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Research Article

Analysis of mitochondrial DNA copy number variation in Brazilian farmers occupationally exposed to pesticides

ORCID Icon, ORCID Icon & ORCID Icon
Received 02 May 2023, Accepted 02 Nov 2023, Published online: 15 Nov 2023

References

  • Agrawal S, Singh A, Tripathi P, Mishra M, Singh PK, Singh MP. 2015. Cypermethrin-induced nigrostriatal dopaminergic neurodegeneration alters the mitochondrial function: A proteomics study. Mol Neurobiol. 51(2):448–465. doi: 10.1007/s12035-014-8696-7.
  • Alavanja MCR, Sandler DP, Mcmaster SB, Zahm SH, Mcdonnell CJ, Lynch CF, Penn M, Rothman N, Dosemeci M, Bond AE, et al. 1996. The agricultural Health study. Environ Health-Glob. 104(4):362–369. doi: 10.1289/ehp.96104362.
  • Andrews SJ. 2021. Alzheimer’s disease is causally associated with mitochondrial dysfunction. Alzheimer’s & Dementia. 17(S3):17. doi: 10.1002/alz.057480.
  • Arbo MD, Garcia SC, Sarpa M, Silva Junior FMR D, Nascimento SN, Garcia ALH, Da Silva J. 2022. Brazilian workers occupationally exposed to different toxic agents: a systematic review on DNA damage. Mutat Res Genet Toxicol Environ Mutagen. 879-880:503519–503880. doi: 10.1016/j.mrgentox.2022.503519.
  • Bailey DC, Todt CE, Burchfield SL, Pressley AS, Denney RD, Snapp IB, Negga R, Traynor WL, Fitsanakis VA. 2018. Chronic exposure to a glyphosate-containing pesticide leads to mitochondrial dysfunction and increased reactive oxygen species production in Caenorhabditiselegans. Environ Toxicol Pharmacol. 57:46–52. doi: 10.1016/j.etap.2017.11.005.
  • Borghini A, Vecoli C, Mercuri A, Turchi S, Piccaluga E, Guagliumi G, Picano E, Andreassi MG. 2018. P6200Increased mitochondrial 4977-bp deletion and copy number in cath lab personnel with long-term occupational exposure to ionizing radiation. Eur Heart J. 39(suppl_1). doi: 10.1093/eurheartj/ehy566.p6200.
  • Caliri AW, Tommasi S, Besaratinia A. 2021. Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer. Mutat Res Rev Mutat Res. 787:108365. doi: 10.1016/j.mrrev.2021.108365.
  • Carugno M, Pesatori AC, Dioni L, Hoxha M, Bollati V, Albetti B, Byun HM, Bonzini M, Fustinoni S, Cocco P, et al. 2012. Increased mitochondrial DNA copy number in occupations associated with low-dose benzene exposure. Environ Health Perspect. 120(2):210–215. doi:10.1289/ehp.1103979.
  • Castellani CA, Longchamps RJ, Sumpter JA, Newcomb CE, Lane JA, Grove ML, Bressler J, Brody JA, Floyd JS, Bartz TM, et al. 2020. Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs. Genome Med. 12(1). doi:10.1186/s13073-020-00778-7.
  • Dolcini J, Wu H, Nwanaji-Enwerem JC, Kiomourtozlogu MA, Cayir A, Sanchez-Guerra M, Vokonas P, Schwarz J, Baccarelli AA. 2020. Mitochondria and aging in older individuals: an analysis of DNA methylation age metrics, leukocyte telomere length, and mitochondrial DNA copy number in the VA normative aging study. Aging. 12(3):2070–2083. doi: 10.18632/aging.102722.
  • dos Santos IC, da Silva JT, Rohr P, Lengert AVH, de Lima MA, Kahl VFS, da Silva J, Reis RM, Silveira HCS. 2022. Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides. Mutat Res Genet Toxicol Environ Mutagen. 878:503479. doi: 10.1016/j.mrgentox.2022.503479.
  • Food and Agriculture Organization of the United Nations 2021. World Food and Agriculture – Statistical yearbook 2021:FAO. [place unknown] 10.4060/cb4477en
  • Gerunova LK, Bardina EG, Gerunov TV, Sechkina IV. 2019. Pesticides as endocrine disruptors and neurotoxicants:IOP conf ser: earth Environ Sci. 315, place unknown 10.1088/1755-1315/315/5/0520495052049
  • Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. 2008. Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 42(2):377–381. doi: 10.1016/j.jbi.2008.08.010.
