737
Views
5
CrossRef citations to date
0
Altmetric
Reviews

An update on the effects of food-derived active peptides on the intestinal microecology

ORCID Icon, ORCID Icon & ORCID Icon
Pages 11625-11639 | Published online: 06 Jul 2022

References

  • Ahlawat, S., Asha, and K. K. Sharma. 2020. Immunological co-ordination between gut and lungs in SARS-CoV-2 infection. Virus Research 286:198103. doi: 10.1016/j.virusres.2020.198103.
  • Aktas, B., and B. Aslim. 2020. Gut-lung axis and dysbiosis in COVID-19. Turkish Journal of Biology  44 (3):265–72. doi: 10.3906/biy-2005-102.
  • Apostolopoulos, V., J. Bojarska, T. T. Chai, S. Elnagdy, K. Kaczmarek, J. Matsoukas, R. New, K. Parang, O. P. Lopez, H. Parhiz, et al. 2021. A global review on short peptides: Frontiers and perspectives. Molecules 26 (2):430. doi: 10.3390/molecules26020430.
  • Aslam, H., A. Ruusunen, M. Berk, A. Loughman, L. Rivera, J. A. Pasco, and F. N. Jacka. 2020. Unravelled facets of milk derived opioid peptides: A focus on gut physiology, fractures and obesity. International Journal of Food Sciences and Nutrition 71 (1):36–49. doi: 10.1080/09637486.2019.1614540.
  • Bacci, G., A. Rossi, F. Armanini, L. Cangioli, I. De Fino, N. Segata, A. Mengoni, A. Bragonzi, and A. Bevivino. 2021. Lung and gut microbiota changes associated with pseudomonas aeruginosa infection in mouse models of cystic fibrosis. International Journal of Molecular Sciences 22 (22):12169. doi: 10.3390/ijms222212169.
  • Bagchi, D., G. Bhattacharya, and S. J. Stohs. 1996. Production of reactive oxygen species by gastric cells in association with Helicobacter pylori. Free Radical Research 24 (6):439–50. doi: 10.3109/10715769609088043.
  • Bin, P., M. A. K. Azad, G. Liu, D. Zhu, S. W. Kim, and Y. Yin. 2018. Effects of different levels of methionine on sow health and plasma metabolomics during late gestation. Food & Function 9 (9):4979–88. doi: 10.1039/C8FO01477A.
  • Cai, X., Y. Han, M. Gu, M. Song, X. Wu, Z. Li, F. Li, T. Goulette, and H. Xiao. 2019. Dietary cranberry suppressed colonic inflammation and alleviated gut microbiota dysbiosis in dextran sodium sulfate-treated mice. Food & Function 10 (10):6331–41. doi: 10.1039/C9FO01537J.
  • Chakrabarti, S., S. Guha, and K. Majumder. 2018. Food-derived bioactive peptides in human health: Challenges and opportunities. Nutrients 10 (11):1738. doi: 10.3390/nu10111738.
  • Chalamaiah, M., W. Yu, and J. Wu. 2018. Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins: A review. Food Chemistry 245:205–22. doi: 10.1016/j.foodchem.2017.10.087.
  • Cheng, S., M. Tu, H. Liu, G. Zhao, and M. Du. 2019. Food-derived antithrombotic peptides: Preparation, identification, and interactions with thrombin. Critical Reviews in Food Science and Nutrition 59 (sup1):S81–S95. doi: 10.1080/10408398.2018.1524363.
  • Choi, W., J. Namkung, I. Hwang, H. Kim, A. Lim, H. J. Park, H. W. Lee, K.-H. Han, S. Park, J.-S. Jeong, et al. 2018. Serotonin signals through a gut-liver axis to regulate hepatic steatosis. Nature Communications 9 (1):4824. doi: 10.1038/s41467-018-07287-7.
  • Chovatiya, R., and R. Medzhitov. 2014. Stress, inflammation, and defense of homeostasis. Molecular Cell 54 (2):281–8. doi: 10.1016/j.molcel.2014.03.030.
