Recent trends in aroma release and perception during food oral processing: A review

References

• Adams, N. G., and D. Smith. 1976. The selected ion flow tube (SIFT); a technique for studying ion-neutral reactions. International Journal of Mass Spectrometry and Ion Physics 21 (3–4):349–59. doi: 10.1016/0020-7381(76)80133-7.
   Web of Science ®Google Scholar
• Ahmed, L., Y. Zhang, E. Block, M. Buehl, M. J. Corr, R. A. Cormanich, et al. 2018. Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds. Proceedings of the National Academy of Sciences of the United States of America 115 (17):3950–8. doi: 10.1073/pnas.1713026115.
   Web of Science ®Google Scholar
• Albert, A., P. Varela, A. Salvador, G. Hough, and S. Fiszman. 2011. Overcoming the issues in the sensory description of hot served food with a complex texture. Application of QDA®, flash profiling and projective mapping using panels with different degrees of training. Food Quality and Preference 22 (5):463–73. doi: 10.1016/j.foodqual.2011.02.010.
   Web of Science ®Google Scholar
• Alemzadeh, K., S. B. Jones, M. Davies, and N. West. 2021. Development of a chewing robot with built-in humanoid jaws to simulate mastication to quantify robotic agents release from chewing gums compared to human participants. IEEE Transactions on Bio-Medical Engineering 68 (2):492–504. doi: 10.1109/TBME.2020.3005863.
   PubMed Web of Science ®Google Scholar
• Anderson, A. K., K. Christoff, I. Stappen, D. Panitz, D. G. Ghahremani, G. Glover, J. D. E. Gabrieli, and N. Sobel. 2003. Sobel: Dissociated neural representations of intensity and valence in human olfaction. Nature Neuroscience 6 (2):196–202. doi: 10.1038/nn1001.
   PubMed Web of Science ®Google Scholar
• Antúnez, L., L. Vidal, L. Saldamando, A. Giménez, and G. Ares. 2017. Comparison of consumer-based methodologies for sensory characterization: Case study with four sample sets of powdered drinks. Food Quality and Preference 56:149–63. doi: 10.1016/j.foodqual.2016.09.013.
   Web of Science ®Google Scholar
• Ares, G., L. Antúnez, L. de Saldamando, and A. Giménez. 2018. Polarized sensory positioning. In Descriptive analysis in sensory evaluation, edited by S. Kemp, J. Hort, and T. Hollowood, 561–77. Hoboken, NJ, USA: John Wiley & Sons, Ltd.
   Google Scholar
• Ares, G., S. R. Jaeger, L. Antúnez, L. Vidal, A. Giménez, B. Coste, A. Picallo, and J. C. Castura. 2015. Comparison of TCATA and TDS for dynamic sensory characterization of food products. Food Research International (Ottawa, ON) 78:148–58. doi: 10.1016/j.foodres.2015.10.023.
   PubMed Web of Science ®Google Scholar
• Bayarri, S., A. J. Taylor, and J. Hort. 2006. The role of fat in flavor perception: Effect of partition and viscosity in model emulsions. Journal of Agricultural and Food Chemistry 54 (23):8862–8. doi: 10.1021/jf061537k.
   PubMed Web of Science ®Google Scholar
• Benjamin, O., P. Silcock, M. Leus, and D. W. Everett. 2012. Multilayer emulsions as delivery systems for controlled release of volatile compounds using pH and salt triggers. Food Hydrocolloids 27 (1):109–18. doi: 10.1016/j.foodhyd.2011.08.008.
   Web of Science ®Google Scholar
• Berger, M., M. Pillei, A. Mehrle, W. Recheis, F. Kral, M. Kraxner, Z. Bardosi, and W. Freysinger. 2021. Nasal cavity airflow: Comparing laser doppler anemometry and computational fluid dynamic simulations. Respiratory Physiology & Neurobiology 283:103533. doi: 10.1016/j.resp.2020.103533.
   PubMed Web of Science ®Google Scholar
• Blankenship, M. L., M. Grigorova, D. B. Katz, and J. X. Maier. 2019. Retronasal odor perception requires taste cortex, but orthonasal does not. Current Biology: CB 29 (1):62–9.e3. doi: 10.1016/j.cub.2018.11.011.
   PubMed Web of Science ®Google Scholar
• Bozza, T., J. P. Mcgann, P. Mombaerts, and M. Wachowiak. 2004. In vivo imaging of neuronal activity by targeted expression of a genetically encoded probe in the mouse. Neuron 42 (1):9–21. doi: 10.1016/S0896-6273(04)00144-8.
   PubMed Web of Science ®Google Scholar
• Brann, D. H., T. Tsukahara, C. Weinreb, M. Lipovsek, K. Van den Berge, B. Gong, R. Chance, I. C. Macaulay, H.-J. Chou, R. B. Fletcher, et al. 2020. Non-neuronal expression of SARS-COV-2 entry genes in the olfaory system suggests mechanisms underlying covid-19-associated anosmia. Science Advances 6 (31):eabc5801. doi: 10.1126/sciadv.abc5801.
   PubMed Web of Science ®Google Scholar
• Briand, L., C. Eloit, C. Nespoulous, V. Bézirard, J.-C. Huet, C. Henry, F. Blon, D. Trotier, and J.-C. Pernollet. 2002. Evidence of an odorant-binding protein in the human olfactory mucus: Location, structural characterization, and odorant-binding properties. Biochemistry, 41 (23):7241–52. doi: 10.1021/bi015916c.
