Analysis of per- and polyfluoroalkyl substances (PFAS) in raw materials intended for the production of paper-based food contact materials – evaluating LC-MS/MS versus total fluorine and extractable organic fluorine

References

• Al Amin M, Sobhani Z, Liu Y, Dharmaraja R, Chadalavada S, Naidu R, Chalker JM, Fang C. 2020. Recent advances in the analysis of per- and polyfluoroalkyl substances (PFAS)—a review. Environ Technol Innov. 19:100879. doi: 10.1016/j.eti.2020.100879.
   Web of Science ®Google Scholar
• Appleman TD, Higgins CP, Quiñones O, Vanderford BJ, Kolstad C, Zeigler-Holady JC, Dickenson ERV. 2014. Treatment of poly- and perfluoroalkyl substances in U.S. full-scale water treatment systems. Water Res. 51:246–255. https://www.sciencedirect.com/science/article/pii/S0043135413008932. doi: 10.1016/j.watres.2013.10.067.
   PubMed Web of Science ®Google Scholar
• Aro R, Eriksson U, Kärrman A, Chen F, Wang T, Yeung LWY. 2021. Fluorine mass balance analysis of effluent and sludge from Nordic countries. ACS Est Water. 1(9):2087–2096. doi: 10.1021/acsestwater.1c00168.
   Google Scholar
• Bečanová J, Melymuk L, Vojta Š, Komprdová K, Klánová J. 2016. Screening for perfluoroalkyl acids in consumer products, building materials and wastes. Chemosphere. 164:322–329. https://www.sciencedirect.com/science/article/pii/S004565351631147X. doi: 10.1016/j.chemosphere.2016.08.112.
   PubMed Web of Science ®Google Scholar
• Begley TH, White K, Honigfort P, Twaroski ML, Neches R, Walker RA. 2005. Perfluorochemicals: potential sources of and migration from food packaging. Food Addit Contam. 22(10):1023–1031. doi: 10.1080/02652030500183474.
   PubMed Web of Science ®Google Scholar
• Berger U, Glynn A, Holmström KE, Berglund M, Ankarberg EH, Törnkvist A. 2009. Fish consumption as a source of human exposure to perfluorinated alkyl substances in Sweden – analysis of edible fish from Lake Vättern and the Baltic Sea. Chemosphere. 76(6):799–804. https://www.sciencedirect.com/science/article/pii/S0045653509005268. doi: 10.1016/j.chemosphere.2009.04.044.
   PubMed Web of Science ®Google Scholar
• Bloom C, Hanssen L. 2015. Analysis of short – chain per- and polyfluorinated chemicals. Copenhagen: Nordic Council of Ministers.
   Google Scholar
• Bokkers BGH, van de Ven B, Janssen P, Bil W, van Broekhuizen F, Zeilmaker M, Oomen AG. 2019. Per- and polyfluoroalkyl substances (PFASs) in food contact materials. www.rivm.nl/en.: National Institute for Public Health and the Environment.
   Google Scholar
• Charbonnet JA, Rodowa AE, Joseph NT, Guelfo JL, Field JA, Jones GD, Higgins CP, Helbling DE, Houtz EF. 2021. Environmental source tracking of per- and polyfluoroalkyl substances within a forensic context: current and future techniques. Environ Sci Technol. 55(11):7237–7245. doi: 10.1021/acs.est.0c08506.
   PubMed Web of Science ®Google Scholar
• Crone BC, Speth TF, Wahman DG, Smith SJ, Abulikemu G, Kleiner EJ, Pressman JG. 2019. Occurrence of per- and polyfluoroalkyl substances (pfas) in source water and their treatment in drinking water. Crit Rev Environ Sci Technol. 49(24):2359–2396. doi: 10.1080/10643389.2019.1614848.
   PubMed Web of Science ®Google Scholar
• Curtzwiler GW, Silva P, Hall A, Ivey A, Vorst K. 2021. Significance of perfluoroalkyl substances (PFAS) in food packaging. Integr Environ Assess Manag. 17(1):7–12. doi: 10.1002/ieam.4346.
   PubMed Web of Science ®Google Scholar
• Danish Veterinary and Food Administration. 2020. Order on food contact materials and on provisions for penalties for breaches of related EU legislation. Denmark: European Commission.
