Psychiatric disorders in perinatally HIV-exposed, uninfected children: a systematic review

References

• Abrams, E. J., Mellins, C. A., Bucek, A., Dolezal, C., Raymond, J., Wiznia, A., Jurgrau, A., Bamji, M., Leu, C. S., & Ng, Y. K. W. (2018). Behavioral health and adult milestones in young adults with perinatal HIV infection or exposure. Pediatrics, 142(3), https://doi.org/10.1542/peds.2018-0938
   PubMed Web of Science ®Google Scholar
• Afran, L., Garcia Knight, M., Nduati, E., Urban, B. C., Heyderman, R. S., & Rowland-Jones, S. L. (2014). HIV-exposed uninfected children: A growing population with a vulnerable immune system? Clinical and Experimental Immunology, 176(1), 11–22. https://doi.org/10.1111/cei.12251
   PubMed Web of Science ®Google Scholar
• Ajaykumar, A., Zhu, M., Kakkar, F., Brophy, J., Bitnun, A., Alimenti, A., Soudeyns, H., Saberi, S., Albert, A. Y. K., Money, D. M., & Côté, H. C. F. (2021). Elevated blood mitochondrial DNA in early life among uninfected children exposed to human immunodeficiency virus and combination antiretroviral therapy in utero. The Journal of Infectious Diseases, 223(4), 621–631. https://doi.org/10.1093/infdis/jiaa410
   PubMed Web of Science ®Google Scholar
• Al-Haddad, B. J. S., Oler, E., Armistead, B., Elsayed, N. A., Weinberger, D. R., Bernier, R., Burd, I., Kapur, R., Jacobsson, B., Wang, C., Mysorekar, I., Rajagopal, L., & Adams Waldorf, K. M. (2019). The fetal origins of mental illness. American Journal of Obstetrics and Gynecology, 221(6), 549–562. https://doi.org/10.1016/j.ajog.2019.06.013
   PubMed Web of Science ®Google Scholar
• American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM-5. American Psychiatric Association
   Google Scholar
• Bauman, L. J., Silver, E. J., Draimin, B. H., & Hudis, J. (2007). Children of mothers with HIV/AIDS: Unmet needs for mental health services. Pediatrics, 120(5), e1141–e1147. https://doi.org/10.1542/peds.2005-2680
   PubMed Web of Science ®Google Scholar
• Betancourt, T., Scorza, P., Kanyanganzi, F., Fawzi, M. C., Sezibera, V., Cyamatare, F., Beardslee, W., Stulac, S., Bizimana, J. I., Stevenson, A., & Kayiteshonga, Y. (2014). HIV and child mental health: A case-control study in Rwanda. Pediatrics, 134(2), e464–e472. https://doi.org/10.1542/peds.2013-2734
   PubMed Web of Science ®Google Scholar
• Brennan, A. T., Bonawitz, R., Gill, C. J., Thea, D. M., Kleinman, M., Long, L., McCallum, C., & Fox, M. P. (2019). A meta-analysis assessing diarrhea and pneumonia in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children. JAIDS Journal of Acquired Immune Deficiency Syndromes, 82(1), 1–8. https://doi.org/10.1097/QAI.0000000000002097
   PubMed Web of Science ®Google Scholar
• Brennan, A. T., Bonawitz, R., Gill, C. J., Thea, D. M., Kleinman, M., Useem, J., Garrison, L., Ceccarelli, R., Udokwu, C., Long, L., & Fox, M. P. (2016). A meta-analysis assessing all-cause mortality in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children. Aids (london, England), 30(15), 2351–2360. https://doi.org/10.1097/QAD.0000000000001211
   PubMed Web of Science ®Google Scholar
• Brennand, K., Savas, J. N., Kim, Y., Tran, N., Simone, A., Hashimoto-Torii, K., Beaumont, K. G., Kim, H. J., Topol, A., Ladran, I., Abdelrahim, M., Matikainen-Ankney, B., Chao, S. H., Mrksich, M., Rakic, P., Fang, G., Zhang, B., Yates, J. R., & Gage, F. H. (2015). Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Molecular Psychiatry, 20(3), 361–368. https://doi.org/10.1038/mp.2014.22
   PubMed Web of Science ®Google Scholar
• Bucek, A., Mellins, C. A., Leu, C. S., Dolezal, C., Korich, R., Wiznia, A., & Abrams, E. J. (2020). Psychiatric disorders and young adult milestones in HIV-exposed, uninfected youth. AIDS Care, 32(4), 420–428. https://doi.org/10.1080/09540121.2019.1668535
   PubMed Web of Science ®Google Scholar