   PubMed Web of Science ®Google Scholar
• Bonneau, A., R. Boulanger, M. Lebrun, I. Maraval, J. Valette, É. Guichard, and Z. Gunata. 2018. Impact of fruit texture on the release and perception of aroma compounds during in vivo consumption using fresh and processed mango fruits. Food Chemistry 239:806–15. doi: 10.1016/j.foodchem.2017.07.017.
   PubMed Web of Science ®Google Scholar
• Brüning, J., T. Hildebrandt, W. Heppt, N. Schmidt, H. Lamecker, A. Szengel, N. Amiridze, H. Ramm, M. Bindernagel, S. Zachow, et al. 2020. Characterization of the airflow within an average geometry of the healthy human nasal cavity. Scientific Reports 10 (1):3755. doi: 10.1038/s41598-020-60755-3.
   PubMed Web of Science ®Google Scholar
• Buettner, A. 2002. Influence of human salivary enzymes on odorant concentration changes occurring in vivo. 1. Esters and thiols. Journal of Agricultural and Food Chemistry 50 (11):3283–9. doi: 10.1021/jf011586r.
   PubMed Web of Science ®Google Scholar
• Buettner, A., and F. Welle. 2004. Intra-oral detection of potent odorants using a modified stir-bar sorptive extraction system in combination with HRGC-O, known as the buccal odour screening system (BOSS). Flavour and Fragrance Journal 19 (6):505–14. doi: 10.1002/ffj.1473.
   Web of Science ®Google Scholar
• Canon, F., F. Neiers, and E. Guichard. 2018. Saliva and flavor perception: Perspectives. Journal of Agricultural and Food Chemistry 66 (30):7873–9. doi: 10.1021/acs.jafc.8b01998.
   PubMed Web of Science ®Google Scholar
• Castagnola, M., E. Scarano, G. C. Passali, I. Messana, T. Cabras, F. Iavarone, G. Di Cintio, A. Fiorita, E. De Corso, and G. Paludetti. 2017. Salivary biomarkers and proteomics: Future diagnostic and clinical utilities. Acta Otorhinolaryngologica Italica: Organo Ufficiale Della Societa Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale 37 (2):94–101. doi: 10.14639/0392-100X-1598.
   PubMed Web of Science ®Google Scholar
• Castro, T. G., C. Silva, T. Matamá, and A. Cavaco-Paulo. 2021. The structural properties of odorants modulate their association to human odorant binding protein. Biomolecules 11 (2):145. doi: 10.3390/biom11020145.
   PubMed Web of Science ®Google Scholar
• Chen, J. 2009. Food oral processing - A review. Food Hydrocolloids 23 (1):1–25. doi: 10.1016/j.foodhyd.2007.11.013.
   Web of Science ®Google Scholar
• Ćorković, I., A. Pichler, J. Šimunović, and M. Kopjar. 2021. Hydrogels: Characteristics and application as delivery systems of phenolic and aroma compounds. Foods 10 (6):1252. doi: 10.3390/foods10061252.
   PubMed Web of Science ®Google Scholar
• Dehlholm, C. 2015. Free multiple sorting as a sensory profiling technique. In Rapid sensory profiling techniques, edited by J. Delarue, J. B. Lawlor, and M. Rogeaux, 187–96. Cambridge, UK: Woodhead Publishing. doi: 10.1533/9781782422587.2.187.
   Google Scholar
• Dinu, V., A. Gadon, K. Hurst, M. Lim, C. Ayed, R. B. Gillis, G. G. Adams, S. E. Harding, and I. D. Fisk. 2019. An enzymatically controlled mucoadhesive system for enhancing flavour during food oral processing. NPJ Science of Food 3 (1):11. doi: 10.1038/s41538-019-0043-y.
   PubMedGoogle Scholar
• Doyennette, M., C. De Loubens, I. Deleris, I. Souchon, and I. C. Trelea. 2011. Mechanisms explaining the role of viscosity and post-deglutitive pharyngeal residue on in vivo aroma release: A combined experimental and modeling study. Food Chemistry 128 (2):380–90. doi: 10.1016/j.foodchem.2011.03.039.
   PubMed Web of Science ®Google Scholar
• Dunkel, A., M. Steinhaus, M. Kotthoff, B. Nowak, D. Krautwurst, P. Schieberle, and T. Hofmann. 2014. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angewandte Chemie (International ed. in English) 53 (28):7124–43. doi: 10.1002/anie.201309508.
   PubMed Web of Science ®Google Scholar
• Edward, J. T. 1970. Molecular volumes and the Stokes-Einstein equation. Journal of Chemical Education 47 (4):261. doi: 10.1021/ed047p261.
   Web of Science ®Google Scholar
• Eldeghaidy, S., L. Marciani, J. C. Pfeiffer, J. Hort, K. Head, A. J. Taylor, R. C. Spiller, P. A. Gowland, and S. Francis. 2011. Use of an immediate swallow protocol to assess taste and aroma integration in fMRI studies. Chemosensory Perception 4 (4):163–74. doi: 10.1007/s12078-011-9094-4.
