Polyethylenimine-based nanocarriers in co-delivery of drug and gene: a developing horizon

References

• Yue J, Wu J, Liu D, et al. BMP2 gene delivery to bone mesenchymal stem cell by chitosan-g-PEI nonviral vector. Nanoscale Res Lett. 2015;10:1.
   PubMed Web of Science ®Google Scholar
• Cross D, Burmester JK. Gene therapy for cancer treatment: past, present and future. Clin Med Res. 2006;4(3):218–14.
   PubMedGoogle Scholar
• Wirth T, Ylä-Herttuala S. Gene therapy used in cancer treatment. Biomedicines. 2014;2(2):149–162.
   PubMedGoogle Scholar
• Nayerossadat N, Maedeh T, Ali PA. Viral and nonviral delivery systems for gene delivery. Adv Biomed Res. 2012;1:27.
   PubMedGoogle Scholar
• Zhang X, Zhang J, Quan G, et al. The serum-resistant transfection evaluation and long-term stability of gene delivery dry powder based on mesoporous silica nanoparticles and polyethyleneimine by freezing-drying. AAPS PharmSciTech. 2017;18(5):1536–1543.
   PubMed Web of Science ®Google Scholar
• Mokhtarzadeh A, Parhiz H, Hashemi M, et al. P53-derived peptides conjugation to PEI: an approach to producing versatile and highly efficient targeted gene delivery carriers into cancer cells. Expert Opin Drug Deliv. 2016;13(4):477–491.
   PubMed Web of Science ®Google Scholar
• Guo Z, Kong Z, Wei Y, et al. Effects of gene carrier polyethyleneimines on the structure and binding capability of bovine serum albumin. Spectrochim Acta A Mol Biomol Spectrosc. 2017;173:783–791.
   PubMed Web of Science ®Google Scholar
• Keles E, Song Y, Du D, et al. Recent progress in nanomaterials for gene delivery applications. Biomater Sci. 2016;4(9):1291–1309.
   PubMed Web of Science ®Google Scholar
• Shi S, Shi K, Tan L, et al. The use of cationic MPEG-PCL-g-PEI micelles for co-delivery of Msurvivin T34A gene and doxorubicin. Biomaterials. 2014;35(15):4536–4547.
   Web of Science ®Google Scholar
• Zhao X, Cui H, Chen W, et al. Morphology, structure and function characterization of PEI modified magnetic nanoparticles gene delivery system. PLoS One. 2014;9(6):98919.
   Web of Science ®Google Scholar
• Zhang T, Xue X, He D, et al. A prostate cancer-targeted polyarginine-disulfide linked PEI nanocarrier for delivery of microRNA. Cancer Lett. 2015;365(2):156–165.
   PubMed Web of Science ®Google Scholar
• Abebe DG, Kandil R, Kraus T, et al. Three-layered biodegradable micelles prepared by two-step self-assembly of PLA-PEI-PLA and PLA-PEG-PLA triblock copolymers as efficient gene delivery system. Macromol Biosci. 2015;15(5):698–711.
   Web of Science ®Google Scholar
• Feng G, Liu L, Gong Q, et al. Research progress of in vivo nucleic acid delivery with poly (ethylenimine). Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014;28(12):1544–1550.
   Google Scholar
• Chen Z, Krishnamachary B, Bhujwalla ZM. Degradable dextran nanopolymer as a carrier for choline kinase (ChoK) siRNA cancer therapy. Nanomaterials (Basel). 2016;6(2):34.
   Google Scholar
• Godbey WT, Wu KK, Mikos AG. Poly (ethylenimine) and its role in gene delivery. J Control Release. 1999;60(2):149–160.
   Web of Science ®Google Scholar
• Lai WF, Green DW, Jung HS. Linear poly(ethylenimine) cross-linked by methyl-beta-cyclodextrin for gene delivery. Curr Gene Ther. 2014;14(4):258–268.
   Web of Science ®Google Scholar
• Uta L, Breunig M, Blunk T, et al. Polyethylenimine-based non-viral gene delivery systems. Eur J Pharm Biopharm. 2005;60(2):247–266.
   Web of Science ®Google Scholar
• Lungu CN, Diudea MV, Putz MV, et al. Linear and branched PEIs (polyethylenimines) and their property space. Int J Mol Sci. 2016;17(4):555.