• Chernoff, M., Nachman, S., Williams, P., Brouwers, P., Heston, J., Hodge, J., Di Poalo, V., Deygoo, N. S., & Gadow, K. D. (2009). Mental health treatment patterns in perinatally HIV-infected youth and controls. Pediatrics, 124(2), 627–636. https://doi.org/10.1542/peds.2008-2441
   PubMed Web of Science ®Google Scholar
• Chugani, D. C., Sundram, B. S., Behen, M., Lee, M. L., & Moore, G. J. (1999). Evidence of altered energy metabolism in autistic children. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 23(4), 635–641. https://doi.org/10.1016/S0278-5846(99)00022-6
   PubMed Web of Science ®Google Scholar
• Côté, H. C., Raboud, J., Bitnun, A., Alimenti, A., Money, D. M., Maan, E., Costei, A., Gadawski, I., Diong, C., Read, S., Shen, S., Harrigan, P. R., Burdge, D. R., King, S. M., & Forbes, J. C. (2008). Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants. The Journal of Infectious Diseases, 198(6), 851–859. https://doi.org/10.1086/591253
   PubMed Web of Science ®Google Scholar
• Desmonde, S., Goetghebuer, T., Thorne, C., & Leroy, V. (2016). Health and survival of HIV perinatally exposed but uninfected children born to HIV-infected mothers. Current Opinion in HIV and AIDS, 11(5), 465–476. https://doi.org/10.1097/COH.0000000000000300
   PubMed Web of Science ®Google Scholar
• Esposito, S., Musetti, L., Musetti, M. C., Tornaghi, R., Corbella, S., Massironi, E., Marchisio, P., Guareschi, A., & Principi, N. (1999). Behavioral and psychological disorders in uninfected children aged 6 to 11 years born to human immunodeficiency virus-seropositive mothers. Journal of Developmental & Behavioral Pediatrics, 20(6), 411–417. https://doi.org/10.1097/00004703-199912000-00002
   PubMed Web of Science ®Google Scholar
• Evans, C., Jones, C. E., & Prendergast, A. J. (2016). HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination. The Lancet Infectious Diseases, 16(6), e92–e107. https://doi.org/10.1016/S1473-3099(16)00055-4
   PubMedGoogle Scholar
• Farrah, K., Young, K., Tunis, M. C., & Zhao, L. (2019). Risk of bias tools in systematic reviews of health interventions: An analysis of PROSPERO-registered protocols. Systematic Reviews, 8(1), 280. https://doi.org/10.1186/s13643-019-1172-8
   PubMed Web of Science ®Google Scholar
• Gadow, K. D., Angelidou, K., Chernoff, M., Williams, P. L., Heston, J., Hodge, J., & Nachman, S. (2012). Longitudinal study of emerging mental health concerns in youth perinatally infected with HIV and peer comparisons. Journal of Developmental & Behavioral Pediatrics, 33(6), 456–468. https://doi.org/10.1097/DBP.0b013e31825b8482
   PubMed Web of Science ®Google Scholar
• Haslam, N. (2003). Categorical versus dimensional models of mental disorder: The taxometric evidence. Australian & New Zealand Journal of Psychiatry, 37(6), 696–704. https://doi.org/10.1080/j.1440-1614.2003.01258.x
   PubMed Web of Science ®Google Scholar
• Hayatbakhsh, M. R., O'Callaghan, M. J., Bor, W., Williams, G. M., & Najman, J. M. (2012). Association of breastfeeding and adolescents’ psychopathology: a large prospective study. Breastfeeding Medicine, 7(6), 480–486. https://doi.org/10.1089/bfm.2011.0136
   PubMed Web of Science ®Google Scholar
• Heidari, S., Mofenson, L., Cotton, M. F., Marlink, R., Cahn, P., & Katabira, E. (2011). Antiretroviral drugs for preventing mother-to-child transmission of HIV: A review of potential effects on HIV-exposed but uninfected children. JAIDS Journal of Acquired Immune Deficiency Syndromes, 57(4), 290–296. https://doi.org/10.1097/QAI.0b013e318221c56a
   PubMed Web of Science ®Google Scholar
• Higgins, J. (2020). Cochrane handbook for systematic reviews of interventions. Cochrane Training. Retrieved 01/11/2021 from https://handbook-5-1.cochrane.org/chapter_7/7_7_3_2_obtaining_standard_deviations_from_standard_errors_and.htm.