   Web of Science ®Google Scholar
• Esteban-Fernãndez, A., N. Rocha-Alcubilla, C. Munoz-Gonzalez, M. V. Moreno-Arribas, and M. A. Pozo-Bayon. 2016. Intra-oral adsorption and release of aroma compounds following in-mouth wine exposure. Food Chemistry 205:280–8. doi: 10.1016/j.foodchem.2016.03.030.
   PubMed Web of Science ®Google Scholar
• Feyzi, S., M. Varidi, M. R. Housaindokht, Z. Es’ haghi, R. Romano, P. Piombino, and A. Genovese. 2020. A study on aroma release and perception of saffron ice cream using in-vitro and in-vivo approaches. Innovative Food Science & Emerging Technologies 65:102455. doi: 10.1016/j.ifset.2020.102455v.
   Web of Science ®Google Scholar
• Freiherr, J. 2016. Cortical olfactory processing. In Hand book of odor, edited by A. Buettner, 759–64. Freising, Germany: Springer.
   Google Scholar
• Findlay, C. J. 2017. Dual-attribute time-intensity. In Time-dependent measures of perception in sensory evaluation, edited by H. Joanne, E. K. Sarah, and H. Tracey, 267–82. Hoboken, NJ, USA: John Wiley & Sons.
   Google Scholar
• Genovese, A., N. Caporaso, A. Civitella, and R. Sacchi. 2014. Effect of human saliva and sip volume of coffee brews on the release of key volatile compounds by a retronasal aroma simulator. Food Research International 61:100–11. doi: 10.1016/j.foodres.2014.02.034.
   Web of Science ®Google Scholar
• Genovese, A., N. Caporaso, V. Villani, A. Paduano, and R. Sacchi. 2015. Olive oil phenolic compounds affect the release of aroma compounds. Food Chemistry 181 (15):284–94. doi: 10.1016/j.foodchem.2015.02.097.
   PubMedGoogle Scholar
• Genovese, A., N. Caporaso, V. Bari, N. Yang, and I. Fisk. 2019. Effect of olive oil phenolic compounds on the aroma release and persistence from O/W emulsion analysed in vivo by APCI-MS. Food Research International (Ottawa, ON) 126:108686. doi: 10.1016/j.foodres.2019.108686.
   PubMed Web of Science ®Google Scholar
• Gisladottir, R. S., E. V. Ivarsdottir, A. Helgason, L. Jonsson, N. K. Hannesdottir, G. Rutsdottir, G. A. Arnadottir, A. Skuladottir, B. A. Jonsson, G. L. Norddahl, et al. 2020. Sequence variants in TAAR5 and other loci Affect human odor perception and naming. Current Biology 30 (23):4643–53.e3. doi: 10.1016/j.cub.2020.09.012.
   PubMed Web of Science ®Google Scholar
• Guo, Q. 2021. Understanding the oral processing of solid foods: Insights from food structure. Comprehensive Reviews in Food Science and Food Safety 20 (3):2941–67. doi: 10.1111/1541-4337.12745.
   PubMed Web of Science ®Google Scholar
• Haag, F., S. Hoffmann, and D. Krautwurst. 2021. Key food furanones furaneol and sotolone specifically activate distinct odorant receptors. Journal of Agricultural and Food Chemistry 69 (37):10999–1005. doi: 10.1021/acs.jafc.1c03314.
   PubMed Web of Science ®Google Scholar
• Hageman, J. H. J., A. G. Nieuwenhuizen, S. M. Ruth, J. A. Hageman, and J. Keijer. 2019. Application of volatile organic compound analysis in a nutritional intervention study, differential responses during five hours following consumption of a high‐and a low‐fat dairy drink. Molecular Nutrition & Food Research 63 (20):1900189. doi: 10.1002/mnfr.201900189.
   PubMed Web of Science ®Google Scholar
• Hansel, A., A. Jordan, R. Holzinger, P. Prazeller, W. Vogel, and W. Lindinger. 1995. Proton transfer reaction mass spectrometry: On-line trace gas analysis at the ppb level. International Journal of Mass Spectrometry and Ion Processes 149–150:609–19. doi: 10.1016/0168-1176(95)04294-U.
   Web of Science ®Google Scholar
• Heilig, A., A. Sonne, P. Schieberle, and J. Hinrichs. 2016. Determination of aroma compound partition coefficients in aqueous, polysaccharide, and dairy matrices using the phase ratio variation method: A review and modeling approach. Journal of Agricultural and Food Chemistry 64 (22):4450–70. doi: 10.1021/acs.jafc.6b01482.
   PubMed Web of Science ®Google Scholar
• Heilmann, S., and T. Hummel. 2004. A new method for comparing orthonasal and retronasal olfaction. Behavioral Neuroscience 118 (2):412–9. doi: 10.1142/S0218271808012188[PMC].[15113268].
   PubMed Web of Science ®Google Scholar
• How, M. S., J. R. Jones, M. P. Morgenstern, E. Gray-Stuart, J. E. Bronlund, A. Saint-Eve, I. C. Trelea, and I. Souchon. 2021. Modelling the role of oral processing on in vivo aroma release of white rice: Conceptual model and experimental validation. LWT 141:110918. doi: 10.1016/j.lwt.2021.110918.
   Web of Science ®Google Scholar
• Iravani, B., A. Arshamian, K. Ohla, D. A. Wilson, and J. N. Lundstrom. 2019. Non-invasive recording from the human olfactory bulb. Nature Communications 11 (1):506–19. doi: 10.1038/s41467-020-14520-9.