   PubMed Web of Science ®Google Scholar
• Utsuno K, Kono H, Tanaka E, et al. Low molecular weight branched PEI binding to linear DNA. Chem Pharm Bull (Tokyo). 2016;64(10):1484–1491.
   Web of Science ®Google Scholar
• Goyal R, Bansal R, Gandhi RP, et al. Copolymers of covalently crosslinked linear and branched polyethylenimines as efficient nucleic acid carriers. J Biomed Nanotechnol. 2014;10(11):3269–3279.
   Web of Science ®Google Scholar
• DeLuca JL, Hickey DP, Bamper DA, et al. Layer-by-layer assembly of ferrocene-modified linear polyethylenimine redox polymer films. Chemphyschem. 2013;14(10):2149–2158.
   Web of Science ®Google Scholar
• Koo H, Jin GW, Kang H, et al. Biodegradable branched poly(ethylenimine sulfide) for gene delivery. Biomaterials. 2010;31(5):988–997.
   Web of Science ®Google Scholar
• Shih Y, Venault A, Zwitterionic-Shielded A. Carrier with pH-modulated reversible self-assembly for gene transfection. Langmuir. 2017;33(8):1914–1926.
   Web of Science ®Google Scholar
• Wang T, Chen Q, Lu H, et al. Shedding PEG palisade by temporal photostimulation and intracellular reducing milieu for facilitated intracellular trafficking and DNA release. Bioconjug Chem. 2016;27(8):1949–1957.
   Web of Science ®Google Scholar
• Larsen AK, Malinska D, Koszela-Piotrowska I, et al. Polyethylenimine-mediated impairment of mitochondrial membrane potential, respiration and membrane integrity: implications for nucleic acid delivery and gene therapy. Mitochondrion. 2012;12(1):162–168.
   PubMed Web of Science ®Google Scholar
• Lazarus GG, Singh M. In vitro cytotoxic activity and transfection efficiency of polyethyleneimine functionalized gold nanoparticles. Colloids Surf B Biointerfaces. 2016;145:906–911.
   Web of Science ®Google Scholar
• Meleshko AN, Petrovskaya NA, Savelyeva N, et al. Phase I clinical trial of idiotypic DNA vaccine administered as a complex with polyethylenimine to patients with B-cell lymphoma. Hum Vaccin Immunother. 2017;13(6):1–6.
   Web of Science ®Google Scholar
• Pishavar E, Shafiei M, Mehri S, et al. The effects of polyethylenimine/DNA nanoparticle on transcript levels of apoptosis-related genes. J Phys Chem B. 2017;40(4):1–4.
   Google Scholar
• Santos JL, Ren Y, Vandermark J, et al. Continuous production of discrete plasmid DNA-polycation nanoparticles using flash nanocomplexation. Small. 2016;12(45):6214–6222.
   Web of Science ®Google Scholar
• Curtis KA, Miller D, Millard P, et al. Unusual salt and pH induced changes in polyethylenimine solutions. PLoS One. 2016;11(9):e0158147.
   Web of Science ®Google Scholar
• Ziebarth JD, Kennetz DR, Walker NJ, et al. Structural comparisons of PEI/DNA and PEI/siRNA complexes revealed with molecular dynamics simulations. J Phys Chem B. 2017;121(8):1941–1952.
   Web of Science ®Google Scholar
• Guo A, Wang Y, Xu S, et al. Preparation and evaluation of pH-responsive charge-convertible ternary complex FA-PEI-CCA/PEI/DNA with low cytotoxicity and efficient gene delivery. Colloids Surf B Biointerfaces. 2017;152:58–67.
   PubMed Web of Science ®Google Scholar
• Dempsey C, Lee I, Cowan KR, et al. Coating barium titanate nanoparticles with polyethylenimine improves cellular uptake and allows for coupled imaging and gene delivery. Colloids Surf B Biointerfaces. 2013;112:108–112.
   PubMed Web of Science ®Google Scholar
• Wang C, Sun G, Wang Y, et al. Bacterial magnetic particles improve testes-mediated transgene efficiency in mice. Drug Deliv. 2017;24(1):651–659.
