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Review Article

Bioaccumulation of potentially toxic elements in leafy and tuberous vegetables: a comparison based on meta-analysis studies with a cumulative health risk assessment

, , , , , , & show all
Received 12 Oct 2023, Accepted 25 Jan 2024, Published online: 12 Feb 2024

References

  • Achakzai AKK, Bazai ZA, Kayani SA. 2011. Accumulation of heavy metals by lettuce (Lactuca sativa L.) irrigated with different levels of wastewater of Quetta city. Pak J Bot. 43(6):2953.
  • Adamo P, Iavazzo P, Albanese S, Agrelli D, De Vivo B, Lima A. 2014. Bioavailability and soil-to-plant transfer factors as indicators of potentially toxic element contamination in agricultural soils. Sci Total Environ. 500-501:11–22. doi: 10.1016/j.scitotenv.2014.08.085.
  • Afonne OJ, Ifediba EC. 2020. Heavy metals risks in plant foods–need to step up precautionary measures. Curr Opin Toxicol. 22:1–6. doi: 10.1016/j.cotox.2019.12.006.
  • Agbenin JO, Danko M, Welp G. 2009. Soil and vegetable compositional relationships of eight potentially toxic metals in urban garden fields from northern Nigeria. J Sci Food Agric. 89(1):49–54. doi: 10.1002/jsfa.3409.
  • Agbim AD, Thomas EY. 2020. Geo-contamination of soils by Heavy Metals and their bio-accumulation in plants as influenced by soil pH, organic matter, and cation exchange capacity. International Annual Meetings. San Antonio, USA: SCISOC; p. 36–42.
  • Ahmad K, Ashfaq A, Khan ZI, Ashraf M, Akram NA, Yasmin S, Batool AI, Sher M, Shad HA, Khan A. 2016. Health risk assessment of heavy metals and metalloids via dietary intake of a potential vegetable (Coriandrum sativum L.) grown in contaminated water irrigated agricultural sites of Sargodha, Pakistan. Human And Ecological Risk Assessment: An International Journal. 22(3):597–610. doi: 10.1080/10807039.2015.1095630.
  • Ahmad K, Ashfaq A, Khan ZI, Bashir H, Sohail M, Mehmood N, Dogan Y. 2018. Metal accumulation in Raphanus sativus and Brassica rapa: an assessment of potential health risk for inhabitants in Punjab, Pakistan. Environ Sci Pollut Res. 25(17):16676–16685. doi: 10.1007/s11356-018-1868-7.
  • Ahmad MSA, Ashraf M. 2012. Essential roles and hazardous effects of nickel in plants. Rev Environ Contam Toxicol. 20:125–167.
  • Ahmad JU, Goni M. 2010. Heavy metal contamination in water, soil, and vegetables of the industrial areas in Dhaka, Bangladesh. Environ Monit Assess. 166(1):347–357. doi: 10.1007/s10661-009-1006-6.
  • Ahmad K, Khan ZI, Ashfaq A, Ashraf M, Akram NA, Sher M, Shad HA, Tufarelli V, Lonigro A, Fracchiolla M. 2017. Uptake of hazardous elements by spring onion (allium fistulosum L.) from soil irrigated with different types of water and possible health risk. Environ Earth Sci. 76(8):1–8. doi: 10.1007/s12665-017-6645-2.
  • Ahmad K, Khan ZI, Ashfaq A, Ashraf M, Akram NA, Yasmin S, Sher M. 2015. Assessment of heavy metals and metalloids in Solanum tuberosum and Pisum sativum irrigated with urban wastewater in the suburbs of Sargodha City, Pakistan. Human And Ecological Risk Assessment: An International Journal. 21(4):1109–1122. doi: 10.1080/10807039.2014.962344.
  • Ahmad K, Khan ZI, Ashfaq A, Ashraf M, Yasmin S. 2014. Assessment of heavy metal and metalloid levels in spinach (Spinacia oleracea L.) grown in wastewater irrigated agricultural soil of Sargodha, Pakistan. Pak J Bot. 46(5):1805–1810.
  • Ahmad K, Khan ZI, Yasmin S, Akram NA, Ashraf M, Ashfaq A, Fardous A. 2016. Accumulation of metals and metalloids in radish (Raphanus sativus L.) and spinach (spinacea oleracea L.) irrigated with domestic wastewater in the peri-urban areas of Khushab City, Pakistan. Human And Ecological Risk Assessment: An International Journal. 22(1):15–27. doi: 10.1080/10807039.2015.1045831.
  • Akoto O, Addo D, Baidoo E, Agyapong EA, Apau J, Fei-Baffoe B. 2015. Heavy metal accumulation in untreated wastewater-irrigated soil and lettuce (Lactuca sativa). Environ Earth Sci. 74(7):6193–6198. doi: 10.1007/s12665-015-4640-z.
  • Alamgir A, Khan MA, Shaukat SS, Shahab S, Mahmood K. 2016. Estimation of environmental pollutants in vegetables. Int J Veg Sc. 22(2):161–169. doi: 10.1080/19315260.2014.984263.
  • Alemu T, Mekonnen A, Leta S. 2019. Integrated tannery wastewater treatment for effluent reuse for irrigation: encouraging water efficiency and sustainable development in developing countries. J Water Process Eng. 30:100514. doi: 10.1016/j.jwpe.2017.10.014.
  • AlGhamdi FA, Hassan AB, AlFaris NA, AlTamimi JZ. 2023. Effect of traditional household processing techniques on phenolic compounds, antioxidants activity and γ-aminobutyric acid of cowpea (Vigna unguiculata) pods. Ital J Food Sci. 35(2):71–79. doi: 10.15586/ijfs.v35i2.2327.
  • Al-Lahham O, El Assi N, Fayyad M. 2007. Translocation of heavy metals to tomato (Solanum lycopersicom L.) fruit irrigated with treated wastewater. Sci Hortic (Amsterdam). 113(3):250–254. doi: 10.1016/j.scienta.2007.03.017.
  • Al-Nakshabandi G, Saqqar M, Shatanawi M, Fayyad M, Al-Horani H. 1997. Some environmental problems associated with the use of treated wastewater for irrigation in Jordan. Agr Water Manage. 34(1):81–94. doi: 10.1016/S0378-3774(96)01287-5.
  • Alnour TM, Ahmed-Abakur EH, Elssaig EH, Abuduhier FM, Ullah MF. 2022. Antimicrobial synergistic effects of dietary flavonoids rutin and quercetin in combination with antibiotics gentamicin and ceftriaxone against E. coli (MDR) and P. mirabilis (XDR) strains isolated from human infections: implications for food–medicine interactions. Ital J Food Sci. 34(2):34–42.
  • Alturiqi AS, Albedair LA, Ali MH. 2020. Health risk assessment of heavy metals in irrigation water, soil and vegetables from different farms in Riyadh district, Saudi Arabia. J Elem. 25:25–36.
  • Anastopoulos I, Ighalo JO, Igwegbe CA, Giannakoudakis DA, Triantafyllidis KS, Pashalidis I, Kalderis D. 2021. Sunflower-biomass derived adsorbents for toxic/heavy metals removal from (waste) water. J Mol Liq. 342:117540. doi: 10.1016/j.molliq.2021.117540.
  • Anjum NA, Adam V, Kizek R, Duarte AC, Pereira E, Iqbal M, Lukatkin AS, Ahmad I. 2015. Nanoscale copper in the soil–plant system–toxicity and underlying potential mechanisms. Environ Res. 138:306–325. doi: 10.1016/j.envres.2015.02.019.
  • Anwar S, Nawaz MF, Gul S, Rizwan M, Ali S, Kareem A. 2016. Uptake and distribution of minerals and heavy metals in commonly grown leafy vegetable species irrigated with sewage water. Environ Monit Assess. 188(9):541. doi: 10.1007/s10661-016-5560-4.
  • Aranega JP, Oliveira CA. 2022. Occurrence of mycotoxins in pastures: a systematic review. Qual Assur Saf Crops Foods. 14(3):135–144. doi: 10.15586/qas.v14i3.1079.
  • Arora M, Kiran B, Rani S, Rani A, Kaur B, Mittal N. 2008. Heavy metal accumulation in vegetables irrigated with water from different sources. Food Chem. 111(4):811–815. doi: 10.1016/j.foodchem.2008.04.049.
  • Asdeo A, Loonker S. 2011. A comparative analysis of trace metals in vegetables. Research Journal Of Environmental Toxicology. 5(2):125–132. doi: 10.3923/rjet.2011.125.132.
  • Atamaleki A, Yazdanbakhsh A, Fakhri Y, Mahdipour F, Khodakarim S, Mousavi Khaneghah A. 2019. The concentration of potentially toxic elements (PTEs) in the onion and tomato irrigated by wastewater: a systematic review; meta-analysis and health risk assessment. Food Res Int. 125:108518. doi: 10.1016/j.foodres.2019.108518.
