Vincenzo Patella, Giuseppe Fiorentino, Mauro Carone & Fulvio Braido
Pages: 1-11
Published online: 17 Dec 2018
AbstractforDisease awareness in patients with COPD: measurement and extent | Full Text | References | PDF (523.5 KB) | EPUB
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Open Access

Original Research

Article
Emphysema extent on computed tomography is a highly specific index in diagnosing persistent airflow limitation: a real-world study in China
Ting Cheng, Yong Li, Shuai Pang, Huan Ying Wan, Guo Chao Shi, Qi Jian Cheng, Qing Yun Li, Zi Lai Pan & Shao Guang Huang
Pages: 13-26
Published online: 17 Dec 2018
AbstractforEmphysema extent on computed tomography is a highly specific index in diagnosing persistent airflow limitation: a real-world study in China | Full Text | References | PDF (1 MB) | EPUB
  • 74 Views
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Open Access
Article
Efficacy and safety of a novel, nebulized glycopyrrolate for the treatment of COPD: effect of baseline disease severity and age; pooled analysis of GOLDEN 3 and GOLDEN 4
Jill Ohar, Robert Tosiello, Thomas Goodin & Shahin Sanjar
Pages: 27-37
Published online: 18 Dec 2018
AbstractforEfficacy and safety of a novel, nebulized glycopyrrolate for the treatment of COPD: effect of baseline disease severity and age; pooled analysis of GOLDEN 3 and GOLDEN 4 | Full Text | References | PDF (608.3 KB) | EPUB
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Open Access
Article
Upper-extremity function prospectively predicts adverse discharge and all-cause COPD readmissions: a pilot study
Hossein Ehsani, Martha Jane Mohler, Todd Golden & Nima Toosizadeh
Pages: 39-49
Published online: 18 Dec 2018
AbstractforUpper-extremity function prospectively predicts adverse discharge and all-cause COPD readmissions: a pilot study | Full Text | References | PDF (758.4 KB) | EPUB
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Open Access
Article
COPD treatment pathways in France: a retrospective analysis of electronic medical record data from general practitioners
Wilhelmine Meeraus, Robert Wood, Rafal Jakubanis, Tim Holbrook, Geoffray Bizouard, Johanna Despres, Camille Correia Da Silva, Gaelle Nachbaur, Sarah H Landis, Yogesh Punekar, Bernard Aguilaniu & Afisi S Ismaila
Pages: 51-63
Published online: 18 Dec 2018
AbstractforCOPD treatment pathways in France: a retrospective analysis of electronic medical record data from general practitioners | Full Text | References | PDF (455.5 KB) | EPUB
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Open Access
Article
Strain measurement on four-dimensional dynamic-ventilation CT: quantitative analysis of abnormal respiratory deformation of the lung in COPD
Yanyan Xu, Tsuneo Yamashiro, Hiroshi Moriya, Maho Tsubakimoto, Yukihiro Nagatani, Shin Matsuoka, Sadayuki Murayama & On behalf of ACTIve Study Group
Pages: 65-72
Published online: 18 Dec 2018
AbstractforStrain measurement on four-dimensional dynamic-ventilation CT: quantitative analysis of abnormal respiratory deformation of the lung in COPD | Full Text | References | PDF (739 KB) | EPUB
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Open Access
Article
Short-term treatment of irbesartan and hydrochlorothiazide decreases plasma N-terminal pro-brain natriuretic peptide levels in subjects with acute exacerbations of COPD
Gui-yun Jiang, Qun Li & Yun-xiang Lv
Pages: 73-80
Published online: 20 Dec 2018
AbstractforShort-term treatment of irbesartan and hydrochlorothiazide decreases plasma N-terminal pro-brain natriuretic peptide levels in subjects with acute exacerbations of COPD | Full Text | References | PDF (351.9 KB) | EPUB
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Open Access
Article
Cigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages
Lu Zhou, Yanqing Le, Jieyu Tian, Xia Yang, Rong Jin, Xiaoyan Gai & Yongchang Sun
Pages: 81-91
Published online: 20 Dec 2018
AbstractforCigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages | Full Text | References | PDF (3.5 MB) | EPUB
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Open Access
Article
Effects of community-based pulmonary rehabilitation in 33 municipalities in Denmark – results from the KOALA project
Nina Godtfredsen, Tina Brandt Sørensen, Marie Lavesen, Birthe Pors, Lone Sander Dalsgaard, Jens Dollerup & Ove Grann
Pages: 93-100
Published online: 21 Dec 2018
AbstractforEffects of community-based pulmonary rehabilitation in 33 municipalities in Denmark – results from the KOALA project | Full Text | References | PDF (333.7 KB) | EPUB
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Open Access
Article
Differences in health care outcomes between postdischarge COPD patients treated with inhaled corticosteroid/long-acting β2-agonist via dry-powder inhalers and pressurized metered-dose inhalers
Eric T Wittbrodt, Lauren A Millette, Kristin A Evans, Machaon Bonafede, Joseph Tkacz & Gary T Ferguson
Pages: 101-114
Published online: 24 Dec 2018
AbstractforDifferences in health care outcomes between postdischarge COPD patients treated with inhaled corticosteroid/long-acting β2-agonist via dry-powder inhalers and pressurized metered-dose inhalers | Full Text | References | PDF (648.4 KB) | EPUB
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Open Access

Corrigendum

Correction
Joint statement for the diagnosis, management, and prevention of chronic obstructive pulmonary disease for Gulf Cooperation Council countries and Middle East-North Africa region, 2017 [Corrigendum]
Page: 115
Published online: 18 Jan 2019
CitationforJoint statement for the diagnosis, management, and prevention of chronic obstructive pulmonary disease for Gulf Cooperation Council countries and Middle East-North Africa region, 2017 [Corrigendum] | Full Text | PDF (102.2 KB) | EPUB
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Open Access

Original Research

Article
Long-term safety and efficacy of formoterol fumarate inhalation solution in patients with moderate-to-severe COPD
Nicola A Hanania, Sanjay Sethi, Arkady Koltun, Jonathan K Ward, Jacqui Spanton & Dik Ng
Pages: 117-127
Published online: 27 Dec 2018
AbstractforLong-term safety and efficacy of formoterol fumarate inhalation solution in patients with moderate-to-severe COPD | Full Text | References | PDF (503.3 KB) | EPUB
  • 92 Views
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Open Access
Article
Reduction in exacerbation of COPD in patients of advanced age using the Japanese Kampo medicine Dai-kenchu-to: a retrospective cohort study
Taisuke Jo, Nobuaki Michihata, Hayato Yamana, Yusuke Sasabuchi, Hiroki Matsui, Hirokazu Urushiyama, Akihisa Mitani, Yasuhiro Yamauchi, Kiyohide Fushimi, Takahide Nagase & Hideo Yasunaga
Pages: 129-139
Published online: 27 Dec 2018
AbstractforReduction in exacerbation of COPD in patients of advanced age using the Japanese Kampo medicine Dai-kenchu-to: a retrospective cohort study | Full Text | References | PDF (480.8 KB) | EPUB
  • 83 Views
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Open Access
Article
The relationship between steps of 6MWT and COPD severity: a cross-sectional study
Guan-Sheng Zeng, Li-Chang Chen, Hui-Zhen Fan, Ling-Ling Wu, Xi-Ping Wu, Ze-Kui Fang, Xi He & Hua-Peng Yu
Pages: 141-148
Published online: 28 Dec 2018
AbstractforThe relationship between steps of 6MWT and COPD severity: a cross-sectional study | Full Text | References | PDF (292.6 KB) | EPUB
  • 389 Views
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Open Access

Review

Review Article
Is COPD associated with alterations in hearing? A systematic review and meta-analysis
Arash Bayat, Nader Saki, Soheila Nikakhlagh, Golshan Mirmomeni, Hanieh Raji, Hossein Soleimani & Fakher Rahim
Pages: 149-162
Published online: 28 Dec 2018
AbstractforIs COPD associated with alterations in hearing? A systematic review and meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB
  • 124 Views
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Open Access

Original Research

Article
Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD
Ying-Ying Zeng, Wei-Ping Hu, Yi-Hui Zuo, Xiao-Ru Wang & Jing Zhang
Pages: 163-168
Published online: 03 Jan 2019
AbstractforAltered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD | Full Text | References | PDF (302.8 KB) | EPUB
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Open Access
Article
The association between recent hospitalized COPD exacerbations and adverse outcomes after percutaneous coronary intervention: a nationwide cohort study
Wei-Chieh Lin, Chang-Wen Chen, Chin-Li Lu, Wu-Wei Lai, Min-Hsin Huang, Liang-Miin Tsai, Chung-Yi Li & Chao-Han Lai
Pages: 169-179
Published online: 03 Jan 2019
AbstractforThe association between recent hospitalized COPD exacerbations and adverse outcomes after percutaneous coronary intervention: a nationwide cohort study | Full Text | References | PDF (1.3 MB) | EPUB
  • 124 Views
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Open Access
Article
Effects of baseline symptom burden on treatment response in COPD
Fernando J Martinez, Roger A Abrahams, Gary T Ferguson, Leif Bjermer, Lars Grönke, Florian Voß & Dave Singh
Pages: 181-194
Published online: 04 Jan 2019
AbstractforEffects of baseline symptom burden on treatment response in COPD | Full Text | References | PDF (1.7 MB) | EPUB
  • 81 Views
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Open Access
Article
Rating sputum cell quality in clinical trials for asthma and COPD treatment
Frauke Pedersen, Ulrich M Zissler, Henrik Watz, Klaus F Rabe, Jens M Hohlfeld & Olaf Holz
Pages: 195-198
Published online: 08 Jan 2019
First Page PreviewforRating sputum cell quality in clinical trials for asthma and COPD treatment | Full Text | References | PDF (1.3 MB) | EPUB
  • 62 Views
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Open Access
Article
A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: the DuoSleep study
Sverre Lehmann, Thomas Ringbæk, Anders Løkke, Ludger Grote, Jan Hedner & Eva Lindberg
Pages: 199-210
Published online: 09 Jan 2019
AbstractforA randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: the DuoSleep study | Full Text | References | PDF (448.4 KB) | EPUB
  • 71 Views
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Open Access

Short Report

Brief Report
Is iron deficiency modulating physical activity in COPD?
Clara Martín-Ontiyuelo, Anna Rodó-Pin, Antonio Sancho-Muñoz, Juana María Martinez-Llorens, Mireia Admetlló, Lluis Molina, Joaquim Gea, Esther Barreiro & Diego A Rodríguez Chiaradía
Pages: 211-214
Published online: 11 Jan 2019
AbstractforIs iron deficiency modulating physical activity in COPD? | Full Text | References | PDF (174.2 KB) | EPUB
  • 68 Views
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Open Access

Original Research

Article
Nutritional status, dietary intake, and health-related quality of life in outpatients with COPD
Ha Thanh Nguyen, Peter F Collins, Toby G Pavey, Nhung Viet Nguyen, Tuong Duy Pham & Danielle L Gallegos
Pages: 215-226
Published online: 24 Oct 2022
AbstractforNutritional status, dietary intake, and health-related quality of life in outpatients with COPD | Full Text | References | PDF (354.6 KB) | EPUB
  • 1638 Views
  • 30 CrossRef citations
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Open Access
Article
Cost-effectiveness of physical activity in the management of COPD patients in the UK
Mafalda Ramos, Mark Lamotte, Laetitia Gerlier, Per Svangren, Anna Miquel-Cases & John Haughney
Pages: 227-239
Published online: 15 Jan 2019
AbstractforCost-effectiveness of physical activity in the management of COPD patients in the UK | Full Text | References | PDF (462.2 KB) | EPUB
  • 380 Views
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Open Access

Corrigendum

Correction
Respiratory medication used in COPD patients from seven Latin American countries: the LASSYC study [Corrigendum]
Page: 241
Published online: 18 Jan 2019
CitationforRespiratory medication used in COPD patients from seven Latin American countries: the LASSYC study [Corrigendum] | Full Text | PDF (98.8 KB) | EPUB
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Open Access
Correction
Russian guidelines for the management of COPD: algorithm of pharmacologic treatment [Corrigendum]
Page: 243
Published online: 18 Jan 2019
CitationforRussian guidelines for the management of COPD: algorithm of pharmacologic treatment [Corrigendum] | Full Text | PDF (97.9 KB) | EPUB
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Open Access
Correction
Bronchiectasis in COPD patients: more than a comorbidity? [Corrigendum]
Page: 245
Published online: 18 Jan 2019
CitationforBronchiectasis in COPD patients: more than a comorbidity? [Corrigendum] | Full Text | PDF (97.8 KB) | EPUB
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Open Access
Correction
Chronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research – a consensus document from six scientific societies [Corrigendum]
Page: 247
Published online: 18 Jan 2019
CitationforChronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research – a consensus document from six scientific societies [Corrigendum] | Full Text | PDF (119.1 KB) | EPUB
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Open Access

Original Research

Article
Real-life effectiveness of indacaterol–glycopyrronium after switching from tiotropium or salmeterol/fluticasone therapy in patients with symptomatic COPD: the POWER study
Alan Kaplan, Kenneth R Chapman, Syed M Anees, Irvin Mayers, Driss Rochdi, Michel Djandji, David Préfontaine & Andrew McIvor
Pages: 249-260
Published online: 18 Jan 2019
AbstractforReal-life effectiveness of indacaterol–glycopyrronium after switching from tiotropium or salmeterol/fluticasone therapy in patients with symptomatic COPD: the POWER study | Full Text | References | PDF (1.3 MB) | EPUB
  • 107 Views
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Open Access
Article
Minimal clinically important difference of 3-minute chair rise test and the DIRECT questionnaire after pulmonary rehabilitation in COPD patients
Jonathan Lévesque, Anestis Antoniadis, Pei Zhi Li, Frédéric Herengt, Christophe Brosson, Jean-Marie Grosbois, Alain Bernady, Anthony Bender, Murielle Favre, Antoine Guerder, Pascale Surpas, Thomas Similowski & Bernard Aguilaniu
Pages: 261-269
Published online: 22 Jan 2019
AbstractforMinimal clinically important difference of 3-minute chair rise test and the DIRECT questionnaire after pulmonary rehabilitation in COPD patients | Full Text | References | PDF (325.7 KB) | EPUB
  • 93 Views
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Open Access
Article
Male current smokers have low awareness and optimistic bias about COPD: field survey results about COPD in Korea
Yong Il Hwang, Yong Bum Park, Hyoung Kyu Yoon, Tae-Hyung Kim, Kwang Ha Yoo, Chin Kook Rhee, Joo Hun Park, Seung Hun Jang, Sunghoon Park, Joo-Hee Kim, Jiyoung Park & Ki-Suck Jung
Pages: 271-277
Published online: 21 Jan 2019
AbstractforMale current smokers have low awareness and optimistic bias about COPD: field survey results about COPD in Korea | Full Text | References | PDF (753.3 KB) | EPUB
  • 149 Views
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Open Access
Article
Changes in COPD inhaler prescriptions in the United Kingdom, 2000 to 2016
Chloe I Bloom, SL Elkin & JK Quint
Pages: 279-287
Published online: 24 Oct 2022
AbstractforChanges in COPD inhaler prescriptions in the United Kingdom, 2000 to 2016 | Full Text | References | PDF (595.6 KB) | EPUB
  • 209 Views
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Open Access
Article
Efficacy of a home discharge care bundle after acute exacerbation of COPD
Stéphanie Cousse, André Gillibert, Mathieu Salaün, Luc Thiberville, Antoine Cuvelier & Maxime Patout
Pages: 289-296
Published online: 22 Jan 2019
AbstractforEfficacy of a home discharge care bundle after acute exacerbation of COPD | Full Text | References | PDF (386.1 KB) | EPUB
  • 199 Views
  • 6 CrossRef citations
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Open Access
Article
Short-term effects of ambient air pollution on chronic obstructive pulmonary disease admissions in Beijing, China (2013–2017)
Nannan Gao, Chunhou Li, Jiadong Ji, Yanli Yang, Shaoting Wang, Xinlun Tian & Kai-Feng Xu
Pages: 297-309
Published online: 23 Jan 2019
AbstractforShort-term effects of ambient air pollution on chronic obstructive pulmonary disease admissions in Beijing, China (2013–2017) | Full Text | References | PDF (828.8 KB) | EPUB
  • 197 Views
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Open Access
Article
Phenotyping and outcomes of hospitalized COPD patients using rapid molecular diagnostics on sputum samples
Nawaf M Alotaibi, Virginia Chen, Zsuzsanna Hollander, Jonathon A Leipsic, Cameron J Hague, Darra T Murphy, Mari L DeMarco, JM FitzGerald, Bruce M McManus, Raymond T Ng & Don D Sin
Pages: 311-319
Published online: 24 Oct 2022
AbstractforPhenotyping and outcomes of hospitalized COPD patients using rapid molecular diagnostics on sputum samples | Full Text | References | PDF (742.6 KB) | EPUB
  • 95 Views
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Open Access
Article
Evaluation of plasma antimicrobial peptide LL-37 and nuclear factor-kappaB levels in stable chronic obstructive pulmonary disease
Pelin Uysal, Gonul Simsek, Sinem Durmus, Volkan Sozer, Hulya Aksan, Sibel Yurt, Caglar Cuhadaroglu, Filiz Kosar, Remise Gelisgen & Hafize Uzun
Pages: 321-330
Published online: 25 Jan 2019
AbstractforEvaluation of plasma antimicrobial peptide LL-37 and nuclear factor-kappaB levels in stable chronic obstructive pulmonary disease | Full Text | References | PDF (857.3 KB) | EPUB
  • 94 Views
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Open Access
Article
Greater eosinophil counts at first COPD hospitalization are associated with more readmissions and fewer deaths
Qing Li, Pierre Larivée, Josiane Courteau, Simon Couillard, Thomas G Poder, Nathalie Carrier, Maryse Bélanger & Alain Vanasse
Pages: 331-341
Published online: 30 Jan 2019
AbstractforGreater eosinophil counts at first COPD hospitalization are associated with more readmissions and fewer deaths | Full Text | References | PDF (779.6 KB) | EPUB
  • 98 Views
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Open Access
Article
Medication adherence and persistence in chronic obstructive pulmonary disease patients receiving triple therapy in a USA commercially insured population
Michael Bogart, Richard H Stanford, François Laliberté, Guillaume Germain, Jennifer W Wu & Mei Sheng Duh
Pages: 343-352
Published online: 19 Feb 2019
AbstractforMedication adherence and persistence in chronic obstructive pulmonary disease patients receiving triple therapy in a USA commercially insured population | Full Text | References | PDF (679.5 KB) | EPUB
  • 280 Views
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Open Access
Article
Early management of COPD: where are we now and where do we go from here? A Delphi consensus project
Fabiano Di Marco, Piero Balbo, Francesco de Blasio, Vittorio Cardaci, Nunzio Crimi, Giuseppe Girbino, Girolamo Pelaia, Pietro Pirina, Pietro Roversi, Pierachille Santus, Nicola Scichilone, Alessandro Vatrella, Patrizio Pasqualetti & Mauro Carone
Pages: 353-360
Published online: 04 Feb 2019
AbstractforEarly management of COPD: where are we now and where do we go from here? A Delphi consensus project | Full Text | References | PDF (465.9 KB) | EPUB
  • 153 Views
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Open Access
Article
Longitudinal change of FEV1 and inspiratory capacity: clinical implication and relevance to exacerbation risk in patients with COPD
Yong Suk Jo, Sung Kyoung Kim, Seoung Ju Park, Soo-Jung Um, Yong-Bum Park, Ki Suck Jung, Deog Kyeom Kim & Kwang Ha Yoo
Pages: 361-369
Published online: 04 Feb 2019
AbstractforLongitudinal change of FEV1 and inspiratory capacity: clinical implication and relevance to exacerbation risk in patients with COPD | Full Text | References | PDF (965.1 KB) | EPUB
  • 101 Views
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Open Access
Article
A prospective study of the clinical outcomes and prognosis associated with comorbid COPD in the atrial fibrillation population
Moisés Rodríguez-Mañero, Estrella López-Pardo, Alberto Cordero, Alberto Ruano-Ravina, José Novo-Platas, María Pereira-Vázquez, Álvaro Martínez-Gómez, Javier García-Seara, Jose-Luis Martínez-Sande, Carlos Peña-Gil, Pilar Mazón, Jose María García-Acuña, Luis Valdés-Cuadrado & José Ramón González-Juanatey
Pages: 371-380
Published online: 12 Feb 2019
AbstractforA prospective study of the clinical outcomes and prognosis associated with comorbid COPD in the atrial fibrillation population | Full Text | References | PDF (350.5 KB) | EPUB
  • 150 Views
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Open Access
Article
Quantitative CT assessment of bronchial and vascular alterations in severe precapillary pulmonary hypertension
Florence Coste, Ilyes Benlala, Gaël Dournes, Claire Dromer, Elodie Blanchard, Pierre-Olivier Girodet, Michel Montaudon, Fabien Baldacci, François Picard, Roger Marthan, François Laurent & Patrick Berger
Pages: 381-389
Published online: 11 Feb 2019
AbstractforQuantitative CT assessment of bronchial and vascular alterations in severe precapillary pulmonary hypertension | Full Text | References | PDF (654.2 KB) | EPUB
  • 77 Views
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Open Access