   Google Scholar
• Domingo JL, Nadal M. 2019. Human exposure to per- and polyfluoroalkyl substances (PFAS) through drinking water: a review of the recent scientific literature. Environ Res. 177:108648. https://www.sciencedirect.com/science/article/pii/S0013935119304451. doi: 10.1016/j.envres.2019.108648.
   PubMed Web of Science ®Google Scholar
• Elizalde MP, Gómez-Lavín S, Urtiaga AM. 2018. Migration of perfluorinated compounds from paperbag to Tenax® and lyophilised milk at different temperatures. Int J Environ Anal Chem. 98(15):1423–1433. doi: 10.1080/03067319.2018.1562062.
   Web of Science ®Google Scholar
• Environmental Protection Agency. 2021. Navigation panel to PFAS structure lists. https://www.epa.gov/:. US EPA. https://comptox.epa.gov/dashboard/chemical-lists/PFASSTRUCT.
   Google Scholar
• European Commission. 2011. Commission Regulation (EU) No. 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food. Off J European Union. 54:L12/1.
   Google Scholar
• EURL for Halogenated POPs in Feed and Food. 2022. Guidance document on analytical parameters for the determination of per- and polyfluoroalkyl substances (PFAS) in food and feed. European Union Reference Laboratory for halogenated POPs in Feed and Food.
   Google Scholar
• European Environment Agency. 2023. Emerging chemical risks in Europe—‘PFAS’. en. https://www.eea.europa.eu/publications/emerging-chemical-risks-in-europe.
   Google Scholar
• European Food Safety Authority. 2020. PFAS in food: EFSA assesses risks and sets tolerable intake. [accessed 2023 Apr 25/11:37:29]. https://www.efsa.europa.eu/en/news/pfas-food-efsa-assesses-risks-and-sets-tolerable-intake.
   Google Scholar
• Fenton SE, Ducatman A, Boobis A, DeWitt JC, Lau C, Ng C, Smith JS, Roberts SM. 2021. Per- and polyfluoroalkyl substance toxicity and human health review: current state of knowledge and strategies for informing future research. Environ Toxicol Chem. 40(3):606–630. doi: 10.1002/etc.4890.
   PubMed Web of Science ®Google Scholar
• Fiedler H, Kennedy T, Henry BJ. 2021. A critical review of a recommended analytical and classification approach for organic fluorinated compounds with an emphasis on per- and polyfluoroalkyl substances. Integr Environ Assess Manag. 17(2):331–351. doi: 10.1002/ieam.4352.
   PubMed Web of Science ®Google Scholar
• Gebbink WA, Glynn A, Darnerud PO, Berger U. 2015. Perfluoroalkyl acids and their precursors in Swedish food: the relative importance of direct and indirect dietary exposure. Environ Pollut. 198:108–115. https://www.sciencedirect.com/science/article/pii/S0269749114005223. doi: 10.1016/j.envpol.2014.12.022.
   PubMed Web of Science ®Google Scholar
• Gebbink WA, Ullah S, Sandblom O, Berger U. 2013. Polyfluoroalkyl phosphate esters and perfluoroalkyl carboxylic acids in target food samples and packaging-method development and screening. Environ Sci Pollut Res Int. 20(11):7949–7958. doi: 10.1007/s11356-013-1596-y.
   PubMed Web of Science ®Google Scholar
• Glenn G, Shogren R, Jin X, Orts W, Hart‐Cooper W, Olson L. 2021. Per‐ and polyfluoroalkyl substances and their alternatives in paper food packaging. Comp Rev Food Sci Food Safe. 20(3):2596–2625. doi: 10.1111/1541-4337.12726.
   PubMed Web of Science ®Google Scholar
• Glüge J, Scheringer M, Cousins IT, DeWitt JC, Goldenman G, Herzke D, Lohmann R, Ng CA, Trier X, Wang Z. 2020. An overview of the uses of per- and polyfluoroalkyl substances (PFAS). Environ Sci Process Impacts. 22(12):2345–2373. doi: 10.1039/d0em00291g.
   PubMed Web of Science ®Google Scholar
• Göckener B, Fliedner A, Weinfurtner K, Rüdel H, Badry A, Koschorreck J. 2023. Tracking down unknown PFAS pollution – The direct TOP assay in spatial monitoring of surface waters in Germany. Sci Total Environ. 898:165425. https://www.sciencedirect.com/science/article/pii/S0048969723040482. doi: 10.1016/j.scitotenv.2023.165425.
