Publication Cover
Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 26, 2023 - Issue 11
433
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Effects of anti-Inflammatory-antioxidant-rich diet and co-supplemented synbiotics intervention in patients with progressive forms of multiple sclerosis: a single-center, single-blind randomized clinical trial

ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon

References

  • Moravejolahkami AR, Paknahad Z, Chitsaz A. Dietary intake of energy and fiber in MS patients; an approach to prebiotics role. Nutr Food Sci. 2019;49(6):1039–50.
  • Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, et al. Spinal cord atrophy predicts progressive disease in relapsing multiple sclerosis. Ann Neurol. 2022;91(2):268–81.
  • Kalincik T, Diouf I, Sharmin S, Malpas C, Spelman T, Horakova D, et al. Effect of disease-modifying therapy on disability in relapsing-remitting multiple sclerosis over 15 years. Neurology. 2021;96(5):e783–e97.
  • Lange L, Shiner M. Small-bowel abnormalities in multiple sclerosis. The Lancet. 1976;308(7999):1319–22.
  • Cantoni C, Lin Q, Dorsett Y, Ghezzi L, Liu Z, Pan Y, et al. Alterations of host-gut microbiome interactions in multiple sclerosis. eBioMedicine. 2022;76:103798.
  • Liébana-García R, Olivares M, Bullich-Vilarrubias C, López-Almela I, Romaní-Pérez M, Sanz Y. The gut microbiota as a versatile immunomodulator in obesity and associated metabolic disorders. Best Pract Res Clin Endocrinol Metab. 2021;35(3):101542.
  • Riccio P, Rossano R. Nutrition facts in multiple sclerosis. ASN Neuro. 2015;7(1):1759091414568185.
  • Moravejolahkami A, Chitsaz A. Mediterranean-style diet Co-supplemented with synbiotics improved quality of life, fatigue and disease activity in five secondary progressive multiple sclerosis patients. Ann Med Surg Case Rep: AMSCR. 2019;02:1–3.
  • Askari G, Ghavami A, Shahdadian F, Moravejolahkami AR. Effect of synbiotics and probiotics supplementation on autoimmune diseases: A systematic review and meta-analysis of clinical trials. Clin Nutr. 2021;40(5):3221–34.
  • Kouchaki E, Tamtaji OR, Salami M, Bahmani F, Kakhaki RD, Akbari E, et al. Clinical and metabolic response to probiotic supplementation in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled trial. Clin Nutr. 2017;36(5):1245–9.
  • Salami M, Kouchaki E, Asemi Z, Tamtaji OR. How probiotic bacteria influence the motor and mental behaviors as well as immunological and oxidative biomarkers in multiple sclerosis? A double blind clinical trial. J Funct Foods. 2019;52:8–13.
  • Tamtaji OR, Kouchaki E, Salami M, Aghadavod E, Akbari E, Tajabadi-Ebrahimi M, et al. The effects of probiotic supplementation on gene expression related to inflammation, insulin, and lipids in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled trial. J Amer Coll Nutr. 2017;36(8):660–5.
  • Rahimlou M, Hosseini SA, Majdinasab N, Haghighizadeh MH, Husain D. Effects of long-term administration of Multi-Strain Probiotic on circulating levels of BDNF, NGF, IL-6 and mental health in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled trial. Nutr Neurosci. 2022;25(2):411–22.
  • Bohlouli J, Namjoo I, Borzoo-Isfahani M, Kermani MAH, Zehi ZB, Moravejolahkami AR. Effect of probiotics on oxidative stress and inflammatory status in diabetic nephropathy: A systematic review and meta-analysis of clinical trials. Heliyon. 2021;7(1):e05925.
  • Riccio P, Rossano R. Diet, gut microbiota, and vitamins D+ A in multiple sclerosis. Neurotherapeutics. 2018;15(1):75–91.
  • Holton KF, Kirkland AE. Moving past antioxidant supplementation for the dietary treatment of multiple sclerosis. Mult Scler J. 2020;26(9):1012–23.
  • Padureanu R, Albu CV, Mititelu RR, Bacanoiu MV, Docea AO, Calina D, et al. Oxidative stress and inflammation interdependence in multiple sclerosis. J Clin Med. 2019;8(11):1815.