  • Chu, F., X. Jin, and H. Ma. 2019. Anti-diarrhea effects and identification of Musca domestica larvae low molecular weight peptides (LMWP). Journal of Pharmaceutical and Biomedical Analysis 173:162–8. doi: 10.1016/j.jpba.2019.05.032.
  • Clemens, R. A. 2011. Milk A1 and A2 peptides and diabetes. Nestle Nutrition Institute Workshop Series, Pediatric Programme 67:187–95. doi: 10.1159/000325584.
  • Daliri, E. B., C. N. Tango, B. H. Lee, and D. H. Oh. 2018. Human microbiome restoration and safety. International Journal of Medical Microbiology: IJMM 308 (5):487–97. doi: 10.1016/j.ijmm.2018.05.002.
  • Davenport, E. R., J. G. Sanders, S. J. Song, K. R. Amato, A. G. Clark, and R. Knight. 2017. The human microbiome in evolution. BMC Biology 15 (1):127. doi: 10.1186/s12915-017-0454-7.
  • De Luis Román, D., E. Domínguez Medina, B. Molina Baena, and P. Matía-Martín. 2021. Oligomeric formulas in surgery: A Delphi and consensus study. Nutrients 13 (6):1922. doi: 10.3390/nu13061922.
  • de Oliveira, G. L. V., C. N. S. Oliveira, C. F. Pinzan, L. V. V. de Salis, and C. R. B. Cardoso. 2021. Microbiota modulation of the gut-lung axis in COVID-19. Frontiers in Immunology 12:635471. doi: 10.3389/fimmu.2021.635471.
  • Fu, C., G. Guan, and H. Wang. 2018. The anticancer effect of sanguinarine: A review. Current Pharmaceutical Design 24 (24):2760–4. doi: 10.2174/1381612824666180829100601.
  • Gadaleta, R. M., K. J. van Erpecum, B. Oldenburg, E. C. L. Willemsen, W. Renooij, S. Murzilli, L. W. J. Klomp, P. D. Siersema, M. E. I. Schipper, S. Danese, et al. 2011. Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease. Gut 60 (4):463–72. doi: 10.1136/gut.2010.212159.
  • Ganguly, A., K. Sharma, and K. Majumder. 2019. Food-derived bioactive peptides and their role in ameliorating hypertension and associated cardiovascular diseases. Advances in Food and Nutrition Research 89:165–207. doi: 10.1016/bs.afnr.2019.04.001.
  • Gupta, S., I. Singh, A. K. Sharma, and P. Kumar. 2020. Ultrashort peptide self-assembly: front-runners to transport drug and gene cargos. Frontiers in Bioengineering and Biotechnology 8:504. doi: 10.3389/fbioe.2020.00504. eCollection 2020
  • Ge, H., Z. Cai, J. Chai, J. Liu, B. Liu, Y. Yu, J. Liu, and T. Zhang. 2021. Egg white peptides ameliorate dextran sulfate sodium-induced acute colitis symptoms by inhibiting the production of pro-inflammatory cytokines and modulation of gut microbiota composition. Food Chemistry 360:129981. doi: 10.1016/j.foodchem.2021.129981.
  • Guo, D., W. Liu, X. Zhang, M. Zhao, B. Zhu, T. Hou, and H. He. 2019. Duck egg white-derived peptide VSEE (Val-Ser-Glu-Glu) regulates bone and lipid metabolisms by Wnt/β-catenin signaling pathway and intestinal microbiota. Molecular Nutrition & Food Research 63 (24):e1900525. doi: 10.1002/mnfr.201900525.
  • Hakimian, J. K., T. S. Dong, J. A. Barahona, V. Lagishetty, S. Tiwari, D. Azani, M. Barrera, S. Lee, A. L. Severino, N. Mittal, et al. 2019. Dietary supplementation with omega-3 polyunsaturated fatty acids reduces opioid-seeking behaviors and alters the gut microbiome. Nutrients 11 (8):1900. doi: 10.3390/nu11081900.