Expert Opinion

Editorial
When to use single-inhaler triple therapy in COPD: a practical approach for primary care health care professionals
S Gaduzo, V McGovern, J Roberts, JE Scullion & D Singh
Pages: 391-401
Published online: 13 Feb 2019
AbstractforWhen to use single-inhaler triple therapy in COPD: a practical approach for primary care health care professionals | Full Text | References | PDF (450.7 KB) | EPUB
  • 334 Views
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Open Access

Original Research

Article
COPD and the risk of mild cognitive impairment and dementia: a cohort study based on the Chinese Longitudinal Health Longevity Survey
Fei Xie & Lixin Xie
Pages: 403-408
Published online: 13 Feb 2019
AbstractforCOPD and the risk of mild cognitive impairment and dementia: a cohort study based on the Chinese Longitudinal Health Longevity Survey | Full Text | References | PDF (245.2 KB) | EPUB
  • 175 Views
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Open Access
Article
Area under the forced expiratory flow-volume loop in spirometry indicates severe hyperinflation in COPD patients
Nilakash Das, Marko Topalovic, Jean-Marie Aerts & Wim Janssens
Pages: 409-418
Published online: 14 Feb 2019
AbstractforArea under the forced expiratory flow-volume loop in spirometry indicates severe hyperinflation in COPD patients | Full Text | References | PDF (964.1 KB) | EPUB
  • 146 Views
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Open Access
Article
24-hour accelerometry in COPD: Exploring physical activity, sedentary behavior, sleep and clinical characteristics
Mark W Orme, Michael C Steiner, Mike D Morgan, Andrew P Kingsnorth, Dale W Esliger, Sally J Singh & Lauren B Sherar
Pages: 419-430
Published online: 18 Feb 2019
Abstractfor24-hour accelerometry in COPD: Exploring physical activity, sedentary behavior, sleep and clinical characteristics | Full Text | References | PDF (482.8 KB) | EPUB
  • 232 Views
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Open Access
Article
No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation
Noriane A Sievi, Malcolm Kohler, Robert Thurnheer, Joerg D Leuppi, Sarosh Irani, Martin Frey, Martin Brutsche, Thomas Brack & Christian F Clarenbach
Pages: 431-437
Published online: 15 Feb 2019
AbstractforNo impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation | Full Text | References | PDF (400 KB) | EPUB
  • 74 Views
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Open Access
Article
Spirometry evaluation to assess performance of a claims-based predictive model identifying patients with undiagnosed COPD
Chad Moretz, Srinivas Annavarapu, Rakesh Luthra, Seth Goldfarb, Andrew Renda, Asif Shaikh & Shuchita Kaila
Pages: 439-446
Published online: 15 Feb 2019
AbstractforSpirometry evaluation to assess performance of a claims-based predictive model identifying patients with undiagnosed COPD | Full Text | References | PDF (326.9 KB) | EPUB
  • 63 Views
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Open Access
Article
Long-term cost-effectiveness of the fixed-dose combination of tiotropium plus olodaterol based on the DYNAGITO trial results
Martine Hoogendoorn, Isaac Corro Ramos, Michael Baldwin, Laura Luciani, Cecile Fabron, Bruno Detournay & Maureen P M H Rutten-van Mölken
Pages: 447-456
Published online: 18 Feb 2019
AbstractforLong-term cost-effectiveness of the fixed-dose combination of tiotropium plus olodaterol based on the DYNAGITO trial results | Full Text | References | PDF (542.8 KB) | EPUB
  • 95 Views
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Open Access

Letter

Letter
Costen’s syndrome and COPD
Bruno Bordoni
Pages: 457-460
Published online: 18 Feb 2019
First Page PreviewforCosten’s syndrome and COPD | Full Text | References | PDF (171.9 KB) | EPUB
  • 57 Views
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Open Access

Original Research

Article
Efficacy and safety of glycopyrrolate in patients with COPD by reversibility: pooled analysis of GEM1 and GEM2 12-week studies
Jill A Ohar, Alyssa Bowling, Thomas Goodin, Barry Price, Ayca Ozol-Godfrey, Sanjay Sharma & Shahin Sanjar
Pages: 461-470
Published online: 19 Feb 2019
AbstractforEfficacy and safety of glycopyrrolate in patients with COPD by reversibility: pooled analysis of GEM1 and GEM2 12-week studies | Full Text | References | PDF (540.1 KB) | EPUB
  • 57 Views
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Open Access
Article
Exacerbations of Chronic Obstructive Pulmonary Disease Tool to assess the efficacy of acute treatment
Hye Sook Choi, Yong Bum Park, Kyeong Cheol Shin, Seung Hun Jang, Kang Hyeon Choe, Young Sam Kim, Sun Young Kyung, Sung Ho Yoon, Ju Sang Kim & Sung Soo Jung
Pages: 471-478
Published online: 25 Feb 2019
AbstractforExacerbations of Chronic Obstructive Pulmonary Disease Tool to assess the efficacy of acute treatment | Full Text | References | PDF (554.9 KB) | EPUB
  • 125 Views
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Open Access
Article
Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT
Anthony D D’Urzo, Dave Singh, James F Donohue, Edward M Kerwin, Anna Ribera, Eduard Molins, Ferran Chuecos, Diana Jarreta & Esther Garcia Gil
Pages: 479-491
Published online: 26 Feb 2019
AbstractforEfficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT | Full Text | References | PDF (707.4 KB) | EPUB
  • 73 Views
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Article
Longitudinal comparison of outcomes in patients with smoking-related asthma-COPD overlap and in non-smoking asthmatics with incomplete reversibility of airway obstruction
Louis-Philippe Boulet, Marie-Eve Boulay, Joanne Milot, Johane Lepage, Lara Bilodeau & François Maltais
Pages: 493-498
Published online: 27 Feb 2019
AbstractforLongitudinal comparison of outcomes in patients with smoking-related asthma-COPD overlap and in non-smoking asthmatics with incomplete reversibility of airway obstruction | Full Text | References | PDF (313 KB) | EPUB
  • 58 Views
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Open Access
Article
Disrupted resting-state spontaneous neural activity in stable COPD
Huizhen Xin, Haijun Li, Honghui Yu, Jingjing Yu, Juan Zhang, Wenjing Wang & Dechang Peng
Pages: 499-508
Published online: 27 Feb 2019
AbstractforDisrupted resting-state spontaneous neural activity in stable COPD | Full Text | References | PDF (918.3 KB) | EPUB
  • 64 Views
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Open Access
Article
Improving usability and maintaining performance: human-factor and aerosol-performance studies evaluating the new reusable Respimat inhaler
Rajiv Dhand, Joachim Eicher, Michaela Hänsel, Ingeborg Jost, Martin Meisenheimer & Herbert Wachtel
Pages: 509-523
Published online: 05 Mar 2019
AbstractforImproving usability and maintaining performance: human-factor and aerosol-performance studies evaluating the new reusable Respimat inhaler | Full Text | References | PDF (3.4 MB) | EPUB
  • 161 Views
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Article
Survival in the Swedish cohort with alpha-1-antitrypsin deficiency, up to the age of 43–45 years
Behrouz Mostafavi, Eeva Piitulainen & Hanan A Tanash
Pages: 525-530
Published online: 28 Feb 2019
AbstractforSurvival in the Swedish cohort with alpha-1-antitrypsin deficiency, up to the age of 43–45 years | Full Text | References | PDF (180.5 KB) | EPUB
  • 102 Views
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Clinical Trial Report

Article
Extrafine triple therapy delays COPD clinically important deterioration vs ICS/LABA, LAMA, or LABA/LAMA
Dave Singh, Leonardo M Fabbri, Stefano Vezzoli, Stefano Petruzzelli & Alberto Papi
Pages: 531-546
Published online: 28 Feb 2019
AbstractforExtrafine triple therapy delays COPD clinically important deterioration vs ICS/LABA, LAMA, or LABA/LAMA | Full Text | References | PDF (3.9 MB) | EPUB
  • 136 Views
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Original Research

Article
COPD patients’ characteristics, usual care, and adherence to guidelines: the Greek UNLOCK study
Ioanna Tsiligianni, Maria Kampouraki, Despo Ierodiakonou, Ioannis Poulonirakis, Polyvios Papadokostakis & On behalf of the Greek UNLOCK team
Pages: 547-556
Published online: 01 Mar 2019
AbstractforCOPD patients’ characteristics, usual care, and adherence to guidelines: the Greek UNLOCK study | Full Text | References | PDF (815.3 KB) | EPUB
  • 280 Views
  • 17 CrossRef citations
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Article
Ultrafine particles in airways: a novel marker of COPD exacerbation risk and inflammatory status
Einat Fireman Klein, Yochai Adir, Amir Krencel, Regina Peri, Bella Vasserman, Elizabeth Fireman & Aharon Kessel
Pages: 557-564
Published online: 24 Oct 2022
AbstractforUltrafine particles in airways: a novel marker of COPD exacerbation risk and inflammatory status | Full Text | References | PDF (387.9 KB) | EPUB
  • 94 Views
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Open Access
Article
Clinical phenotypes of COPD and health-related quality of life: a cross-sectional study
Chee-Shee Chai, Chong-Kin Liam, Yong-Kek Pang, Diana Leh-Ching Ng, Seng-Beng Tan, Tat-Seng Wong & Jo-Ee Sia
Pages: 565-573
Published online: 01 Mar 2019
AbstractforClinical phenotypes of COPD and health-related quality of life: a cross-sectional study | Full Text | References | PDF (393.5 KB) | EPUB
  • 370 Views
  • 19 CrossRef citations
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Article
Differences in plasma amino acid levels in patients with and without bacterial infection during the early stage of acute exacerbation of COPD
Saki Inoue & Hideki Ikeda
Pages: 575-583
Published online: 01 Mar 2019
AbstractforDifferences in plasma amino acid levels in patients with and without bacterial infection during the early stage of acute exacerbation of COPD | Full Text | References | PDF (782.7 KB) | EPUB
  • 90 Views
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Article
Prevalence and factors associated with suboptimal peak inspiratory flow rates in COPD
Sohini Ghosh, Roy A Pleasants, Jill A Ohar, James F Donohue & M Bradley Drummond
Pages: 585-595
Published online: 01 Mar 2019
AbstractforPrevalence and factors associated with suboptimal peak inspiratory flow rates in COPD | Full Text | References | PDF (1.3 MB) | EPUB
  • 236 Views
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Article
Eosinophil levels predict lung function deterioration in apparently healthy individuals
Udi Shapira, Mor Krubiner, Michal Ehrenwald, Itzhak Shapira, David Zeltser, Shlomo Berliner, Ori Rogowski, Shani Shenhar-Tsarfaty & Amir Bar-Shai
Pages: 597-603
Published online: 07 Mar 2019
AbstractforEosinophil levels predict lung function deterioration in apparently healthy individuals | Full Text | References | PDF (511.2 KB) | EPUB
  • 67 Views
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Article
COPD classification models and mortality prediction capacity
Amaia Aramburu, Inmaculada Arostegui, Javier Moraza, Irantzu Barrio, Myriam Aburto, Amaia García-Loizaga, Ane Uranga, Txomin Zabala, José María Quintana & Cristóbal Esteban
Pages: 605-613
Published online: 07 Mar 2019
AbstractforCOPD classification models and mortality prediction capacity | Full Text | References | PDF (733.9 KB) | EPUB
  • 297 Views
  • 18 CrossRef citations
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Open Access
Article
Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD
Courtney Crim, Michael L Watkins, Eric D Bateman, Gregory J Feldman, Isabelle Schenkenberger, Edward M Kerwin, Catriona Crawford, Krishna Pudi, Shuyen Ho, Charlotte Baidoo & Ramiro Castro-Santamaria
Pages: 615-629
Published online: 08 Mar 2019
AbstractforRandomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD | Full Text | References | PDF (480.8 KB) | EPUB
  • 86 Views
  • 8 CrossRef citations
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Open Access
Article
Improving uptake and completion of pulmonary rehabilitation in COPD with lay health workers: feasibility of a clinical trial
Patrick White, Gill Gilworth, Simon Lewin, Lauren Hogg, Rachel Tuffnell, Stephanie J C Taylor, Nicholas S Hopkinson, Nicholas Hart, Sally J Singh & Alison J Wright
Pages: 631-643
Published online: 12 Mar 2019
AbstractforImproving uptake and completion of pulmonary rehabilitation in COPD with lay health workers: feasibility of a clinical trial | Full Text | References | PDF (313.8 KB) | EPUB
  • 153 Views
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Article
Cost-effectiveness of the COPD Patient Management European Trial home-based disease management program
Jean Bourbeau, Denis Granados, Stéphane Roze, Isabelle Durand-Zaleski, Pere Casan, Dieter Köhler, Silvia Tognella, Jose Luis Viejo, Roberto W Dal Negro & Romain Kessler
Pages: 645-657
Published online: 14 Mar 2019
AbstractforCost-effectiveness of the COPD Patient Management European Trial home-based disease management program | Full Text | References | PDF (1.2 MB) | EPUB
  • 160 Views
  • 11 CrossRef citations
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Open Access
Article
Blood pressure response to exposure to moderate altitude in patients with COPD
Esther I Schwarz, Tsogyal D Latshang, Michael Furian, Deborah Flück, Sebastian Segitz, Severine Müller-Mottet, Silvia Ulrich, Konrad E Bloch & Malcolm Kohler
Pages: 659-666
Published online: 14 Mar 2019
AbstractforBlood pressure response to exposure to moderate altitude in patients with COPD | Full Text | References | PDF (435.1 KB) | EPUB
  • 121 Views
  • 6 CrossRef citations
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Open Access
Article
AMPLIFY: a randomized, Phase III study evaluating the efficacy and safety of aclidinium/formoterol vs monocomponents and tiotropium in patients with moderate-to-very severe symptomatic COPD
Sanjay Sethi, Edward Kerwin, Henrik Watz, Gary T Ferguson, Robert M Mroz, Rosa Segarra, Eduard Molins, Diana Jarreta & Esther Garcia Gil
Pages: 667-682
Published online: 22 Mar 2019
AbstractforAMPLIFY: a randomized, Phase III study evaluating the efficacy and safety of aclidinium/formoterol vs monocomponents and tiotropium in patients with moderate-to-very severe symptomatic COPD | Full Text | References | PDF (1.4 MB) | EPUB
  • 88 Views
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Article
Exacerbations and health care resource use among patients with COPD in relation to blood eosinophil counts
Hana Müllerová, Beth Hahn, Edgar P Simard, George Mu & Umur Hatipoğlu
Pages: 683-692
Published online: 22 Mar 2019
AbstractforExacerbations and health care resource use among patients with COPD in relation to blood eosinophil counts | Full Text | References | PDF (452.1 KB) | EPUB
  • 102 Views
  • 11 CrossRef citations
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Open Access

Methodology

Article
A comparison of methodologies for the real-time identification of hospitalized patients with acute exacerbations of COPD
Parth Shah, Andrew McWilliams, Daniel Howard & Jason Roberge
Pages: 693-698
Published online: 22 Mar 2019
AbstractforA comparison of methodologies for the real-time identification of hospitalized patients with acute exacerbations of COPD | Full Text | References | PDF (182.8 KB) | EPUB
  • 74 Views
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Original Research

Article
LncRNAs NR-026690 and ENST0000447867 are upregulated in CD4+ T cells in patients with acute exacerbation of COPD
Xuefei Qi, Huilong Chen, Bohua Fu, Zhenli Huang, Yong Mou, Juan Liu, Yongjian Xu, Weining Xiong & Yong Cao
Pages: 699-711
Published online: 26 Mar 2019
AbstractforLncRNAs NR-026690 and ENST0000447867 are upregulated in CD4+ T cells in patients with acute exacerbation of COPD | Full Text | References | PDF (4.5 MB) | EPUB
  • 71 Views
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Article
Determinants of airflow limitation in Danish adults – findings from the Health2006 cohort
Camilla Boslev Baarnes, Betina H Thuesen, Allan Linneberg & Charlotte Suppli Ulrik
Pages: 713-718
Published online: 26 Mar 2019
AbstractforDeterminants of airflow limitation in Danish adults – findings from the Health2006 cohort | Full Text | References | PDF (239.9 KB) | EPUB
  • 60 Views
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Article
A clinical prediction model for hospitalized COPD exacerbations based on “treatable traits”
Anthony C A Yii, CH Loh, PY Tiew, Huiying Xu, Aza A M Taha, Jansen Koh, Jessica Tan, Therese S Lapperre, Antonio Anzueto & Augustine K H Tee
Pages: 719-728
Published online: 27 Mar 2019
AbstractforA clinical prediction model for hospitalized COPD exacerbations based on “treatable traits” | Full Text | References | PDF (574.2 KB) | EPUB
  • 165 Views
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Article
Trends and hospital outcomes of lung transplantation among patients with and without chronic obstructive pulmonary disease in Spain: a national population-based study (2001–2015)
Javier de Miguel-Díez, Ana López-de-Andres, Valentín Hernández-Barrera, José M de Miguel-Yanes, Manuel Méndez-Bailón & Rodrigo Jiménez-García
Pages: 729-737
Published online: 27 Mar 2019
AbstractforTrends and hospital outcomes of lung transplantation among patients with and without chronic obstructive pulmonary disease in Spain: a national population-based study (2001–2015) | Full Text | References | PDF (305.8 KB) | EPUB
  • 54 Views
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Open Access

Corrigendum

Correction
Ultrafine particles in airways: a novel marker of COPD exacerbation risk and inflammatory status [Corrigendum]
Pages: 739-740
Published online: 27 Mar 2019
CitationforUltrafine particles in airways: a novel marker of COPD exacerbation risk and inflammatory status [Corrigendum] | Full Text | PDF (161.3 KB) | EPUB
  • 49 Views
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Open Access