   Web of Science ®Google Scholar
• Itobe, T., O. Nishimura, and K. Kumazawa. 2015. Influence of milk on aroma release and aroma perception during consumption of coffee beverages. Food Science and Technology Research 21 (4):607–14. doi: 10.3136/fstr.21.607.
   Web of Science ®Google Scholar
• Jacobson, A., E. Green, L. Haase, J. Szajer, and C. Murphy. 2019. Differential effects of BMI on brain response to odor in olfactory, reward and memory regions: Evidence from fMRI. Nutrients 11 (4):926. doi: 10.3390/nu11040926.
   PubMed Web of Science ®Google Scholar
• Jaeger, S. R., M. K. Beresford, D. C. Hunter, F. Alcaire, J. C. Castura, and G. Ares. 2017. Does a familiarization step influence results from a TCATA task? Food Quality and Preference 55:91–7. doi: 10.1016/j.foodqual.2016.09.001.
   Web of Science ®Google Scholar
• Javaid, M. A., A. S. Ahmed, R. Durand, and S. D. Tran. 2016. Saliva as a diagnostic tool for oral and systemic diseases. Journal of Oral Biology and Craniofacial Research 6 (1):67–76. doi: 10.1016/j.jobcr.2015.08.006.
   Google Scholar
• Jordan, A., S. Haidacher, G. Hanel, E. Hartungen, L. Märk, H. Seehauser, R. Schottkowsky, P. Sulzer, and T. D. Märk. 2009. A high resolution and high sensitivity proton-transfer-reaction time-of-flight mass spectrometer (PTR-TOF-MS). International Journal of Mass Spectrometry 286 (2–3):122–8. doi: 10.1016/j.ijms.2009.07.005.
   Web of Science ®Google Scholar
• Keller, A., H. Zhuang, Q. Chi, L. B. Vosshall, and H. Matsunami. 2007. Genetic variation in a human odorant receptor alters odour perception. Nature 449 (7161):468–72. doi: 10.1038/nature06162.
   PubMed Web of Science ®Google Scholar
• Khramova, D. S., and S. V. Popov. 2022. A secret of salivary secretions: Multimodal effect of saliva in sensory perception of food. European Journal of Oral Sciences 130 (2):e12846. doi: 10.1111/eos.12846.
   PubMed Web of Science ®Google Scholar
• Kowalewski, J., and A. Ray. 2020. Predicting human olfactory perception from activities of odorant receptors. iScience 23 (8):101361. doi: 10.1016/j.isci.2020.101361.
   PubMed Web of Science ®Google Scholar
• Konitzer, K., T. Pflaum, P. Oliveira, E. Arendt, P. Koehler, and T. Hofmann. 2013. Kinetics of sodium release from wheat bread crumb as affected by sodium distribution. Journal of Agricultural and Food Chemistry 61 (45):10659–69. doi: 10.1021/jf404458v.
   PubMed Web of Science ®Google Scholar
• Krause, A. J., L. S. Henson, and G. A. Reineccius. 2011. Use of a chewing device to perform a mass balance on chewing gum components. Flavour and Fragrance Journal 26 (1):47–54. doi: 10.1002/ffj.2015.
   Web of Science ®Google Scholar
• Lafarge, C., M. H. Bard, A. Breuvart, J. L. Doublier, and N. Cayot. 2008. Influence of the structure of cornstarch dispersions on kinetics of aroma release. Journal of Food Science 73 (2):S104–S109. doi: 10.1111/j.1750-3841.2007.00645.x.
   PubMed Web of Science ®Google Scholar
• Lagg, A., J. Taucher, A. Hansel, and W. Lindinger. 1994. Applications of proton transfer reactions to gas analysis. International Journal of Mass Spectrometry and Ion Processes 134 (1):55–66. doi: 10.1016/0168-1176(94)03965-8.
   Web of Science ®Google Scholar
• Langford, V. S., D. Padayachee, M. J. McEwan, and S. A. Barringer. 2019. Comprehensive odorant analysis for on‐line applications using selected ion flow tube mass spectrometry (SIFT‐MS). Flavour and Fragrance Journal 34 (6):393–410. doi: 10.1002/ffj.3516.
   Web of Science ®Google Scholar
• Lesme, H., C. Alleaume, S. Bouhallab, M.-H. Famelart, C. Marzin, L. Lopez-Torres, C. Prost, and C. Rannou. 2020a. Aroma-retention capacities of functional whey protein aggregates: Study of a strawberry aroma in solutions and in fat-free yogurts. Food Research International (Ottawa, ON) 136:109491. doi: 10.1016/j.foodres.2020.109491.
   PubMed Web of Science ®Google Scholar
• Lesme, H., C. Rannou, M. H. Famelart, S. Bouhallab, and C. Prost. 2020b. Yogurts enriched with milk proteins: Texture properties, aroma release and sensory perception. Trends in Food Science & Technology 98:140–9. doi: 10.1016/j.tifs.2020.02.006.
   Web of Science ®Google Scholar
• Linforth, R. S. T., and A. J. Taylor. 1999. Apparatus and methods for the; analysis of trace constituents of gases. U.S. Patent; EP0819937A2.
   Google Scholar
• Liu, J., and Y. Duan. 2012. Saliva: A potential media for disease diagnostics and monitoring. Oral Oncology 48 (7):569–77. doi: 10.1016/j.oraloncology.2012.01.021.