   Google Scholar
• James, S. J., Rose, S., Melnyk, S., Jernigan, S., Blossom, S., Pavliv, O., & Gaylor, D. W. (2009). Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. The FASEB Journal, 23(8), 2374–2383. https://doi.org/10.1096/fj.08-128926
   PubMed Web of Science ®Google Scholar
• Kessler, R. C., Amminger, G. P., Aguilar-Gaxiola, S., Alonso, J., Lee, S., & Ustün, T. B. (2007). Age of onset of mental disorders: A review of recent literature. Current Opinion in Psychiatry, 20(4), 359–364. https://doi.org/10.1097/YCO.0b013e32816ebc8c
   PubMed Web of Science ®Google Scholar
• Lewczyk, C. M., Garland, A. F., Hurlburt, M. S., Gearity, J., & Hough, R. L. (2003). Comparing DISC-IV and clinician diagnoses among youths receiving public mental health services. Journal of the American Academy of Child & Adolescent Psychiatry, 42(3), 349–356. https://doi.org/10.1097/00004583-200303000-00016
   PubMed Web of Science ®Google Scholar
• Malee, K. M., Tassiopoulos, K., Huo, Y., Siberry, G., Williams, P. L., Hazra, R., Smith, R. A., Allison, S. M., Garvie, P. A., Kammerer, B., Kapetanovic, S., Nichols, S., Van Dyke, R., Seage, G. R., Mellins, C. A., & Pediatric, H. I. V. A. C. S. T. (2011). Mental health functioning among children and adolescents with perinatal HIV infection and perinatal HIV exposure. AIDS Care, 23(12), 1533–1544. https://doi.org/10.1080/09540121.2011.575120
   PubMed Web of Science ®Google Scholar
• Mellins, C. A., Brackis-Cott, E., Leu, C. S., Elkington, K. S., Dolezal, C., Wiznia, A., McKay, M., Bamji, M., & Abrams, E. J. (2009). Rates and types of psychiatric disorders in perinatally human immunodeficiency virus-infected youth and seroreverters. Journal of Child Psychology and Psychiatry, 50(9), 1131–1138. https://doi.org/10.1111/j.1469-7610.2009.02069.x
   PubMed Web of Science ®Google Scholar
• Mellins, C. A., Elkington, K. S., Leu, C. S., Santamaria, E. K., Dolezal, C., Wiznia, A., Bamji, M., McKay, M. M., & Abrams, E. J. (2012). Prevalence and change in psychiatric disorders among perinatally HIV-infected and HIV-exposed youth. AIDS Care, 24(8), 953–962. https://doi.org/10.1080/09540121.2012.668174
   PubMed Web of Science ®Google Scholar
• Moseholm, E., Helleberg, M., Sandholdt, H., Katzenstein, T. L., Storgaard, M., Pedersen, G., Johansen, I. S., & Weis, N. (2020). Children exposed or unexposed to human immunodeficiency virus: Weight, height, and body mass index during the first 5 years of life-a danish nationwide cohort. Clinical Infectious Diseases, 70(10), 2168–2177. https://doi.org/10.1093/cid/ciz605
   PubMed Web of Science ®Google Scholar
• Nguyen, N., Choi, C. J., Robbins, R., Korich, R., Raymond, J., Dolezal, C., Leu, C. S., Wiznia, A., Abrams, E. J., & Mellins, C. A. (2020). Psychiatric trajectories across adolescence in perinatally HIV-exposed youth: The role of HIV infection and associations with viral load. Aids (london, England), https://doi.org/10.1097/qad.0000000000002529
   Web of Science ®Google Scholar
• Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71
   PubMed Web of Science ®Google Scholar
• Piske, M., Budd, M. A., Qiu, A. Q., Maan, E. J., Sauvé, L. J., Forbes, J. C., Alimenti, A., Janssen, P., & Côté, H. C. F. (2018). Neurodevelopmental outcomes and in-utero antiretroviral exposure in HIV-exposed uninfected children. Aids (london, England), 32(17), 2583–2592. https://doi.org/10.1097/QAD.0000000000001985
   PubMed Web of Science ®Google Scholar