   PubMed Web of Science ®Google Scholar
• Granby K, Tesdal Håland J. 2018. Per- and polyfluorinated alkyl substances (PFAS) in paper and board food contact materials – selected samples from the Norwegian market 2017. Technical University of Denmark: Norwegian Food Safety Authority. https://backend.orbit.dtu.dk/ws/files/192717049/Per_and_polyfluorinated_alkyl_substances_PFAS_in_paper_and_board_Food_Contact_Materials_2017.pdf.
   Google Scholar
• Herzke D, Huber S, Bervoets L, D'Hollander W, Hajslova J, Pulkrabova J, Brambilla G, Filippis S. d, Klenow S, Heinemeyer G, et al. 2013. Perfluorinated alkylated substances in vegetables collected in four European countries; occurrence and human exposure estimations. Environ Sci Pollut Res Int. 20(11):7930–7939. doi: 10.1007/s11356-013-1777-8.
   PubMed Web of Science ®Google Scholar
• Key BD, Howell RD, Criddle CS. 1997. Fluorinated organics in the biosphere. Environ Sci Technol. 31(9):2445–2454. doi: 10.1021/es961007c.
   Web of Science ®Google Scholar
• Langberg HA, Arp HPH, Castro G, Asimakopoulos AG, Knutsen H. 2024. Recycling of paper, cardboard and its PFAS in Norway. J Hazard Mater Lett. 5:100096. https://www.sciencedirect.com/science/article/pii/S2666911023000229. doi: 10.1016/j.hazl.2023.100096.
   Google Scholar
• Martínez-Moral MP, Tena MT. 2012. Determination of perfluorocompounds in popcorn packaging by pressurised liquid extraction and ultra-performance liquid chromatography-tandem mass spectrometry. Talanta. 101:104–109. doi: 10.1016/j.talanta.2012.09.007.
   PubMed Web of Science ®Google Scholar
• Moreta C, Tena MT. 2013. Fast determination of perfluorocompounds in packaging by focused ultrasound solid-liquid extraction and liquid chromatography coupled to quadrupole-time of flight mass spectrometry. J Chromatogr A. 1302:88–94. doi: 10.1016/j.chroma.2013.06.024.
   PubMed Web of Science ®Google Scholar
• Nxumalo TN, Akhdhar A, Müller V, Al Zbedy A, Raab A, Krupp EM, Jovanovic M, Leitner E, Kindness A, Feldmann J. 2023. Determination of total extractable organofluorine (EOF). In Food contact materials and targeted and non-targeted analysis of PFAS using LC-MS/MS and LC-HRMS simultaneously coupled to CPMS/MS. Food Additives & Contaminants: Part A. Under review.
   Google Scholar
• Ogunbiyi OD, Ajiboye TO, Omotola EO, Oladoye PO, Olanrewaju CA, Quinete N. 2023. Analytical approaches for screening of per- and poly fluoroalkyl substances in food items: a review of recent advances and improvements. Environ Pollut. 329:121705. https://www.sciencedirect.com/science/article/pii/S0269749123007078. doi: 10.1016/j.envpol.2023.121705.
   PubMed Web of Science ®Google Scholar
• Ramírez Carnero A, Lestido-Cardama A, Vazquez Loureiro P, Barbosa-Pereira L, Rodríguez Bernaldo de Quirós A, Sendón R. 2021. Presence of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in food contact materials (FCM) and its migration to food. Foods. 10(7):1443. https://chemtrust.org/wp-content/uploads/PFASreport_FCM_May2021.pdf. doi: 10.3390/foods10071443.
   PubMed Web of Science ®Google Scholar
• Ritter EE, Dickinson ME, Harron JP, Lunderberg DM, DeYoung PA, Robel AE, Field JA, Peaslee GF. 2017. PIGE as a screening tool for per- and polyfluorinated substances in papers and textiles. Nucl Instrum Methods Phys Res Sec B. 407:47–54. https://www.sciencedirect.com/science/article/pii/S0168583X1730633X. doi: 10.1016/j.nimb.2017.05.052.
   Web of Science ®Google Scholar
• Ruan T, Lin Y, Jiang G. 2017. Progress on analytical methods and environmental behavior of emerging per- and polyfluoroalkyl substances. Chin Sci Bull. 62(24):2724–2733. doi: 10.1360/N972017-00223.