   PubMed Web of Science ®Google Scholar
• Liu, J., W. L. Bredie, E. Sherman, J. F. Harbertson, and H. Heymann. 2018. Comparison of rapid descriptive sensory methodologies: Free-choice profiling, flash profile and modified flash profile. Food Research International (Ottawa, ON) 106:892–900. doi: 10.1016/j.foodres.2018.01.062.
   PubMed Web of Science ®Google Scholar
• Luckett, C. R., and H. S. Seo. 2017. The effects of both chewing rate and chewing duration on temporal flavor perception. Chemosensory Perception 10 (1–2):13–22. doi: 10.1007/s12078-017-9224-8.
   Web of Science ®Google Scholar
• Ma, W., D. Zhang, M. Hu, P. J. Wilde, J. Wu, L. Zhao, T. Ma, X. Wang, and J. Chen. 2021. Comparison of oral physiological and salivary rheological properties of Chinese Mongolian and Han young adults. Archives of Oral Biology 123:105033. doi: 10.1016/J.ARCHORALBIO.2020.105033.
   PubMed Web of Science ®Google Scholar
• Mao, L., Y. H. Roos, C. G. Biliaderis, and S. Miao. 2017. Food emulsions as delivery systems for flavor compounds: A review. Critical Reviews in Food Science and Nutrition 57 (15):3173–87. doi: 10.1080/10408398.2015.1098586.
   PubMed Web of Science ®Google Scholar
• María, P. J., M. G. Carolina, and P. B. M. Ángeles. 2020. Understanding human salivary esterase activity and its variation under wine consumption conditions. RSC Advances 10 (41):24352–61. doi: 10.1039/D0RA04624H.
   PubMed Web of Science ®Google Scholar
• de March, C. A., W. B. Titlow, T. Sengoku, P. Breheny, H. Matsunami, and T. S. McClintock. 2020. Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures. Molecular and Cellular Neurosciences 104:103469. doi: 10.1016/j.mcn.2020.103469.
   PubMed Web of Science ®Google Scholar
• McClintock, T. S., K. Adipietro, W. B. Titlow, P. Breheny, A. Walz, P. Mombaerts, and H. Matsunami. 2014. In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors. The Journal of Neuroscience 34 (47):15669–78. doi: 10.1523/JNEUROSCI.3625-14.2014.
   PubMed Web of Science ®Google Scholar
• Muñoz-González, C., G. Feron, and F. Canon. 2018. Main effects of human saliva on flavour perception and the potential contribution to food consumption. The Proceedings of the Nutrition Society 77 (4):423–31. doi: 10.1017/S0029665118000113.
   PubMed Web of Science ®Google Scholar
• Muñoz-González, C., M. Brulé, G. Feron, and F. Canon. 2019. Does interindividual variability of saliva affect the release and metabolization of aroma compounds ex vivo? the particular case of elderly suffering or not from hyposalivation. Journal of Texture Studies 50 (1):36–44. doi: 10.1111/jtxs.12382.
   PubMed Web of Science ®Google Scholar
• Muñoz-González, C., G. Feron, and F. Canon. 2021. Physiological and oral parameters contribute prediction of retronasal aroma release in an elderly cohort. Food Chemistry 342 (10):128355. doi: 10.1016/j.foodchem.2020.128355.
   PubMedGoogle Scholar
• Muñoz-González, C., M. Brule, C. Martin, G. Feron, and F. Canon. 2022. Molecular mechanisms of aroma persistence: From noncovalent interactions between aroma compounds and the oral mucosa to metabolization of aroma compounds by saliva and oral cells. Food Chemistry 373 (Pt B):131467. doi: 10.26434/chemrxiv.14595606.
   PubMedGoogle Scholar
• Ni, R., M. H. Michalski, E. Brown, N. Doan, J. Zinter, N. T. Ouellette, and G. M. Shepherd. 2015. Optimal directional volatile transport in retronasal olfaction. Proceedings of the National Academy of Sciences of the United States of America 112 (47):14700–4. doi: 10.1073/pnas.1511495112.
   PubMed Web of Science ®Google Scholar
• Normand, V., S. Avison, and A. Parker. 2004. Modeling the kinetics of flavour release during drinking. Chemical Senses 29 (3):235–45. doi: 10.1093/chemse/bjh028.
   PubMed Web of Science ®Google Scholar
• Okawa, J., K. Hori, T. Yoshimoto, S. E. Salazar, and T. Ono. 2021. Higher masticatory performance and higher number of chewing strokes increase retronasal aroma. Frontiers in Nutrition 8:623507. doi: 10.3389/fnut.2021.623507[PMC].[33738295].
   PubMed Web of Science ®Google Scholar
• Pagès-Hélary, S., I. Andriot, E. Guichard, and F. Canon. 2014. Retention effect of human saliva on aroma release and respective contribution of salivary mucin and a-amylase. Food Research International (Ottawa, ON) 64:424–31. doi: 10.1016/j.foodres.2014.07.013.
   PubMed Web of Science ®Google Scholar
• Panda, S., J. Chen, and O. Benjamin. 2020. Development of model mouth for food oral processing studies: Present challenges and scopes. Innovative Food Science & Emerging Technologies 66 (1):102524. doi: 10.1016/j.ifset.2020.102524.