  • Atamaleki A, Yazdanbakhsh A, Fakhri Y, Salem A, Ghorbanian M, Mousavi Khaneghah A. 2020. A systematic review and meta-analysis to investigate the correlation vegetable irrigation with wastewater and concentration of potentially toxic elements (PTES): a case study of spinach (Spinacia oleracea) and radish (Raphanus raphanistrum subsp. sativus). Biological Trace Element Research.
  • Atamaleki A, Yazdanbakhsh A, Fakhri Y, Salem A, Ghorbanian M, Mousavi Khaneghah A. 2021. A systematic review and meta-analysis to investigate the correlation vegetable irrigation with wastewater and concentration of potentially toxic elements (PTES): a case study of spinach (Spinacia oleracea) and radish (Raphanus raphanistrum subsp. sativus). Biol Trace Elem Res. 199(2):792–799. doi: 10.1007/s12011-020-02181-0.
  • Atamaleki A, Yazdanbakhsh A, Fallah S, Hesami M, Neshat A, Fakhri Y. 2021. Accumulation of potentially harmful elements (PHEs) in lettuce (Lactuca sativa L.) and coriander (Coriandrum sativum L.) irrigated with wastewater: a systematic review and meta-analysis and probabilistic health risk assessment. Environ Sci Pollut Res. 28(11):13072–13082. doi: 10.1007/s11356-020-12105-z.
  • Atamaleki A, Yazdanbakhsh A, Gholizadeh A, Naimi N, Karimi P, Thai VN, Fakhri Y. 2021. Concentration of potentially harmful elements (PHEs) in eggplant vegetable (Solanum melongena) irrigated with wastewater: a systematic review and meta-analysis and probabilistic health risk assessment. Int J Environ Res. 32(7):1–13. doi: 10.1080/09603123.2021.1887461.
  • Atamaleki A, Yazdanbakhsh A, Gholizadeh A, Naimi N, Karimi P, Thai VN, Fakhri Y. 2022. Concentration of potentially harmful elements (PHEs) in eggplant vegetable (Solanum melongena) irrigated with wastewater: a systematic review and meta-analysis and probabilistic health risk assessment. Int J Environ Res. 32(7):1419–1431. doi: 10.1080/09603123.2021.1887461.
  • Audu A, Lawal A. 2006. Variation in metal contents of plants in vegetable garden sites in Kano Metropolis. J Appl Sci Environ Manag. 10(2). doi: 10.4314/jasem.v10i2.43680.
  • Avci H, Deveci T. 2013. Assessment of trace element concentrations in soil and plants from cropland irrigated with wastewater. Ecotoxicol Environ Saf. 98:283–291. doi: 10.1016/j.ecoenv.2013.08.013.
  • Awa SH, Hadibarata T. 2020. Removal of heavy metals in contaminated soil by phytoremediation mechanism: a review. Water Air Soil Pollut. 231(2):1–15. doi: 10.1007/s11270-020-4426-0.
  • Bahiru DB. 2021. Assessment of some heavy metals contamination in some vegetables (tomato, cabbage, lettuce and onion) in Ethiopia: a review. Ame j Environ protection. 10(2):53–58. doi: 10.11648/j.ajep.20211002.12.
  • Bakopoulou S, Emmanouil C, Kungolos A. 2011. Assessment of wastewater effluent quality in Thessaly region, Greece, for determining its irrigation reuse potential. Ecotox Environ Safe. 74(2):188–194. doi: 10.1016/j.ecoenv.2010.06.022.
  • Balkhair KS, Ashraf MA. 2016. Field accumulation risks of heavy metals in soil and vegetable crop irrigated with sewage water in western region of Saudi Arabia. Saudi J Biol Sci. 23(1):S32–S44. doi: 10.1016/j.sjbs.2015.09.023.
  • Bangar SP, Sharma N, Bhardwaj A, Phimolsiripol Y. 2022. Lactic acid bacteria: a bio-green preservative against mycotoxins for food safety and shelf-life extension. Qual Assur Saf Crops Foods. 14(2):13–31. doi: 10.15586/qas.v14i2.1014.
  • Basso ABG, Ali S, Corassin CH, Rosim RE, de Oliveria CAF. 2023. Individual and combined decontamination effect of fermentation and ultrasound on aflatoxin B1 in wheat-based doughs: a preliminary study. Qual Assur Saf Crops Foods. 15(3):96–103. doi: 10.15586/qas.v15i3.1244.
  • Becerra-Castro C, Lopes AR, Vaz-Moreira I, Silva EF, Manaia CM, Nunes OC. 2015. Wastewater reuse in irrigation: a microbiological perspective on implications in soil fertility and human and environmental health. Environ Int. 75:117–135. doi: 10.1016/j.envint.2014.11.001.
  • Beneduce L, Gatta G, Bevilacqua A, Libutti A, Tarantino E, Bellucci M, Troiano E, Spano G. 2017. Impact of the reusing of food manufacturing wastewater for irrigation in a closed system on the microbiological quality of the food crops. Int J Food Microbiol. 260:51–58. doi: 10.1016/j.ijfoodmicro.2017.08.009.
  • Bhalerao SA, Sharma AS, Poojari AC. 2015. Toxicity of nickel in plants. International Journal Of Pure And Applied Bioscience. 3(2):345–355.
  • Brunetto G, Rosa DJ, Ambrosini VG, Heinzen J, Ferreira PA, Ceretta CA, Soares CR, Melo GW, Soriani HH, Nicoloso FT. 2019. Use of phosphorus fertilization and mycorrhization as strategies for reducing copper toxicity in young grapevines. Sci Hortic (Amsterdam). 248:176–183. doi: 10.1016/j.scienta.2019.01.026.
  • Bu Q, Li Q, Zhang H, Cao H, Gong W, Zhang X, Ling K, Cao Y. 2020. Concentrations, spatial distributions, and sources of heavy metals in surface soils of the Coal Mining City Wuhai, China. J Chem. 2020:1–10. doi: 10.1155/2020/4705954.
  • Cai S, Zeng B, Li C. 2023. Potential health risk assessment of metals in the muscle of seven wild fish species from the wujiangdu reservoir, China. Qual Assur Saf Crops Foods. 15(1):73–83. doi: 10.15586/qas.v15i1.1121.
  • Cao C, Zhang Q, Ma Z-B, Wang X-M, Chen H, Wang J-J. 2018. Fractionation and mobility risks of heavy metals and metalloids in wastewater-irrigated agricultural soils from greenhouses and fields in Gansu, China. Geoderma. 328:1–9. doi: 10.1016/j.geoderma.2018.05.001.
  • Castro E, Manas P, De las Heras J. 2009. A comparison of the application of different waste products to a lettuce crop: effects on plant and soil properties. Sci Hortic (Amsterdam). 123(2):148–155. doi: 10.1016/j.scienta.2009.08.013.
  • Chaari M, Elhadef K, Akermi S, Hlima HB, Fourati M, Mtibaa AC, D’Amore T, Ali DS, Mellouli L, Ennouri M, et al. 2023. Potentials of beetroot (beta vulgaris L.) peel extract for quality enhancement of refrigerated beef meat. Qual Assur Saf Crops Foods. 15(4):1–15. doi:10.15586/qas.v15i4.1376.
  • Chary NS, Kamala C, Raj DSS. 2008. Assessing risk of heavy metals from consuming food grown on sewage irrigated soils and food chain transfer. Ecotox Environ Safe. 69(3):513–524. doi: 10.1016/j.ecoenv.2007.04.013.
  • Chen Y, Chen L, Zhou Q. 2021. Genetische Assoziation zwischen eNOS-Gen-Polymorphismen und dem Risiko für Karotisarteriosklerose. Herz. 46(S2):253–264. doi: 10.1007/s00059-020-04995-z.
  • Cherfi A, Achour M, Cherfi M, Otmani S, Morsli A. 2015. Health risk assessment of heavy metals through consumption of vegetables irrigated with reclaimed urban wastewater in Algeria. Process Saf Environ Prot. 98:245–252. doi: 10.1016/j.psep.2015.08.004.
  • Cheshmazar E, Arfaeinia H, Karimyan K, Sharafi H, Hashemi SE. 2018. Dataset for effect comparison of irrigation by wastewater and ground water on amount of heavy metals in soil and vegetables: accumulation, transfer factor and health risk assessment. Data Brief. 18:1702–1710. doi: 10.1016/j.dib.2018.04.108.
  • Christou A, Maratheftis G, Eliadou E, Michael C, Hapeshi E, Fatta-Kassinos D. 2014. Impact assessment of the reuse of two discrete treated wastewaters for the irrigation of tomato crop on the soil geochemical properties, fruit safety and crop productivity. Agric Ecosyst Environ. 192:105–114. doi: 10.1016/j.agee.2014.04.007.