   Google Scholar
• Sapozhnikova Y, Taylor RB, Bedi M, Ng C. 2023. Assessing per- and polyfluoroalkyl substances in globally sourced food packaging. Chemosphere. 337:139381. https://www.sciencedirect.com/science/article/pii/S004565352301648X. doi: 10.1016/j.chemosphere.2023.139381.
   PubMedGoogle Scholar
• Schröder T, Müller V, Preihs M, Borovička J, Gonzalez de Vega R, Kindness A, Feldmann J. 2024. Fluorine mass balance analysis in wild boar organs from the Bohemian Forest National Park. Sci Total Environ. 922:171187. https://www.sciencedirect.com/science/article/pii/S0048969724013263. doi: 10.1016/j.scitotenv.2024.171187.
   PubMedGoogle Scholar
• Sznajder-Katarzyńska K, Surma M, Wiczkowski W, Cieślik E. 2019. The perfluoroalkyl substance (PFAS) contamination level in milk and milk products in Poland. Int Dairy J. 96:73–84. https://www.sciencedirect.com/science/article/pii/S0958694619301037. doi: 10.1016/j.idairyj.2019.04.008.
   Web of Science ®Google Scholar
• The Council of Europe. 2009. Paper and board materials and articles intended to come into contact with foodstuffs. https://rm.coe.int/16804e4794.
   Google Scholar
• Trier DX, Taxvig C, Rosenmai AK, Pedersen GA. 2018. PFAS in paper and board for food contact: options for risk management of poly- and perfluorinated substances. Copenhagen K: Nordic Council of Ministers (TemaNord).
   Google Scholar
• Valsecchi S, Babut M, Mazzoni M, Pascariello S, Ferrario C, de FB, Bettinetti R, Veyrand B, Marchand P, Polesello S. 2021. Per- and polyfluoroalkyl substances (PFAS) in fish from European lakes: current contamination status, sources, and perspectives for monitoring. Environ Toxicol Chem. 40(3):658–676. doi: 10.1002/etc.4815.
   PubMed Web of Science ®Google Scholar
• Wang Z, Cousins IT, Scheringer M, Hungerbühler K. 2013. Fluorinated alternatives to long-chain perfluoroalkyl carboxylic acids (PFCAs), perfluoroalkane sulfonic acids (PFSAs) and their potential precursors. Environ Int. 60:242–248. doi: 10.1016/j.envint.2013.08.021.
   PubMed Web of Science ®Google Scholar
• Yuan G, Peng H, Huang C, Hu J. 2016. Ubiquitous occurrence of fluorotelomer alcohols in eco-friendly paper-made food-contact materials and their implication for human exposure. Environ Sci Technol. 50(2):942–950. doi: 10.1021/acs.est.5b03806.
   PubMed Web of Science ®Google Scholar
• Zabaleta I, Bizkarguenaga E, Bilbao D, Etxebarria N, Prieto A, Zuloaga O. 2016. Fast and simple determination of perfluorinated compounds and their potential precursors in different packaging materials. Talanta. 152:353–363. doi: 10.1016/j.talanta.2016.02.022.
   PubMed Web of Science ®Google Scholar
• Zabaleta I, Blanco-Zubiaguirre L, Baharli EN, Olivares M, Prieto A, Zuloaga O, Elizalde MP. 2020. Occurrence of per- and polyfluorinated compounds in paper and board packaging materials and migration to food simulants and foodstuffs. Food Chem. 321:126746. doi: 10.1016/j.foodchem.2020.126746.
   PubMed Web of Science ®Google Scholar
• Zabaleta I, Negreira N, Bizkarguenaga E, Prieto A, Covaci A, Zuloaga O. 2017. Screening and identification of per- and polyfluoroalkyl substances in microwave popcorn bags. Food Chem. 230:497–506. doi: 10.1016/j.foodchem.2017.03.074.
   PubMed Web of Science ®Google Scholar
• Zafeiraki E, Costopoulou D, Vassiliadou I, Bakeas E, Leondiadis L. 2014. Determination of perfluorinated compounds (PFCs) in various foodstuff packaging materials used in the Greek market. Chemosphere. 94:169–176. https://www.sciencedirect.com/science/article/pii/S0045653513013623. doi: 10.1016/j.chemosphere.2013.09.092.
   PubMed Web of Science ®Google Scholar