  • Haytowitz DB, Bhagwat S. USDA database for the oxygen radical absorbance capacity (ORAC) of selected foods, release 2. US Dep Agricult. 2010;3(1):10–48.
  • Bohlouli J, Namjoo I, Borzoo-Isfahani M, Poorbaferani F, Moravejolahkami AR, Clark CC, et al. Modified Mediterranean diet v. traditional Iranian diet: efficacy of dietary interventions on dietary inflammatory index score, fatigue severity and disability in multiple sclerosis patients. Brit J Nutr. 2021;1:1–11.
  • Jukic A, Bakiri L, Wagner EF, Tilg H, Adolph TE. Calprotectin: from biomarker to biological function. Gut. 2021;70(10):1978–88.
  • Shozan A, Mohammad E. Value of cerebrospinal fluid calprotectin assay in patients with acute meningitis. Med J Cairo Univ. 2022;90(3):185–93.
  • Olsson A, Gustavsen S, Langkilde A, Hansen T, Sellebjerg F, Søndergaard HB, et al. Circulating levels of tight junction proteins in multiple sclerosis: association with inflammation and disease activity before and after disease modifying therapy. Mult Scler Rel Disord. 2021;54:103136.
  • Mousavi-Shirazi-Fard Z, Mazloom Z, Izadi S, Fararouei M. The effects of modified anti-inflammatory diet on fatigue, quality of life, and inflammatory biomarkers in relapsing-remitting multiple sclerosis patients: a randomized clinical trial. Intern J Neurosci. 2021;131(7):657–65.
  • Kurtzke JF. Rating neurologic impairment in multiple sclerosis an expanded disability status scale (EDSS). Neurology. 1983;33(11):1444.
  • Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol. 2011;69(2):292–302.
  • Association GAotWM. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J Amer Coll Dentists. 2014;81(3):14.
  • Riccio P, Rossano R, Larocca M, Trotta V, Mennella I, Vitaglione P, et al. Anti-inflammatory nutritional intervention in patients with relapsing-remitting and primary-progressive multiple sclerosis: A pilot study. Exper Biol Med. 2016;241(6):620–35.
  • Alfawaz HA, Bhat RS, Arzoo S, Soliman DA, Hassan SA, El-Ansary A. Comparative study on the exacerbating effects of casein-rich vs. gluten-rich diets on biochemical-induced features in rodent model of autism. J Mol Neurosci. 2022;72(2):359–71.
  • Shivappa N, Steck SE, Hurley TG, Hussey JR, Ma Y, Ockene IS, et al. A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS). Public Health Nutr. 2014;17(8):1825–33.
  • Marakis TP, Koutsandrea C, Poulou MS. The impact of vision impairment on vision-related quality of life of patients with neovascular age-related macular degeneration. Eur J Ophthalmol. 2022;32(1):481–90.
  • Finger RP, Fenwick E, Marella M, Dirani M, Holz FG, Chiang PP-C, et al. The impact of vision impairment on vision-specific quality of life in Germany. Invest Ophthalmol Visual Sci. 2011;52(6):3613–9.
  • Bulbuloglu S, Gunes H, Saritas S. The effect of long-term immunosuppressive therapy on gastrointestinal symptoms after kidney transplantation. Transplant Immunol. 2022;70:101515.
  • Akbari Namvar Z, Mahdavi R, Shirmohammadi M, Nikniaz Z. The effect of group-based education on gastrointestinal symptoms and quality of life in patients with celiac disease: randomized controlled clinical trial. BMC Gastroenterol. 2022;22(1):1–7.
  • Heymsfield SB, McManus C, Smith J, Stevens V, Nixon DW. Anthropometric measurement of muscle mass: revised equations for calculating bone-free arm muscle area. Amer J Clin Nutr. 1982;36(4):680–90.
  • Visser M, Van Den Heuvel E, Deurenberg P. Prediction equations for the estimation of body composition in the elderly using anthropometric data. Brit J Nutr. 1994;71(6):823–33.
  • Martel J, Chang S-H, Ko Y-F, Hwang T-L, Young JD, Ojcius DM. Gut barrier disruption and chronic disease. Trends Endocrinol Metab. 2022;33(4):247–265.