  • Han, J., X. Wang, S. Tang, C. Lu, H. Wan, J. Zhou, Y. Li, T. Ming, Z. J. Wang, and X. Su. 2020. Protective effects of tuna meat oligopeptides (TMOP) supplementation on hyperuricemia and associated renal inflammation mediated by gut microbiota. FASEB Journal 34 (4):5061–76. doi: 10.1096/fj.201902597RR.
  • Hand, T. W., I. Vujkovic-Cvijin, V. K. Ridaura, and Y. Belkaid. 2016. Linking the microbiota, chronic disease, and the immune system. Trends in Endocrinology and Metabolism: TEM 27 (12):831–43. doi: 10.1016/j.tem.2016.08.003.
  • Hayes, M. 2018. Food proteins and bioactive peptides: New and novel sources, characterisation strategies and applications. Foods 7 (3):38. doi: 10.3390/foods7030038.
  • He, S., Z. Zhang, H. Sun, Y. Zhu, X. Cao, Y. Ye, J. Wang, and Y. Cao. 2019. Potential effects of rapeseed peptide Maillard reaction products on aging-related disorder attenuation and gut microbiota modulation in d-galactose induced aging mice. Food & Function 10 (7):4291–303. doi: 10.1039/c9fo00791a.
  • He, Y., C. Jinno, C. Li, S. L. Johnston, H. Xue, Y. Liu, and P. Ji. 2022. Effects of a blend of essential oils, medium-chain fatty acids, and a toxin-adsorbing mineral on diarrhea and gut microbiome of weanling pigs experimentally infected with a pathogenic Escherichia coli. Journal Animal Science 100 (1):365. doi: 10.1093/jas/skab365.
  • Hidayat, M., S. Prahastuti, D. U. Riany, A. A. Soemardji, N. Suliska, A. N. Garmana, B. F. Assiddiq, and K. Hasan. 2019. Kidney therapeutic potential of peptides derived from the bromelain hydrolysis of green peas protein. Iranian Journal of Basic Medical Sciences 22:1016–25. doi: 10.22038/ijbms.2019.33945.8075.
  • Hisamatsu, T., S. Okamoto, M. Hashimoto, T. Muramatsu, A. Andou, M. Uo, M. T. Kitazume, K. Matsuoka, T. Yajima, N. Inoue, et al. 2012. Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease. PLoS One. 7 (1):e31131. doi: 10.1371/journal.pone.0031131.
  • Hong, Z., and M. Piao. 2018. Effect of quercetin monoglycosides on oxidative stress and gut microbiota diversity in mice with dextran sodium sulphate-induced colitis. BioMed Research International 2018:8343052. doi: 10.1155/2018/8343052.
  • Hou, T., N. Kolba, R. P. Glahn, and E. Tako. 2017. Intra-amniotic administration (Gallus gallus) of Cicer arietinum and lens culinaris prebiotics extracts and duck egg white peptides affects calcium status and intestinal functionality. Nutrients 9 (7):785. doi: 10.3390/nu9070785.
  • Inoue, N., K. Nagao, K. Sakata, N. Yamano, P. E. Gunawardena, S. Y. Han, T. Matsui, T. Nakamori, H. Furuta, K. Takamatsu, et al. 2011. Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo. Lipids in Health and Disease 10:85. doi: 10.1186/1476-511X-10-85.
  • Javdan, B., J. G. Lopez, P. Chankhamjon, Y.-C J. Lee, R. Hull, Q. Wu, X. Wang, S. Chatterjee, and M. S. Donia. 2020. Personalized mapping of drug metabolism by the human gut microbiome. Cell 181 (7):1661–79.e1622. doi: 10.1016/j.cell.2020.05.001.