Original Research

Article
Clinical burden of illness among patients with severe eosinophilic COPD
Hana Müllerová, Wilhelmine H Meeraus, Dmitry V Galkin, Frank C Albers & Sarah H Landis
Pages: 741-755
Published online: 28 Mar 2019
AbstractforClinical burden of illness among patients with severe eosinophilic COPD | Full Text | References | PDF (621.2 KB) | EPUB
  • 97 Views
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Article
Risks of budesonide/formoterol for the treatment of stable COPD: a meta-analysis
Bin Tang, Jun Wang, Lin-lin Luo, Qiu-gen Li & Dan Huang
Pages: 757-766
Published online: 01 Apr 2019
AbstractforRisks of budesonide/formoterol for the treatment of stable COPD: a meta-analysis | Full Text | References | PDF (1.1 MB) | EPUB
  • 88 Views
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Open Access
Article
The six-minute stepper test is related to muscle strength but cannot substitute for the one repetition maximum to prescribe strength training in patients with COPD
Tristan Bonnevie, Mathilde Allingham, Guillaume Prieur, Yann Combret, David Debeaumont, Maxime Patout, Antoine Cuvelier, Catherine Viacroze, Jean-François Muir, Clement Medrinal & Francis-Edouard Gravier
Pages: 767-774
Published online: 29 Mar 2019
AbstractforThe six-minute stepper test is related to muscle strength but cannot substitute for the one repetition maximum to prescribe strength training in patients with COPD | Full Text | References | PDF (411.4 KB) | EPUB
  • 103 Views
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Article
Safety, feasibility, and effectiveness of virtual pulmonary rehabilitation in the real world
Liam Knox, Michelle Dunning, Carol-Anne Davies, Rebekah Mills-Bennet, Trystan Wyn Sion, Kerrie Phipps, Vicky Stevenson, Claire Hurlin & Keir Lewis
Pages: 775-780
Published online: 08 Apr 2019
AbstractforSafety, feasibility, and effectiveness of virtual pulmonary rehabilitation in the real world | Full Text | References | PDF (459.1 KB) | EPUB
  • 366 Views
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Article
Cross-sectional and longitudinal assessment of muscle from regular chest computed tomography scans: L1 and pectoralis muscle compared to L3 as reference in non-small cell lung cancer
Karin J C Sanders, Juliette H R J Degens, Anne-Marie C Dingemans & Annemie M W J Schols
Pages: 781-789
Published online: 03 Apr 2019
AbstractforCross-sectional and longitudinal assessment of muscle from regular chest computed tomography scans: L1 and pectoralis muscle compared to L3 as reference in non-small cell lung cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 90 Views
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Review

Review Article
Trends in the prevalence of COPD in elderly individuals in an air-polluted city in Japan: a cross-sectional study
Kenji Kotaki, Hisao Ikeda, Takeshi Fukuda, Kawano Yuhei, Fumiko Yuki, Masayuki Kawasaki, Kentaro Wakamatsu & Kenzo Sugahara
Pages: 791-798
Published online: 03 Apr 2019
AbstractforTrends in the prevalence of COPD in elderly individuals in an air-polluted city in Japan: a cross-sectional study | Full Text | References | PDF (447.6 KB) | EPUB
  • 423 Views
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Review Article
Relationship of inhaled long-acting bronchodilators with cardiovascular outcomes among patients with stable COPD: a meta-analysis and systematic review of 43 randomized trials
Chenxi Li, Wenke Cheng, Jin Guo & Wei Guan
Pages: 799-808
Published online: 11 Apr 2019
AbstractforRelationship of inhaled long-acting bronchodilators with cardiovascular outcomes among patients with stable COPD: a meta-analysis and systematic review of 43 randomized trials | Full Text | References | PDF (508.7 KB) | EPUB
  • 160 Views
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Original Research

Article
Risk factors associated with physical and mental distress in people who report a COPD diagnosis: latent class analysis of 2016 behavioral risk factor surveillance system data
Michael Stellefson, Samantha R Paige, Adam E Barry, Min Qi Wang & Avery Apperson
Pages: 809-822
Published online: 10 Apr 2019
AbstractforRisk factors associated with physical and mental distress in people who report a COPD diagnosis: latent class analysis of 2016 behavioral risk factor surveillance system data | Full Text | References | PDF (972.5 KB) | EPUB
  • 223 Views
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Article
Inflammation and infections in unreported chronic obstructive pulmonary disease exacerbations
Maria Adelaide Calderazzo, Maria-Belen Trujillo-Torralbo, Lydia Joanne Finney, Aran Singanayagam, Eteri Bakhsoliani, Vijay Padmanaban, Tatiana Kebadze, Julia Aniscenko, Sarah L Elkin, Sebastian L Johnston & Patrick Mallia
Pages: 823-832
Published online: 10 Apr 2019
AbstractforInflammation and infections in unreported chronic obstructive pulmonary disease exacerbations | Full Text | References | PDF (378.2 KB) | EPUB
  • 108 Views
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Open Access
Article
Reproducibility of fluid-phase measurements in PBS-treated sputum supernatant of healthy and stable COPD subjects
Fengyan Wang, Zhenyu Liang, Yuqiong Yang, Luqian Zhou, Lili Guan, Weiliang Wu, Mei Jiang, Weijuan Shi, Kuimiao Deng, Jianhua Chen & Rongchang Chen
Pages: 835-852
Published online: 11 Apr 2019
AbstractforReproducibility of fluid-phase measurements in PBS-treated sputum supernatant of healthy and stable COPD subjects | Full Text | References | PDF (8.9 MB) | EPUB
  • 81 Views
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Open Access
Article
Inhaled corticosteroid use by exacerbations and eosinophils: a real-world COPD population
Jørgen Vestbo, Claus F Vogelmeier, Mark Small, James Siddall, Robert Fogel & Konstantinos Kostikas
Pages: 853-861
Published online: 16 Apr 2019
AbstractforInhaled corticosteroid use by exacerbations and eosinophils: a real-world COPD population | Full Text | References | PDF (1.2 MB) | EPUB
  • 112 Views
  • 14 CrossRef citations
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Open Access
Article
Trajectories of functional exercise capacity in patients undergoing pulmonary rehabilitation
Chien-Tzu Lee, Ping-Lun Hsieh, Meng-Yueh Chien, Jung-Yien Chien, Huey-Dong Wu, Jia-Shin Lin, Hsiao-Chen Lin, Pei-Yu Yang & Li-Ying Wang
Pages: 863-870
Published online: 17 Apr 2019
AbstractforTrajectories of functional exercise capacity in patients undergoing pulmonary rehabilitation | Full Text | References | PDF (331 KB) | EPUB
  • 79 Views
  • 3 CrossRef citations
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Open Access
Article
Adherence to roflumilast under dose-escalation strategy in Korean patients with COPD
Tai Sun Park, Jieun Kang, Jae Seung Lee, Yeon-Mok Oh, Sang-Do Lee & Sei Won Lee
Pages: 871-879
Published online: 16 Apr 2019
AbstractforAdherence to roflumilast under dose-escalation strategy in Korean patients with COPD | Full Text | References | PDF (468.4 KB) | EPUB
  • 66 Views
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Open Access
Article
The relationship between oral health and COPD exacerbations
Arianne K Baldomero, Mariam Siddiqui, Chia-Yin Lo, Ashley Petersen, Alexa A Pragman, John E Connett, Ken M Kunisaki & Chris H Wendt
Pages: 881-892
Published online: 23 Apr 2019
AbstractforThe relationship between oral health and COPD exacerbations | Full Text | References | PDF (300.6 KB) | EPUB
  • 352 Views
  • 15 CrossRef citations
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Article
Survival associated with chronic obstructive pulmonary disease among SEER-Medicare beneficiaries with non-small-cell lung cancer
Shweta Shah, Christopher M Blanchette, Joseph C Coyle, Marc Kowalkowski, Susan T Arthur & Reuben Howden
Pages: 893-903
Published online: 29 Apr 2019
AbstractforSurvival associated with chronic obstructive pulmonary disease among SEER-Medicare beneficiaries with non-small-cell lung cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 151 Views
  • 9 CrossRef citations
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Article
To live a life with COPD – the consequences of symptom burden
Helena Johansson, Carina Berterö, Katarina Berg & Lise-Lotte Jonasson
Pages: 905-909
Published online: 24 Oct 2022
AbstractforTo live a life with COPD – the consequences of symptom burden | Full Text | References | PDF (153.4 KB) | EPUB
  • 805 Views
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Article
Validity of the GOLD 2017 classification in the prediction of mortality and respiratory hospitalization in patients with chronic obstructive pulmonary disease
Seung Jun Lee, Sang Suk Yun, Sunmi Ju, Jung Wan You, Yu Ji Cho, Yi Yeong Jeong, Ju-Young Kim, Ho Cheol Kim & Jong Deog Lee
Pages: 911-919
Published online: 29 Apr 2019
AbstractforValidity of the GOLD 2017 classification in the prediction of mortality and respiratory hospitalization in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (854.3 KB) | EPUB
  • 97 Views
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Review

Review Article
Congenital lobar emphysema: diagnosis and treatment options
Omer Faruk Demir, Melih Hangul & Mehmet Kose
Pages: 921-928
Published online: 01 May 2019
AbstractforCongenital lobar emphysema: diagnosis and treatment options | Full Text | References | PDF (1.9 MB) | EPUB
  • 696 Views
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Original Research

Article
Comparison of clinical characteristics and overall survival between spirometrically diagnosed chronic obstructive pulmonary disease (COPD) and non-COPD never-smoking stage I-IV non-small cell lung cancer patients
Jeong Uk Lim, Chang Dong Yeo, Chin Kook Rhee, Hye Seon Kang, Chan Kwon Park, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Hyoung Kyu Yoon & Sang Haak Lee
Pages: 929-938
Published online: 01 May 2019
AbstractforComparison of clinical characteristics and overall survival between spirometrically diagnosed chronic obstructive pulmonary disease (COPD) and non-COPD never-smoking stage I-IV non-small cell lung cancer patients | Full Text | References | PDF (539.3 KB) | EPUB
  • 113 Views
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Article
Long-term cost and utility consequences of short-term clinically important deterioration in patients with chronic obstructive pulmonary disease: results from the TORCH study
Victoria Federico Paly, Ian Naya, Necdet B Gunsoy, Maurice T Driessen, Nancy Risebrough, Andrew Briggs & Afisi S Ismaila
Pages: 939-951
Published online: 03 May 2019
AbstractforLong-term cost and utility consequences of short-term clinically important deterioration in patients with chronic obstructive pulmonary disease: results from the TORCH study | Full Text | References | PDF (719.2 KB) | EPUB
  • 92 Views
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Article
The association between blood eosinophil percent and bacterial infection in acute exacerbation of chronic obstructive pulmonary disease
Juwhan Choi, Jee Youn Oh, Young Seok Lee, Gyu Young Hur, Sung Yong Lee, Jae Jeong Shim, Kyung Ho Kang & Kyung Hoon Min
Pages: 953-959
Published online: 06 May 2019
AbstractforThe association between blood eosinophil percent and bacterial infection in acute exacerbation of chronic obstructive pulmonary disease | Full Text | References | PDF (633 KB) | EPUB
  • 121 Views
  • 13 CrossRef citations
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Open Access
Article
Sex-related differences in management of Swedish patients with a clinical diagnosis of chronic obstructive pulmonary disease
Joakim Åberg, Mikael Hasselgren, Scott Montgomery, Karin Lisspers, Björn Ställberg, Christer Janson & Josefin Sundh
Pages: 961-969
Published online: 07 May 2019
AbstractforSex-related differences in management of Swedish patients with a clinical diagnosis of chronic obstructive pulmonary disease | Full Text | References | PDF (467.3 KB) | EPUB
  • 99 Views
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Open Access
Article
The acute wheezy adult with airways disease in the emergency department: a retrospective case-note review of exacerbations of COPD
REK Russell, S Beer, ID Pavord, R Pullinger & M Bafadhel
Pages: 971-977
Published online: 07 May 2019
AbstractforThe acute wheezy adult with airways disease in the emergency department: a retrospective case-note review of exacerbations of COPD | Full Text | References | PDF (693.3 KB) | EPUB
  • 78 Views
  • 6 CrossRef citations
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Open Access
Article
Fine-particulate matter aggravates cigarette smoke extract–induced airway inflammation via Wnt5a–ERK pathway in COPD
Zhihua Wang, Junling Zhao, Ting Wang, Xiaohui Du & Jungang Xie
Pages: 979-994
Published online: 09 May 2019
AbstractforFine-particulate matter aggravates cigarette smoke extract–induced airway inflammation via Wnt5a–ERK pathway in COPD | Full Text | References | PDF (3.2 MB) | EPUB
  • 160 Views
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Article
Impact of COPD diagnosis timing on clinical and economic outcomes: the ARCTIC observational cohort study
Kjell Larsson, Christer Janson, Björn Ställberg, Karin Lisspers, Petter Olsson, Konstantinos Kostikas, Jean-Bernard Gruenberger, Florian S Gutzwiller, Milica Uhde, Leif Jorgensen & Gunnar Johansson
Pages: 995-1008
Published online: 13 May 2019
AbstractforImpact of COPD diagnosis timing on clinical and economic outcomes: the ARCTIC observational cohort study | Full Text | References | PDF (1.4 MB) | EPUB
  • 299 Views
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Review

Review Article
Lipid metabolism in chronic obstructive pulmonary disease
Haipin Chen, Zhouyang Li, Lingling Dong, Yinfang Wu, Huahao Shen & Zhihua Chen
Pages: 1009-1018
Published online: 13 May 2019
AbstractforLipid metabolism in chronic obstructive pulmonary disease | Full Text | References | PDF (414.7 KB) | EPUB
  • 330 Views
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Original Research

Article
Medication management patterns among Medicare beneficiaries with chronic obstructive pulmonary disease who initiate nebulized arformoterol treatment
Bartolome R Celli, Maryam Navaie, Zhun Xu, Soojin Cho-Reyes, Carole Dembek & Todd P Gilmer
Pages: 1019-1031
Published online: 15 May 2019
AbstractforMedication management patterns among Medicare beneficiaries with chronic obstructive pulmonary disease who initiate nebulized arformoterol treatment | Full Text | References | PDF (400.7 KB) | EPUB
  • 83 Views
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Open Access
Article
COPD patients’ experiences, self-reported needs, and needs-driven strategies to cope with self-management
Jonina Sigurgeirsdottir, Sigridur Halldorsdottir, Ragnheidur Harpa Arnardottir, Gunnar Gudmundsson & Eythor Hreinn Bjornsson
Pages: 1033-1043
Published online: 16 May 2019
AbstractforCOPD patients’ experiences, self-reported needs, and needs-driven strategies to cope with self-management | Full Text | References | PDF (337.6 KB) | EPUB
  • 1701 Views
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Review

Article
Targeting IL-5 in COPD
Dharani K Narendra & Nicola A Hanania
Pages: 1045-1051
Published online: 16 May 2019
AbstractforTargeting IL-5 in COPD | Full Text | References | PDF (456.7 KB) | EPUB
  • 135 Views
  • 22 CrossRef citations
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Original Research

Article
Long QT and death in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease is not related to electrolyte disorders
Shani Zilberman-Itskovich, Eldad Rahamim, Faina Tsiporin-Havatinsky, Tomer Ziv-Baran, Ahuva Golik & Ronit Zaidenstein
Pages: 1053-1061
Published online: 20 May 2019
AbstractforLong QT and death in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease is not related to electrolyte disorders | Full Text | References | PDF (231.1 KB) | EPUB
  • 116 Views
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Open Access
Article
Inhaled corticosteroids, blood eosinophils, and FEV1 decline in patients with COPD in a large UK primary health care setting
Hannah R Whittaker, Hana Müllerova, Deborah Jarvis, Neil C Barnes, Paul W Jones, Chris H Compton, Steven J Kiddle & Jennifer K Quint
Pages: 1063-1073
Published online: 23 May 2019
AbstractforInhaled corticosteroids, blood eosinophils, and FEV1 decline in patients with COPD in a large UK primary health care setting | Full Text | References | PDF (507.5 KB) | EPUB
  • 110 Views
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Article
Decline in FEV1 and hospitalized exacerbations in individuals with severe alpha-1 antitrypsin deficiency
Adriana-Maria Hiller, Eeva Piitulainen, Lars Jehpsson & Hanan Tanash
Pages: 1075-1083
Published online: 23 May 2019
AbstractforDecline in FEV1 and hospitalized exacerbations in individuals with severe alpha-1 antitrypsin deficiency | Full Text | References | PDF (492.2 KB) | EPUB
  • 122 Views
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Review

Review Article
Long-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature
Gaetano Caramori, Paolo Ruggeri, Fabio Arpinelli, Laura Salvi & Giuseppe Girbino
Pages: 1085-1097
Published online: 23 May 2019
AbstractforLong-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature | Full Text | References | PDF (867.9 KB) | EPUB
  • 166 Views
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Original Research

Article
Mean platelet volume as a predictor of pulmonary hypertension in patients with stable COPD
Maha Fathy Mohamed, Asmaa Ali, Ahmad Abbas, Mohammad Shafiq Awad, Mohammad Gouda & Amany M Sediq
Pages: 1099-1108
Published online: 23 May 2019
AbstractforMean platelet volume as a predictor of pulmonary hypertension in patients with stable COPD | Full Text | References | PDF (1.9 MB) | EPUB
  • 134 Views
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Article
Comparison of impedance measured by the forced oscillation technique and pulmonary functions, including static lung compliance, in obstructive and interstitial lung disease
Naoya Takeichi, Haruna Yamazaki & Keisaku Fujimoto
Pages: 1109-1118
Published online: 24 May 2019
AbstractforComparison of impedance measured by the forced oscillation technique and pulmonary functions, including static lung compliance, in obstructive and interstitial lung disease | Full Text | References | PDF (641.7 KB) | EPUB
  • 139 Views
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Review

Review Article
New insights into early intervention of chronic obstructive pulmonary disease with mild airflow limitation
Yilan Sun & Jianying Zhou
Pages: 1119-1125
Published online: 23 May 2019
AbstractforNew insights into early intervention of chronic obstructive pulmonary disease with mild airflow limitation | Full Text | References | PDF (265.9 KB) | EPUB
  • 175 Views
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Review Article
Activity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions
Nicola A Hanania & Denis E O'Donnell
Pages: 1127-1138
Published online: 24 May 2019
AbstractforActivity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions | Full Text | References | PDF (1.1 MB) | EPUB
  • 1174 Views
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Review Article
The etiologic origins for chronic obstructive pulmonary disease
Xinwei Huang, Xi Mu, Li Deng, Aili Fu, Endong Pu, Tao Tang & Xiangyang Kong
Pages: 1139-1158
Published online: 27 May 2019
AbstractforThe etiologic origins for chronic obstructive pulmonary disease | Full Text | References | PDF (1.2 MB) | EPUB
  • 658 Views
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Original Research

Article
Outcomes of laparoscopic cholecystectomy in patients with and without COPD
Kuang-Ming Liao, Chien-Jen Tseng, Yi-Chen Chen, Jhi-Joung Wang & Chung-Han Ho
Pages: 1159-1165
Published online: 27 May 2019
AbstractforOutcomes of laparoscopic cholecystectomy in patients with and without COPD | Full Text | References | PDF (551.7 KB) | EPUB
  • 143 Views
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Open Access
Article
Efficacy of tiotropium and olodaterol combination therapy on dynamic lung hyperinflation evaluated by hyperventilation in COPD: an open-label, comparative before and after treatment study
Shohei Kawachi & Keisaku Fujimoto
Pages: 1167-1176
Published online: 27 May 2019
AbstractforEfficacy of tiotropium and olodaterol combination therapy on dynamic lung hyperinflation evaluated by hyperventilation in COPD: an open-label, comparative before and after treatment study | Full Text | References | PDF (1,019.3 KB) | EPUB
  • 76 Views
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Short Report

Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab
Leena George, Adam Wright, Vijay Mistry, Amanda Sutcliffe, Latifa Chachi, Koirobi Haldar, Mohammadali Yavari Ramsheh, Matthew Richardson, René van der Merwe, Ubaldo Martin, Paul Newbold & Christopher E Brightling
Pages: 1177-1185
Published online: 05 Jun 2019
AbstractforSputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab | Full Text | References | PDF (1.5 MB) | EPUB
  • 106 Views
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Original Research