  • Chu Z, Yang Z, Wang Y, Sun L, Yang W, Yang L, Gao Y. 2019. Assessment of heavy metal contamination from penguins and anthropogenic activities on Fildes Peninsula and Ardley Island, Antarctic. Sci Total Environ. 646:951–957. doi: 10.1016/j.scitotenv.2018.07.152.
  • Courault D, Albert I, Perelle S, Fraisse A, Renault P, Salemkour A, Amato P. 2017. Assessment and risk modeling of airborne enteric viruses emitted from wastewater reused for irrigation. Sci Total Environ. 592:512–526. doi: 10.1016/j.scitotenv.2017.03.105.
  • Cui Y, Wang X, Lin F, Li W, Zhao Y, Zhu F, Yang H, Rao M, Liang H, Dai M. 2022. MiR-29a-3p improves acute lung injury by reducing alveolar epithelial cell PANoptosis. Aging Dis. 13(3):899. doi: 10.14336/AD.2021.1023.
  • Ćwieląg-Drabek M, Piekut A, Gut K, Grabowski M. 2020. Risk of cadmium, lead and zinc exposure from consumption of vegetables produced in areas with mining and smelting past. Sci Rep. 10(1):1–9. doi: 10.1038/s41598-020-60386-8.
  • Delbari A, Kulkarni D. 2013. Determination of heavy metal pollution in vegetables grown along the roadside in Tehran-Iran. Annals Of Biological Research. 4(2):224–233.
  • Demir AD, Sahin U. 2017. Effects of different irrigation practices using treated wastewater on tomato yields, quality, water productivity, and soil and fruit mineral contents. Environ Sci Pollut Res. 24(32):24856–24879. doi: 10.1007/s11356-017-0139-3.
  • Desai M, Haigh M, Walkington H. 2019. Phytoremediation: metal decontamination of soils after the sequential forestation of former opencast coal land. Sci Total Environ. 656:670–680. doi: 10.1016/j.scitotenv.2018.11.327.
  • Diarra I, Prasad S. 2021. The current state of heavy metal pollution in Pacific Island Countries: a review. Appl Spectrosc Rev. 56(1):27–51. doi: 10.1080/05704928.2020.1719130.
  • Dong WQY, Cui Y, Liu X. 2001. Instances of soil and crop heavy metal contamination in China. Soil Sediment Contam. 10(5):497–510. doi: 10.1080/20015891109392.
  • Drechsel P, Bahri A, Raschid-Sally L, Redwood M. 2010. Wastewater irrigation and health: assessing and mitigating risk in low-income countries. London, UK: IWMI.
  • D’yakova N, Samylina I, Slivkin A, Gaponov S, Myndra A. 2018. Estimated heavy-metal and arsenic contents in medicinal plant raw materials of the Voronezh region. Pharm Chem J. 52(3):220–223. doi: 10.1007/s11094-018-1797-2.
  • Elgallal M, Fletcher L, Evans B. 2016. Assessment of potential risks associated with chemicals in wastewater used for irrigation in arid and semiarid zones: a review. Agr Water Manage. 177:419–431. doi: 10.1016/j.agwat.2016.08.027.
  • El-Harbawi M, Abd Raman AA, Al-Mubaddel F. 2020. Development of a chemical health risk assessment tool for health risk assessment from exposure to hazardous chemicals. Biomedical Journal Of Scientific & Technical Research. 28(3):21715–21726. doi: 10.26717/BJSTR.2020.28.004669.
  • Eliku T, Leta S. 2016. Assessment of heavy metal contamination in vegetables grown using paper mill wastewater in Wonji Gefersa, Ethiopia. Bull Environ Contam Toxicol. 97(5):714–720. doi: 10.1007/s00128-016-1915-3.
  • EPA. 2011. Exposure factors handbook. 2011. EPA/600/R-09. Boston USA: Environmental Protection Agency.
  • EPA U. 2000. Risk-based concentration table. Philadelphia PA: United States Environmental Protection Agency, Washington DC.
  • Fan Y, Chen J, Wang Z, Tan T, Li S, Li J, Wang B, Zhang J, Cheng Y, Wu X. 2019. Soybean (glycine max L. Merr.) seedlings response to shading: leaf structure, photosynthesis and proteomic analysis. BMC Plant Biol. 19(1):1–12. doi: 10.1186/s12870-019-1633-1.
  • Farahat E, Linderholm HW. 2015. The effect of long-term wastewater irrigation on accumulation and transfer of heavy metals in Cupressus sempervirens leaves and adjacent soils. Sci Total Environ. 512-513:1–7. doi: 10.1016/j.scitotenv.2015.01.032.
  • Fathabad AE, Shariatifar N, Moazzen M, Nazmara S, Fakhri Y, Alimohammadi M, Azari A, Khaneghah AM. 2018. Determination of heavy metal content of processed fruit products from Tehran’s market using ICP-OES: a risk assessment study. Food Chem Toxicol. 115:436–446. doi: 10.1016/j.fct.2018.03.044.
  • Gaggero E, Calza P, Fabbri D, Fusconi A, Mucciarelli M, Bordiglia G, Abollino O, Malandrino M. 2020. Assessment and mitigation of heavy metals uptake by edible vegetables grown in a turin contaminated soil used as vegetable garden. Appl Sci. 10(13):4483. doi: 10.3390/app10134483.
  • Gao L, Huang X, Wang P, Chen Z, Hao Q, Bai S, Tang S, Li C, Qin D. 2022. Concentrations and health risk assessment of 24 residual heavy metals in Chinese mitten crab (eriocheir sinensis). Qual Assur Saf Crops Foods. 14(1):82–91. doi: 10.15586/qas.v14i1.1034.
  • Gao P, Liang W, Zhao Q, Li H, Guan L, Li D. 2023. Effects of vitamins A, C, and D and zinc on urinary tract infections: a systematic review and meta-analysis. Qual Assur Saf Crops Foods. 15(3):88–95. doi: 10.15586/qas.v15i3.1292.
  • Gao Y, Shao G, Wu S, Xiaojun W, Lu J, Cui J. 2021. Changes in soil salinity under treated wastewater irrigation: a meta-analysis. Agr Water Manage. 255:106986. doi: 10.1016/j.agwat.2021.106986.
  • Gatta G, Libutti A, Beneduce L, Gagliardi A, Disciglio G, Lonigro A, Tarantino E. 2016. Reuse of treated municipal wastewater for globe artichoke irrigation: assessment of effects on morpho-quantitative parameters and microbial safety of yield. Sci Hortic (Amsterdam). 213:55–65. doi: 10.1016/j.scienta.2016.10.011.
  • Geyik ÖG, Tekin-Cakmak ZH, Shamanin VP, Karasu S, Pototskaya IV, Shepelev SS, Chursin AS, Morgounov AI, Yaman M, Sagdic O. 2023. Effects of phenolic compounds of colored wheats on colorectal cancer cell lines. Qual Assur Saf Crops Foods. 15(4):21–31. doi: 10.15586/qas.v15i4.1354.
  • Guadie A, Yesigat A, Gatew S, Worku A, Liu W, Ajibade FO, Wang A. 2021. Evaluating the health risks of heavy metals from vegetables grown on soil irrigated with untreated and treated wastewater in Arba Minch, Ethiopia. Sci Total Environ. 761:143302. doi: 10.1016/j.scitotenv.2020.143302.
  • Gupta N, Khan D, Santra S. 2008. An assessment of heavy metal contamination in vegetables grown in wastewater-irrigated areas of titagarh, West Bengal, India. Bull Environ Contam Toxicol. 80(2):115–118. doi: 10.1007/s00128-007-9327-z.
  • Gupta N, Khan D, Santra S. 2010. Determination of public health hazard potential of wastewater reuse in crop production. World Review Of Science, Technology And Sustainable Development. 7(4):328–340. doi: 10.1504/WRSTSD.2010.032741.
  • Gupta N, Khan D, Santra S. 2012. Heavy metal accumulation in vegetables grown in a long-term wastewater-irrigated agricultural land of tropical India. Environ Monit Assess. 184(11):6673–6682. doi: 10.1007/s10661-011-2450-7.
  • Gupta S, Nayek S, Saha R, Satpati S. 2008. Assessment of heavy metal accumulation in macrophyte, agricultural soil, and crop plants adjacent to discharge zone of sponge iron factory. Environ Geol. 55(4):731–739. doi: 10.1007/s00254-007-1025-y.
  • Hezbullah M, Sultana S, Chakraborty S, Patwary M. 2016. Heavy metal contamination of food in a developing country like Bangladesh: an emerging threat to food safety. J Toxicol Environ Health Sci. 8(1):1–5. doi: 10.5897/JTEHS2016.0352.
  • Higgins J, Thompson SG. 2002. Quantifying heterogeneity in a meta‐analysis. Stat Med. 21(11):1539–1558. doi: 10.1002/sim.1186.
  • Husaini S, Zaidi J, Matiullah AM. 2011a. Appraisal of venomous metals in selected crops and vegetables from industrial areas of the Punjab Province. J Radioanal Nucl Chem. 290(3):535–541. doi: 10.1007/s10967-011-1287-4.