  • Ji, Y., Y. Yin, L. Sun, and W. Zhang. 2020. The molecular and mechanistic insights based on gut-liver axis: Nutritional target for non-alcoholic fatty liver disease (NAFLD) improvement. International Journal of Molecular Sciences 21 (9):3066. doi: 10.3390/ijms21093066.
  • Jiao, H., Q. Zhang, Y. Lin, Y. Gao, and P. Zhang. 2019. The ovotransferrin-derived peptide IRW attenuates lipopolysaccharide-induced inflammatory responses. BioMed Research International 2019:1–7. doi: 10.1155/2019/8676410.
  • Jiménez, M., D. Cervantes-García, Y. H. Muñoz, A. García, L. M. Haro, and E. Salinas. 2016. Novel mechanisms underlying the therapeutic effect of glycomacropeptide on allergy: Change in gut microbiota, upregulation of TGF-β, and inhibition of mast cells. International Archives of Allergy and Immunology 171 (3–4):217–26. doi: 10.1159/000453035.
  • Kamiński, S., A. Cieslińska, and E. Kostyra. 2007. Polymorphism of bovine beta-casein and its potential effect on human health. Journal of Applied Genetics 48 (3):189–98. doi: 10.1007/BF03195213.
  • Ketnawa, S., and Y. Ogawa. 2021. In vitro protein digestibility and biochemical characteristics of soaked, boiled and fermented soybeans. Scientific Reports 11 (1):14257. doi: 10.1038/s41598-021-93451-x.
  • Kuellenberg de Gaudry, D., S. Lohner, K. Bischoff, C. Schmucker, S. Hoerrlein, C. Roeger, L. Schwingshackl, and J. J. Meerpohl. 2022. A1 and A2 beta-casein on health-related outcomes: A scoping review of animal studies. European Journal of Nutrition 61 (1):1–21. doi: 10.1007/s00394-021-02551-x.
  • Lach, G., H. Schellekens, T. G. Dinan, and J. F. Cryan. 2018. Anxiety, depression, and the microbiome: A role for gut peptides. Neurotherapeutics 15 (1):36–59. doi: 10.1007/s13311-017-0585-0.
  • Laukens, D., B. M. Brinkman, J. Raes, M. De Vos, and P. Vandenabeele. 2016. Heterogeneity of the gut microbiome in mice: Guidelines for optimizing experimental design. FEMS Microbiology Reviews 40 (1):117–32. doi: 10.1093/femsre/fuv036.
  • Lee, J. R., J. E. Muckerman, A. M. Wright, D. J. Davis, T. E. Childs, C. E. Gillespie, V. J. Vieira-Potter, F. W. Booth, A. C. Ericsson, and M. J. Will. 2017. Sex determines effect of physical activity on diet preference: Association of striatal opioids and gut microbiota composition. Behavioural Brain Research 334:16–25. doi: 10.1016/j.bbr.2017.07.018.
  • Lee, S. Y., E. Lee, Y. M. Park, and S. J. Hong. 2018. Microbiome in the gut-skin axis in atopic dermatitis. Allergy, Asthma & Immunology Research 10 (4):354–62. doi: 10.4168/aair.2018.10.4.354.
  • Liang, Q., F. Yu, X. Cui, J. Duan, Q. Wu, P. Nagarkatti, and D. Fan. 2013. Sparstolonin B suppresses lipopolysaccharide-induced inflammation in human umbilical vein endothelial cells. Archives of Pharmacal Research 36 (7):890–6. doi: 10.1007/s12272-013-0120-8.
  • Liu, X., Q. Yang, H. Li, X. Lan, M. Kan, J. Lin, J. Wang, Z. Zhang, S. Ming, Z. Li, et al. 2021. The anti-aging effect of velvet antler polypeptide is dependent on modulation of the gut microbiota and regulation of the PPARα/APOE4 pathway. Journal of Integrative Neuroscience 20 (3):573–83. doi: 10.31083/j.jin2003061.