   PubMed Web of Science ®Google Scholar
• Park JS, Yi SW, Kim HJ, et al. Construction of PLGA nanoparticles coated with polycistronic SOX5, SOX6, and SOX9 genes for chondrogenesis of human mesenchymal stem cells. ACS Appl Mater Interfaces. 2017;9(2):1361–1372.
   Web of Science ®Google Scholar
• Guan X, Guo Z, Wang T, et al. A pH-responsive detachable PEG shielding strategy for gene delivery system in cancer therapy. Biomacromolecules. 2017;18(4):1342–1349.
   PubMed Web of Science ®Google Scholar
• Yang W, Bai Y, Wang X, et al. Attaching biosynthesized bacterial magnetic particles to polyethylenimine enhances gene delivery into mammalian cells. J Biomed Nanotechnol. 2016;12(4):789–799.
   Web of Science ®Google Scholar
• Kichler A, Leborgne C, Danos O. Dilution of reporter gene with stuffer DNA does not alter the transfection efficiency of polyethylenimines. J Gene Med. 2005;7(11):1459–1467.
   Web of Science ®Google Scholar
• Akinc A, Thomas M, Klibanov AM, et al. Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med. 2005;7(5):657–663.
   PubMed Web of Science ®Google Scholar
• Ren Y, Jiang X, Pan D, et al. Charge density and molecular weight of polyphosphoramidate gene carrier are key parameters influencing its DNA compaction ability and transfection efficiency. Biomacromolecules. 2010;11(12):3432–3439.
   Web of Science ®Google Scholar
• Forcato DO, Fili AE, Alustiza FE, et al. Transfection of bovine fetal fibroblast with polyethylenimine (PEI) nanoparticles: effect of particle size and presence of fetal bovine serum on transgene delivery and cytotoxicity. Cytotechnology. 2017;69(655):1–11.
   Google Scholar
• Mintzer MA, Simanek EE. Nonviral vectors for gene delivery. Chem Rev. 2009;109(2):259–302.
   PubMed Web of Science ®Google Scholar
• Derouazi M, Girard P, Van Tilborgh F, et al. Serum-free large-scale transient transfection of CHO cells. Biotechnol Bioeng. 2004;87(4):537–545.
   Web of Science ®Google Scholar
• Sang Y, Xie K, Mu Y, et al. Salt ions and related parameters affect PEI-DNA particle size and transfection efficiency in Chinese hamster ovary cells. Cytotechnology. 2015;67(1):67–74.
   Web of Science ®Google Scholar
• Sharma VK, Thomas M, Klibanov AM. Mechanistic studies on aggregation of polyethylenimine-DNA complexes and its prevention. Biotechnol Bioeng. 2005;90(5):614–620.
   Web of Science ®Google Scholar
• Zauner W, Farrow NA, Haines AM. In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density. J Control Release. 2001;71(1):39–51.
   PubMed Web of Science ®Google Scholar
• Grosse S, Aron Y, Honoré I, et al. Lactosylated polyethylenimine for gene transfer into airway epithelial cells: role of the sugar moiety in cell delivery and intracellular trafficking of the complexes. J Gene Med. 2004;6(3):345–356.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Fernandez T, Sathy BN, Hobbs C, et al. Mesenchymal stem cell fate following non-viral gene transfection strongly depends on the choice of delivery vector. Acta Biomater. 2017;55:226–238.
   PubMed Web of Science ®Google Scholar
• Ye X, Li S, Chen X, et al. Polyethylenimine/silk fibroin multilayers deposited nanofibrics for cell culture. Int J Biol Macromol. 2017;94:492–499.
   Web of Science ®Google Scholar
• Gurumurthy B, Bierdeman PC, Janorkar AV. Spheroid model for functional osteogenic evaluation of human adipose derived stem cells. J Biomed Mater Res A. 2017;105(4):1230–1236.
   PubMed Web of Science ®Google Scholar
• Kumar S, Raj S, Sarkar K, et al. Engineering a multi-biofunctional composite using poly(ethylenimine) decorated graphene oxide for bone tissue regeneration. Nanoscale. 2016;8(12):6820–6836.