   Google Scholar
• Patin, A., and B. M. Pause. 2015. Human amygdala activations during nasal chemoreception. Neuropsychologia 78:171–94. doi: 10.1016/j.neuropsychologia.2015.10.009.
   PubMed Web of Science ®Google Scholar
• Gonçalves, F., A. Ribeiro, C. Silva, and A. Cavaco-Paulo. 2021. Biotechnological applications of mammalian odorant-binding proteins. Critical Reviews in Biotechnology 41 (3):441–55. doi: 10.1080/07388551.2020.1853672.
   PubMed Web of Science ®Google Scholar
• Peyron, M.-A., V. Santé-Lhoutellier, D. Dardevet, M. Hennequin, D. Rémond, O. François, and A. Woda. 2019. Addressing various challenges related to food bolus and nutrition with the AM2 mastication simulator. Food Hydrocolloids 97:105229. doi: 10.1016/j.foodhyd.2019.105229.
   Web of Science ®Google Scholar
• Pedersen, A. M. L., C. E. Sørensen, G. B. Proctor, G. H. Carpenter, and J. Ekström. 2018. Salivary secretion in health and disease. Journal of Oral Rehabilitation 45 (9):730–46. doi: 10.1111/joor.12664.
   PubMed Web of Science ®Google Scholar
• Pedrotti, M., A. Spaccasassi, F. Biasioli, and V. Fogliano. 2019. Ethnicity, gender and physiological parameters: Their effect on in vivo flavour release and perception during chewing gum consumption. Food Research International (Ottawa, ON) 116:57–70. doi: 10.1016/j.foodres.2018.12.019.
   PubMed Web of Science ®Google Scholar
• Ployon, S., M. Morzel, and F. Canon. 2017. The role of saliva in aroma release and perception. Food Chemistry 226 (1):212–20. doi: 10.1016/j.foodchem.2017.01.055.
   PubMedGoogle Scholar
• Ployon, S., M. Brule, I. Andriot, M. Morzel, and F. Canon. 2020. Understanding retention and metabolization of aroma compounds using an in vitro model of oral mucosa. Food Chemistry 318:126468. doi: 10.1016/j.foodchem.2020.126468.
   PubMed Web of Science ®Google Scholar
• Polster, J., and P. Schieberle. 2015. Structure–odor correlations in homologous series of alkanethiols and attempts to predict odor thresholds by 3D-QSAR studies. Journal of Agricultural and Food Chemistry 63 (5):1419–32. doi: 10.1021/jf506135c.
   PubMed Web of Science ®Google Scholar
• Porada, D. K., C. Regenbogen, J. Seubert, J. Freiherr, and J. N. Lundström. 2019. Multisensory enhancement of odor object processing in primary olfactory cortex. Neuroscience 418:254–65. doi: 10.1016/j.neuroscience.2019.08.040.
   PubMed Web of Science ®Google Scholar
• Pineau, N., P. Schlich, S. Cordelle, C. Mathonnière, S. Issanchou, A. Imbert, M. Rogeaux, P. Etiévant, and E. Köster. 2009. Temporal dominance of sensations: Construction of the TDS curves and comparison with time–intensity. Food Quality and Preference 20 (6):450–5. doi: 10.1016/j.foodqual.2009.04.005.
   Web of Science ®Google Scholar
• Piombino, P., L. Moio, and A. Genovese. 2019. Orthonasal vs. retronasal: Studying how volatiles’ hydrophobicity and matrix composition modulate the release of wine odorants in simulated conditions. Food Research International (Ottawa, ON) 116:548–58. doi: 10.1016/j.foodres.2018.08.072.
   PubMed Web of Science ®Google Scholar
• Piombino, P., A. Genovese, S. Esposito, L. Moio, P. P. Cutolo, A. Chambery, V. Severino, E. Moneta, D. P. Smith, S. M. Owens, et al. 2014. Saliva from obese individuals suppresses the release of aroma compounds from wine. PLoS One 9 (1):e85611. doi: 10.1371/journal.pone.0085611.
   PubMed Web of Science ®Google Scholar
• Pu, D., H. Zhang, Y. Zhang, B. Sun, F. Ren, H. Chen, and J. He. 2019a. Characterization of the aroma release and perception of white bread during oral processing by gas chromatography-ion mobility spectrometry and temporal dominance of sensations analysis. Food Research International (Ottawa, ON) 123:612–22. doi: 10.1016/j.foodres.2019.05.016.
   PubMed Web of Science ®Google Scholar
• Pu, D., H. Zhang, Y. Zhang, B. Sun, F. Ren, H. Chen, and J. Xie. 2019b. Characterization of the oral breakdown, sensory properties, and volatile release during mastication of white bread. Food Chemistry 298 (15):125003. doi: 10.1016/j.foodchem.2019.125003.
   PubMedGoogle Scholar
• Pu, D., W. Duan, Y. Huang, Y. Zhang, B. Sun, F. Ren, H. Zhang, H. Chen, J. He, and Y. Tang. 2020. Characterization of the key odorants contributing to retronasal olfaction during bread consumption. Food Chemistry 318:126520. doi: 10.1016/j.foodchem.2020.126520.
   PubMed Web of Science ®Google Scholar
• Pu, D., Y. Zhang, B. Sun, F. Ren, H. Zhang, H. Chen, and Y. Tang. 2021a. Characterization of the key taste compounds during bread oral processing by instrumental analysis and dynamic sensory evaluation. LWT 138:110641. doi: 10.1016/j.lwt.2020.110641.