  • Liu, Z., and C. C. Udenigwe. 2019. Role of food-derived opioid peptides in the central nervous and gastrointestinal systems. Journal of Food Biochemistry 43 (1):e12629. doi: 10.1111/jfbc.12629.
  • Lloyd-Price, J., C. Arze, A. N. Ananthakrishnan, M. Schirmer, J. Avila-Pacheco, T. W. Poon, E. Andrews, N. J. Ajami, K. S. Bonham, C. J. Brislawn, et al. 2019. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature 569 (7758):655–62. doi: 10.1038/s41586-019-1237-9.
  • Lu, M., B. Yuan, X. Yan, Z. Sun, H. S. Lillehoj, Y. Lee, C. Baldwin-Bott, and C. Li. 2021. Clostridium perfringens-induced host-pathogen transcriptional changes in the small intestine of broiler chickens. Pathogens 10 (12):1607. doi: 10.3390/pathogens10121607.
  • Ma, Y., S. Ding, G. Liu, J. Fang, W. Yan, V. Duraipandiyan, N. A. Al-Dhabi, G. A. Esmail, and H. Jiang. 2019. Egg protein transferrin-derived peptides IRW and IQW regulate Citrobacter rodentium-induced, inflammation-related microbial and metabolomic profiles. Frontiers in Microbiology 10:643. doi: 10.3389/fmicb.2019.00643.
  • Majumder, K., and J. Wu. 2011. Purification and characterisation of angiotensin I converting enzyme (ACE) inhibitory peptides derived from enzymatic hydrolysate of ovotransferrin. Food Chemistry 126 (4):1614–9. doi: 10.1016/j.foodchem.2010.12.039.
  • Mannick, E. E., L. E. Bravo, G. Zarama, J. L. Realpe, X. J. Zhang, B. Ruiz, E. T. Fontham, R. Mera, M. J. Miller, and P. Correa. 1996. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: Effect of antibiotics and antioxidants. Cancer Research 56 (14):3238–43.
  • Martín, R., S. Miquel, L. Benevides, C. Bridonneau, V. Robert, S. Hudault, F. Chain, O. Berteau, V. Azevedo, J. M. Chatel, et al. 2017. Functional characterization of novel Faecalibacterium prausnitzii strains isolated from healthy volunteers: A step forward in the use of F. prausnitzii as a next-generation probiotic. Frontiers in Microbiology 8:1226. doi: 10.3389/fmicb.2017.01226.
  • Matsuoka, K., and T. Kanai. 2015. The gut microbiota and inflammatory bowel disease. Seminars in Immunopathology 37 (1):47–55. doi: 10.1007/s00281-014-0454-4.
  • McComb, S., A. Thiriot, B. Akache, L. Krishnan, and F. Stark. 2019. Introduction to the Immune System. Methods in Molecular Biology (Clifton, N.J.) 2024:1–24. doi: 10.1007/978-1-4939-9597-4_1.
  • Möller, N. P., K. E. Scholz-Ahrens, N. Roos, and J. Schrezenmeir. 2008. Bioactive peptides and proteins from foods: Indication for health effects. European Journal of Nutrition 47 (4):171–82. doi: 10.1007/s00394-008-0710-2.
  • Monteiro, C., M. do Carmo, B. Melo, M. Alves, C. dos Santos, S. Monteiro, M. Bomfim, E. Fernandes, and V. Monteiro-Neto. 2019. In vitro antimicrobial activity and probiotic potential of Bifidobacterium and Lactobacillus against species of Clostridium. Nutrients 11 (2):448. doi: 10.3390/nu11020448.
  • Muntané, G., X. Farré, J. A. Rodríguez, C. Pegueroles, D. A. Hughes, J. P. de Magalhães, T. Gabaldón, and A. Navarro. 2018. Biological processes modulating longevity across primates: A phylogenetic genome-phenome analysis. Molecular Biology and Evolution 35 (8):1990–2004. doi: 10.1093/molbev/msy105.
