The effects of deep transcranial magnetic stimulation on Alzheimer’s disease: a case report examining cognitive functioning, memory, and QEEG

ABSTRACT

Numerous treatment options are being studied for Alzheimer’s disease (AD) given the rising prevalence of this condition worldwide. Transcranial Magnetic Stimulation (TMS) is a promising option for regulating specific neurological abnormalities pertaining to this condition. This case presents a patient with AD and co-occurring major depressive disorder that received 36 sessions of Deep TMS to the frontal and temporal lobes. This patient experienced improved general cognitive functioning and memory, remission from depression, and reduced slow-frequency theta activity in frontal and temporal sites. Following 7 months of weekly maintenance, additional improvements occurred. This report suggests that Deep TMS may be effective in mitigating AD symptoms, and maintenance sessions are advisable.

KEYWORDS:

• Deep TMS
• Alzheimer’s Disease
• EEG biomarkers
• major depressive disorder
• temporal lobe

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The data presented in this manuscript is available upon request.

Additional information

Funding

The author(s) reported thereis no funding associated with the work featured in this article.