   Web of Science ®Google Scholar
• Pu, D., W. Duan, Y. Huang, L. Zhang, Y. Zhang, B. Sun, F. Ren, H. Zhang, and Y. Tang. 2021b. Characterization of the dynamic texture perception and the impact factors on the bolus texture changes during oral processing. Food Chemistry 339:128078. doi: 10.1016/j.foodchem.2020.128078.
   PubMed Web of Science ®Google Scholar
• Raithore, S., and D. G. Peterson. 2016. Delivery of taste and aroma components in sugar-free chewing gum, mass balance analysis. Chemosensory Perception 9 (4):182–92. doi: 10.1007/s12078-016-9218-y.
   Web of Science ®Google Scholar
• Raithore, S., and D. G. Peterson. 2018. Effects of polyol type and particle size on flavor release in chewing gum. Food Chemistry 253:293–9. doi: 10.1016/j.foodchem.2018.01.123.
   PubMed Web of Science ®Google Scholar
• Salles, C., P. Mielle, L. Q. Jean-Luc, R. Renaud, and J. J. Liodenot. 2006. A novel prototype to closely mimic mastication for in vitro dynamic measurements of flavour release. Developments in Food Science 43:581–4. doi: 10.1016/S0167-4.501(06)80137-8.
   Google Scholar
• Salles, C., A. Tarrega, P. Mielle, J. Maratray, P. Gorria, J. Liaboeuf, and J.-J. Liodenot. 2007. Development of a chewing simulator for food breakdown and the analysis of in vitro flavor compound release in a mouth environment. Journal of Food Engineering 82 (2):189–98. doi: 10.1016/j.jfoodeng.2007.02.008.
   Web of Science ®Google Scholar
• Sanganahalli, B. G., K. L. Baker, G. J. Thompson, P. Herman, G. M. Shepherd, J. V. Verhagen, and F. Hyder. 2020. Orthonasal versus retronasal glomerular activity in rat olfactory bulb by fMRI. NeuroImage 212:116664. 10.1016/j.neuroimage.2020.116664.
   PubMed Web of Science ®Google Scholar
• Schiefner, A., R. Freier, A. Eichinger, and A. Skerra. 2015. Crystal structure of the human odorant binding protein, OBPIIa. Proteins: Structure, Function, and Bioinformatics 83 (6):1180–4. 10.1002/prot.24797.
   PubMed Web of Science ®Google Scholar
• Schwartz, M., F. Canon, G. Feron, F. Neiers, and A. Gamero. 2021. Impact of oral microbiota on flavor perception: From food processing to in-mouth metabolization. Foods 10 (9):2006. doi: 10.3390/foods10092006.
   PubMed Web of Science ®Google Scholar
• Shirasu, M., K. Yoshikawa, Y. Takai, A. Nakashima, H. Takeuchi, H. Sakano, and K. Touhara. 2014. Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors. Neuron 81 (1):165–78. 10.1016/j.neuron.2013.10.021.
   PubMed Web of Science ®Google Scholar
• Singh, V., N. R. Murphy, V. Balasubramanian, and J. D. Mainland. 2019. Competitive binding predicts nonlinear responses of olfactory receptors to complex mixtures. Proceedings of the National Academy of Sciences 116 (19):9598–603. doi: 10.1073/pnas.1813230116.
   PubMed Web of Science ®Google Scholar
• Skamniotis, C. G., M. Elliott, and M. N. Charalambides. 2019. Computer simulations of food oral processing to engineer teeth cleaning. Nature Communications 10 (1):3571. doi: 10.1038/s41467-019-11288-5.
   PubMedGoogle Scholar
• Small, D. M., J. C. Gerber, Y. E. Mak, and T. Hummel. 2005. Differential neural responses evoked by orthonasal versus retronasal odorant perception in humans. Neuron 47 (4):593–605. 10.1016/j.neuron.2005.07.022.
   PubMed Web of Science ®Google Scholar
• Smith, D., and P. Spanel. 1996. The novel selected-ion flow tube approach to trace gas analysis of air and breath. Rapid Communications in Mass Spectrometry 10 (10):1183–98. doi: 10.1002/rcm.3434.
   PubMed Web of Science ®Google Scholar
• Smith, D., T. Wang, A. Pysanenko, and P. Spanel. 2008. A selected ion flow tube mass spectrometry study of ammonia in mouth-and nose-exhaled breath and in the oral cavity. Rapid Communications in Mass Spectrometry : RCM 22 (6):783–9.
   PubMed Web of Science ®Google Scholar
• Sowndhararajan, K., H. Cho, B. Yu, and S. Kim. 2015. Effect of olfactory stimulation of isomeric aroma compounds, (+)-limonene and terpinolene on human electroencephalographic activity. European Journal of Integrative Medicine 7 (6):561–6. doi: 10.1016/j.eujim.2015.08.006.
   Web of Science ®Google Scholar
• Spence, C. 2021. What is the relationship between the presence of volatile organic compounds in food and drink products and multisensory flavour perception? Foods 10 (7):1570. doi: 10.3390/foods10071570.
   PubMed Web of Science ®Google Scholar
• Tan, Y., and K. J. Siebert. 2004. Quantitative structure-activity relationship modeling of alcohol, ester, aldehyde, and ketone flavor thresholds in beer from molecular features. Journal of Agricultural and Food Chemistry 52 (10):3057–64. doi: 10.1021/jf035149j.