  • Huang PL, Wang MF, Lee HS, Liu YJ, Chen CC, Chen SC, Lai JS, Wong RH. 2011. An OGG1 polymorphism is associated with mitochondrial DNA content in pesticide-exposed fruit growers. Toxicology. 287(1–3):8–14. doi: 10.1016/j.tox.2011.05.001.
  • Javeres MNL, Habib R, Laure NJ, Shah STA, Valis M, Kuca K, Nurulain SM. 2021. Chronic exposure to organophosphates pesticides and risk of metabolic disorder in cohort from Pakistan and Cameroon. Int J Environ Res Public Health. 18(5):2310. doi: 10.3390/ijerph18052310.
  • Ji B, Xiao LY, Ren JC, Zhang GH, Wang Y, Dong T, Li J, Zhang F, Xia ZL. 2021. Gene-environment interactions between environmental response genes polymorphisms and mitochondrial DNA copy numbers among benzene workers. J Occup Environ Med. 63(7):e408–e415. doi: 10.1097/JOM.0000000000002225.
  • Kaur R, Kaur S, Lata M. 2011. Evaluation of DNA damage in agricultural workers exposed to pesticides using single cell gel electrophoresis (comet) assay. Indian J Hum Genet. 17(3):179. doi: 10.4103/0971-6866.92100.
  • Kim HY, Kim HR, Kang MG, Trang NTD, Baek HJ, Moon JD, Shin JH, Suh SP, Ryang DW, Kook H, et al. 2014. Profiling of biomarkers for the exposure of polycyclic aromatic hydrocarbons: lamin-A/C isoform 3, poly[ADP-ribose] polymerase 1, and mitochondria copy number are identified as universal biomarkers. Biomed Res Int. 2014:1–12. doi: 10.1155/2014/605135.
  • Kour P, Tripathi NK 2014. Evaluation of acute toxicity of copper sulphate in different tissues of euphlyctis cyanophlyctis. [Place Unknown]. http://www.aessweb.com/journals/5003
  • Ledda C, Cannizzaro E, Cinà D, Filetti V, Vitale E, Paravizzini G, Di Naso C, Iavicoli I, Rapisarda V. 2021. Oxidative stress and DNA damage in agricultural workers after exposure to pesticides. J Occup Med Toxicol. 16(1). doi: 10.1186/s12995-020-00290-z.
  • Lei L, Guo J, Shi X, Zhang G, Kang H, Sun C, Huang J, Wang T. 2017. Mitochondrial DNA copy number in peripheral blood cell and hypertension risk among mining workers: a case–control study in Chinese coal miners. J Hum Hypertens. 31(9):585–590. doi: 10.1038/jhh.2017.30.
  • Li AJ, Martinez-Moral MP, Al-Malki AL, Al-Ghamdi MA, Al-Bazi MM, Kumosani TA, Kannan K. 2019. Mediation analysis for the relationship between urinary phthalate metabolites and type 2 diabetes via oxidative stress in a population in Jeddah, Saudi Arabia. Environ Int. 126:153–161. doi: 10.1016/j.envint.2019.01.082.
  • Lozano-Paniagua D, Parrón T, Alarcón R, Requena M, Gil F, López-Guarnido O, Lacasaña M, Hernández AF. 2018. Biomarkers of oxidative stress in blood of workers exposed to non-cholinesterase inhibiting pesticides. Ecotoxicol Environ Saf. 162:121–128. doi: 10.1016/j.ecoenv.2018.06.074.
  • Luo D, Zhou T, Tao Y, Feng Y, Shen X, Mei S. 2016. Exposure to organochlorine pesticides and non-Hodgkin lymphoma: a meta-analysis of observational studies. Sci Rep. 6(1):6. doi: 10.1038/srep25768.
  • Martin FL, Martinez EZ, Stopper H, Garcia SB, Uyemura SA, Kannen V. 2018. Increased exposure to pesticides and colon cancer: early evidence in Brazil. Chemosphere. 209:623–631. doi: 10.1016/j.chemosphere.2018.06.118.
  • Meng S, Wu S, Liang L, Liang G, Giovannucci E, De Vivo I, Nan H. 2016. Leukocyte mitochondrial DNA copy number, anthropometric indices, and weight change in US women. Oncotarget. 7(37):60676–60686. doi: 10.18632/oncotarget.10325.
  • Meyer J, Harlev A. 2020. Smoking effects on Male fertility:Male infertility: contemporary clinical approaches, andrology, ART and antioxidants. 2nd. place unknown 10.1007/978-3-030-32300-4_40