Article
Quantification of inaccurate diagnosis of COPD in primary care medicine: an analysis of the COACH clinical audit
María Abad-Arranz, Ana Moran-Rodríguez, Enrique Mascarós Balaguer, Carmen Quintana Velasco, Laura Abad Polo, Sara Núñez Palomo, Jaime Gonzálvez Rey, Ana María Fernández Vargas, Antonio Hidalgo Requena, Jose Manuel Helguera Quevedo, Marina García Pardo, Jose Luis Lopez-Campos & on behalf of the COACH study investigators
Pages: 1187-1194
Published online: 06 Jun 2019
AbstractforQuantification of inaccurate diagnosis of COPD in primary care medicine: an analysis of the COACH clinical audit | Full Text | References | PDF (257.9 KB) | EPUB
  • 90 Views
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Article
Comparative analysis of medical expenditure with nebulized budesonide versus systemic corticosteroids in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease in China
Jing Zhang, Wanzhen Yao, Xuedan You, Tianyi Liu & Yuantao Liu
Pages: 1195-1207
Published online: 29 May 2019
AbstractforComparative analysis of medical expenditure with nebulized budesonide versus systemic corticosteroids in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease in China | Full Text | References | PDF (453.3 KB) | EPUB
  • 76 Views
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Article
COPD: misuse of inhaler devices in clinical practice
A Duarte-de-Araújo, P Teixeira, V Hespanhol & J Correia-de-Sousa
Pages: 1209-1217
Published online: 30 May 2019
AbstractforCOPD: misuse of inhaler devices in clinical practice | Full Text | References | PDF (834.3 KB) | EPUB
  • 345 Views
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Article
Seasonal variations in objectively assessed physical activity among people with COPD in two Nordic countries and Australia: a cross-sectional study
Hanne Hoaas, Paolo Zanaboni, Audhild Hjalmarsen, Bente Morseth, Birthe Dinesen, Angela T Burge, Narelle S Cox & Anne E Holland
Pages: 1219-1228
Published online: 05 Jun 2019
AbstractforSeasonal variations in objectively assessed physical activity among people with COPD in two Nordic countries and Australia: a cross-sectional study | Full Text | References | PDF (284.6 KB) | EPUB
  • 143 Views
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Article
High flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study
Jiayan Sun, Yujie Li, Bingyu Ling, Qingcheng Zhu, Yingying Hu, Dingyu Tan, Ping Geng & Jun Xu
Pages: 1229-1237
Published online: 05 Jun 2019
AbstractforHigh flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study | Full Text | References | PDF (528 KB) | EPUB
  • 1034 Views
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Article
The efficacy of a flipping education program on improving self-management in patients with chronic obstructive pulmonary disease: a randomized controlled trial
Yi-Ya Chang & Yu-Tzu Dai
Pages: 1239-1250
Published online: 06 Jun 2019
AbstractforThe efficacy of a flipping education program on improving self-management in patients with chronic obstructive pulmonary disease: a randomized controlled trial | Full Text | References | PDF (326 KB) | EPUB
  • 272 Views
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Review

Review Article
Evidence-based review of data on the combination inhaler umeclidinium/vilanterol in patients with COPD
Timothy E Albertson, Willis S Bowman, Richart W Harper, Regina M Godbout & Susan Murin
Pages: 1251-1265
Published online: 06 Jun 2019
AbstractforEvidence-based review of data on the combination inhaler umeclidinium/vilanterol in patients with COPD | Full Text | References | PDF (345.2 KB) | EPUB
  • 205 Views
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Open Access

Expert Opinion

Withdrawal of inhaled corticosteroids in COPD patients: rationale and algorithms
Sergey Avdeev, Zaurbek Aisanov, Vladimir Arkhipov, Andrey Belevskiy, Igor Leshchenko, Svetlana Ovcharenko, Evgeny Shmelev & Marc Miravitlles
Pages: 1267-1280
Published online: 10 Jun 2019
AbstractforWithdrawal of inhaled corticosteroids in COPD patients: rationale and algorithms | Full Text | References | PDF (1 MB) | EPUB
  • 214 Views
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Original Research

Article
Can a physical activity similar to activities of daily living cause dynamic hyperinflation and change the thoracoabdominal configuration in patients with chronic obstructive pulmonary disease?
Aldenice Magalhães Capeletti, Adriana do Carmo Santos Sousa, Carla Lima Feitoza, Renata Pedrolongo Basso-Vanelli, Evelim LFD Gomes & Dirceu Costa
Pages: 1281-1287
Published online: 13 Jun 2019
AbstractforCan a physical activity similar to activities of daily living cause dynamic hyperinflation and change the thoracoabdominal configuration in patients with chronic obstructive pulmonary disease? | Full Text | References | PDF (1.3 MB) | EPUB
  • 78 Views
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Open Access

Review

Review Article
Effects of long-term macrolide therapy at low doses in stable COPD
Yueqin Cao, Shurui Xuan, Yunhui Wu & Xin Yao
Pages: 1289-1298
Published online: 12 Jun 2019
AbstractforEffects of long-term macrolide therapy at low doses in stable COPD | Full Text | References | PDF (1.9 MB) | EPUB
  • 293 Views
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Commentary

Patient registries for home oxygen research and evaluation
Yves Lacasse, Jerry A Krishnan, François Maltais & Magnus Ekström
Pages: 1299-1304
Published online: 18 Jun 2019
AbstractforPatient registries for home oxygen research and evaluation | Full Text | References | PDF (276.5 KB) | EPUB
  • 82 Views
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Original Research

Article
Cigarette smoke exposure reduces leukemia inhibitory factor levels during respiratory syncytial viral infection
Justin Poon, Michael Campos, Robert F Foronjy, Sridesh Nath, Gayatri Gupta, Christopher Railwah, Abdoulaye J Dabo, Nathalie Baumlin, Matthias Salathe & Patrick Geraghty
Pages: 1305-1315
Published online: 18 Jun 2019
AbstractforCigarette smoke exposure reduces leukemia inhibitory factor levels during respiratory syncytial viral infection | Full Text | References | PDF (1.1 MB) | EPUB
  • 70 Views
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Review

Review Article
The use of wearable technology to monitor physical activity in patients with COPD: a literature review
Paraskevi Pericleous & Tjeerd Pieter van Staa
Pages: 1317-1322
Published online: 19 Jun 2019
AbstractforThe use of wearable technology to monitor physical activity in patients with COPD: a literature review | Full Text | References | PDF (312.8 KB) | EPUB
  • 499 Views
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Original Research

Article
Evaluation of lung parenchyma, blood vessels, and peripheral blood lymphocytes as a potential source of acute phase reactants in patients with COPD
Elena Arellano-Orden, Carmen Calero, Cecilia López-Ramírez, Verónica Sánchez-López, José Luis López-Villalobos, María Abad Arranz, Ana Blanco-Orozco, Remedios Otero-Candelera & José Luis López-Campos
Pages: 1323-1332
Published online: 24 Oct 2022
AbstractforEvaluation of lung parenchyma, blood vessels, and peripheral blood lymphocytes as a potential source of acute phase reactants in patients with COPD | Full Text | References | PDF (1 MB) | EPUB
  • 65 Views
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Open Access
Article
Clinical features of three-dimensional computed tomography-based radiologic phenotypes of chronic obstructive pulmonary disease
Masato Karayama, Naoki Inui, Hideki Yasui, Masato Kono, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Dai Hashimoto, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Hiroshi Watanabe & Takafumi Suda
Pages: 1333-1342
Published online: 24 Jun 2019
AbstractforClinical features of three-dimensional computed tomography-based radiologic phenotypes of chronic obstructive pulmonary disease | Full Text | References | PDF (980.7 KB) | EPUB
  • 139 Views
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Open Access
Article
Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care
A Blakemore, C Dickens, CA Chew-Graham, CW Afzal, B Tomenson, PA Coventry & E Guthrie
Pages: 1343-1353
Published online: 28 Jun 2019
AbstractforDepression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care | Full Text | References | PDF (360.4 KB) | EPUB
  • 262 Views
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Article
Impact of transcutaneous neuromuscular electrical stimulation or resistance exercise on skeletal muscle mRNA expression in COPD
Lorna E Latimer, Despina Constantin, Neil J Greening, Lori Calvert, Manoj K Menon, Michael C Steiner & Paul L Greenhaff
Pages: 1355-1364
Published online: 28 Jun 2019
AbstractforImpact of transcutaneous neuromuscular electrical stimulation or resistance exercise on skeletal muscle mRNA expression in COPD | Full Text | References | PDF (714.5 KB) | EPUB
  • 98 Views
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Open Access
Article
Impact of cough and mucus on COPD patients: primary insights from an exploratory study with an Online Patient Community
Nigel Cook, Jennifer Gey, Beyza Oezel, Alexander J Mackay, Chitresh Kumari, Vinay Preet Kaur, Noel Larkin, Jennifer Harte, Sara Vergara-Muro & Florian S Gutzwiller
Pages: 1365-1376
Published online: 24 Jun 2019
AbstractforImpact of cough and mucus on COPD patients: primary insights from an exploratory study with an Online Patient Community | Full Text | References | PDF (755.3 KB) | EPUB
  • 286 Views
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Open Access
Article
Patient-reported outcomes of dual bronchodilator fixed-dose combination versus bronchodilator monotherapy in individuals with COPD
Charlie Strange, Valery Walker, Michael DePietro, Junliang Tong, Jonathan Kurlander, Maureen Carlyle, Lauren A Millette & Eric Wittbrodt
Pages: 1377-1388
Published online: 28 Jun 2019
AbstractforPatient-reported outcomes of dual bronchodilator fixed-dose combination versus bronchodilator monotherapy in individuals with COPD | Full Text | References | PDF (418.2 KB) | EPUB
  • 75 Views
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Article
Prediction of first acute exacerbation using COPD subtypes identified by cluster analysis
Hee-Young Yoon, So Young Park, Chang Hoon Lee, Min-Kwang Byun, Joo Ock Na, Jae Seung Lee, Won-Yeon Lee, Kwang Ha Yoo, Ki-Suck Jung & Jin Hwa Lee
Pages: 1389-1397
Published online: 28 Jun 2019
AbstractforPrediction of first acute exacerbation using COPD subtypes identified by cluster analysis | Full Text | References | PDF (840.9 KB) | EPUB
  • 115 Views
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Open Access
Article
Predictors in routine practice of 6-min walking distance and oxygen desaturation in patients with COPD: impact of comorbidities
Thierry Perez, Gaëtan Deslée, Pierre Régis Burgel, Denis Caillaud, Olivier Le Rouzic, Maeva Zysman, Roger Escamilla, Gilles Jebrak, Pascal Chanez, Isabelle Court-Fortune, Graziella Brinchault-Rabin, Pascale Nesme-Meyer, Jean-Louis Paillasseur, Nicolas Roche & On behalf of the Initiatives BPCO Scientific Committee
Pages: 1399-1410
Published online: 02 Jul 2019
AbstractforPredictors in routine practice of 6-min walking distance and oxygen desaturation in patients with COPD: impact of comorbidities | Full Text | References | PDF (1.1 MB) | EPUB
  • 149 Views
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Open Access
Article
Nasal high-flow versus noninvasive ventilation in patients with chronic hypercapnic COPD
Jens Bräunlich, Dominic Dellweg, Andreas Bastian, Stephan Budweiser, Winfried Randerath, Dora Triché, Martin Bachmann, Christian Kähler, Abdel Hakim Bayarassou, Irmhild Mäder, Jens Geiseler, Norbert Köhler, David Petroff & Hubert Wirtz
Pages: 1411-1421
Published online: 05 Jul 2019
AbstractforNasal high-flow versus noninvasive ventilation in patients with chronic hypercapnic COPD | Full Text | References | PDF (1.7 MB) | EPUB
  • 352 Views
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Open Access
Article
Determinants of healthcare utilization and costs in COPD patients: first longitudinal results from the German COPD cohort COSYCONET
Danalyn Byng, Johanna I Lutter, Margarethe E Wacker, Rudolf A Jörres, Xiaofei Liu, Stefan Karrasch, Holger Schulz, Claus Vogelmeier, Rolf Holle & On behalf of the COSYCONET Consortium
Pages: 1423-1439
Published online: 05 Jul 2019
AbstractforDeterminants of healthcare utilization and costs in COPD patients: first longitudinal results from the German COPD cohort COSYCONET | Full Text | References | PDF (320.6 KB) | EPUB
  • 294 Views
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Open Access
Article
Assessment of physical functioning and handling of tiotropium/olodaterol Respimat® in patients with COPD in a real-world clinical setting
Karl-Otto Steinmetz, Birgit Abenhardt, Stefan Pabst, Michaela Hänsel, Anke Kondla, Valentina Bayer & Roland Buhl
Pages: 1441-1453
Published online: 04 Jul 2019
AbstractforAssessment of physical functioning and handling of tiotropium/olodaterol Respimat® in patients with COPD in a real-world clinical setting | Full Text | References | PDF (526.2 KB) | EPUB
  • 101 Views
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Article
Increased risk of peripheral arterial occlusive diseases in patients with chronic obstructive pulmonary disease: a nationwide study in Taiwan
Kuang-Ming Liao, Lu-Ting Kuo & Hsueh-Yi Lu
Pages: 1455-1464
Published online: 04 Jul 2019
AbstractforIncreased risk of peripheral arterial occlusive diseases in patients with chronic obstructive pulmonary disease: a nationwide study in Taiwan | Full Text | References | PDF (812.4 KB) | EPUB
  • 97 Views
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Review

Article
Personalized medicine for patients with COPD: where are we?
Frits ME Franssen, Peter Alter, Nadav Bar, Birke J Benedikter, Stella Iurato, Dieter Maier, Michael Maxheim, Fabienne K Roessler, Martijn A Spruit, Claus F Vogelmeier, Emiel FM Wouters, Bernd Schmeck & On behalf of the SysMed-COPD consortium
Pages: 1465-1484
Published online: 09 Jul 2019
AbstractforPersonalized medicine for patients with COPD: where are we? | Full Text | References | PDF (898.2 KB) | EPUB
  • 762 Views
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Original Research

Article
Effects of noninvasive ventilation on the coordination between breathing and swallowing in patients with chronic obstructive pulmonary disease
Ryuji Hori, Rika Ishida, Masaaki Isaka, Takahito Nakamura & Yoshitaka Oku
Pages: 1485-1494
Published online: 08 Jul 2019
AbstractforEffects of noninvasive ventilation on the coordination between breathing and swallowing in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (757.4 KB) | EPUB
  • 136 Views
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Open Access

Clinical Trial Report

Impact of vitamin D on spirometry findings and quality of life in patients with chronic obstructive pulmonary disease: a randomized, double-blinded, placebo-controlled clinical trial
Ali Alavi Foumani, Mojtaba Mehrdad, Alireza Jafarinezhad, Khadijeh Nokani & Alireza Jafari
Pages: 1495-1501
Published online: 08 Jul 2019
AbstractforImpact of vitamin D on spirometry findings and quality of life in patients with chronic obstructive pulmonary disease: a randomized, double-blinded, placebo-controlled clinical trial | Full Text | References | PDF (268.2 KB) | EPUB
  • 216 Views
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Open Access

Review

Review Article
Status of and strategies for improving adherence to COPD treatment
José Luis López-Campos, Esther Quintana Gallego & Laura Carrasco Hernández
Pages: 1503-1515
Published online: 10 Jul 2019
AbstractforStatus of and strategies for improving adherence to COPD treatment | Full Text | References | PDF (1.6 MB) | EPUB
  • 2261 Views
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Open Access

Original Research

Article
Effect of ambient air quality on exacerbation of COPD in patients and its potential mechanism
Peng Yan, Pengfei Liu, Rong Lin, Kun Xiao, Sheling Xie, Kaifei Wang, Yuhan Zhang, Xanxue He, Shifeng Zhao, Xingang Zhang, Martin Liu & Lixin Xie
Pages: 1517-1526
Published online: 10 Jul 2019
AbstractforEffect of ambient air quality on exacerbation of COPD in patients and its potential mechanism | Full Text | References | PDF (2.5 MB) | EPUB
  • 132 Views
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Open Access
Article
The relationship between acrolein and oxidative stress in COPD: in systemic plasma and in local lung tissue
Masanori Yasuo, Yunden Droma, Yoshiaki Kitaguchi, Michiko Ito, Hitomi Imamura, Masatomo Kawakubo & Masayuki Hanaoka
Pages: 1527-1537
Published online: 24 Oct 2022
AbstractforThe relationship between acrolein and oxidative stress in COPD: in systemic plasma and in local lung tissue | Full Text | References | PDF (1.4 MB) | EPUB
  • 150 Views
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Open Access
Article
The effects of single inhaler triple therapy vs single inhaler dual therapy or separate triple therapy for the management of chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled trials
Chih-Cheng Lai, Cheng-Hsin Chen, Charlotte Yu Hsuan Lin, Cheng-Yi Wang & Ya-Hui Wang
Pages: 1539-1548
Published online: 11 Jul 2019
AbstractforThe effects of single inhaler triple therapy vs single inhaler dual therapy or separate triple therapy for the management of chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled trials | Full Text | References | PDF (2.4 MB) | EPUB
  • 294 Views
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Open Access
Article
Effects of air pollution on acute exacerbation of chronic obstructive pulmonary disease: a descriptive retrospective study (pol-AECOPD)
Jairo A Morantes-Caballero & Hugo Alberto Fajardo Rodriguez
Pages: 1549-1557
Published online: 11 Jul 2019
AbstractforEffects of air pollution on acute exacerbation of chronic obstructive pulmonary disease: a descriptive retrospective study (pol-AECOPD) | Full Text | References | PDF (672.5 KB) | EPUB
  • 167 Views
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Open Access
Article
Downregulated level of insulin in COPD patients during AE; role beyond glucose control?
Wenjing Ruan, Chao Yan, Huiqi Zhu, Shuwen Wang, Xuan Jia, Lingyan Shao, Zhihao Xu & Kejing Ying
Pages: 1559-1566
Published online: 15 Jul 2019
AbstractforDownregulated level of insulin in COPD patients during AE; role beyond glucose control? | Full Text | References | PDF (1.8 MB) | EPUB
  • 64 Views
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Open Access

Corrigendum

Correction
High flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study [Corrigendum]
Page: 1567
Published online: 15 Jul 2019
CitationforHigh flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study [Corrigendum] | Full Text | PDF (151.3 KB) | EPUB
  • 51 Views
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Original Research

Article
Elderly patients with COPD require more health care than elderly heart failure patients do in a hospital-based home care setting
Hans Lennart Persson, Johan Lyth, Ann-Britt Wiréhn & Leili Lind
Pages: 1569-1581
Published online: 16 Jul 2019
AbstractforElderly patients with COPD require more health care than elderly heart failure patients do in a hospital-based home care setting | Full Text | References | PDF (1.2 MB) | EPUB
  • 263 Views
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Open Access
Article
Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis?
Felix W Feldhaus, Dorothea Cornelia Theilig, Ralf-Harto Hubner, Jan-Martin Kuhnigk, Konrad Neumann & Felix Doellinger
Pages: 1583-1593
Published online: 17 Jul 2019
AbstractforQuantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? | Full Text | References | PDF (1 MB) | EPUB
  • 86 Views
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Open Access

Short Report

Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study
Kyu Yean Kim, Marc Miravitlles, Pawel Sliwinski, Richard Costello, Victoria Carter, Jessica Tan, Therese Sophie Lapperre, Bernardino Alcazar, Caroline Gouder, Cristina Esquinas, Juan Luis García-Rivero, Anu Kemppinen, Augustine Tee, Miguel Roman-Rodríguez, Juan José Soler-Cataluña, David Price & Chin Kook Rhee
Pages: 1595-1601
Published online: 24 Oct 2022
AbstractforComparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study | Full Text | References | PDF (228 KB) | EPUB
  • 115 Views
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Commentary

Article
Epithelial–mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics
Mathew Suji Eapen, Pawan Sharma, Archana Vijay Gaikwad, Wenying Lu, Stephen Myers, Philip M Hansbro & Sukhwinder Singh Sohal
Pages: 1603-1610
Published online: 18 Jul 2019
AbstractforEpithelial–mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics | Full Text | References | PDF (901 KB) | EPUB
  • 107 Views
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Original Research