   PubMed Web of Science ®Google Scholar
• Trelea, I. C., S. Atlan, I. Déléris, A. Saint-Eve, M. Marin, and I. Souchon. 2008. Mechanistic mathematical model for in vivo aroma release during eating of semiliquid foods. Chemical Senses 33 (2):181–92. 10.1093/chemse/bjm077.
   PubMed Web of Science ®Google Scholar
• Tarrega, A., C. Yven, E. Semon, and C. Salles. 2011. In-mouth aroma compound release during cheese consumption: Relationship with food bolus formation. International Dairy Journal 21 (5):358–64. doi: 10.1016/j.idairyj.2010.12.010.
   Web of Science ®Google Scholar
• Tarrega, A., C. Yven, E. Semon, P. Mielle, and C. Salles. 2019. Effect of oral physiology parameters on in-mouth aroma compound release using lipoprotein matrices: An in vitro approach. Foods 8 (3):106. doi: 10.3390/foods8030106.
   PubMed Web of Science ®Google Scholar
• Trimmer, C., L. L. Snyder, and J. D. Mainland. 2014. High-throughput analysis of mammalian olfactory receptors: Measurement of receptor activation via luciferase activity. Journal of Visualized Experiments 88 (88):e5164. doi: 10.3791/51640.
   Google Scholar
• Trimmer, C., and J. D. Mainland. 2017. The olfactory system. In Conn’s translational neuroscience, edited by P. Michael Conn, 363–77. Texas, USA: Academic Press.
   Google Scholar
• van Eck, A., and M. Stieger. 2020. Oral processing behavior, sensory perception and intake of composite foods. Trends in Food Science & Technology 106:219–31. doi: 10.1016/j.tifs.2020.10.008.
   Web of Science ®Google Scholar
• van Ruth, S. M., C. King, and P. Giannouli. 2002. Influence of lipid fraction, emulsifier fraction, and mean particle diameter of oil-in-water emulsions on the release of 20 aroma compounds. Journal of Agricultural and Food Chemistry 50 (8):2365–71. doi: 10.1021/jf011072s.
   PubMed Web of Science ®Google Scholar
• Weterings, M., I. Bodnár, R. M. Boom, and M. Beyrer. 2020. A classification scheme for interfacial mass transfer and the kinetics of aroma release. Trends in Food Science & Technology 105:433–48. doi: 10.1016/j.tifs.2019.04.012.
   Web of Science ®Google Scholar
• Xu, Y., J. Zhao, X. Liu, C. Zhang, Z. Zhao, X. Li, and B. Sun. 2022a. Flavor mystery of Chinese traditional fermented baijiu: The great contribution of ester compounds. Food Chemistry 369:130920. 10.1016/j.foodchem.2021.130920.
   PubMed Web of Science ®Google Scholar
• Xu, Y., J. Zhao, H. Huang, X. Guo, X. Li, W. Zou, W. Li, C. Zhang, and M. Huang. 2022b. Biodegradation of phthalate esters by Pantoea dispersa BJQ0007 isolated from Baijiu. Journal of Food Composition and Analysis 105:104201. doi: 10.1016/j.jfca.2021.104201.
   Web of Science ®Google Scholar
• Yang, Z. Y., Y. G. Fan, M. Xu, J. N. Ren, Y. L. Liu, L. L. Zhang, J. J. Li, Y. Zhang, M. Dong, and G. Fan. 2017. Effects of xanthan and sugar on the release of aroma compounds in model solution. Flavour and Fragrance Journal 32 (2):112–8. doi: 10.1002/ffj.3360.
   Web of Science ®Google Scholar
• Yamada, Y., K. Bhaukaurally, T. J. Madarász, A. Pouget, I. Rodriguez, and A. Carleton. 2017. Context- and output layer-dependent long-term ensemble plasticity in a sensory circuit. Neuron 93 (5):1198–212.e5. 10.1016/j.neuron.2017.02.006.
   PubMed Web of Science ®Google Scholar
• Yao, F., Y. Ye, and W. Zhou. 2020. Nasal airflow engages central olfactory processing and shapes olfactory percepts. Proceedings of the Royal Society B: Biological Sciences 287 (1937):20201772. 10.1098/rspb.2020.1772.
   PubMed Web of Science ®Google Scholar
• Yen, C. I., S. H. Mao, C. H. Chen, C. T. Chen, and M. Y. Lee. 2015. The correlation between surface electromyography and bite force of mastication muscles in Asian young adults. Annals of Plastic Surgery 74 (Supplement 2):S168–S172. doi: 10.1097/SAP.0000000000000468.
   PubMedGoogle Scholar
• Zhang, J., D. C. Kang, W. G. Zhang, and J. M. Lorenzo. 2021. Recent advantage of interactions of protein-flavor in foods: Perspective of theoretical models, protein properties and extrinsic factors. Trends in Food Science & Technology 111:405–25. doi: 10.1016/j.tifs.2021.02.060.
   Web of Science ®Google Scholar
• Zhou, L., J. Zhang, L. J. Xing, and W. G. Zhang. 2021. Applications and effects of ultrasound assisted emulsification in the production of food emulsions: A review. Trends in Food Science & Technology 110:493–512. doi: 10.1016/j.tifs.2021.02.008.
   Web of Science ®Google Scholar