  • Miao Y, Rong M, Li M, He H, Zhang L, Zhang S, Liu C, Zhu Y, Deng YL, Chen PP, et al. 2021. Serum concentrations of organochlorine pesticides, biomarkers of oxidative stress, and risk of breast cancer. Environ Pollut. 286:117386. doi: 10.1016/j.envpol.2021.117386.
  • Mi J, Tian G, Liu S, Li X, Ni T, Zhang L, Wang B. 2015. The relationship between altered mitochondrial DNA copy number and cancer risk: A meta-analysis. Sci Rep. 5. doi: 10.1038/srep10039.
  • Nezis I, Biskos G, Eleftheriadis K, Kalantzi OI. 2019. Particulate matter and health effects in offices - a review. Build Environ. 156:62–73. doi: 10.1016/j.buildenv.2019.03.042.
  • Olayinka ET, Ore A. 2015. Hepatotoxicity, nephrotoxicity and oxidative stress in rat testis following exposure to haloxyfop-p-methyl ester, an aryloxyphenoxypropionate herbicide. Toxics. 3(4):373–389. doi: 10.3390/toxics3040373.
  • Park S, Lee JY, Park H, Song G, Lim W 2020. Haloxyfop-P-methyl induces developmental defects in zebrafish embryos through oxidative stress and anti-vasculogenesis. Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology. 233. 10.1016/j.cbpc.2020.108761
  • Pello R, Martín MA, Carelli V, Nijtmans LG, Achilli A, Pala M, Torroni A, Gómez-Durán A, Ruiz-Pesini E, Martinuzzi A, et al. 2008. Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease. Hum Mol Genet. 17(24):4001–4011. doi:10.1093/hmg/ddn303.
  • Praveen G, Shalini T, Sivaprasad M, Reddy GB. 2020. Relative telomere length and mitochondrial DNA copy number variation with age: association with plasma folate and vitamin B12. Mitochondrion. 51:79–87. dos. doi: 10.1016/j.mito.2020.01.007.
  • Sule RO, Condon L, Gomes AV. 2022. A common feature of pesticides: oxidative stress - the role of oxidative stress in pesticide-induced toxicity. Oxid Med Cell Longev. 2022. doi: 10.1155/2022/5563759.
  • Tuanwei W, Tu Y, Wang K, Gong S, Zhang G, Zhang Y, Meng Y, Tongshuai W, Li A, Cui J, et al. 2021. Associations of blood lead levels with multiple genotoxic biomarkers among workers in China: a population-based study. Environ Pollut. 273:116181. doi: 10.1016/j.envpol.2020.116181.
  • Vakonaki E, Androutsopoulos VP, Liesivuori J, Tsatsakis AM, Spandidos DA. 2013. Pesticides and oncogenic modulation. Toxicology. 307:42–45. doi: 10.1016/j.tox.2013.01.008.
  • Vyas CM, Ogata S, Reynolds CF, Mischoulon D, Chang G, Cook NR, Manson JAE, Crous-Bou M, De Vivo I, Okereke OI. 2020. Lifestyle and behavioral factors and mitochondrial DNA copy number in a diverse cohort of mid-life and older adults. PloS One. 15(8 August). doi: 10.1371/journal.pone.0237235.
  • Wang Y, Tan J, Wang W, Duan X, Lappe B, Shi L, Yang Y, Shi X. 2022. The association between polymorphisms in cell-cycle genes and mitochondrial DNA copy number in coke oven workers. Front Public Health. 10:10. doi: 10.3389/fpubh.2022.904856.
  • Wu M, Shu Y, Song L, Liu B, Zhang L, Wang L, Liu Y, Bi J, Xiong C, Cao Z, et al. 2019. Prenatal exposure to thallium is associated with decreased mitochondrial DNA copy number in newborns: evidence from a birth cohort study. Environ Int. 129. 10.1016/j.envint.2019.05.053
  • Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, et al. 2008. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst. 100(15):1104–1112. doi:10.1093/jnci/djn213.
  • Zhang W, Liu Y, An Z, Huang D, Qi Y, Zhang Y. 2011. Mediating effect of ROS on mtDNA damage and low ATP content induced by arsenic trioxide in mouse oocytes. Toxicol In Vitro. 25(4):979–984. doi: 10.1016/j.tiv.2011.03.009.
  • Zhang Y, Qu Y, Gao K, Yang Q, Shi B, Hou P, Ji M. 2015. High copy number of mitochondrial DNA (mtDNA) predicts good prognosis in glioma patients. Am J Cancer Res. 5(3): 1207–1216.

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