Article
Overexpression of chitotriosidase and YKL-40 in peripheral blood and sputum of healthy smokers and patients with chronic obstructive pulmonary disease
Sebastian Majewski, Damian Tworek, Karolina Szewczyk, Justyna Kiszałkiewicz, Zofia Kurmanowska, Ewa Brzeziańska-Lasota, Hanna Jerczyńska, Adam Antczak, Wojciech Jerzy Piotrowski & Paweł Górski
Pages: 1611-1631
Published online: 22 Jul 2019
AbstractforOverexpression of chitotriosidase and YKL-40 in peripheral blood and sputum of healthy smokers and patients with chronic obstructive pulmonary disease | Full Text | References | PDF (4.2 MB) | EPUB
  • 74 Views
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Open Access
Article
Opportunistic screening for COPD in primary care: a pooled analysis of 6,710 symptomatic smokers and ex-smokers
Andreas Katsimigas, Oliver Djurhuus Tupper & Charlotte Suppli Ulrik
Pages: 1633-1638
Published online: 22 Jul 2019
AbstractforOpportunistic screening for COPD in primary care: a pooled analysis of 6,710 symptomatic smokers and ex-smokers | Full Text | References | PDF (256.2 KB) | EPUB
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Article
Prevalence and prognostic ability of the GOLD 2017 classification compared to the GOLD 2011 classification in a Norwegian COPD cohort
Lan Ai Kieu Le, Ane Johannessen, Jon Andrew Hardie, Odd Erik Johansen, Amund Gulsvik, Bjørn Egil Vikse & Per Bakke
Pages: 1639-1655
Published online: 23 Jul 2019
AbstractforPrevalence and prognostic ability of the GOLD 2017 classification compared to the GOLD 2011 classification in a Norwegian COPD cohort | Full Text | References | PDF (2.4 MB) | EPUB
  • 117 Views
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Open Access
Article
Normal lung attenuation distribution and lung volume on computed tomography in a Chinese population
Ting Cheng, Yong Li, Shuai Pang, HuanYing Wan, GuoChao Shi, QiJian Cheng, QingYun Li, ZiLai Pan & ShaoGuang Huang
Pages: 1657-1668
Published online: 24 Oct 2022
AbstractforNormal lung attenuation distribution and lung volume on computed tomography in a Chinese population | Full Text | References | PDF (704.7 KB) | EPUB
  • 130 Views
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Article
Peripheral blood CD4+ T cell populations by CD25 and Foxp3 expression as a potential biomarker: reflecting inflammatory activity in chronic obstructive pulmonary disease
Zhao-Ji Meng, Jiang-Hua Wu, Mei Zhou, Sheng-Wen Sun, Shuai-Ying Miao, Hong-Li Han, Long Chen & Xian-Zhi Xiong
Pages: 1669-1680
Published online: 30 Jul 2019
AbstractforPeripheral blood CD4+ T cell populations by CD25 and Foxp3 expression as a potential biomarker: reflecting inflammatory activity in chronic obstructive pulmonary disease | Full Text | References | PDF (1.5 MB) | EPUB
  • 104 Views
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Review

Review Article
eHealth for people with COPD in the Netherlands: a scoping review
Cynthia Hallensleben, Sanne van Luenen, Emiel Rolink, Hans C Ossebaard & Niels H Chavannes
Pages: 1681-1690
Published online: 26 Jul 2019
AbstractforeHealth for people with COPD in the Netherlands: a scoping review | Full Text | References | PDF (1.9 MB) | EPUB
  • 337 Views
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Open Access

Original Research

Article
End-of-life care in individuals with respiratory diseases: a population study comparing the dying experience between those with chronic obstructive pulmonary disease and lung cancer
Tetyana Kendzerska, Jason W Nickerson, Amy T Hsu, Andrea S Gershon, Robert Talarico, Sunita Mulpuru, Smita Pakhale & Peter Tanuseputro
Pages: 1691-1701
Published online: 24 Oct 2022
AbstractforEnd-of-life care in individuals with respiratory diseases: a population study comparing the dying experience between those with chronic obstructive pulmonary disease and lung cancer | Full Text | References | PDF (2.1 MB) | EPUB
  • 200 Views
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Open Access
Article
Identification of relevant variables and construction of a multidimensional index for predicting mortality in COPD patients
Limei Xu, Tiaofei Ye, Jiahui Li, Yuhe Hu, Wenhui Xu, Kai Wang, Chunquan Ou & Xin Chen
Pages: 1703-1711
Published online: 24 Oct 2022
AbstractforIdentification of relevant variables and construction of a multidimensional index for predicting mortality in COPD patients | Full Text | References | PDF (932.4 KB) | EPUB
  • 68 Views
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Open Access
Article
Global use, utility, and methods of tele-health in COPD: a health care provider survey
Ahmed M Alrajeh, Yousef S Aldabayan, Abdulelah M Aldhair, Elisha Pickett, Shumonta A Quaderi, Jaber S Alqahtani, Marc Lipman & John R Hurst
Pages: 1713-1719
Published online: 01 Aug 2019
AbstractforGlobal use, utility, and methods of tele-health in COPD: a health care provider survey | Full Text | References | PDF (335.2 KB) | EPUB
  • 182 Views
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Open Access
Article
Real-world effectiveness of umeclidinium/vilanterol versus fluticasone propionate/salmeterol as initial maintenance therapy for chronic obstructive pulmonary disease (COPD): a retrospective cohort study
Chad Moretz, Lucie Sharpsten, Lindsay GS Bengtson, Eleena Koep, Lisa Le, Junliang Tong, Richard H Stanford, Beth Hahn & Riju Ray
Pages: 1721-1737
Published online: 01 Aug 2019
AbstractforReal-world effectiveness of umeclidinium/vilanterol versus fluticasone propionate/salmeterol as initial maintenance therapy for chronic obstructive pulmonary disease (COPD): a retrospective cohort study | Full Text | References | PDF (2 MB) | EPUB
  • 166 Views
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Open Access

Corrigendum

Correction
The use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes [Corrigendum]
Page: 1739
Published online: 02 Aug 2019
CitationforThe use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes [Corrigendum] | Full Text | PDF (174.8 KB) | EPUB
  • 56 Views
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Original Research

Article
SIRT1 protects against urban particulate matter-induced airway inflammation
Tianwen Lai, Xiaoxia Wen, Dong Wu, Guomei Su, Yun Gao, Cuifen Chen, Weiquan Wu, Yingying Lv, Zhanghui Chen, Quanchao Lv, Wen Li, Dongming Li, Min Chen & Bin Wu
Pages: 1741-1752
Published online: 05 Aug 2019
AbstractforSIRT1 protects against urban particulate matter-induced airway inflammation | Full Text | References | PDF (3.5 MB) | EPUB
  • 112 Views
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Open Access
Article
Bronchodilators for hyperinflation in COPD associated with biomass smoke: clinical trial
Alejandra Ramírez-Venegas, Mónica Velázquez-Uncal, Adrián Aranda-Chávez, Nicolás Eduardo Guzmán-Bouilloud, María Eugenia Mayar-Maya, José Luis Pérez Lara-Albisua, Rafael de Jesus Hernández-Zenteno, Fernando Flores-Trujillo & Raúl H Sansores
Pages: 1753-1762
Published online: 06 Aug 2019
AbstractforBronchodilators for hyperinflation in COPD associated with biomass smoke: clinical trial | Full Text | References | PDF (782.1 KB) | EPUB
  • 73 Views
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Open Access

Short Report

Review Article
Extreme desert dust storms and COPD morbidity on the island of Crete
Christina Lorentzou, Giorgos Kouvarakis, Georgios V Kozyrakis, Nikolaos A Kampanis, Irene Trahanatzi, Othon Fraidakis, Nikolaos Tzanakis, Maria Kanakidou, Panagiotis Agouridakis & George Notas
Pages: 1763-1768
Published online: 06 Aug 2019
AbstractforExtreme desert dust storms and COPD morbidity on the island of Crete | Full Text | References | PDF (1.1 MB) | EPUB
  • 150 Views
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Original Research

Article
Eicosanoids metabolized through LOX distinguish asthma–COPD overlap from COPD by metabolomics study
Chuanxu Cai, Xiqing Bian, Mingshan Xue, Xiaoqing Liu, Haisheng Hu, Jingxian Wang, Song Guo Zheng, Baoqing Sun & Jian-Lin Wu
Pages: 1769-1778
Published online: 24 Oct 2022
AbstractforEicosanoids metabolized through LOX distinguish asthma–COPD overlap from COPD by metabolomics study | Full Text | References | PDF (2 MB) | EPUB
  • 85 Views
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Open Access

Review

Article
Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease
Takudzwa Mkorombindo & Mark T Dransfield
Pages: 1779-1787
Published online: 07 Aug 2019
AbstractforMepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease | Full Text | References | PDF (594.5 KB) | EPUB
  • 185 Views
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Open Access

Clinical Trial Report

Article
Effect of tiotropium/olodaterol on sedentary and active time in patients with COPD: post hoc analysis of the VESUTO® study
Yoshiaki Minakata, Takashi Motegi, Jun Ueki, Yasuhiro Gon, Shuhei Nakamura, Tatsuhiko Anzai, Kazuto Hirata & Masakazu Ichinose
Pages: 1789-1801
Published online: 24 Oct 2022
AbstractforEffect of tiotropium/olodaterol on sedentary and active time in patients with COPD: post hoc analysis of the VESUTO® study | Full Text | References | PDF (4.7 MB) | EPUB
  • 91 Views
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Open Access

Original Research

Article
Forced expiratory volumes in 3 s is a sensitive clinical measure for assessment of bronchodilator reversibility in elderly Chinese with severe lung function impairment
Mingming Pan, Hongsheng Zhang & Tieying Sun
Pages: 1803-1811
Published online: 24 Oct 2022
AbstractforForced expiratory volumes in 3 s is a sensitive clinical measure for assessment of bronchodilator reversibility in elderly Chinese with severe lung function impairment | Full Text | References | PDF (1,008.8 KB) | EPUB
  • 61 Views
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Open Access
Article
Respiratory health and quality of life in young exclusive, habitual smokers - a comparison of waterpipe smokers, cigarette smokers and non-smokers
F I Hawari, N A Obeidat, M Abu Alhalawa, Z Al-Busaidi, B Amara, S Baddar, M Elhabiby & H Elkholy
Pages: 1813-1824
Published online: 13 Aug 2019
Abstractfor Respiratory health and quality of life in young exclusive, habitual smokers - a comparison of waterpipe smokers, cigarette smokers and non-smokers | Full Text | References | PDF (377.8 KB) | EPUB
  • 371 Views
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Open Access

Review

Article
Measuring and monitoring skeletal muscle function in COPD: current perspectives
Sarah Marklund, Kim-Ly Bui & Andre Nyberg
Pages: 1825-1838
Published online: 24 Oct 2022
AbstractforMeasuring and monitoring skeletal muscle function in COPD: current perspectives | Full Text | References | PDF (1.5 MB) | EPUB
  • 432 Views
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Open Access

Original Research

Article
Dual versus triple therapy in patients hospitalized for COPD in France: a claims data study
Faustine Dalon, Nicolas Roche, Manon Belhassen, Maëva Nolin, Hervé Pegliasco, Gaëtan Deslée, Bruno Housset, Philippe Devillier & Eric Van Ganse
Pages: 1839-1854
Published online: 24 Oct 2022
AbstractforDual versus triple therapy in patients hospitalized for COPD in France: a claims data study | Full Text | References | PDF (1.4 MB) | EPUB
  • 102 Views
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Open Access
Article
Contributions of cardiovascular risk and smoking to chronic obstructive pulmonary disease (COPD)-related changes in brain structure and function
Catherine A Spilling, Mohani-Preet K Bajaj, Daniel R Burrage, Sachelle Ruickbie, N Jade Thai, Emma H Baker, Paul W Jones, Thomas R Barrick & James W Dodd
Pages: 1855-1866
Published online: 21 Aug 2019
AbstractforContributions of cardiovascular risk and smoking to chronic obstructive pulmonary disease (COPD)-related changes in brain structure and function | Full Text | References | PDF (1.3 MB) | EPUB
  • 224 Views
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Open Access
Article
Effect of PD-1 inhibitor on exhaled nitric oxide and pulmonary function in non-small cell lung cancer patients with and without COPD
Yuzo Suzuki, Naoki Inui, Masato Karayama, Shiro Imokawa, Takashi Yamada, Koushi Yokomura, Kazuhiro Asada, Hideki Kusagaya, Yusuke Kaida, Hiroyuki Matsuda, Naoki Koshimizu, Mikio Toyoshima, Masafumi Masuda, Hiroshi Hayakawa, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura & Takafumi Suda
Pages: 1867-1877
Published online: 21 Aug 2019
AbstractforEffect of PD-1 inhibitor on exhaled nitric oxide and pulmonary function in non-small cell lung cancer patients with and without COPD | Full Text | References | PDF (1.4 MB) | EPUB
  • 102 Views
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Open Access
Article
Bacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD
Bruno Balbi, Claudia Sangiorgi, Isabella Gnemmi, Ilaria Ferrarotti, Davide Vallese, Elena Paracchini, Lorena Delle Donne, Luciano Corda, Paolo Baderna, Angelo Corsico, Mauro Carone, Paola Brun, Francesco Cappello, Fabio LM Ricciardolo, Paolo Ruggeri, Sharon Mumby, Ian M Adcock, Gaetano Caramori & Antonino Di Stefano
Pages: 1879-1893
Published online: 24 Oct 2022
AbstractforBacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD | Full Text | References | PDF (2.5 MB) | EPUB
  • 118 Views
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Open Access
Article
Are pulmonologists well aware of planning safe air travel for patients with COPD? The SAFCOP study
Begüm Ergan, Hüseyin Arıkan & Metin Akgün
Pages: 1895-1900
Published online: 22 Aug 2019
AbstractforAre pulmonologists well aware of planning safe air travel for patients with COPD? The SAFCOP study | Full Text | References | PDF (385.4 KB) | EPUB
  • 90 Views
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Open Access
Article
External validation of the PUMA COPD diagnostic questionnaire in a general practice sample and the PLATINO study population
Maria Victorina Lopez Varela, Maria Montes de Oca, Fernando C Wehrmeister, Cecilia Rodriguez, Larissa Ramirez, Ana Menezes & On behalf of the PLATINO team
Pages: 1901-1911
Published online: 26 Aug 2019
AbstractforExternal validation of the PUMA COPD diagnostic questionnaire in a general practice sample and the PLATINO study population | Full Text | References | PDF (337.8 KB) | EPUB
  • 182 Views
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Open Access
Article
Does chronic obstructive pulmonary disease increase the risk of prostate cancer? A nationwide population-based study
Wen-Lin Hsu, Hung-Yi Chen, Fung-Wei Chang & Ren-Jun Hsu
Pages: 1913-1921
Published online: 22 Aug 2019
AbstractforDoes chronic obstructive pulmonary disease increase the risk of prostate cancer? A nationwide population-based study | Full Text | References | PDF (547 KB) | EPUB
  • 89 Views
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Open Access
Article
Systemic inflammation and the effects of short-term antibiotic treatment for PPM positive patients with stable COPD
Jin-Xiang Wang, Hui-Qiao Li, Fang Zhang & Wei Ning
Pages: 1923-1932
Published online: 23 Aug 2019
AbstractforSystemic inflammation and the effects of short-term antibiotic treatment for PPM positive patients with stable COPD | Full Text | References | PDF (2 MB) | EPUB
  • 50 Views
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Open Access
Article
Circulating syndecan-1 as a novel biomarker relates to lung function, systemic inflammation, and exacerbation in COPD
Diandian Li, Yanqiu Wu, Shujin Guo, Jiangyue Qin, Mei Feng, Yunfei An, Junlong Zhang, Yanping Li, Shuguang Xiong, Hui Zhou, Qianglin Zeng, Lei Chen & Fuqiang Wen
Pages: 1933-1941
Published online: 28 Aug 2019
AbstractforCirculating syndecan-1 as a novel biomarker relates to lung function, systemic inflammation, and exacerbation in COPD | Full Text | References | PDF (2.2 MB) | EPUB
  • 93 Views
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Article
A survey exploring knowledge and beliefs about electronic cigarettes between health care providers and the general population in Egypt
Ibrahim Dwedar, Dina Ruby & Aya Mostafa
Pages: 1943-1950
Published online: 30 Aug 2019
AbstractforA survey exploring knowledge and beliefs about electronic cigarettes between health care providers and the general population in Egypt | Full Text | References | PDF (242.5 KB) | EPUB
  • 294 Views
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Article
SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
Rafael Acero Colmenares & Carlos Ernesto Lombo Moreno
Pages: 1951-1958
Published online: 29 Aug 2019
AbstractforSaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude | Full Text | References | PDF (726.8 KB) | EPUB
  • 84 Views
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Open Access
Article
Association between chronic obstructive pulmonary disease and activity of daily living among oldest-old in China: based on Chinese Longitudinal Health Longevity Survey
Miao Liu, Yanhong Yue & Yao He
Pages: 1959-1966
Published online: 29 Aug 2019
AbstractforAssociation between chronic obstructive pulmonary disease and activity of daily living among oldest-old in China: based on Chinese Longitudinal Health Longevity Survey | Full Text | References | PDF (235.4 KB) | EPUB
  • 74 Views
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Open Access
Article
Simple standard equation for daily step count in Japanese patients with chronic obstructive pulmonary disease
Masanori Nakanishi, Yoshiaki Minakata, Rie Tanaka, Hisatoshi Sugiura, Hikaru Kuroda, Makoto Yoshida & Nobuyuki Yamamoto
Pages: 1967-1977
Published online: 24 Oct 2022
AbstractforSimple standard equation for daily step count in Japanese patients with chronic obstructive pulmonary disease | Full Text | References | PDF (1.8 MB) | EPUB
  • 90 Views
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Article
Progression of physical inactivity in COPD patients: the effect of time and climate conditions – a multicenter prospective cohort study
Afroditi K Boutou, Yogini Raste, Heleen Demeyer, Thierry Troosters, Michael I Polkey, Ioannis Vogiatzis, Zafeiris Louvaris, Roberto A Rabinovich, Thys van der Molen, Judith Garcia-Aymerich, Nicholas S Hopkinson & On behalf of the PROactive consortium
Pages: 1979-1992
Published online: 03 Sep 2019
AbstractforProgression of physical inactivity in COPD patients: the effect of time and climate conditions – a multicenter prospective cohort study | Full Text | References | PDF (2 MB) | EPUB
  • 218 Views
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Open Access

Perspectives

Article
Diagnosis and management of chronic obstructive pulmonary disease in Serbia: an expert group position statement
Marija Vukoja, Ivan Kopitovic, Zorica Lazic, Branislava Milenkovic, Ivana Stankovic, Biljana Zvezdin, Aleksandra Dudvarski Ilic, Ivan Cekerevac, Miodrag Vukcevic, Vladimir Zugic & Sanja Hromis
Pages: 1993-2002
Published online: 02 Sep 2019
AbstractforDiagnosis and management of chronic obstructive pulmonary disease in Serbia: an expert group position statement | Full Text | References | PDF (1.7 MB) | EPUB
  • 194 Views
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Open Access