  • Ohira, H., W. Tsutsui, and Y. Fujioka. 2017. Are short chain fatty acids in gut microbiota defensive players for inflammation and atherosclerosis? Journal of Atherosclerosis and Thrombosis 24 (7):660–72. doi: 10.5551/jat.RV17006.
  • Okamura, A., S. Koyanagi, A. Dilxiat, N. Kusunose, J. J. Chen, N. Matsunaga, S. Shibata, and S. Ohdo. 2014. Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1. The Journal of Biological Chemistry 289 (36):25296–305. doi: 10.1074/jbc.M114.577023.
  • O’Toole, P. W., J. R. Marchesi, and C. Hill. 2017. Next-generation probiotics: The spectrum from probiotics to live biotherapeutics. Nature Microbiology 2:17057. doi: 10.1038/nmicrobiol.2017.57.
  • Pannaraj, P. S., F. Li, C. Cerini, J. M. Bender, S. Yang, A. Rollie, H. Adisetiyo, S. Zabih, P. J. Lincez, K. Bittinger, et al. 2017. Association between breast milk bacterial communities and establishment and development of the infant gut microbiome. JAMA Pediatrics 171 (7):647–54. doi: 10.1001/jamapediatrics.2017.0378.
  • Panya, A., P. Yongpitakwattana, P. Budchart, N. Sawasdee, S. Krobthong, A. Paemanee, S. Roytrakul, S. Rattanabunyong, K. Choowongkomon, and P.-T. Yenchitsomanus. 2019. Novel bioactive peptides demonstrating anti-dengue virus activity isolated from the Asian medicinal plant Acacia Catechu. Chemical Biology & Drug Design 93 (2):100–9. doi: 10.1111/cbdd.13400.
  • Ramakrishna, C., M. Kujawski, H. Chu, L. Li, S. K. Mazmanian, and E. M. Cantin. 2019. Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis. Nature Communications 10 (1):2153. doi: 10.1038/s41467-019-09884-6.
  • Requena, T., M. Miguel, M. Garcés-Rimón, M. C. Martínez-Cuesta, R. López-Fandiño, and C. Peláez. 2017. Pepsin egg white hydrolysate modulates gut microbiota in Zucker obese rats. Food & Function 8 (1):437–43. doi: 10.1039/C6FO01571A.
  • Reyes-Pavón, D., D. Cervantes-García, L. G. Bermúdez-Humarán, L. E. Córdova-Dávalos, A. Quintanar-Stephano, M. Jiménez, and E. Salinas. 2020. Protective effect of glycomacropeptide on food allergy with gastrointestinal manifestations in a rat model through down-regulation of type 2 immune response. Nutrients 12 (10):2942. doi: 10.3390/nu12102942.
  • Rijkers, G. T., J. G. Damoiseaux, and H. Hooijkaas. 2014. Medical immunology: Two-way bridge connecting bench and bedside. Immunology Letters 162 (2 Pt B):127–33. doi: 10.1016/j.imlet.2014.10.016.
  • Romani, L., F. Fallarino, A. De Luca, C. Montagnoli, C. D’Angelo, T. Zelante, C. Vacca, F. Bistoni, M. C. Fioretti, U. Grohmann, et al. 2008. Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature 451 (7175):211–5. doi: 10.1038/nature06471.
  • Rueda-Ruzafa, L., F. Cruz, D. Cardona, A. J. Hone, G. Molina-Torres, N. Sánchez-Labraca, and P. Roman. 2020. Opioid system ­influences gut-brain axis: Dysbiosis and related alterations. Pharmacological Research 159:104928. doi: 10.1016/j.phrs.2020.104928.
  • Rutherfurd-Markwick, K. J. 2012. Food proteins as a source of bioactive peptides with diverse functions. British Journal of Nutrition 108 (S2):S149–S157. doi: 10.1017/S000711451200253X.