  • Camara-Lemarroy CR, Silva C, Greenfield J, Liu W-Q, Metz LM, Yong VW. Biomarkers of intestinal barrier function in multiple sclerosis are associated with disease activity. Mult Scler J. 2020;26(11):1340–50.
  • Ponziani FR, De Luca A, Picca A, Marzetti E, Petito V, Del Chierico F, et al. Gut dysbiosis and fecal calprotectin predict response to immune checkpoint inhibitors in patients with hepatocellular carcinoma. Hepatol Commun. 2022.
  • Kooshki A, Tofighiyan T, Miri M. A synbiotic supplement for inflammation and oxidative stress and lipid abnormalities in hemodialysis patients. Hemodialysis Intern. 2019;23(2):254–60.
  • Li W, Huang W, Ma Y, Muhammad I, Hanif A, Ding Z, et al. Antioxidant properties of lactic acid bacteria isolated from traditional fermented yak milk and their probiotic effects on the oxidative senescence of Caenorhabditis elegans. Food Function. 2022;13(6):3690–703.
  • Zhu J, Ling Y, Mi S, Chen H, Fan J, Cai S, et al. Association between dietary inflammatory index and upper aerodigestive tract cancer risk: A systematic review and dose-response meta-analysis. Oral Oncol. 2020;103:104587.
  • Kizil M, Tengilimoglu-Metin MM, Gumus D, Sevim S, Turkoglu İ, Mandiroglu F. Dietary inflammatory index is associated with serum C-reactive protein and protein energy wasting in hemodialysis patients: A cross-sectional study. Nutr Res Pract. 2016;10(4):404–10.
  • Batar N, Öztürk ES, Sevdin S, Yıldız N. Relationship between weight loss and dietary inflammatory index and serum C-reactive protein level before and after bariatric surgery. Bariat Surg Pract Patient Care. 2022.
  • Moravejolahkami AR, Paknahad Z, Chitsaz A, Hojjati Kermani MA, Borzoo-Isfahani M. Potential of modified Mediterranean diet to improve quality of life and fatigue severity in multiple sclerosis patients: a single-center randomized controlled trial. Intern J Food Proper. 2020;23(1):1993–2004.
  • Moravejolahkami AR, Paknahad Z, Chitsaz A. Association of dietary patterns with systemic inflammation, quality of life, disease severity, relapse rate, severity of fatigue and anthropometric measurements in MS patients. Nutr Neurosc. 2019: 1–11.
  • Mirashrafi S, Borzoo-Isfahani M, Namjoo I, Hojjati Kermani MA, Moravejolahkami AR. A Mediterranean-type diet improved systemic inflammation in multiple sclerosis patients, as compared to the traditional Iranian diet: A single-center randomized controlled trial. Mediterr J Nutr Metab. 2021;14(3):289–304.
  • Mirashrafi S, Hejazi Taghanaki SZ, Sarlak F, Moravejolahkami AR, Hojjati Kermani MA, Haratian M. Effect of probiotics supplementation on disease progression, depression, general health, and anthropometric measurements in relapsing-remitting multiple sclerosis patients: A systematic review and meta-analysis of clinical trials. Intern J Clin Pract. 2021;75(11):e14724.
  • Hoff JM, Dhayalan M, Midelfart A, Tharaldsen AR, Bø L. Visual dysfunction in multiple sclerosis. Tidsskrift for Den norske legeforening; 2019.
  • Askari G, Moravejolahkami AR. Synbiotic supplementation may relieve anterior uveitis, an ocular manifestation in behcet’s syndrome. Amer J Case Rep. 2019;20:548.
  • Moravejolahkami AR, Hojjati Kermani MA, Balouch Zehi Z, Mirenayat SMS, Mansourian M. The effect of probiotics on lipid profile & anthropometric indices in diabetic nephropathy; a systematic review and meta-analysis of clinical trials. J Diab Metab Disord. 2021;20(1):893–904.
  • Cox LM, Maghzi AH, Liu S, Tankou SK, Dhang FH, Willocq V, et al. Gut microbiome in progressive multiple sclerosis. Ann Neurol. 2021;89(6):1195–211.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.