  • Husaini S, Zaidi J, Matiullah AM. 2011b. Assessment of the toxicity level of an industrial eco-system for its hazardous metals. J Radioanal Nucl Chem. 290(3):655–665. doi: 10.1007/s10967-011-1345-y.
  • Hussain A, Alamzeb S, Begum S. 2013. Accumulation of heavy metals in edible parts of vegetables irrigated with waste water and their daily intake to adults and children, District Mardan, Pakistan. Food Chem. 136(3–4):1515–1523. doi: 10.1016/j.foodchem.2012.09.058.
  • Hussain A, Priyadarshi M, Dubey S. 2019a. Experimental study on accumulation of heavy metals in vegetables irrigated with treated wastewater. Appl Water Sci. 9(5):1–11. doi: 10.1007/s13201-019-0999-4.
  • Hussain A, Priyadarshi M, Dubey S. 2019b. Experimental study on accumulation of heavy metals in vegetables irrigated with treated wastewater. Appl Water Sci. 9(5). doi: 10.1007/s13201-019-0999-4.
  • Hussain MI, Qureshi AS. 2020. Health risks of heavy metal exposure and microbial contamination through consumption of vegetables irrigated with treated wastewater at Dubai, UAE. Environ Sci Pollut Res. 27(10):11213–11226. doi: 10.1007/s11356-019-07522-8.
  • Hu L, Wang X, Zou Y, Wu D, Gao G, Zhong Z, Liu Y, Hu S, Fan H, Zhang B. 2022. Effects of inorganic and organic selenium intervention on resistance of radish to arsenic stress. Ital J Food Sci. 34(1):44–58. doi: 10.15586/ijfs.v34i1.2105.
  • Iqbal K, Shafiq T, Ahmed K. 2009. Comparative Study of Heavy Metals in selected vegetables collected from different sources: Heavy Metals in vegetables. Biological Sciences-PJSIR. 52(3):134–137.
  • Ismail F, Anjum M, Mamon A, Kazi T. 2011. Trace metal contents of vegetables and fruits of Hyderabad retail market. Pakistan J Nutrition. 10(4):365–372. doi: 10.3923/pjn.2011.365.372.
  • Jafari A, Ghaderpoori M, Kamarehi B, Abdipour H. 2019. Soil pollution evaluation and health risk assessment of heavy metals around Douroud cement factory, Iran. Environ Earth Sci. 78(8):1–9. doi: 10.1007/s12665-019-8220-5.
  • Jan FA, Ishaq M, Khan S, Ihsanullah I, Ahmad I, Shakirullah M. 2010. A comparative study of human health risks via consumption of food crops grown on wastewater irrigated soil (Peshawar) and relatively clean water irrigated soil (lower dir). J Hazard Mater. 179(1–3):612–621. doi: 10.1016/j.jhazmat.2010.03.047.
  • Jasim SY, Saththasivam J, Loganathan K, Ogunbiyi OO, Sarp S. 2016. Reuse of treated sewage effluent (TSE) in Qatar. J Water Process Eng. 11:174–182. doi: 10.1016/j.jwpe.2016.05.003.
  • Jiang F, Ren B, Hursthouse A, Deng R, Wang Z. 2019. Distribution, source identification, and ecological-health risks of potentially toxic elements (PTEs) in soil of thallium mine area (southwestern Guizhou, China). Environ Sci Pollut Res. 26(16):16556–16567. doi: 10.1007/s11356-019-04997-3.
  • Ji Y, Wu P, Zhang J, Zhang J, Zhou Y, Peng Y, Zhang S, Cai G, Gao G. 2018. Heavy metal accumulation, risk assessment and integrated biomarker responses of local vegetables: a case study along the Le’an river. Chemosphere. 199:361–371. doi: 10.1016/j.chemosphere.2018.02.045.
  • Kachout SS, Mansoura AB, Mechergui R, Leclerc JC, Rejeb MN, Ouerghi Z. 2012. Accumulation of Cu, Pb, Ni and Zn in the halophyte plant Atriplex grown on polluted soil. J Sci Food Agric. 92(2):336–342. doi: 10.1002/jsfa.4581.
  • Karimi P, Yazdanbakhsh A, Atamaleki A, Kariminejad F, Ahmadian M, Fallah S. 2021a. Global evaluation of potentially harmful elements (PHEs) in potato and carrot irrigated by wastewater: a systematic review, meta-analysis. And Health Risk Assessment %J Environmental Health Engineering And Management Journal [Review Article]. 8(4):245–255. eng. doi: 10.34172/EHEM.2021.28.
  • Karimi P, Yazdanbakhsh A, Atamaleki A, Kariminejad F, Ahmadian M, Fallah S. 2021b. Global evaluation of potentially harmful elements (PHEs) in potato and carrot irrigated by wastewater: a systematic review, meta-analysis, and health risk assessment. Environ Health Eng Manag. 8(4):245–255. doi: 10.34172/EHEM.2021.28.
  • Kaşıkçı MB, Bağdatlıoğlu N. 2022. Assessment of the bioaccessibility of phenolic compounds and antioxidant activity in raw and pickled white cabbage and gherkins. Ital J Food Sci. 34(4):1–10. doi: 10.15586/ijfs.v34i4.2267.
  • KHAN MJ. 2008. Waste water use in agriculture and heavy metal pollution in soil-plant system. J Chem Soc Pak. 30(3):425.
  • Khan ZI, Ahmad K, Akram NA, Mehmood N, Yasmeen S. 2017. Heavy metal contamination in water, soil and a potential vegetable garlic (Allium sativum L.) in Punjab, Pakistan. Pak J Bot. 49(2):547–552.
  • Khan ZI, Ahmad K, Yasmeen S, Akram NA, Ashraf M, Mehmood N. 2017. Potential health risk assessment of potato (Solanum tuberosum L.) grown on metal contaminated soils in the central zone of Punjab, Pakistan. Chemosphere. 166:157–162. doi: 10.1016/j.chemosphere.2016.09.064.
  • Khan S, Cao Q, Zheng Y, Huang Y, Zhu Y. 2008. Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Beijing, China. Environ Pollut. 152(3):686–692. doi: 10.1016/j.envpol.2007.06.056.
  • Khan MJ, Jan MT, Farhatullah N, Khan MA, Perveen S, Alam S, Jan AU. 2011. The effect of using waste water for tomato. Pak J Bot. 43(2):1033–1044.
  • Khan A, Javid S, Muhmood A, Mjeed T, Niaz A, Majeed A. 2013. Heavy metal status of soil and vegetables grown on peri-urban area of Lahore district. Soil Environ. 32(1):49–54.
  • Khan A, Khan S, Khan MA, Qamar Z, Waqas M. 2015. The uptake and bioaccumulation of heavy metals by food plants, their effects on plants nutrients, and associated health risk: a review. Environ Sci Pollut Res. 22(18):13772–13799. doi: 10.1007/s11356-015-4881-0.
  • Khan MU, Malik RN, Muhammad S. 2013. Human health risk from heavy metal via food crops consumption with wastewater irrigation practices in Pakistan. Chemosphere. 93(10):2230–2238. doi: 10.1016/j.chemosphere.2013.07.067.
  • Khan MA, Mehmood S, Ullah F, Khattak A, Zeb MA. 2017. Health risks assessment diagnosis of toxic chemicals (heavy metals) via food crops consumption irrigated with wastewater. Sains Malays. 46(6):917–924. doi: 10.17576/jsm-2017-4606-11.
  • Khan FSA, Mubarak NM, Tan YH, Khalid M, Karri RR, Walvekar R, Abdullah EC, Nizamuddin S, Mazari SA. 2021. A comprehensive review on magnetic carbon nanotubes and carbon nanotube-based buckypaper for removal of heavy metals and dyes. J Hazard Mater. 413:125375. doi: 10.1016/j.jhazmat.2021.125375.
  • Khanum K, Baqar M, Qadir A, Mumtaz M, Tahir A, Jamil N, Mahmood A. 2017. Heavy metal toxicity and human health risk surveillances of wastewater irrigated vegetables in Lahore District, Pakistan. Carpathian Journal Of Earth And Environmental Sciences. 12(2):403–412.
  • Kim HK, Jang TI, Kim SM, Park SW. 2014. Impact of domestic wastewater irrigation on heavy metal contamination in soil and vegetables [article]. Environ Earth Sci. 73(5):2377–2383. doi: 10.1007/s12665-014-3581-2.
  • Kim H, Jang T, Kim S, Park S. 2015. Impact of domestic wastewater irrigation on heavy metal contamination in soil and vegetables. Environ Earth Sci. 73(5):2377–2383. doi: 10.1007/s12665-014-3581-2.