   PubMed Web of Science ®Google Scholar
• Dongjie S, Wu H, Shen F, et al. Carbon dioxide-modified polyethylenimine as a novel gene delivery vector and its in vitro validation. J Biomater Appl. 2017;31(9):1257–1266.
   Web of Science ®Google Scholar
• Liu S, Zhou D, Yang J, et al. Bioreducible Zinc(II)-coordinative polyethylenimine with low molecular weight for robust gene delivery of primary and stem cells. J Am Chem Soc. 2017;139(14):5102–5109.
   Google Scholar
• Pang ST, Lin FW, Chuang CK, et al. Co-delivery of docetaxel and p44/42 MAPK siRNA using PSMA antibody-conjugated BSA-PEI layer-by-layer nanoparticles for prostate cancer target therapy. Macromol Biosci. 2017;17(5):1600421.
   Web of Science ®Google Scholar
• Oroojalian F, Rezayan AH, Shier WT, et al. Megalin-targeted enhanced transfection efficiency in cultured human HK-2 renal tubular proximal cells using aminoglycoside-carboxyalkyl- polyethylenimine -containing nanoplexes. Int J Pharm. 2017;523(1):102–120.
   Web of Science ®Google Scholar
• Li Y, Guo M, Lin Z, et al. Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis. Int J Nanomed. 2016;11:6693–6702.
   PubMed Web of Science ®Google Scholar
• Dong S, Zhou X, Yang J. TAT modified and lipid - PEI hybrid nanoparticles for co-delivery of docetaxel and pDNA. Biomed Pharmacother. 2016;84:954–961.
   PubMed Web of Science ®Google Scholar
• Pandey PC, Pandey G, Narayan RJ. Polyethylenimine-mediated synthetic insertion of gold nanoparticles into mesoporous silica nanoparticles for drug loading and biocatalysis. Biointerphases. 2017;12(1):011005.
   Web of Science ®Google Scholar
• Wang H, Li Y, Zhang M, et al. Redox-activatable ATP-depleting micelles with dual modulation characteristics for multidrug-resistant cancer therapy. Adv Healthc Mater. 2017;6(8):1601293.
   Web of Science ®Google Scholar
• Yang B, Ni X, Chen L, et al. Honokiol-loaded polymeric nanoparticles: an active targeting drug delivery system for the treatment of nasopharyngeal carcinoma. Drug Deliv. 2017;24(1):660–669.
   PubMed Web of Science ®Google Scholar
• Wang Q, Jiang H, Li Y, et al. Targeting NF-kB signaling with polymeric hybrid micelles that co-deliver siRNA and dexamethasone for arthritis therapy. Biomaterials. 2017;122:10–22.
   PubMed Web of Science ®Google Scholar
• Chien Y, Chang YL, Li HY, et al. Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model. Acta Biomater. 2015;13:228–244.
   Web of Science ®Google Scholar
• Wu Y, Zhang Y, Zhang W, et al. Reversing of multidrug resistance breast cancer by co-delivery of P-gp siRNA and doxorubicin via folic acid-modified core-shell nanomicelles. Colloids Surf B Biointerfaces. 2016;138:60–69.
   PubMed Web of Science ®Google Scholar
• Chen L, Ji F, Bao Y, et al. Biocompatible cationic pullulan-g-desoxycholic acid-g-PEI micelles used to co-deliver drug and gene for cancer therapy. Mater Sci Eng C Mater Biol Appl. 2017;70:418–429.
   PubMed Web of Science ®Google Scholar
• Wang S, Zhang J, Wang Y, et al. Hyaluronic acid-coated PEI-PLGA nanoparticles mediated co-delivery of doxorubicin and miR-542-3p for triple negative breast cancer therapy. Nanomedicine. 2016;12(2):411–420.
   PubMed Web of Science ®Google Scholar
• Jia H, Chen S, Zhuo R, et al. Polymeric prodrug for bio-controllable gene and drug co-delivery. Sci China Chem. 2016;59(11):1397–1404.
   Web of Science ®Google Scholar
• Chen W, Meng F, Cheng R, et al. Advanced drug and gene delivery systems based on functional biodegradable polycarbonates and copolymers. J Control Release. 2014;190:398–414.