  • Saeedi, B. J., K. H. Liu, J. A. Owens, S. Hunter-Chang, M. C. Camacho, R. U. Eboka, B. Chandrasekharan, N. F. Baker, T. M. Darby, B. S. Robinson, et al. 2020. Gut-resident Lactobacilli activate hepatic Nrf2 and protect against oxidative liver injury. Cell Metabolism 31 (5):956–68.e5. doi: 10.1016/j.cmet.2020.03.006.
  • Salem, I., A. Ramser, N. Isham, and M. A. Ghannoum. 2018. The gut microbiome as a major regulator of the gut-skin axis. Frontiers in Microbiology 9:1459. doi: 10.3389/fmicb.2018.01459.
  • Schneeberger, M., A. Everard, A. G. Gómez-Valadés, S. Matamoros, S. Ramírez, N. M. Delzenne, R. Gomis, M. Claret, and P. D. Cani. 2015. Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice. Scientific Reports 5:16643. doi: 10.1038/srep16643.
  • Shi, Y., R. Feng, J. Mao, S. Liu, Z. Zhou, Z. Ji, S. Chen, and J. Mao. 2021. Structural characterization of peptides from Huangjiu and their regulation of hepatic steatosis and gut microbiota dysbiosis in hyperlipidemia Mice. Frontiers in Pharmacology 12:689092. doi: 10.3389/fphar.2021.689092.
  • Song, Y., H. Zhao, J. Liu, C. Fang, and R. Miao. 2016. Effects of citral on lipopolysaccharide-induced inflammation in human umbilical vein endothelial cells. Inflammation 39 (2):663–71. doi: 10.1007/s10753-015-0292-0.
  • Sun, B. W., X. C. Zhao, G. J. Wang, N. Li, and J. S. Li. 2003. Changes of biological functions of dipeptide transporter (PepT1) and hormonal regulation in severe scald rats. World Journal of Gastroenterology 9 (12):2782–5. doi: 10.3748/wjg.v9.i12.2782.
  • Sun, S., X. Xu, X. Sun, X. Zhang, X. Chen, and N. Xu. 2019. Preparation and identification of ACE inhibitory peptides from the marine macroalga Ulva intestinalis. Marine Drugs 17 (3):179. doi: 10.3390/md17030179.
  • Swidsinski, A., J. Weber, V. Loening-Baucke, L. P. Hale, and H. Lochs. 2005. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. Journal of Clinical Microbiology 43 (7):3380–9. doi: 10.1128/JCM.43.7.3380-3389.2005.
  • Ticinesi, A., A. Nouvenne, G. Chiussi, G. Castaldo, A. Guerra, and T. Meschi. 2020. Calcium oxalate nephrolithiasis and gut microbiota: Not just a gut-kidney axis. A nutritional perspective. Nutrients 12 (2):548. doi: 10.3390/nu12020548.
  • Udayappan, S., L. Manneras-Holm, A. Chaplin-Scott, C. Belzer, H. Herrema, G. M. Dallinga-Thie, S. H. Duncan, E. S. G. Stroes, A. K. Groen, H. J. Flint, et al. 2016. Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice. NPJ Biofilms and Microbiomes 2:16009. doi: 10.1038/npjbiofilms.2016.9.
  • Vascellari, S., V. Palmas, M. Melis, S. Pisanu, R. Cusano, P. Uva, D. Perra, V. Madau, M. Sarchioto, V. Oppo, et al. 2020. Gut microbiota and metabolome alterations associated with Parkinson’s disease. mSystems 5 (5):e00561–20. doi: 10.1128/mSystems.00561-20.
  • Wang, C., F. Zeng, Y. Liu, Y. Pan, J. Xu, X. Ge, H. Zheng, J. Pang, B. Liu, and Y. Huang. 2021. Coumarin-rich Grifola frondosa ethanol extract alleviate lipid metabolism disorders and modulates intestinal flora compositions of high-fat diet rats. Journal of Functional Foods 85:104649. doi: 10.1016/j.jff.2021.104649.