• Polanczyk, G. V., Salum, G. A., Sugaya, L. S., Caye, A., & Rohde, L. A. (2015). Annual research review: A meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. Journal of Child Psychology and Psychiatry, 56(3), 345–365. https://doi.org/10.1111/jcpp.12381
   PubMed Web of Science ®Google Scholar
• Prabakaran, S., Swatton, J. E., Ryan, M. M., Huffaker, S. J., Huang, J. T., Griffin, J. L., Wayland, M., Freeman, T., Dudbridge, F., Lilley, K. S., Karp, N. A., Hester, S., Tkachev, D., Mimmack, M. L., Yolken, R. H., Webster, M. J., Torrey, E. F., & Bahn, S. (2004). Mitochondrial dysfunction in schizophrenia: Evidence for compromised brain metabolism and oxidative stress. Molecular Psychiatry, 9(7), 684–697. https://doi.org/10.1038/sj.mp.4001511
   PubMed Web of Science ®Google Scholar
• Ramokolo, V., Goga, A. E., Slogrove, A. L., & Powis, K. M. (2019). Unmasking the vulnerabilities of uninfected children exposed to HIV. BMJ, 366, l4479. https://doi.org/10.1136/bmj.l4479
   PubMedGoogle Scholar
• Rochat, T. J., Houle, B., Stein, A., Pearson, R. M., & Bland, R. M. (2018). Prevalence and risk factors for child mental disorders in a population-based cohort of HIV-exposed and unexposed African children aged 7–11 years. European Child & Adolescent Psychiatry, 27(12), 1607–1620. https://doi.org/10.1007/s00787-018-1146-8
   PubMed Web of Science ®Google Scholar
• Scaini, G., Rezin, G. T., Carvalho, A. F., Streck, E. L., Berk, M., & Quevedo, J. (2016). Mitochondrial dysfunction in bipolar disorder: Evidence, pathophysiology and translational implications. Neuroscience & Biobehavioral Reviews, 68, 694–713. https://doi.org/10.1016/j.neubiorev.2016.06.040
   PubMed Web of Science ®Google Scholar
• Slogrove, A. L., Powis, K. M., Johnson, L. F., Stover, J., & Mahy, M. (2020). Estimates of the global population of children who are HIV-exposed and uninfected, 2000-18: A modelling study. The Lancet Global Health, 8(1), e67–e75. https://doi.org/10.1016/S2214-109X(19)30448-6
   PubMed Web of Science ®Google Scholar
• Smith, R., Huo, Y., Tassiopoulos, K., Rutstein, R., Kapetanovic, S., Mellins, C., Kacanek, D., & Malee, K. (2019). Mental health diagnoses, symptoms, and service utilization in US youth with perinatal HIV infection or HIV exposure. AIDS Patient Care and STDS, 33(1), 1–13. https://doi.org/10.1089/apc.2018.0096
   PubMed Web of Science ®Google Scholar
• Son, G., & Han, J. (2018). Roles of mitochondria in neuronal development. BMB Reports, 51(11), 549–556. https://doi.org/10.5483/BMBRep.2018.51.11.226
   PubMed Web of Science ®Google Scholar
• Stein, D. J., & Reed, G. M. (2019). Global mental health and psychiatric nosology: DSM-5, ICD-11, and RDoC. Brazilian Journal of Psychiatry, 41(1), 3–4. https://doi.org/10.1590/1516-4446-2018-4101
   Web of Science ®Google Scholar
• Thorne, C., & Newell, M. L. (2007). Safety of agents used to prevent mother-to-child transmission of HIV. Drug Safety, 30(3), 203–213. https://doi.org/10.2165/00002018-200730030-00004
   PubMed Web of Science ®Google Scholar
• UNAIDS. (2020). AIDSinfo. Retrieved 1/20-21 from https://aidsinfo.unaids.org.
   Google Scholar
• Wells, G. A., Shea, B., O’Connell, D. A., Peterson, J., Welch, V., Losos, M., & Tugwell, P. (2000). The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses.
   Google Scholar
• World Health Organization. (2004). ICD-10: International statistical classification of diseases and related health problems / World Health Organization. World Health Organization.
   Google Scholar
• World Health Organization. (2021). HIV/AIDS. https://www.who.int/news-room/fact-sheets/detail/hiv-aids.
   Google Scholar