Original Research

Article
Trends in prescriptions and costs of inhaled medications in chronic obstructive pulmonary disease: a 19-year population-based study from Canada
Hamid Tavakoli, Kate M Johnson, J Mark FitzGerald, Don D Sin, Andrea S Gershon, Tetyana Kendzerska, Mohsen Sadatsafavi & On behalf of the Canadian Respiratory Research Network
Pages: 2003-2013
Published online: 03 Sep 2019
AbstractforTrends in prescriptions and costs of inhaled medications in chronic obstructive pulmonary disease: a 19-year population-based study from Canada | Full Text | References | PDF (1.1 MB) | EPUB
  • 168 Views
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Open Access
Article
Disruption of histidine and energy homeostasis in chronic obstructive pulmonary disease
Wenqi Diao, Wassim W Labaki, MeiLan K Han, Larisa Yeomans, Yihan Sun, Zyad Smiley, Jae Hyun Kim, Cora McHugh, Pingchao Xiang, Ning Shen, Xiaoyan Sun, Chenxia Guo, Ming Lu, Theodore J Standiford, Bei He & Kathleen A Stringer
Pages: 2015-2025
Published online: 03 Sep 2019
AbstractforDisruption of histidine and energy homeostasis in chronic obstructive pulmonary disease | Full Text | References | PDF (2.5 MB) | EPUB
  • 143 Views
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Open Access
Article
Evaluation of isokinetic muscle strength of upper limb and the relationship with pulmonary function and respiratory muscle strength in stable COPD patients
Xiaodan Liu, Peijun Li, Zhenwei Wang, Yufan Lu, Ning Li, Lu Xiao, Hongxia Duan, Zhengrong Wang, Jian Li, Chunlei Shan & Weibing Wu
Pages: 2027-2036
Published online: 24 Oct 2022
AbstractforEvaluation of isokinetic muscle strength of upper limb and the relationship with pulmonary function and respiratory muscle strength in stable COPD patients | Full Text | References | PDF (389.6 KB) | EPUB
  • 285 Views
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Open Access
Article
Risk of chronic obstructive pulmonary disease in healthy individuals with high C-reactive protein levels by smoking status: a population-based cohort study in Korea
Seong Yong Lim, Di Zhao, Eliseo Guallar, Yoosoo Chang, Seungho Ryu, Juhee Cho & Jung Yeon Shim
Pages: 2037-2046
Published online: 03 Sep 2019
AbstractforRisk of chronic obstructive pulmonary disease in healthy individuals with high C-reactive protein levels by smoking status: a population-based cohort study in Korea | Full Text | References | PDF (1.6 MB) | EPUB
  • 65 Views
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Open Access
Article
Evaluation of rescue medication use and medication adherence receiving umeclidinium/vilanterol versus tiotropium bromide/olodaterol
Chad Moretz, Lindsay GS Bengtson, Lucie Sharpsten, Eleena Koep, Lisa Le, Junliang Tong, Richard H Stanford, Beth Hahn & Riju Ray
Pages: 2047-2060
Published online: 04 Sep 2019
AbstractforEvaluation of rescue medication use and medication adherence receiving umeclidinium/vilanterol versus tiotropium bromide/olodaterol | Full Text | References | PDF (2.3 MB) | EPUB
  • 90 Views
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Open Access

Erratum

Correction
Effect of tiotropium/olodaterol on sedentary and active time in patients with COPD: post hoc analysis of the VESUTO® study [Erratum]
Pages: 2061-2064
Published online: 03 Sep 2019
First Page PreviewforEffect of tiotropium/olodaterol on sedentary and active time in patients with COPD: post hoc analysis of the VESUTO® study [Erratum] | Full Text | PDF (3.5 MB) | EPUB
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Open Access

Review

Article
Assessing pulmonary hypertension in COPD. Is there a role for computed tomography?
Florence Coste, Ilyes Benlala, Gaël Dournes, Pierre-Olivier Girodet, François Laurent & Patrick Berger
Pages: 2065-2079
Published online: 04 Sep 2019
AbstractforAssessing pulmonary hypertension in COPD. Is there a role for computed tomography? | Full Text | References | PDF (1.3 MB) | EPUB
  • 154 Views
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Original Research

Article
Association among genetic polymorphisms of GSTP1, HO-1, and SOD-3 and chronic obstructive pulmonary disease susceptibility
Yong Du, Hui Zhang, Yan Xu, Yi Ding, Xuru Chen, Zhoufang Mei, Heyuan Ding & Zhijun Jie
Pages: 2081-2088
Published online: 06 Sep 2019
AbstractforAssociation among genetic polymorphisms of GSTP1, HO-1, and SOD-3 and chronic obstructive pulmonary disease susceptibility | Full Text | References | PDF (303 KB) | EPUB
  • 138 Views
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Open Access
Article
An analysis of the degree of concordance among international guidelines regarding alpha-1 antitrypsin deficiency
Amy Attaway, Uddalak Majumdar, Robert A Sandhaus, Amy S Nowacki & James K Stoller
Pages: 2089-2101
Published online: 05 Sep 2019
AbstractforAn analysis of the degree of concordance among international guidelines regarding alpha-1 antitrypsin deficiency | Full Text | References | PDF (1.1 MB) | EPUB
  • 104 Views
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Open Access
Article
CYP2B6 genetic polymorphisms influence chronic obstructive pulmonary disease susceptibility in the Hainan population
Yipeng Ding, Quanni Li, Qiong Feng, Dongchuan Xu, Cibing Wu, Jie Zhao, Xiaoli Zhou, Yixiu Yang, Huan Niu, Ping He & Lihua Xing
Pages: 2103-2115
Published online: 05 Sep 2019
AbstractforCYP2B6 genetic polymorphisms influence chronic obstructive pulmonary disease susceptibility in the Hainan population | Full Text | References | PDF (947.8 KB) | EPUB
  • 73 Views
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Letter

Article
Letter to the editor: “Nasal high-flow versus non-invasive ventilation in patients with chronic hypercapnic COPD” [Letter]
J Elshof & ML Duiverman
Pages: 2117-2118
Published online: 06 Sep 2019
CitationforLetter to the editor: “Nasal high-flow versus non-invasive ventilation in patients with chronic hypercapnic COPD” [Letter] | Full Text | References | PDF (178.9 KB) | EPUB
  • 82 Views
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Response to Letter

Article
Response to the letter to the editor “Nasal high-flow versus non-invasive ventilation in patients with chronic hypercapnic COPD” [Response to letter]
Hubert Wirtz, David Petroff & Jens Bräunlich
Pages: 2119-2120
Published online: 09 Sep 2019
CitationforResponse to the letter to the editor “Nasal high-flow versus non-invasive ventilation in patients with chronic hypercapnic COPD” [Response to letter] | Full Text | References | PDF (313.1 KB) | EPUB
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Original Research

Article
Economic impact of delaying initiation with multiple-inhaler maintenance triple therapy in Spanish patients with chronic obstructive pulmonary disease
Antoni Sicras Mainar, Alicia Huerta, Ruth Navarro Artieda, Eduard Monsó, Sarah H Landis & Afisi S Ismaila
Pages: 2121-2129
Published online: 12 Sep 2019
AbstractforEconomic impact of delaying initiation with multiple-inhaler maintenance triple therapy in Spanish patients with chronic obstructive pulmonary disease | Full Text | References | PDF (508.5 KB) | EPUB
  • 86 Views
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Open Access

Letter

Article
Poor outcome of laparoscopic cholecystectomy in patients with COPD: how determinant it is? [Letter]
Subrata Kumar Singha, Habib MR Karim & Antonio Esquinas
Pages: 2131-2132
Published online: 24 Oct 2022
CitationforPoor outcome of laparoscopic cholecystectomy in patients with COPD: how determinant it is? [Letter] | Full Text | References | PDF (176.3 KB) | EPUB
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Response to Letter

Article
Poor outcome of laparoscopic cholecystectomy in patients with COPD: how determinant it is? [Response to Letter]
Kuang-Ming Liao & Chung-Han Ho
Pages: 2133-2134
Published online: 13 Sep 2019
CitationforPoor outcome of laparoscopic cholecystectomy in patients with COPD: how determinant it is? [Response to Letter] | Full Text | PDF (159.8 KB) | EPUB
  • 55 Views
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Original Research

Article
Impact of symptom variability on clinical outcomes in COPD: analysis of a longitudinal cohort
Mi-Ae Kim, Min-Kang Suh, Jisoo Park, Jung-Hyun Kim, Tae-Hoon Kim, Eun Kyung Kim, Yeon-Mok Oh, Sang-Do Lee & Ji-Hyun Lee
Pages: 2135-2144
Published online: 20 Sep 2019
AbstractforImpact of symptom variability on clinical outcomes in COPD: analysis of a longitudinal cohort | Full Text | References | PDF (512.2 KB) | EPUB
  • 60 Views
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Article
Roundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis
Yuan-Zhen Lin, Xiao-Ning Zhong, Xin Chen, Yi Liang, Hui Zhang & Dong-Lan Zhu
Pages: 2145-2162
Published online: 18 Sep 2019
AbstractforRoundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis | Full Text | References | PDF (9.4 MB) | EPUB
  • 122 Views
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Article
Prevalence of cardiac comorbidities, and their underdetection and contribution to exertional symptoms in COPD: results from the COSYCONET cohort
Peter Alter, Barbara A Mayerhofer, Kathrin Kahnert, Henrik Watz, Benjamin Waschki, Stefan Andreas, Frank Biertz, Robert Bals, Claus F Vogelmeier & Rudolf A Jörres
Pages: 2163-2172
Published online: 24 Oct 2022
AbstractforPrevalence of cardiac comorbidities, and their underdetection and contribution to exertional symptoms in COPD: results from the COSYCONET cohort | Full Text | References | PDF (706.3 KB) | EPUB
  • 205 Views
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Open Access
Article
Imidafenacin, An Orally Active Muscarinic Receptor Antagonist, Improves Pulmonary Function In Patients With Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled 3×3 Crossover Phase II Trial
Kentaro Machida, Tomotaka Kawayama, Masaharu Kinoshita, Masakazu Ichinose, Tohru Tsuda, Shohei Takata, Hiroshi Koto, Makoto Yoshida, Yoshinori Ashihara, Masaru Kawashima, Hideaki Suna & Hiromasa Inoue
Pages: 2175-2184
Published online: 19 Sep 2019
AbstractforImidafenacin, An Orally Active Muscarinic Receptor Antagonist, Improves Pulmonary Function In Patients With Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled 3×3 Crossover Phase II Trial | Full Text | References | PDF (5.3 MB) | EPUB
  • 69 Views
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Review

Article
A Framework For Step Down Or Therapeutic Re-Organization For Withdrawal Of Inhaled Corticosteroids In Selected Patients With COPD: A Proposal For COPD Management
Claudio Micheletto, Fulvio Braido, Marco Contoli, Fabiano Di Marco & Pierachille Santus
Pages: 2185-2193
Published online: 24 Oct 2022
AbstractforA Framework For Step Down Or Therapeutic Re-Organization For Withdrawal Of Inhaled Corticosteroids In Selected Patients With COPD: A Proposal For COPD Management | Full Text | References | PDF (2.4 MB) | EPUB
  • 68 Views
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Original Research

Article
Assessment Of Changes In Regional Xenon-Ventilation, Perfusion, And Ventilation-Perfusion Mismatch Using Dual-Energy Computed Tomography After Pharmacological Treatment In Patients With Chronic Obstructive Pulmonary Disease: Visual And Quantitative Analysis
Hye Jeon Hwang, Sang Min Lee, Joon Beom Seo, Jae Seung Lee, Namkug Kim, Cherry Kim, Sang Young Oh & Sei Won Lee
Pages: 2195-2203
Published online: 25 Sep 2019
AbstractforAssessment Of Changes In Regional Xenon-Ventilation, Perfusion, And Ventilation-Perfusion Mismatch Using Dual-Energy Computed Tomography After Pharmacological Treatment In Patients With Chronic Obstructive Pulmonary Disease: Visual And Quantitative Analysis | Full Text | References | PDF (4.5 MB) | EPUB
  • 200 Views
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Article
Chronic Obstructive Pulmonary Disease In Aboriginal Patients Of The Northern Territory Of Australia: A Landscape Perspective
Subash S Heraganahally, Sanjiwika L Wasgewatta, Kelly McNamara, Carla C Eisemberg, Richard C Budd, Sumit Mehra & Dimitar Sajkov
Pages: 2205-2217
Published online: 24 Oct 2022
AbstractforChronic Obstructive Pulmonary Disease In Aboriginal Patients Of The Northern Territory Of Australia: A Landscape Perspective | Full Text | References | PDF (2.6 MB) | EPUB
  • 687 Views
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Review

Article
Inhaled Corticosteroids And Risk Of Tuberculosis In Patients With Obstructive Lung Diseases: A Systematic Review And Meta-Analysis Of Non-randomized Studies
Giorgio Castellana, Marco Castellana, Carlo Castellana, Giuseppe Castellana, Emanuela Resta, Mauro Carone & Onofrio Resta
Pages: 2219-2227
Published online: 24 Oct 2022
AbstractforInhaled Corticosteroids And Risk Of Tuberculosis In Patients With Obstructive Lung Diseases: A Systematic Review And Meta-Analysis Of Non-randomized Studies | Full Text | References | PDF (3.1 MB) | EPUB
  • 159 Views
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Perspectives

Article
Time To Revise COPD Treatment Algorithm
Kazuto Matsunaga, Keiji Oishi, Marc Miravitlles & Antonio Anzueto
Pages: 2229-2234
Published online: 27 Sep 2019
AbstractforTime To Revise COPD Treatment Algorithm | Full Text | References | PDF (3 MB) | EPUB
  • 175 Views
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Original Research

Article
National Trends In Kidney, Heart And Liver Transplants Among Patients With And Without Chronic Obstructive Pulmonary Disease In Spain (2001–2015)
Javier de Miguel-Díez, Rodrigo Jiménez-García, Valentín Hernández-Barrera, José M de Miguel-Yanes, Manuel Méndez-Bailón & Ana López-de-Andres
Pages: 2235-2243
Published online: 24 Oct 2022
AbstractforNational Trends In Kidney, Heart And Liver Transplants Among Patients With And Without Chronic Obstructive Pulmonary Disease In Spain (2001–2015) | Full Text | References | PDF (303.6 KB) | EPUB
  • 66 Views
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Article
Temporal Trends Of Pharmacologic Therapies For Patients With Chronic Obstructive Pulmonary Disease In Alberta, Canada
Dat T Tran, Ilke Akpinar, Irvin Mayers, Tatiana Makhinova & Philip Jacobs
Pages: 2245-2256
Published online: 26 Sep 2019
AbstractforTemporal Trends Of Pharmacologic Therapies For Patients With Chronic Obstructive Pulmonary Disease In Alberta, Canada | Full Text | References | PDF (2.7 MB) | EPUB
  • 80 Views
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Article
Amino Acid-Based Metabolic Indexes Identify Patients With Chronic Obstructive Pulmonary Disease And Further Discriminates Patients In Advanced BODE Stages
Wei-Ke Kuo, Yu-Chih Liu, Chien-Ming Chu, Chung-Ching Hua, Chih-Yu Huang, Min-Hui Liu & Chao-Hung Wang
Pages: 2257-2266
Published online: 30 Sep 2019
AbstractforAmino Acid-Based Metabolic Indexes Identify Patients With Chronic Obstructive Pulmonary Disease And Further Discriminates Patients In Advanced BODE Stages | Full Text | References | PDF (1.6 MB) | EPUB
  • 87 Views
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Article
Evaluation Of HHIP Polymorphisms And Their Relationship With Chronic Obstructive Pulmonary Disease Phenotypes
Thiago Prudente Bártholo, Luis Cristovão Porto, Roberto Pozzan, Adriana Nascimento & Claudia Henrique Da Costa
Pages: 2267-2272
Published online: 24 Oct 2022
AbstractforEvaluation Of HHIP Polymorphisms And Their Relationship With Chronic Obstructive Pulmonary Disease Phenotypes | Full Text | References | PDF (545 KB) | EPUB
  • 71 Views
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Article
Impact Of Underlying Pulmonary Diseases On Treatment Outcomes In Early-Stage Non-Small Cell Lung Cancer Treated With Definitive Radiotherapy
Hakyoung Kim, Hongseok Yoo, Hongryull Pyo, Yong Chan Ahn, Jae Myoung Noh, Sang Gyu Ju, Woojin Lee, Byoungsuk Park, Jin Man Kim, Noeul Kang, Sun Hye Shin, Man Pyo Chung, Sumin Shin, Hye Seung Kim, Minsu Park & Hye Yun Park
Pages: 2273-2281
Published online: 04 Oct 2019
AbstractforImpact Of Underlying Pulmonary Diseases On Treatment Outcomes In Early-Stage Non-Small Cell Lung Cancer Treated With Definitive Radiotherapy | Full Text | References | PDF (1.9 MB) | EPUB
  • 91 Views
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Article
Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans
Yanyan Xu, Tsuneo Yamashiro, Hiroshi Moriya, Shun Muramatsu & Sadayuki Murayama
Pages: 2283-2290
Published online: 08 Oct 2019
AbstractforQuantitative Emphysema Measurement On Ultra-High-Resolution CT Scans | Full Text | References | PDF (8.4 MB) | EPUB
  • 152 Views
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Article
Benefits of different intensities of pulmonary rehabilitation for patients with moderate-to-severe COPD according to the GOLD stage: a prospective, multicenter, single-blinded, randomized, controlled trial
Guo Xia He, Ning Li, Lei Ren, Hong Hua Shen, Ning Liao, Jian Jun Wen, Yi Min Xu, Jing Wang & Qing Yun Li
Pages: 2291-2304
Published online: 08 Oct 2019
AbstractforBenefits of different intensities of pulmonary rehabilitation for patients with moderate-to-severe COPD according to the GOLD stage: a prospective, multicenter, single-blinded, randomized, controlled trial | Full Text | References | PDF (581.2 KB) | EPUB
  • 414 Views
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Article
Pharmacokinetics and safety of revefenacin in subjects with impaired renal or hepatic function
Marie T Borin, Arthur Lo, Chris N Barnes, Srikanth Pendyala & David L Bourdet
Pages: 2305-2318
Published online: 24 Oct 2022
AbstractforPharmacokinetics and safety of revefenacin in subjects with impaired renal or hepatic function | Full Text | References | PDF (3.8 MB) | EPUB
  • 100 Views
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Article
Overexpression Of hsa-miR-664a-3p Is Associated With Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease Via Targeting FHL1
Shan Zhong, Chengshui Chen, Naijia Liu, Li Yang, Zhangli Hu, Pengfei Duan, Diquan Shuai, Qingying Zhang & Yun Wang
Pages: 2319-2329
Published online: 09 Oct 2019
AbstractforOverexpression Of hsa-miR-664a-3p Is Associated With Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease Via Targeting FHL1 | Full Text | References | PDF (7.1 MB) | EPUB
  • 132 Views
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Article
The Difficulty Of Improving Quality Of Life In COPD Patients With Depression And Associated Factors
Jeong Uk Lim, Chan Kwon Park, Tae-Hyung Kim, An-Soo Jang, Yong Bum Park, Chin Kook Rhee, Ki Suck Jung, Kwang Ha Yoo, Won-Yeon Lee & Hyoung Kyu Yoon
Pages: 2331-2341
Published online: 09 Oct 2019
AbstractforThe Difficulty Of Improving Quality Of Life In COPD Patients With Depression And Associated Factors | Full Text | References | PDF (2.9 MB) | EPUB
  • 346 Views
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Clinical Trial Report

Case Report
Improvement In Self-Reported Physical Functioning With Tiotropium/Olodaterol In Central And Eastern European COPD Patients
Arschang Valipour, Michael Tamm, Jana Kociánová, Valentina Bayer, Maria Sanzharovskaya, Alexey Medvedchikov, Monika Haaksma-Herczegh, János Mucsi, Zvi Fridlender, Claudia Toma, Andrey Belevskiy, Bohumil Matula & Jurij Šorli
Pages: 2343-2354
Published online: 11 Oct 2019
AbstractforImprovement In Self-Reported Physical Functioning With Tiotropium/Olodaterol In Central And Eastern European COPD Patients | Full Text | References | PDF (2.7 MB) | EPUB
  • 91 Views
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Original Research

Article
Association between airflow limitation severity and reduced bone mineral density in Japanese men
Kazuhiko Watanabe, Ayumi Onoue, Kenichi Kubota, Noritaka Higashi, Toshinari Hayashi, Tohru Tsuda & Hisamitsu Omori
Pages: 2355-2363
Published online: 16 Oct 2019
AbstractforAssociation between airflow limitation severity and reduced bone mineral density in Japanese men | Full Text | References | PDF (803.4 KB) | EPUB
  • 68 Views
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Article
Nebulized Colistin And Continuous Cyclic Azithromycin In Severe COPD Patients With Chronic Bronchial Infection Due To Pseudomonas aeruginosa: A Retrospective Cohort Study
Concepción Montón, Elena Prina, Xavier Pomares, Jose R Cugat, Antonio Casabella, Joan Carles Oliva, Miguel Gallego & Eduard Monsó
Pages: 2365-2373
Published online: 17 Oct 2019
AbstractforNebulized Colistin And Continuous Cyclic Azithromycin In Severe COPD Patients With Chronic Bronchial Infection Due To Pseudomonas aeruginosa: A Retrospective Cohort Study | Full Text | References | PDF (2.6 MB) | EPUB
  • 122 Views
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Open Access