  • Kiziloglu FM, Turan M, Sahin U, Kuslu Y, Dursun A. 2008. Effects of untreated and treated wastewater irrigation on some chemical properties of cauliflower (Brassica olerecea L. var. botrytis) and red cabbage (Brassica olerecea L. var. rubra) grown on calcareous soil in Turkey. Agr Water Manage. 95(6):716–724. doi: 10.1016/j.agwat.2008.01.008.
  • Kumar S, Prasad S, Yadav KK, Shrivastava M, Gupta N, Nagar S, Bach Q-V, Kamyab H, Khan SA, Yadav S. 2019. Hazardous heavy metals contamination of vegetables and food chain: role of sustainable remediation approaches-A review. Environ Res. 179:108792. doi: 10.1016/j.envres.2019.108792.
  • Kumar D, Singh DP, Barman SC, Kumar N. 2016. Heavy Metal and Their Regulation in Plant System: an overview. In: Singh A, Prasad S Singh R, editors Plant responses to Xenobiotics. Singapore: Springer Singapore; pp. 19–38.
  • Kuroki T, Watanabe Y, Teranishi H, Izumiyama S, Amemura-Maekawa J, Kura F. 2017. Legionella prevalence and risk of legionellosis in Japanese households. Epidemiol Infect. 145(7):1398–1408. doi: 10.1017/S0950268817000036.
  • Lange B, van der Ent A, Baker AJM, Echevarria G, Mahy G, Malaisse F, Meerts P, Pourret O, Verbruggen N, Faucon MP. 2017. Copper and cobalt accumulation in plants: a critical assessment of the current state of knowledge. New Phytol. 213(2):537–551. doi: 10.1111/nph.14175.
  • Lan T, Hu Y, Cheng L, Chen L, Guan X, Yang Y, Guo Y, Pan J. 2022. Floods and diarrheal morbidity: evidence on the relationship, effect modifiers, and attributable risk from Sichuan Province, China. J Glob Health. 12:12. doi: 10.7189/jogh.12.11007.
  • Leblebici Z, Kar M. 2018. Heavy metals accumulation in vegetables ırrigated with different water sources and their human daily intake in Nevsehir. J Agric Sci Technol. 25:21–29 .
  • Lee W-L, Huang J-Y, Shyur L-F. 2013. Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms. Oxid Med Cell Longev. 2013:1–22. doi: 10.1155/2013/925804.
  • Li J, Chen Y, Xiang Q, Xiang J, Tang Y, Tang L. 2020. 5HTTLPR polymorphism and postpartum depression risk: a meta-analysis. Med. 99(39):e22319. doi: 10.1097/MD.0000000000022319.
  • Li X, Jing R, Wang L, Wu N, Guo Z. 2023. Role of arbuscular mycorrhizal fungi in cadmium tolerance in rice (Oryza sativa L): a meta-analysis. Qual Assur Saf Crops Foods. 15(2):59–70. doi: 10.15586/qas.v15i2.1182.
  • Li N, Kang Y, Pan W, Zeng L, Zhang Q, Luo J. 2015. Concentration and transportation of heavy metals in vegetables and risk assessment of human exposure to bioaccessible heavy metals in soil near a waste-incinerator site, South China. Sci Total Environ. 521:144–151. doi: 10.1016/j.scitotenv.2015.03.081.
  • Li J, Luo J, Liu L, Fu H, Tang L. 2018. The genetic association between apolipoprotein E gene polymorphism and Parkinson disease: a meta-analysis of 47 studies. Med. 97(43):e12884. doi: 10.1097/MD.0000000000012884.
  • Lim JT, Tan YQ, Valeri L, Lee J, Geok PP, Chia SE, Ong CN, Seow WJ. 2019. Association between serum heavy metals and prostate cancer risk–A multiple metal analysis. Environ Int. 132:105109. doi: 10.1016/j.envint.2019.105109.
  • Lin C, Lu W, Wu Y. 2005. Agricultural soils irrigated with acidic mine water: acidity, heavy metals, and crop contamination. Soil Res. 43(7):819–826. doi: 10.1071/SR04148.
  • Liu Y-M, Liu D-Y, Zhang W, Chen X-X, Zhao Q-Y, Chen X-P, Zou C-Q. 2020. Health risk assessment of heavy metals (zn, Cu, Cd, Pb, as and Cr) in wheat grain receiving repeated Zn fertilizers. Environ Pollut. 257:113581. doi: 10.1016/j.envpol.2019.113581.
  • Liu W-H, Zhao J-Z, Ouyang Z-Y, Söderlund L, Liu G-H. 2005. Impacts of sewage irrigation on heavy metal distribution and contamination in Beijing, China. Environ Int. 31(6):805–812. doi: 10.1016/j.envint.2005.05.042.
  • Li X, Wang X, Chen Y, Yang X, Cui Z. 2019. Optimization of combined phytoremediation for heavy metal contaminated mine tailings by a field-scale orthogonal experiment. Ecotox Environ Safe. 168:1–8. doi: 10.1016/j.ecoenv.2018.10.012.
  • Lonigro A, Rubino P, Brandonisio O, Spinelli R, Pollice A, Laera G. 2007. Vegetable crop irrigation with tertiary filtered municipal wastewater. Plant Biosyst - Int J Dealing Aspects Plant Biosyst. 141(2):275–281. doi: 10.1080/11263500701402016.
  • Lorestani B, Merrikhpour H, Cheraghi M. 2020. Assessment of heavy metals concentration in groundwater and their associated health risks near an industrial area. Environ Health Eng Manag. 7(2):67–77. doi: 10.34172/EHEM.2020.09.
  • Luo C, Sun J, Tan Y, Xiong L, Peng B, Peng G, Bai X. 2022. Comparison of the health risks associated with exposure to toxic metals and metalloids following consumption of freshwater catches in China. Qual Assur Saf Crops Foods. 14(4):1–12. doi: 10.15586/qas.v14i4.1117.
  • Mahmood A, Malik RN. 2014. Human health risk assessment of heavy metals via consumption of contaminated vegetables collected from different irrigation sources in Lahore, Pakistan. Arab J Chem. 7(1):91–99. doi: 10.1016/j.arabjc.2013.07.002.
  • Maimon A, Khairiah J, Ahmad M, Aminah A, Ismail B. 2009. Comparative accumulation of heavy metals in selected vegetables, their availability and correlation in lithogenic and nonlithogenic fractions of soils from some agricultural areas in Malaysia. Adv Environ Biol. 3:314–321.
  • Manzoor J, Sharma M, Wani KA. 2018. Heavy metals in vegetables and their impact on the nutrient quality of vegetables: a review. J Plant Nutr. 41(13):1744–1763. doi: 10.1080/01904167.2018.1462382.
  • Mapanda F, Mangwayana E, Nyamangara J, Giller K. 2005. The effect of long-term irrigation using wastewater on heavy metal contents of soils under vegetables in Harare, Zimbabwe. Agric Ecosyst Environ. 107(2–3):151–165. doi: 10.1016/j.agee.2004.11.005.
  • Marbaniang D, Baruah P, Decruse R, Dkhar E, Diengdoh D, Nongpiur C. 2012. Study of the trace metal concentration in some local vegetables available in Shillong City, Meghlaya, India. Int J Environ Prot. 2:24–28.
  • Masindi V, Muedi KL. 2018. Environmental contamination by heavy metals. Heavy met. 10:115–132.
  • Mateo-Sagasta J, Raschid-Sally L, Thebo A. 2015. Global wastewater and sludge production, treatment and use. Wastewater. New York City, USA: Springer; pp. 15–38.
  • McCally M. 2002. Life support: the environment and human health. Cambridge, USA: MIT press.
  • Md AK, Bal RS, Shigenao K. 2011. Fractionation and mobility of cadmium, lead and zinc in some contaminated and non-contaminated soils of Japan. Journal Of Soil Science And Environmental Management. 2(9):241–249.
  • mFood Administration D. 2012. Guidance for industry: estimating dietary intake of substances in food. J Food Drug Anal. 5:15–23.
  • Milićević T, Relić D, Urošević MA, Vuković G, Škrivanj S, Samson R, Popović A. 2018. Integrated approach to environmental pollution investigation – spatial and temporal patterns of potentially toxic elements and magnetic particles in vineyard through the entire grapevine season. Ecotox Environ Safe. 163:245–254. doi: 10.1016/j.ecoenv.2018.07.078.
  • Mishra A, Tripathi BD. 2008. Heavy metal contamination of soil, and bioaccumulation in vegetables irrigated with treated waste water in the tropical city of Varanasi, India. Toxicol Environ Chem. 90(5):861–871. doi: 10.1080/02772240701740197.
  • Moreno‐Caselles J, Moral R, Perez‐Murcia MD, Perez‐Espinosa A, Paredes C, Agulló E. 2005. Fe, Cu, Mn, and Zn input and availability in calcareous soils amended with the solid phase of pig slurry. Commun Soil Sci Plan. 36(4–6):525–534. doi: 10.1081/CSS-200043279.