  • Wang, M., W. K. Amakye, L. Guo, C. Gong, Y. Zhao, M. Yao, and J. Ren. 2019. Walnut-derived peptide PW5 ameliorates cognitive impairments and alters gut microbiota in APP/PS1 transgenic mice. Molecular Nutrition & Food Research 63 (18):e1900326. doi: 10.1002/mnfr.201900326.
  • Wang, Q., Y. Wang, X. Jiang, L. Ma, Z. Li, Y. Chang, Y. Wang, and C. Xue. 2021. Amino acid profiling with chemometric analysis as a feasible tool for the discrimination of marine-derived peptide powders. Foods 10 (6):1294. doi: 10.3390/foods10061294.
  • Wang, S., X. Zeng, Q. Yang, and S. Qiao. 2016. Antimicrobial peptides as potential alternatives to antibiotics in food animal industry. International Journal of Molecular Sciences 17 (5):603. doi: 10.3390/ijms17050603.
  • Wang, Y., Y. Gao, W. Yu, Z. Jiang, J. Qu, and K. Li. 2013. Lycopene protects against LPS-induced proinflammatory cytokine cascade in HUVECs. Die Pharmazie 68 (8):681–4.
  • Wang, Z-g., X-g. Ying, P. Gao, C-l. Wang, Y-f. Wang, X-w. Yu, J. Chen, B. Wang, and H-y. Luo. 2019. Anti-inflammatory activity of a peptide from skipjack (Katsuwonus pelamis). Marine Drugs 17 (10):582. doi: 10.3390/md17100582.
  • Wynn, T. A., and K. M. Vannella. 2016. Macrophages in tissue repair, regeneration, and fibrosis. Immunity 44 (3):450–62. doi: 10.1016/j.immuni.2016.02.015.
  • Xiang, L., Z. Qiu, R. Zhao, Z. Zheng, and X. Qiao. 2021. Advancement and prospects of production, transport, functional activity and structure-activity relationship of food-derived angiotensin converting enzyme (ACE) inhibitory peptides. Critical Reviews in Food Science and Nutrition 2021:1–27. doi: 10.1080/10408398.2021.1964433.
  • Yang, T., E. M. Richards, C. J. Pepine, and M. K. Raizada. 2018. The gut microbiota and the brain-gut-kidney axis in hypertension and chronic kidney disease. Nature Reviews. Nephrology 14 (7):442–56. doi: 10.1038/s41581-018-0018-2.
  • Yu, Y., G. Wu, Y. Jiang, B. Li, C. Feng, Y. Ge, H. Le, L. Jiang, H. Liu, Y. Shi, et al. 2020. Sea cucumber peptides improved the mitochondrial capacity of mice: A potential mechanism to enhance gluconeogenesis and fat catabolism during exercise for improved antifatigue property. Oxidative Medicine and Cellular Longevity 2020:4604387. doi: 10.1155/2020/4604387.
  • Yu, Z., W. Zhao, L. Ding, Y. Wang, F. Chen, and J. Liu. 2017. Short- and long-term antihypertensive effect of egg protein-derived peptide QIGLF. Journal of the Science of Food and Agriculture 97 (2):551–5. doi: 10.1002/jsfa.7762.
  • Zaiss, M. M., R. M. Jones, G. Schett, and R. Pacifici. 2019. The gut-bone axis: How bacterial metabolites bridge the distance. The Journal of Clinical Investigation 129 (8):3018–28. doi: 10.1172/jci128521.
  • Zhao, Y., J. Fu, P. Li, N. Chen, Y. Liu, D. Liu, and Y. Guo. 2022. Effects of dietary glucose oxidase on growth performance and intestinal health of AA broilers challenged by Clostridium perfringens. Poultry Science 101 (1):101553. doi: 10.1016/j.psj.2021.101553.
  • Zhu, X., Y. Han, J. Du, R. Liu, K. Jin, and W. Yi. 2017. Microbiota-gut-brain axis and the central nervous system. Oncotarget 8 (32):53829–38. doi: 10.18632/oncotarget.17754.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.