Corrigendum

Correction
Progression Of Physical Inactivity In COPD Patients: The Effect Of Time And Climate Conditions – A Multicenter Prospective Cohort Study [Corrigendum]
Page: 2375
Published online: 18 Oct 2019
CitationforProgression Of Physical Inactivity In COPD Patients: The Effect Of Time And Climate Conditions – A Multicenter Prospective Cohort Study [Corrigendum] | Full Text | PDF (153.1 KB) | EPUB
  • 53 Views
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Original Research

Article
Prevalence Of Chronic Hypercapnia In Severe Chronic Obstructive Pulmonary Disease: Data From The HOmeVent Registry
Michael Dreher, Pierre-Charles Neuzeret, Wolfram Windisch, Dagmar Martens, Gerhard Hoheisel, Andreas Gröschel, Holger Woehrle, Thomas Fetsch, Andrea Graml & Thomas Köhnlein
Pages: 2377-2384
Published online: 18 Oct 2019
AbstractforPrevalence Of Chronic Hypercapnia In Severe Chronic Obstructive Pulmonary Disease: Data From The HOmeVent Registry | Full Text | References | PDF (411.3 KB) | EPUB
  • 280 Views
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Article
ST2 Predicts Mortality In Patients With Acute Hypercapnic Respiratory Failure Treated With Noninvasive Positive Pressure Ventilation
Brynja Jónsdóttir, Marie Ziebell Severinsen, Fredrik von Wowern, Carmen San Miguel, Jens P Goetze & Olle Melander
Pages: 2385-2393
Published online: 23 Oct 2019
AbstractforST2 Predicts Mortality In Patients With Acute Hypercapnic Respiratory Failure Treated With Noninvasive Positive Pressure Ventilation | Full Text | References | PDF (1.4 MB) | EPUB
  • 76 Views
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Article
External Validation Of The Updated ADO Score In COPD Patients From The Birmingham COPD Cohort
Spencer J Keene, Rachel E Jordan, Frits ME Franssen, Frank de Vries, James Martin, Alice Sitch, Alice Margaret Turner, Andrew P Dickens, David Fitzmaurice & Peymane Adab
Pages: 2395-2407
Published online: 24 Oct 2019
AbstractforExternal Validation Of The Updated ADO Score In COPD Patients From The Birmingham COPD Cohort | Full Text | References | PDF (3.3 MB) | EPUB
  • 79 Views
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Article
The Burden Of Chronic Obstructive Pulmonary Disease (COPD) In Finland: Impact Of Disease Severity And Eosinophil Count On Healthcare Resource Utilization
Arja Viinanen, Mariann I Lassenius, Iiro Toppila, Antti Karlsson, Lauri Veijalainen, Juhana J Idänpään-Heikkilä & Tarja Laitinen
Pages: 2409-2421
Published online: 25 Oct 2019
AbstractforThe Burden Of Chronic Obstructive Pulmonary Disease (COPD) In Finland: Impact Of Disease Severity And Eosinophil Count On Healthcare Resource Utilization | Full Text | References | PDF (613.8 KB) | EPUB
  • 109 Views
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Review

Review Article
An Oral Whole-Cell Killed Nontypeable Haemophilus influenzae Immunotherapeutic For The Prevention Of Acute Exacerbations Of Chronic Airway Disease
Robert L Clancy & Allan W Cripps
Pages: 2423-2431
Published online: 25 Oct 2019
AbstractforAn Oral Whole-Cell Killed Nontypeable Haemophilus influenzae Immunotherapeutic For The Prevention Of Acute Exacerbations Of Chronic Airway Disease | Full Text | References | PDF (1.9 MB) | EPUB
  • 80 Views
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Original Research

Article
Low FEV1 Is Associated With Increased Risk Of Cachexia In COPD Patients
Amin Mokari-Yamchi, Masoumeh Jabbari, Akbar Sharifi, Meisam Barati & Sorayya Kheirouri
Pages: 2433-2440
Published online: 31 Oct 2019
AbstractforLow FEV1 Is Associated With Increased Risk Of Cachexia In COPD Patients | Full Text | References | PDF (365.7 KB) | EPUB
  • 161 Views
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Article
Influence Of Socioeconomic Deprivation On Short- And Long-Term Outcomes Of Home-Based Pulmonary Rehabilitation In Patients With Chronic Obstructive Pulmonary Disease
Jean-Marie Grosbois, Justine Heluain-Robiquet, François Machuron, Gaelle Terce, Cécile Chenivesse, Benoit Wallaert & Olivier Le Rouzic
Pages: 2441-2449
Published online: 31 Oct 2019
AbstractforInfluence Of Socioeconomic Deprivation On Short- And Long-Term Outcomes Of Home-Based Pulmonary Rehabilitation In Patients With Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (6.8 MB) | EPUB
  • 218 Views
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Article
A Cross-Sectional Study Assessing Appropriateness Of Inhaled Corticosteroid Treatment In Primary And Secondary Care Patients With COPD In Sweden
Johanna Sulku, Christer Janson, Håkan Melhus, Andrei Malinovschi, Björn Ställberg, Kristina Bröms, Marieann Högman, Karin Lisspers, Margareta Hammarlund-Udenaes & Elisabet I Nielsen
Pages: 2451-2460
Published online: 05 Nov 2019
AbstractforA Cross-Sectional Study Assessing Appropriateness Of Inhaled Corticosteroid Treatment In Primary And Secondary Care Patients With COPD In Sweden | Full Text | References | PDF (4.3 MB) | EPUB
  • 88 Views
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Article
Quadriceps Endurance Increases Following Cycling Exercise With Non-Invasive Ventilation In Moderate-To-Severe COPD Patients. A Non-Randomized Controlled Study
Pierre Labeix, Mathieu Berger, Isabelle Court Fortune, Léonard Feasson, Samuel Verges & Frédéric Costes
Pages: 2461-2468
Published online: 05 Nov 2019
AbstractforQuadriceps Endurance Increases Following Cycling Exercise With Non-Invasive Ventilation In Moderate-To-Severe COPD Patients. A Non-Randomized Controlled Study | Full Text | References | PDF (1.9 MB) | EPUB
  • 72 Views
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Article
Clinical Features Of Women With COPD: Sex Differences In A Cross-Sectional Study In Spain (“The ESPIRAL-ES Study”)
Juan Antonio Trigueros, Juan Antonio Riesco, Bernardino Alcázar-Navarrete, Anna Campuzano & Joselín Pérez
Pages: 2469-2478
Published online: 05 Nov 2019
AbstractforClinical Features Of Women With COPD: Sex Differences In A Cross-Sectional Study In Spain (“The ESPIRAL-ES Study”) | Full Text | References | PDF (1.5 MB) | EPUB
  • 180 Views
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Article
Ultrasound Assessment Of Diaphragmatic Function During Acute Exacerbation Of Chronic Obstructive Pulmonary Disease: A Pilot Study
Sung Yoon Lim, Gajin Lim, Yeon Joo Lee, Young Jae Cho, Jong Sun Park, Ho Il Yoon, Jae Ho Lee & Choon-Taek Lee
Pages: 2479-2484
Published online: 07 Nov 2019
AbstractforUltrasound Assessment Of Diaphragmatic Function During Acute Exacerbation Of Chronic Obstructive Pulmonary Disease: A Pilot Study | Full Text | References | PDF (1 MB) | EPUB
  • 171 Views
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Article
Statistical Process Control Improves The Feasibility Of Remote Physiological Monitoring In Patients With Chronic Obstructive Pulmonary Disease
Christopher B Cooper, Worawan Sirichana, Eric V Neufeld, Michael Taylor, Xiaoyan Wang & Brett A Dolezal
Pages: 2485-2496
Published online: 13 Nov 2019
AbstractforStatistical Process Control Improves The Feasibility Of Remote Physiological Monitoring In Patients With Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (1.8 MB) | EPUB
  • 95 Views
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Article
The Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease
Mengqing Xiong, Weihua Hu, Minglin Dong, Meifang Wang, Junwen Chen, Hanzhong Xiong, Minhua Zhong, Yan Jiang, Dan Liu & Ke Hu
Pages: 2497-2505
Published online: 13 Nov 2019
AbstractforThe Screening Value Of ESS, SACS, BQ, And SBQ On Obstructive Sleep Apnea In Patients With Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (1.6 MB) | EPUB
  • 114 Views
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Article
Exercise Ameliorates Emphysema Of Cigarette Smoke-Induced COPD In Mice Through The Exercise-Irisin-Nrf2 Axis
Hiroaki Kubo, Kazuhisa Asai, Kazuya Kojima, Arata Sugitani, Yohkoh Kyomoto, Atsuko Okamoto, Kazuhiro Yamada, Naoki Ijiri, Tetsuya Watanabe, Kazuto Hirata & Tomoya Kawaguchi
Pages: 2507-2516
Published online: 24 Oct 2022
AbstractforExercise Ameliorates Emphysema Of Cigarette Smoke-Induced COPD In Mice Through The Exercise-Irisin-Nrf2 Axis | Full Text | References | PDF (2.5 MB) | EPUB
  • 176 Views
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Article
Blood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression
Ravi Lokwani, Peter AB Wark, Katherine J Baines, Michael Fricker, Daniel Barker & Jodie L Simpson
Pages: 2517-2525
Published online: 15 Nov 2019
AbstractforBlood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression | Full Text | References | PDF (2.4 MB) | EPUB
  • 108 Views
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Article
Improving Influenza Vaccination Coverage Among Patients With COPD: A Pilot Project
Andrew Li, Yiong-Huak Chan, Mei Fong Liew, Rakshya Pandey & Jason Phua
Pages: 2527-2533
Published online: 15 Nov 2019
AbstractforImproving Influenza Vaccination Coverage Among Patients With COPD: A Pilot Project | Full Text | References | PDF (840.2 KB) | EPUB
  • 225 Views
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Methodology

Article
Diagnosing Alpha-1-Antitrypsin Deficiency Using A PCR/Luminescence-Based Technology
Martina Veith, Andreas Klemmer, Iker Anton, Rachid El Hamss, Noelia Rapun, Sabina Janciauskiene, Viktor Kotke, Christian Herr, Robert Bals, Claus Franz Vogelmeier & Timm Greulich
Pages: 2535-2542
Published online: 18 Nov 2019
AbstractforDiagnosing Alpha-1-Antitrypsin Deficiency Using A PCR/Luminescence-Based Technology | Full Text | References | PDF (2.4 MB) | EPUB
  • 111 Views
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Original Research

Article
Impact Of Peak Oxygen Pulse On Patients With Chronic Obstructive Pulmonary Disease
Chih-Wei Wu, Po-Chun Hsieh, Mei-Chen Yang, I-Shiang Tzeng, Yao-Kuang Wu & Chou-Chin Lan
Pages: 2543-2551
Published online: 20 Nov 2019
AbstractforImpact Of Peak Oxygen Pulse On Patients With Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (1.3 MB) | EPUB
  • 120 Views
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Article
Positive Expiratory Pressure Therapy With And Without Oscillation And Hospital Length Of Stay For Acute Exacerbation Of Chronic Obstructive Pulmonary Disease
Stephen Milan, Praveen Bondalapati, Michael Megally, Eshan Patel, Pramil Vaghasia, Liam Gross, Elizabeth M Bachman, Puja Chadha & Jeremy A Weingarten
Pages: 2553-2561
Published online: 24 Oct 2022
AbstractforPositive Expiratory Pressure Therapy With And Without Oscillation And Hospital Length Of Stay For Acute Exacerbation Of Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (2 MB) | EPUB
  • 427 Views
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Article
Sputum Exosomal microRNAs Profiling Reveals Critical Pathways Modulated By Pseudomonas aeruginosa Colonization In Bronchiectasis
Yan Huang, Chun-lan Chen, Jing-jing Yuan, Hui-min Li, Xiao-rong Han, Rong-chang Chen, Wei-jie Guan & Nan-shan Zhong
Pages: 2563-2573
Published online: 22 Nov 2019
AbstractforSputum Exosomal microRNAs Profiling Reveals Critical Pathways Modulated By Pseudomonas aeruginosa Colonization In Bronchiectasis | Full Text | References | PDF (4.5 MB) | EPUB
  • 79 Views
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Article
Respiratory Mechanics and Diaphragmatic Dysfunction in COPD Patients Who Failed Non-Invasive Mechanical Ventilation
Alessandro Marchioni, Roberto Tonelli, Riccardo Fantini, Luca Tabbì, Ivana Castaniere, Francesco Livrieri, Sabrina Bedogni, Valentina Ruggieri, Lara Pisani, Stefano Nava & Enrico Clini
Pages: 2575-2585
Published online: 22 Nov 2019
AbstractforRespiratory Mechanics and Diaphragmatic Dysfunction in COPD Patients Who Failed Non-Invasive Mechanical Ventilation | Full Text | References | PDF (5 MB) | EPUB
  • 191 Views
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Expert Opinion

Article Commentary
Copper-Heparin Inhalation Therapy To Repair Emphysema: A Scientific Rationale
Rob Janssen, Emiel FM Wouters, Wim Janssens, Willeke F Daamen, Paul Hagedoorn, Hugo AJM de Wit, Jef Serré, Ghislaine Gayan-Ramirez, Frits ME Franssen, Niki L Reynaert, Jan H von der Thüsen & Henderik W Frijlink
Pages: 2587-2602
Published online: 25 Nov 2019
AbstractforCopper-Heparin Inhalation Therapy To Repair Emphysema: A Scientific Rationale | Full Text | References | PDF (4.7 MB) | EPUB
  • 125 Views
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Original Research

Article
Comprehensive Effects of Organized Education for Patients with Chronic Obstructive Pulmonary Disease
Jong Geol Jang, Jee Seon Kim, Jin Hong Chung, Kyeong Cheol Shin, June Hong Ahn, Mi Sook Lee, So Hee Bang, Da Yeong Park, Mee Jung Nam, Hyun Jung Jin & Kwan Ho Lee
Pages: 2603-2609
Published online: 24 Oct 2022
AbstractforComprehensive Effects of Organized Education for Patients with Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (503 KB) | EPUB
  • 135 Views
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Article
Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD
Nisha Kurian, Taylor S Cohen, Lisa Öberg, Erica De Zan, Gabriel Skogberg, Stefan Vollmer, Engin Baturcam, Petter Svanberg, Britta Bonn, Paul D Smith, Outi Vaarala & Danen M Cunoosamy
Pages: 2611-2624
Published online: 26 Nov 2019
AbstractforDual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD | Full Text | References | PDF (5.1 MB) | EPUB
  • 106 Views
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Article
Clinical And Economic Burden Of Eosinophilic COPD In A Large Retrospective US Cohort
Frank Trudo, Lee Kallenbach, Joseph Vasey, Yen Chung, Alan Wilk, Lukas Slipski, Dan O’Brien & Charlie Strange
Pages: 2625-2637
Published online: 26 Nov 2019
AbstractforClinical And Economic Burden Of Eosinophilic COPD In A Large Retrospective US Cohort | Full Text | References | PDF (4.9 MB) | EPUB
  • 105 Views
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Article
Prescription Status and Clinical Outcomes of Methylxanthines and Leukotriene Receptor Antagonists in Mild-to-Moderate Chronic Obstructive Pulmonary Disease
Jung-Kyu Lee, Chin Kook Rhee, Kyungjoo Kim, Seung Won Ra, Jae Ha Lee, Ki-Suck Jung, Kwang Ha Yoo, Yoo-Il Kim & Deog Kyeom Kim
Pages: 2639-2647
Published online: 27 Nov 2019
AbstractforPrescription Status and Clinical Outcomes of Methylxanthines and Leukotriene Receptor Antagonists in Mild-to-Moderate Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (1 MB) | EPUB
  • 131 Views
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Article
Development of a Standard Set of Outcome Domains and Proposed Measures for Chronic Obstructive Pulmonary Disease in Primary Care Physical Therapy Practice in the Netherlands: a Modified RAND/UCLA Appropriateness Method
Arie C Verburg, Simone A van Dulmen, Henri Kiers, Jan HL Ypinga, Maria WG Nijhuis-van der Sanden & Philip J van der Wees
Pages: 2649-2661
Published online: 28 Nov 2019
AbstractforDevelopment of a Standard Set of Outcome Domains and Proposed Measures for Chronic Obstructive Pulmonary Disease in Primary Care Physical Therapy Practice in the Netherlands: a Modified RAND/UCLA Appropriateness Method | Full Text | References | PDF (417.8 KB) | EPUB
  • 187 Views
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Article
Evaluation of the Characteristics of Asthma in Severe and Extremely Severe COPD
Feng-jia Chen, Geng-peng Lin, Xin-yan Huang, Yang-li Liu, Zhi-min Zeng & Yu-biao Guo
Pages: 2663-2671
Published online: 03 Dec 2019
AbstractforEvaluation of the Characteristics of Asthma in Severe and Extremely Severe COPD | Full Text | References | PDF (658.1 KB) | EPUB
  • 55 Views
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Article
The Attitudes of Pulmonologists Regarding Smoking Behavior of Their Patients with Advanced COPD: A Qualitative Research
K Mooren, GGH van der Linden, K Pool & Y Engels
Pages: 2673-2679
Published online: 29 Nov 2019
AbstractforThe Attitudes of Pulmonologists Regarding Smoking Behavior of Their Patients with Advanced COPD: A Qualitative Research | Full Text | References | PDF (348.1 KB) | EPUB
  • 223 Views
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Article
Cost-Effectiveness Of Once-Daily Single-Inhaler Triple Therapy In COPD: The IMPACT Trial
Afisi S Ismaila, Nancy Risebrough, Melanie Schroeder, Dhvani Shah, Alan Martin, Emma C Goodall, Kerigo Ndirangu, Gerard Criner, Mark Dransfield, David MG Halpin, MeiLan K Han & David A Lomas
Pages: 2681-2695
Published online: 29 Nov 2019
AbstractforCost-Effectiveness Of Once-Daily Single-Inhaler Triple Therapy In COPD: The IMPACT Trial | Full Text | References | PDF (2.1 MB) | EPUB
  • 245 Views
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Article
Erythromycin Prevents Elastin Peptide-Induced Emphysema and Modulates CD4+T Cell Responses in Mice
Shudan Tang, Tingting Ma, Hui Zhang, Jianquan Zhang, Xiaoning Zhong, Caimei Tan, Ye Qiu, Wen Zeng & Xin Feng
Pages: 2697-2709
Published online: 29 Nov 2019
AbstractforErythromycin Prevents Elastin Peptide-Induced Emphysema and Modulates CD4+T Cell Responses in Mice | Full Text | References | PDF (9.4 MB) | EPUB
  • 93 Views
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Article
Exacerbation Frequency And Eosinophil Counts Among Patients With COPD Currently Prescribed Triple Therapy
Victoria S Benson, Katie C Pascoe, James Siddall, Mark Small & Hana Müllerová
Pages: 2711-2723
Published online: 29 Nov 2019
AbstractforExacerbation Frequency And Eosinophil Counts Among Patients With COPD Currently Prescribed Triple Therapy | Full Text | References | PDF (467.3 KB) | EPUB
  • 104 Views
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Article
Clinical Outcomes Of Using Nebulized Budesonide As The Initial Treatment For Acute Exacerbations Of Chronic Obstructive Pulmonary Disease: A Post-Hoc Analysis
Jin-Ping Zheng, Jing Zhang, Li-Jun Ma, Ping Chen, Mao Huang, Xue-Mei Ou, Zi-Wen Zhao, Shu-Juan Jiang, Jie Cao & Wanzhen Yao
Pages: 2725-2731
Published online: 29 Nov 2019
AbstractforClinical Outcomes Of Using Nebulized Budesonide As The Initial Treatment For Acute Exacerbations Of Chronic Obstructive Pulmonary Disease: A Post-Hoc Analysis | Full Text | References | PDF (233.3 KB) | EPUB
  • 92 Views
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Clinical Trial Report