  • Mukhametov A, Chulenyov A, Kazak A, Semenycheva I. 2023. Physicochemical and microbiological analysis of goose meat. Qual Assur Saf Crops Foods. 15(2):49–58. doi: 10.15586/qas.v15i2.1200.
  • Murtaza G, Usman Y, Niazi NK, Usman M, Hussain T. 2017. Bioaccumulation of potentially toxic elements in cereal and legume crops: a review. CLEAN–Soil, Air, Water. 45(12):1700548. doi: 10.1002/clen.201700548.
  • Naaz S, Pandey S. 2010. Effects of industrial waste water on heavy metal accumulation, growth and biochemical responses of lettuce (Lactuca sativa L.). J Environ Biol. 31(3):273.
  • Nankishore A. 2014. Heavy metal levels in leafy vegetables from selected markets in Guyana. J Agric Technol. 10(3):651–663.
  • Nayek S, Gupta S, Saha R. 2010. Metal accumulation and its effects in relation to biochemical response of vegetables irrigated with metal contaminated water and wastewater. J Hazard Mater. 178(1–3):588–595. doi: 10.1016/j.jhazmat.2010.01.126.
  • Nie G, Tu T, Hu L, Wu L, Zhou Y. 2023. Accumulation characteristics and evaluation of heavy metals in soils and vegetables of plastic-covered sheds in typical red soil areas of China. Qual Assur Saf Crops Foods. 15(3):22–35. doi: 10.15586/qas.v15i3.1222.
  • Nikaido M, Tonani KA, Julião FC, Trevilato TM, Takayanagui AM, Sanches SM, Domingo JL, Segura-Muñoz SI. 2010. Analysis of bacteria, parasites, and heavy metals in lettuce (Lactuca sativa) and rocket salad (eruca sativa L.) irrigated with treated effluent from a biological wastewater treatment plant. Biol Trace Elem Res. 134(3):342–351. doi: 10.1007/s12011-009-8477-8.
  • Njuguna SM, Makokha VA, Yan X, Gituru RW, Wang Q, Wang J. 2019. Health risk assessment by consumption of vegetables irrigated with reclaimed waste water: a case study in Thika (Kenya). J Environ Manage. 231:576–581. doi: 10.1016/j.jenvman.2018.10.088.
  • Nkwunonwo UC, Odika PO, Onyia NI. 2020. A review of the health implications of heavy metals in food chain in Nigeria. Sci World J. 2020:1–11. doi: 10.1155/2020/6594109.
  • Onyeaka H, Anumudu CK, Okolo CA, Anyogu A, Odeyemi O, Bassey AP. 2022. A review of the top 100 most cited papers on food safety. Qual Assur Saf Crops Foods. 14(4):91–104. doi: 10.15586/qas.v14i4.1124.
  • Organization WH. 2006. WHO guidelines for the safe use of wasterwater excreta and greywater. Vol. 1. Geneva, Switzerland: World Health Organization.
  • Özlü H, Çevik B, Atasever M, Sarıalioğlu MF, Polat BA. 2023. Investigation of meat species adulteration in beef-based meat products via real-time PCR in Türkiye. Qual Assur Saf Crops Foods. 15(4):42–48. doi: 10.15586/qas.v15i4.1374.
  • Palansooriya KN, Shaheen SM, Chen SS, Tsang DC, Hashimoto Y, Hou D, Bolan NS, Rinklebe J, Ok YS. 2020. Soil amendments for immobilization of potentially toxic elements in contaminated soils: a critical review. Environ Int. 134:105046. doi: 10.1016/j.envint.2019.105046.
  • Pal S, Singh HB, Rakshit A. 2013. Potential of different crop species for nickel and cadmium phytoremediation in peri-urban areas of Varanasi district (India) with more than twenty years of wastewater irrigation history. Ital J Agronomy. 8(1):e8–e8. doi: 10.4081/ija.2013.e8.
  • Pedrero F, Kalavrouziotis I, Alarcón JJ, Koukoulakis P, Asano T. 2010. Use of treated municipal wastewater in irrigated agriculture—review of some practices in Spain and Greece. Agr Water Manage. 97(9):1233–1241. doi: 10.1016/j.agwat.2010.03.003.
  • Ping L, Zhao H-J, Wang L-L, Liu Z-H, Wei J-L, Wang Y-Q, Jiang L-H, Liang D, Zhang Y-F. 2011. Analysis of heavy metal sources for vegetable soils from Shandong Province, China. Agr Sci China. 10(1):109–119. doi: 10.1016/S1671-2927(11)60313-1.
  • Ponting J, Kelly TJ, Verhoef A, Watts MJ, Sizmur T. 2021. The impact of increased flooding occurrence on the mobility of potentially toxic elements in floodplain soil–A review. Sci Total Environ. 754:142040. doi: 10.1016/j.scitotenv.2020.142040.
  • Psarras G, Chartzoulakis K, Kasapakis I, Kloppmann W. 2012. Effect of different irrigation techniques and water qualities on yield, fruit quality and health risks of tomato plants. In: VII International Symposium on Irrigation of Horticultural Crops 1038.
  • Qu L, Huang H, Xia F, Liu Y, Dahlgren RA, Zhang M, Mei K. 2018. Risk analysis of heavy metal concentration in surface waters across the rural-urban interface of the Wen-Rui Tang River, China. Environ Pollut. 237:639–649. doi: 10.1016/j.envpol.2018.02.020.
  • Qureshi AS, Hussain MI, Ismail S, Khan QM. 2016. Evaluating heavy metal accumulation and potential health risks in vegetables irrigated with treated wastewater. Chemosphere. 163:54–61. doi: 10.1016/j.chemosphere.2016.07.073.
  • Qu B, Song J, Yuan H, Li X, Li N, Duan L. 2018. Intensive anthropogenic activities had affected Daya Bay in South China Sea since the 1980s: evidence from heavy metal contaminations. Mar Pollut Bull. 135:318–331. doi: 10.1016/j.marpolbul.2018.07.011.
  • Rai PK, Lee SS, Zhang M, Tsang YF, Kim K-H. 2019. Heavy metals in food crops: health risks, fate, mechanisms, and management. Environ Int. 125:365–385. doi: 10.1016/j.envint.2019.01.067.
  • Rai PK, Tripathi B. 2008. Heavy metals in industrial wastewater, soil and vegetables in Lohta village, India. Toxicological And Environ Chemistry. 90(2):247–257. doi: 10.1080/02772240701458584.
  • Raja S, Cheema HMN, Babar S, Khan AA, Murtaza G, Aslam U. 2015. Socio-economic background of wastewater irrigation and bioaccumulation of heavy metals in crops and vegetables. Agr Water Manage. 158:26–34. doi: 10.1016/j.agwat.2015.04.004.
  • Rana S, Bag S, Golder D, Roy SM, Pradhan C, Jana B. 2011. Reclamation of municipal domestic wastewater by aquaponics of tomato plants. Ecol Eng. 37(6):981–988. doi: 10.1016/j.ecoleng.2011.01.009.
  • Randhawa M, Ahmad G, Anjum F, Asghar A, Sajid M. 2014. Heavy metal contents and their daily intake in vegetables under peri-urban farming system of Multan, Pakistan. Pak J Agric Sci. 51(4):36–42.
  • Rani KU, Sharma K, Nagasri K, Chandrika D, Savithri V, Lal M. 2014. Effect of long-term sewage water irrigation on micronutrient and heavy metal content in soil and plants under musi river basin in hyderabad. J Ind Pollut Control. 30(1):56–61.
  • Ranjbar G, Kariminejad F, Jamali J, Shams M, Najafpoor AA, Dehghan A. 2022. Heavy metal concentration in water, soil and cultivated vegetables at the edge of Kashaf Roud River, Mashhad, Iran: ecological risk assessment and bioaccumulation factor. Int J Environ Anal Chem. Chemistry.1–22. doi: 10.1080/03067319.2022.2089031.
  • Rattan R, Datta S, Chhonkar P, Suribabu K, Singh A. 2005. Long-term impact of irrigation with sewage effluents on heavy metal content in soils, crops and groundwater—a case study. Agric Ecosyst Environ. 109(3–4):310–322. doi: 10.1016/j.agee.2005.02.025.
  • Rehman K, Ashraf S, Rashid U, Ibrahim M, Hina S, Iftikhar T, Ramzan S. 2013. Comparison of proximate and heavy metal contents of vegetables grown with fresh and wastewater. Pak J Bot. 45(2):391–400.
  • Rehman A, Bhatti HN, Athar H-U-R. 2008. Textile effluents affected seed germination and early growth of some Winter vegetable crops: a case study. Water Air Soil Pollut. 198(1–4):155–163. doi: 10.1007/s11270-008-9834-5.
  • Rehman A, Bhatti HN, H-U-R A. 2009. Textile effluents affected seed germination and early growth of some winter vegetable crops: a case study. Water Air Soil Pollut. 198(1–4):155–163. doi: 10.1007/s11270-008-9834-5.
  • Rehman ZU, Khan S, Brusseau ML, Shah MT. 2017. Lead and cadmium contamination and exposure risk assessment via consumption of vegetables grown in agricultural soils of five-selected regions of Pakistan. Chemosphere. 168:1589–1596. doi: 10.1016/j.chemosphere.2016.11.152.
  • Rizzo L, Fiorentino A, Grassi M, Attanasio D, Guida M. 2015. Advanced treatment of urban wastewater by sand filtration and graphene adsorption for wastewater reuse: effect on a mixture of pharmaceuticals and toxicity. J Environ Chem Eng. 3(1):122–128. doi: 10.1016/j.jece.2014.11.011.
  • Romaniuk AM, Lyndin MS, Moskalenko RA, Hortynska OM, Lyndina YM. 2016. The role of heavy metal salts in pathological biomineralization of breast cancer tissue. Advances In Clinical And Experimental Medicine. 25(5):907–910. doi: 10.17219/acem/34472.
  • Roschzttardtz H, Conéjéro G, Divol F, Alcon C, Verdeil J-L, Curie C, Mari S. 2013. New insights into Fe localization in plant tissues. Front Plant Sci. 4:350. doi: 10.3389/fpls.2013.00350.
  • Sadiq Butt M, Sharif K, Ehsan Bajwa B, Aziz A. 2005. Hazardous effects of sewage water on the environment: focus on heavy metals and chemical composition of soil and vegetables. Manag Environ Qual: Int J. 16(4):338–346. doi: 10.1108/14777830510601217.
  • Safi Z, Buerkert A. 2011. Heavy metal and microbial loads in sewage irrigated vegetables of Kabul, Afghanistan. Journal Of Agriculture And Rural Development In The Tropics And Subtropics (JARTS). 112(1):29–36.
  • Sahni P, Sharma S. 2023. Quality characteristics, amino acid composition, and bioactive potential of wheat cookies protein-enriched with unconventional legume protein isolates. Qual Assur Saf Crops Foods. 15(2):1–10. doi: 10.15586/qas.v15i2.1160.
  • Sahu R, Katiyar S, Tiwari J, Kisku G. 2007. Assessment of drain water receiving effluent from tanneries and its impact on soil and plants with particular emphasis on bioaccumulation of heavy metals. J Environ Biol. 28(3):685.
  • Samaila B, Aisha I, Shehu A, Bako A. 2021. Evaluation of chronic daily intake, pollution index and incremental life cancer risk to adults due to exposures to heavy metals in surface and ground water. Evaluation. 9(6):72–80.
  • Sandeep G, Vijayalatha K, Anitha T. 2019. Heavy metals and its impact in vegetable crops. Int J Chem Stud. 7(1):1612–1621.
  • Santos RS, Sanches FA, Leitão RG, Leitão CC, Oliveira DF, Anjos MJ, Assis JT. 2019. Multielemental analysis in Nerium Oleander L. leaves as a way of assessing the levels of urban air pollution by heavy metals. Appl Radiat Isot. 152:18–24. doi: 10.1016/j.apradiso.2019.06.020.
  • Sarkar T, Mukherjee A, Chatterjee K, Smaoui S, Pati S, Shariati MA. 2023. Progressive quality estimation of oyster mushrooms using neural network–based image analysis. Qual Assur Saf Crops Foods. 15(SP1):16–26. doi: 10.15586/qas.v15iSP1.1272.
  • Sayo S, Kiratu JM, Nyamato GS. 2020. Heavy metal concentrations in soil and vegetables irrigated with sewage effluent: a case study of Embu sewage treatment plant, Kenya. Afr J Biol Sci. 8:e00337. doi: 10.1016/j.sciaf.2020.e00337.
  • Shah FUR, Ahmad N, Masood KR, Peralta-Videa JR. 2010. Heavy metal toxicity in plants. Plant adaptation and phytoremediation. New York City: Springer; pp. 71–97.
  • Shaheen N, Irfan NM, Khan IN, Islam S, Islam MS, Ahmed MK. 2016. Presence of heavy metals in fruits and vegetables: health risk implications in Bangladesh. Chemosphere. 152:431–438. doi: 10.1016/j.chemosphere.2016.02.060.
  • Shahid M, Dumat C, Khalid S, Schreck E, Xiong T, Niazi NK. 2017. Foliar heavy metal uptake, toxicity and detoxification in plants: a comparison of foliar and root metal uptake. J Hazard Mater. 325:36–58. doi: 10.1016/j.jhazmat.2016.11.063.
  • Shariatpanahi M, Anderson AC. 1986. Accumulation of cadmium, mercury and lead by vegetables following long-term land application of wastewater. Sci Total Environ. 52(1–2):41–47. doi: 10.1016/0048-9697(86)90103-8.
  • Sharma R, Agrawal M, Marshall F. 2006. Heavy metal contamination in vegetables grown in wastewater irrigated areas of Varanasi, India. Bull Environ Contam Toxicol. 77(2):312–318. doi: 10.1007/s00128-006-1065-0.
  • Sharma A, Katnoria JK, Nagpal AK. 2016. Heavy metals in vegetables: screening health risks involved in cultivation along wastewater drain and irrigating with wastewater. Springerplus. 5(1):488. doi: 10.1186/s40064-016-2129-1.
  • She X, Gao Y, Shi Y. 2023. Determination of glufosinate-ammonium residue in wheat and soil by ultra-performance liquid chromatography-tandem mass spectrometry. Qual Assur Saf Crops Foods. 15(2):244–251. doi: 10.15586/qas.v15i2.1163.
  • Shen Z, Xu D, Li L, Wang J, Shi X. 2019. Ecological and health risks of heavy metal on farmland soils of mining areas around Tongling City, Anhui, China. Environ Sci Pollut Res. 26(15):15698–15709. doi: 10.1007/s11356-019-04463-0.
  • Singh A. 2021. A review of wastewater irrigation: environmental implications. Resour Conserv Recycl. 168:105454. doi: 10.1016/j.resconrec.2021.105454.
  • Singh A, Sharma RK, Agrawal M, Marshall FM. 2010. Risk assessment of heavy metal toxicity through contaminated vegetables from waste water irrigated area of Varanasi, India. Trop Ecol. 51(2):375–387.
  • Singh S, Zacharias M, Kalpana S, Mishra S. 2012. Heavy metals accumulation and distribution pattern in different vegetable crops. J Environ Chem Ecotoxicol. 4(10):170–177. doi: 10.5897/JECE11.076.
  • Sinha S, Gupta A, Bhatt K, Pandey K, Rai U, Singh K. 2006. Distribution of metals in the edible plants grown at Jajmau, Kanpur (India) receiving treated tannery wastewater: relation with physico-chemical properties of the soil. Environ Monit Assess. 115(1–3):1–22. doi: 10.1007/s10661-006-5036-z.
  • Siripongvutikorn S, Usawakesmanee W, Pisuchpen S, Khatcharin N, Rujirapong C. 2023. Quality changes during storage in Thai indigenous leafy vegetable, Liang leaves (Gnetum gnemon var. tenerum) after different preparation methods. Ital J Food Sci. 35(3):1–16. doi: 10.15586/ijfs.v35i3.2346.
  • Souri MK, Alipanahi N, Hatamian M, Ahmadi M, Tesfamariam T. 2018. Elemental profile of heavy metals in garden cress, coriander, lettuce and spinach, commonly cultivated in Kahrizak, South of Tehran-Iran. Open Agric. 3(1):32–37. doi: 10.1515/opag-2018-0004.
  • Sreekanth T, Nagajyothi P, Lee K, Prasad T. 2013. Occurrence, physiological responses and toxicity of nickel in plants. Int J Environ Sci Technol. 10(5):1129–1140. doi: 10.1007/s13762-013-0245-9.
  • Sulaivany R, Al-Mezori H. 2007. Heavy metals concentration in selected vegetables grown in Duhok City, Kurdistan region, Iraq. Wit Trans Built Env. 94:19–26.
  • Talema A. 2023. Causes, negative effects, and preventive methods of water pollution in Ethiopia. Qual Assur Saf Crops Foods. 15(2):129–139. doi: 10.15586/qas.v15i2.1271.
  • Tang Y, Yang G, Liu X, Qin L, Zhai W, Fodjo EK, Shen X, Wang Y, Lou X, Kong C. 2023. Rapid Sample Enrichment, novel derivatization, and high sensitivity for determination of 3-chloropropane-1, 2-diol in soy sauce via high-performance liquid chromatography–tandem Mass spectrometry. J Agric Food Chem. 71(41):15388–15397. doi: 10.1021/acs.jafc.3c05230.
  • Tang T, Zhou M, Lv J, Cheng H, Wang H, Qin D, Hu G, Liu X. 2022. Sensitive and selective electrochemical determination of uric acid in urine based on ultrasmall iron oxide nanoparticles decorated urchin-like nitrogen-doped carbon. Colloids Surf B. 216:112538.