Case Report
Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation
Peter MA Calverley, Clive Page, Roberto W Dal Negro, Giovanni Fontana, Mario Cazzola, Arrigo F Cicero, Edoardo Pozzi & Jadwiga A Wedzicha
Pages: 2733-2744
Published online: 24 Oct 2022
AbstractforEffect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation | Full Text | References | PDF (617.4 KB) | EPUB
  • 211 Views
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Original Research

Article
Clinical Characteristics Of Patients With Asthma COPD Overlap (ACO) In Australian Primary Care
Gabriel Izbicki, Valerie Teo, Jenifer Liang, Grant M Russell, Anne E Holland, Nicholas A Zwar, Billie Bonevski, Ajay Mahal, Paula Eustace, Eldho Paul, Kirsten Phillips, Sally Wilson, Johnson George & Michael J Abramson
Pages: 2745-2752
Published online: 03 Dec 2019
AbstractforClinical Characteristics Of Patients With Asthma COPD Overlap (ACO) In Australian Primary Care | Full Text | References | PDF (688.3 KB) | EPUB
  • 149 Views
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Research Letter

Letter
Velocity Transfer Function In The Right Pulmonary Artery And Impaired Cardiopulmonary Reserve In COPD
Oleg F Sharifov, Thomas S Denney Jr, J Michael Wells, Gregory A Payne, Swati Gulati, Himanshu Gupta, Mark T Dransfield & Steven G Lloyd
Pages: 2753-2757
Published online: 24 Oct 2022
First Page PreviewforVelocity Transfer Function In The Right Pulmonary Artery And Impaired Cardiopulmonary Reserve In COPD | Full Text | References | PDF (984.3 KB) | EPUB
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Original Research

Article
Body Composition of Filipino Chronic Obstructive Pulmonary Disease (COPD) Patients in Relation to Their Lung Function, Exercise Capacity and Quality of Life
Jamie R Chua, Albert B Albay Jr & Michael L Tee
Pages: 2759-2765
Published online: 02 Dec 2019
AbstractforBody Composition of Filipino Chronic Obstructive Pulmonary Disease (COPD) Patients in Relation to Their Lung Function, Exercise Capacity and Quality of Life | Full Text | References | PDF (347.2 KB) | EPUB
  • 392 Views
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Article
Critical Inhaler Handling Error Is an Independent Risk Factor for Frequent Exacerbations of Chronic Obstructive Pulmonary Disease: Interim Results of a Single Center Prospective Study
June Hong Ahn, Jin Hong Chung, Kyeong-Cheol Shin, Eun Young Choi, Hyun Jung Jin, Mi Suk Lee, Mi Jeong Nam & Kwan Ho Lee
Pages: 2767-2775
Published online: 24 Oct 2022
AbstractforCritical Inhaler Handling Error Is an Independent Risk Factor for Frequent Exacerbations of Chronic Obstructive Pulmonary Disease: Interim Results of a Single Center Prospective Study | Full Text | References | PDF (441.8 KB) | EPUB
  • 158 Views
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Article
Repetitive Saliva Swallowing Test Predicts COPD Exacerbation
Yuki Yoshimatsu, Kazunori Tobino, Takuto Sueyasu, Saori Nishizawa, Yuki Ko, Mina Yasuda, Hiromi Ide, Kosuke Tsuruno & Hiroyuki Miyajima
Pages: 2777-2785
Published online: 04 Dec 2019
AbstractforRepetitive Saliva Swallowing Test Predicts COPD Exacerbation | Full Text | References | PDF (3.9 MB) | EPUB
  • 203 Views
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Article
Clinical Effects Of Acupuncture On The Pathophysiological Mechanism Of Chronic Obstructive Pulmonary Disease During Exercise
Tomonori Maekura, Keisuke Miki, Mari Miki, Seigo Kitada & Ryoji Maekura
Pages: 2787-2798
Published online: 05 Dec 2019
AbstractforClinical Effects Of Acupuncture On The Pathophysiological Mechanism Of Chronic Obstructive Pulmonary Disease During Exercise | Full Text | References | PDF (1.6 MB) | EPUB
  • 173 Views
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Article
“Breathing New Life Into Chronic Obstructive Pulmonary Disease (COPD)” – Results From An Online Survey Of UK Patients
Steve Titmarsh, Michele Poliziani & Richard E Russell
Pages: 2799-2807
Published online: 24 Oct 2022
Abstractfor“Breathing New Life Into Chronic Obstructive Pulmonary Disease (COPD)” – Results From An Online Survey Of UK Patients | Full Text | References | PDF (2.7 MB) | EPUB
  • 180 Views
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Article
Not All COPD Patients Benefit from Prophylactic Noninvasive Ventilation After Scheduled Extubation: An Exploratory Study
Yan Gong, Xiaoli Han, Jun Duan & Shicong Huang
Pages: 2809-2814
Published online: 05 Dec 2019
AbstractforNot All COPD Patients Benefit from Prophylactic Noninvasive Ventilation After Scheduled Extubation: An Exploratory Study | Full Text | References | PDF (1.1 MB) | EPUB
  • 83 Views
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Article
Physical Activity in Patients with Chronic Obstructive Pulmonary Disease on Long-Term Oxygen Therapy: A Cross-Sectional Study
Mara Paneroni, Nicolino Ambrosino, Carla Simonelli, Laura Bertacchini, Massimo Venturelli & Michele Vitacca
Pages: 2815-2823
Published online: 05 Dec 2019
AbstractforPhysical Activity in Patients with Chronic Obstructive Pulmonary Disease on Long-Term Oxygen Therapy: A Cross-Sectional Study | Full Text | References | PDF (855.1 KB) | EPUB
  • 210 Views
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Study Protocol

Brief Report
Predictive Value of Combining Inflammatory Biomarkers and Rapid Decline of FEV1 for COPD in Chinese Population: A Prospective Cohort Study
Yunxia Wang, Jiping Liao, Yijue Zhong, Cheng Zhang, Xueying Li & Guangfa Wang
Pages: 2825-2833
Published online: 05 Dec 2019
AbstractforPredictive Value of Combining Inflammatory Biomarkers and Rapid Decline of FEV1 for COPD in Chinese Population: A Prospective Cohort Study | Full Text | References | PDF (307.3 KB) | EPUB
  • 103 Views
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Review

Review Article
An Evaluation Of Single And Dual Long-Acting Bronchodilator Therapy As Effective Interventions In Maintenance Therapy-Naïve Patients With COPD
Dave Singh, Anthony D D’Urzo, James F Donohue, Edward M Kerwin, Eduard Molins, Ferran Chuecos, Anna Ribera & Diana Jarreta
Pages: 2835-2848
Published online: 06 Dec 2019
AbstractforAn Evaluation Of Single And Dual Long-Acting Bronchodilator Therapy As Effective Interventions In Maintenance Therapy-Naïve Patients With COPD | Full Text | References | PDF (4.5 MB) | EPUB
  • 208 Views
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Original Research

Article
The IMPACT Study – Single Inhaler Triple Therapy (FF/UMEC/VI) Versus FF/VI And UMEC/VI In Patients With COPD: Efficacy And Safety In A Japanese Population
Motokazu Kato, Keisuke Tomii, Kenichi Hashimoto, Yasuko Nezu, Takeo Ishii, C Elaine Jones, Sally Kilbride, Annette S Gross, Christine S Clifton & David A Lipson
Pages: 2849-2861
Published online: 06 Dec 2019
AbstractforThe IMPACT Study – Single Inhaler Triple Therapy (FF/UMEC/VI) Versus FF/VI And UMEC/VI In Patients With COPD: Efficacy And Safety In A Japanese Population | Full Text | References | PDF (582.5 KB) | EPUB
  • 159 Views
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Article
Influence of Emphysema and Air Trapping Heterogeneity on Pulmonary Function in Patients with COPD
Kun Li, Yanli Gao, Zhenyu Pan, Xiuqin Jia, Yuchang Yan, Xiaohong Min, Kewu Huang & Tao Jiang
Pages: 2863-2872
Published online: 24 Oct 2022
AbstractforInfluence of Emphysema and Air Trapping Heterogeneity on Pulmonary Function in Patients with COPD | Full Text | References | PDF (4.2 MB) | EPUB
  • 122 Views
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Article
Metabolic Syndrome in Early Chronic Obstructive Pulmonary Disease: Gender Differences and Impact on Exacerbation and Medical Costs
Hye Sook Choi, Chin Kook Rhee, Yong Bum Park, Kwang Ha Yoo & Seong Yong Lim
Pages: 2873-2883
Published online: 10 Dec 2019
AbstractforMetabolic Syndrome in Early Chronic Obstructive Pulmonary Disease: Gender Differences and Impact on Exacerbation and Medical Costs | Full Text | References | PDF (826.8 KB) | EPUB
  • 148 Views
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Article
Serum Alpha-1 Antitrypsin Levels and the Clinical Course of Chronic Obstructive Pulmonary Disease
Nozomu Takei, Masaru Suzuki, Hironi Makita, Satoshi Konno, Kaoruko Shimizu, Hiroki Kimura, Hirokazu Kimura & Masaharu Nishimura
Pages: 2885-2893
Published online: 10 Dec 2019
AbstractforSerum Alpha-1 Antitrypsin Levels and the Clinical Course of Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (993.7 KB) | EPUB
  • 122 Views
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Article
Convergent Validity and Minimal Clinically Important Difference of the Maugeri Foundation Respiratory Failure Questionnaire (MRF-28) and the Chronic Obstructive Pulmonary Disease-Specific Health-Related Quality of Life questionnaire (VQ11)
Jérémy B Coquart, Natacha Heutte, Gaelle Terce & Jean-Marie Grosbois
Pages: 2895-2903
Published online: 13 Dec 2019
AbstractforConvergent Validity and Minimal Clinically Important Difference of the Maugeri Foundation Respiratory Failure Questionnaire (MRF-28) and the Chronic Obstructive Pulmonary Disease-Specific Health-Related Quality of Life questionnaire (VQ11) | Full Text | References | PDF (935 KB) | EPUB
  • 96 Views
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Article
Impact of Therapy Persistence on Exacerbations and Resource Use in Patients Who Initiated COPD Therapy
Faustine Dalon, Gilles Devouassoux, Manon Belhassen, Gaëlle Nachbaur, Camille Correia Da Silva, Lynda Sail, Flore Jacoud, Christos Chouaid & Eric Van Ganse
Pages: 2905-2915
Published online: 16 Dec 2019
AbstractforImpact of Therapy Persistence on Exacerbations and Resource Use in Patients Who Initiated COPD Therapy | Full Text | References | PDF (1.7 MB) | EPUB
  • 73 Views
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Article
Assessment of COPD-Related Knowledge Among Internal Medicine Nurses: A Cross-Sectional Study
Yiming Ma, Yating Peng, Ping Chen, Na Nie & Yan Chen
Pages: 2917-2925
Published online: 17 Dec 2019
AbstractforAssessment of COPD-Related Knowledge Among Internal Medicine Nurses: A Cross-Sectional Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 575 Views
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Clinical Trial Report

Case Report
Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis
Igor Z Barjaktarevic, Russell G Buhr, Xiaoyan Wang, Scott Hu, David Couper, Wayne Anderson, Richard E Kanner, Robert Paine III, Surya P Bhatt, Nirav R Bhakta, Mehrdad Arjomandi, Robert J Kaner, Cheryl S Pirozzi, Jeffrey L Curtis, Wanda K O’Neal, Prescott G Woodruff, MeiLan K Han, Fernando J Martinez, Nadia Hansel, James Michael Wells, Victor E Ortega, Eric A Hoffman, Claire M Doerschuk, Victor Kim, Mark T Dransfield, M Bradley Drummond, Russell Bowler, Gerard Criner, Stephanie A Christenson, Bonnie Ronish, Stephen P Peters, Jerry A Krishnan, Donald P Tashkin, Christopher B Cooper & On behalf of the NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS)
Pages: 2927-2938
Published online: 20 Dec 2019
AbstractforClinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis | Full Text | References | PDF (5.1 MB) | EPUB
  • 132 Views
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Original Research

Article
Comparative Effectiveness Of Fluoroquinolone Antibiotic Use In Uncomplicated Acute Exacerbations Of COPD: A Multi-Cohort Study
Pierre Ernst, Matthew Dahl, Dan Chateau, Nick Daneman, Jacqueline Quail, Ingrid S Sketris, Anat Fisher, Jianguo Zhang, Shawn Bugden & On behalf of the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators
Pages: 2939-2946
Published online: 18 Dec 2019
AbstractforComparative Effectiveness Of Fluoroquinolone Antibiotic Use In Uncomplicated Acute Exacerbations Of COPD: A Multi-Cohort Study | Full Text | References | PDF (2.2 MB) | EPUB
  • 113 Views
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Review

Review Article
Revefenacin: A Once-Daily, Long-Acting Bronchodilator For Nebulized Treatment Of COPD
James F Donohue, Donald A Mahler & Sanjay Sethi
Pages: 2947-2958
Published online: 19 Dec 2019
AbstractforRevefenacin: A Once-Daily, Long-Acting Bronchodilator For Nebulized Treatment Of COPD | Full Text | References | PDF (2.2 MB) | EPUB
  • 149 Views
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Original Research

Article
A Cross-Sectional Study in Patients with Severe COPD to Assess the Perception of Symptom Variability (COPVAR) in the Middle East and Africa
Nurdan Kokturk, Wael Abuharbid, Amr S Albanna, Hakan Gunen, Alev Gurgun, Mousa Khadadah, Elmas Malvolti, Medhat Soliman, Richard van Zyl-Smit, Noureddine Zidouni & Ashraf Alzaabi
Pages: 2959-2970
Published online: 20 Dec 2019
AbstractforA Cross-Sectional Study in Patients with Severe COPD to Assess the Perception of Symptom Variability (COPVAR) in the Middle East and Africa | Full Text | References | PDF (733 KB) | EPUB
  • 76 Views
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Article
Novel Respiratory Impedance-Based Phenotypes Reflect Different Pathophysiologies in Chronic Obstructive Pulmonary Disease Patients
Yumiko Matsuo, Emiko Ogawa, Ruriko Seto-Yukimura, Yasushi Ryujin, Daisuke Kinose, Masafumi Yamaguchi, Makoto Osawa, Taishi Nagao, Hajime Kurosawa & Yasutaka Nakano
Pages: 2971-2977
Published online: 20 Dec 2019
AbstractforNovel Respiratory Impedance-Based Phenotypes Reflect Different Pathophysiologies in Chronic Obstructive Pulmonary Disease Patients | Full Text | References | PDF (465.5 KB) | EPUB
  • 86 Views
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Article
Efficacy and Safety of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD: A Subgroup Analysis of the KRONOS Study
Masakazu Ichinose, Yasushi Fukushima, Yoshikazu Inoue, Osamu Hataji, Gary T Ferguson, Klaus F Rabe, Nobuya Hayashi, Hiroshi Okada, Mami Takikawa, Eric Bourne, Shaila Ballal, Kiernan DeAngelis, Magnus Aurivillius, Paul Dorinsky & Colin Reisner
Pages: 2979-2991
Published online: 23 Dec 2019
AbstractforEfficacy and Safety of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD: A Subgroup Analysis of the KRONOS Study | Full Text | References | PDF (2.7 MB) | EPUB
  • 138 Views
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Article
Long-Term Safety and Efficacy of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD
Masakazu Ichinose, Yasushi Fukushima, Yoshikazu Inoue, Osamu Hataji, Gary T Ferguson, Klaus F Rabe, Nobuya Hayashi, Hiroshi Okada, Mami Takikawa, Eric Bourne, Shaila Ballal, Kiernan DeAngelis, Magnus Aurivillius, Colin Reisner & Paul Dorinsky
Pages: 2993-3002
Published online: 23 Dec 2019
AbstractforLong-Term Safety and Efficacy of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD | Full Text | References | PDF (2 MB) | EPUB
  • 123 Views
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Clinical Trial Report

Case Report
Peripheral Blood Eosinophil as a Biomarker in Outcomes of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Hong-Xia Wu, Kai-Quan Zhuo & De-Yun Cheng
Pages: 3003-3015
Published online: 24 Dec 2019
AbstractforPeripheral Blood Eosinophil as a Biomarker in Outcomes of Acute Exacerbation of Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (326.5 KB) | EPUB
  • 198 Views
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Original Research

Article
Baseline Exercise Tolerance and Perceived Dyspnea to Identify the Ideal Candidate to Pulmonary Rehabilitation: A Risk Chart in COPD Patients
Stefania Costi, Ernesto Crisafulli, Ludovico Trianni, Bianca Beghè, Silvia Faverzani, Giuseppe Scopelliti, Alfredo Chetta & Enrico Clini
Pages: 3017-3023
Published online: 27 Dec 2019
AbstractforBaseline Exercise Tolerance and Perceived Dyspnea to Identify the Ideal Candidate to Pulmonary Rehabilitation: A Risk Chart in COPD Patients | Full Text | References | PDF (2.9 MB) | EPUB
  • 105 Views
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Article
Lifetime Occupational History, Respiratory Symptoms and Chronic Obstructive Pulmonary Disease: Results from a Population-Based Study
Denis Vinnikov, Aizhan Raushanova, Aizhan Kyzayeva, Zhanna Romanova, Zhangir Tulekov, Dinara Kenessary & Ardak Auyezova
Pages: 3025-3034
Published online: 30 Dec 2019
AbstractforLifetime Occupational History, Respiratory Symptoms and Chronic Obstructive Pulmonary Disease: Results from a Population-Based Study | Full Text | References | PDF (695.6 KB) | EPUB
  • 187 Views
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Article
Mixed Phenotype of Emphysema and Airway Wall Thickening Is Associated with Frequent Exacerbation in Chronic Obstructive Pulmonary Disease Patients
Jeong Uk Lim, Eun Kyung Kim, Seong Yong Lim, Jin Hwa Lee, Jae Seung Lee, Sang-Do Lee, Yeon-Mok Oh, Chin Kook Rhee & On behalf of the KOLD Study Group
Pages: 3035-3042
Published online: 30 Dec 2019
AbstractforMixed Phenotype of Emphysema and Airway Wall Thickening Is Associated with Frequent Exacerbation in Chronic Obstructive Pulmonary Disease Patients | Full Text | References | PDF (868.3 KB) | EPUB
  • 88 Views
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Article
CAT Score and SGRQ Definitions of Chronic Bronchitis as an Alternative to the Classical Definition
Joon Young Choi, Hyoung Kyu Yoon, Kyeong-Cheol Shin, So-Young Park, Chang Youl Lee, Seung Won Ra, Ki Suck Jung, Kwang Ha Yoo, Chang-Hoon Lee & Chin Kook Rhee
Pages: 3043-3052
Published online: 30 Dec 2019
AbstractforCAT Score and SGRQ Definitions of Chronic Bronchitis as an Alternative to the Classical Definition | Full Text | References | PDF (1 MB) | EPUB
  • 164 Views
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Article
Low Liver Density Is Linked to Cardiovascular Comorbidity in COPD: An ECLIPSE Cohort Analysis
Damien Viglino, Mickaël Martin, Natalie Almeras, Jean-Pierre Després, Harvey O Coxson, Jean-Louis Pépin, Isabelle Vivodtzev, François Maltais & On behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators
Pages: 3053-3061
Published online: 03 Jan 2020
AbstractforLow Liver Density Is Linked to Cardiovascular Comorbidity in COPD: An ECLIPSE Cohort Analysis | Full Text | References | PDF (2.1 MB) | EPUB
  • 109 Views
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Short Report

Brief Report
Inhaled Corticosteroids Prescribed for COPD Patients with Mild or Moderate Airflow Limitation: Who Warrants a Trial of Withdrawal?
Timothy H Harries, Gill Gilworth, Christopher J Corrigan, Patrick B Murphy, Nicholas Hart, Mike Thomas & Patrick T White
Pages: 3063-3066
Published online: 03 Jan 2020
AbstractforInhaled Corticosteroids Prescribed for COPD Patients with Mild or Moderate Airflow Limitation: Who Warrants a Trial of Withdrawal? | Full Text | References | PDF (399.4 KB) | EPUB
  • 56 Views
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