  • Tariq FS. 2021. Heavy metals concentration in vegetables irrigated with municipal wastewater and their human daily intake in Erbil city. Environmental Nanotechnology, Monitoring & Management. 16:100475. doi: 10.1016/j.enmm.2021.100475.
  • Thakaew R, Chaiklangmuang S. 2023. Aflatoxin B1 elimination in low-grade maize by co-influence of heat and chemical treatment. Qual Assur Saf Crops Foods. 15(3):55–67. doi: 10.15586/qas.v15i3.1233.
  • Theodore L, Dupont RR. 2017. Environmental Health and hazard risk assessment: principles and calculations. Boca Raton, Florida: CRC Press.
  • Turan V, Khan SA, Iqbal M, Ramzani PMA, Fatima M. 2018. Promoting the productivity and quality of brinjal aligned with heavy metals immobilization in a wastewater irrigated heavy metal polluted soil with biochar and chitosan. Ecotox Environ Safe. 161:409–419. doi: 10.1016/j.ecoenv.2018.05.082.
  • Ugya A, Ahmad A, Adamu H, Giwa S, Imam T. 2019. Phytoextraction of heavy metals and risk associated with vegetables grown from soil irrigated with refinery wastewater. Journal Of Applied Biology And Biotechnology. 7(2):1–9.
  • Ullah H, Khan N, Ali F, Shah Z, Ullah Q. 2018. Health risk of heavy metals from vegetables irrigated with sewage water in peri-urban of Dera Ismail Khan, Pakistan. Int J Environ Sci Technol. 15(2):309–322. doi: 10.1007/s13762-017-1384-1.
  • Védry B, Gousailles M, Affholder M, Lefaux A, Bontoux J. 2001. From sewage water treatment to wastewater reuse. One century of Paris sewage farms history. Water Sci Technol. 43(10):101–107. doi: 10.2166/wst.2001.0592.
  • Verma P, Agrawal M, Sagar R. 2015. Assessment of potential health risks due to heavy metals through vegetable consumption in a tropical area irrigated by treated wastewater. Environ Syst Decis. 35(3):375–388. doi: 10.1007/s10669-015-9558-1.
  • Waheed H, Ilyas N, Iqbal Raja N, Mahmood T, Ali Z. 2019. Heavy metal phyto-accumulation in leafy vegetables irrigated with municipal wastewater and human health risk repercussions. Int J Phytoremediat. 21(2):170–179. doi: 10.1080/15226514.2018.1540547.
  • Wang Y, Qiao M, Liu Y, Zhu Y. 2012. Health risk assessment of heavy metals in soils and vegetables from wastewater irrigated area, Beijing-Tianjin city cluster, China. J Environ Sci. 24(4):690–698. doi: 10.1016/S1001-0742(11)60833-4.
  • Weinstein C, Moynier F, Wang K, Paniello R, Foriel J, Catalano J, Pichat S. 2011. Isotopic fractionation of Cu in plants. Chem Geol. 286(3–4):266–271. doi: 10.1016/j.chemgeo.2011.05.010.
  • Woldetsadik D, Drechsel P, Keraita B, Itanna F, Gebrekidan H. 2017. Heavy metal accumulation and health risk assessment in wastewater-irrigated urban vegetable farming sites of Addis Ababa, Ethiopia. International Journal Of Food Contamination. 4(1). doi: 10.1186/s40550-017-0053-y.
  • Wu Y, Gong W, Wang Y, Yong T, Yang F, Liu W, Wu X, Du J, Shu K, Liu J. 2018. Leaf area and photosynthesis of newly emerged trifoliolate leaves are regulated by mature leaves in soybean. J Plant Res. 131(4):671–680. doi: 10.1007/s10265-018-1027-8.
  • Xiao-Mei H, Jin Y, Chao L, Xiao-Jun F, Yuan Z. 2023. Analysis of hydrochemical characteristics and genesis of water-deficient rivers in China: a case study of the Ciyao River Basin in Shanxi Province. Qual Assur Saf Crops Foods. 15(1):32–43. doi: 10.15586/qas.v15i1.1213.
  • Xiong J, Wen D, Zhou H, Chen R, Wang H, Wang C, Wu Z, Qiu Y, Wu L. (2022). Occurrence of aflatoxin M1 in yogurt and milk in central-eastern China and the risk of exposure in milk consumers. Food Control. 137:108928. doi: 10.1016/j.foodcont.2022.108928.
  • Xue Z-J, Liu S-Q, Liu Y-L, Yan Y-L. 2012. Health risk assessment of heavy metals for edible parts of vegetables grown in sewage-irrigated soils in suburbs of Baoding City, China. Environ Monit Assess. 184(6):3503–3513. doi: 10.1007/s10661-011-2204-6.
  • Yang Q, Li Z, Lu X, Duan Q, Huang L, Bi J. 2018. A review of soil heavy metal pollution from industrial and agricultural regions in China: pollution and risk assessment. Sci Total Environ. 642:690–700. doi: 10.1016/j.scitotenv.2018.06.068.
  • Yu J, Hu W, Wu D, Ding Y, Wang X, Liu P. 2022. Determination of aspartame and alitame in liquid dairy products and milk-containing beverages in the Chinese market. Ital J Food Sci. 34(3):91–98. doi: 10.15586/ijfs.v34i3.2225.
  • Zamanpour S, Noori SMA, Yancheshmeh BS, Afshari A, Hashemi M. 2023. A systematic review to introduce the most effective postbiotic derived from probiotics for aflatoxin detoxifications. Ital J Food Sci. 35(4):31–49. doi: 10.15586/ijfs.v35i4.2369.
  • Zhang P, Dong T, Jin H, Pei D, Pervaiz T, Ren Y, Jia H, Fang J. 2022. Analysis of photosynthetic ability and related physiological traits in nodal leaves of grape. Sci Hortic (Amsterdam). 304:111251. doi: 10.1016/j.scienta.2022.111251.
  • Zhang L, Yang Z, Peng M, Cheng X. 2022. Contamination levels and the Ecological and Human Health Risks of Potentially Toxic Elements (PTEs) in soil of Baoshan Area, Southwest China. Appl Sci. 12(3):1693. doi: 10.3390/app12031693.
  • Zhang Y, Zhang JH, Tian Q, Liu ZH, Zhang HL. 2018. Virtual water trade of agricultural products: a new perspective to explore the belt and road. Sci Total Environ. 622-623:988–996. doi: 10.1016/j.scitotenv.2017.11.351.
  • Zhao JY, Jin XL, Shen ZL, Guo HM. 2011. Accumulation and risk assessment of heavy metals in vegetables in wastewater irrigation areas. Advanced Materials Research. 183:527–531. doi: 10.4028/www.scientific.net/AMR.183-185.527.
  • Zheng X, Zhang Z, Chen J, Liang H, Chen X, Qin Y, Shohag M, Wei Y, Gu M. 2022. Comparative evaluation of in vivo relative bioavailability and in vitro bioaccessibility of arsenic in leafy vegetables and its implication in human exposure assessment. J Hazard Mater. 423:126909.
  • Zheng Y, Zhang Z, Tang P, Wu Y, Zhang A, Li D, Wang C-Z, Wan J-Y, Yao H, Yuan C-S. 2023. Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials. Front Immunol. 14:1143548. doi: 10.3389/fimmu.2023.1143548.
  • Zhou H, Yang W-T, Zhou X, Liu L, Gu J-F, Wang W-L, Zou J-L, Tian T, Peng P-Q, Liao B-H. 2016. Accumulation of heavy metals in vegetable species planted in contaminated soils and the health risk assessment. Int J Envir Res Pub Health. 13(3):289. doi: 10.3390/ijerph13030289.
  • Zhu J, Cai J, Sun B, Xu Y, Lu F, Ma H. 2023. Inspection and classification of wheat quality using image processing. Qual Assur Saf Crops Foods. 15(3):43–54. doi: 10.15586/qas.v15i3.1220.
  • Zhu J, Fan S, He M, Wang N, Xu X, Pang J, Yan Y, Li L, Yang J, Chang W-T. 2023. Quality-grade analysis of velvet antler materials using ultra-weak delayed luminescence combined with chemometrics. Qual Assur Saf Crops Foods. 15(4):1–10. doi: 10.15586/qas.v15i4.1311.
  • Zoghi A, Salimi M, Mirmahdi RS, Massoud R, Khosravi-Darani K, Mohammadi R, Rouhi M, Tripathy AD. 2022. Effect of pretreatments on bioremoval of metals and subsequent exposure to simulated gastrointestinal conditions. Qual Assur Saf Crops Foods. 14(3):145–155. doi: 10.15586/qas.v14i3.1012.
  • Zwolak A, Sarzyńska M, Szpyrka E, Stawarczyk K. 2019. Sources of soil pollution by heavy metals and their accumulation in vegetables: a review. Water Air Soil Pollut. 230(7):1–9. doi: 10.1007/s11270-019-4221-y.

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