   Web of Science ®Google Scholar
• Liu S, Huang W, Jin MJ, et al. Inhibition of murine breast cancer growth and metastasis by survivin-targeted siRNA using disulfide cross-linked linear PEI. Eur J Pharm Sci. 2016;82:171–182.
   PubMed Web of Science ®Google Scholar
• Yu K, Zhao J, Yu C, et al. Role of four different kinds of polyethylenimines (PEIs) in preparation of polymeric lipid nanoparticles and their anticancer activity study. J Cancer. 2016;7(7):872–882.
   PubMed Web of Science ®Google Scholar
• Fang G, Zeng F, Yu C, et al. Low molecular weight PEIs modified by hydrazone-based crosslinker and betaine as improved gene carriers. Colloids Surf B Biointerfaces. 2014;122:472–481.
   PubMed Web of Science ®Google Scholar
• Cho WY, Hong SH, Singh B, et al. Suppression of tumor growth in lung cancer xenograft model mice by poly(sorbitol-co-PEI)-mediated delivery of osteopontin siRNA. Eur J Pharm Biopharm. 2015;94:450–462.
   PubMed Web of Science ®Google Scholar
• Lee JL, Lo CW, Inserra C, et al. Ultrasound enhanced PEI-mediated gene delivery through increasing the intracellular calcium level and PKC-delta protein expression. Pharm Res. 2014;31(9):2354–2366.
   PubMed Web of Science ®Google Scholar
• Kim YH, Park JH, Lee M, et al. Polyethylenimine with acid-labile linkages as a biodegradable gene carrier. J Control Release. 2005;103(1):209–219.
   PubMed Web of Science ®Google Scholar
• Yu K, Zhao J, Zhang Z, et al. Enhanced delivery of Paclitaxel using electrostatically-conjugated herceptin-bearing PEI/PLGA nanoparticles against HER-positive breast cancer cells. Int J Pharm. 2016;497(1–2):78–87.
   PubMed Web of Science ®Google Scholar
• Gao S, Tian H, Guo Y, et al. miRNA oligonucleotide and sponge for miRNA-21 inhibition mediated by PEI-PLL in breast cancer therapy. Acta Biomater. 2015;25:184–193.
   PubMed Web of Science ®Google Scholar
• Muthiah M, Che HL, Kalash S, et al. Formulation of glutathione responsive anti-proliferative nanoparticles from thiolated Akt1 siRNA and disulfide-crosslinked PEI for efficient anti-cancer gene therapy. Colloids Surf B Biointerfaces. 2015;126:322–327.
   PubMed Web of Science ®Google Scholar
• Liang G, Li Y, Feng W, et al. Polyethyleneimine-coated quantum dots for miRNA delivery and its enhanced suppression in HepG2 cells. Int J Nanomed. 2016;11:6079–6088.
   Web of Science ®Google Scholar
• Zhang L, Yu M, Wang J, et al. Low molecular weight PEI-based vectors via acid-labile ortho ester linkage for improved gene delivery. Macromol Biosci. 2016;16(8):1175–1187.
   PubMed Web of Science ®Google Scholar
• Luten J, van Nostrum CF, De Smedt SC, et al. Biodegradable polymers as non-viral carriers for plasmid DNA delivery. J Control Release. 2008;126(2):97–110.
   PubMed Web of Science ®Google Scholar
• Qiu S, Granet R, Mbakidi JP, et al. Delivery of tanshinone IIA and alpha-mangostin from gold/PEI/cyclodextrin nanoparticle platform designed for prostate cancer chemotherapy. Bioorg Med Chem Lett. 2016;26(10):2503–2506.
   PubMed Web of Science ®Google Scholar
• Ravanshad R, Karimi Zadeh A, Amani AM, et al. Application of nanoparticles in cancer detection by Raman scattering based techniques. Nano Reviews & Experiments.2018;9(1):1373551.
   Google Scholar
• Mousavi S, Esmaeili H, Arjmand O, et al. Biodegradation study of nanocomposites of phenol novolac epoxy/unsaturated polyester resin/egg shell nanoparticles using natural polymers. Journal of Materials. 2015; 2015:1–6.
   Google Scholar
• Mousavi SM, Hashemi SA, Jahandideh S, et al. Modification of Phenol Novolac Epoxy Resin and Unsaturated Polyester Using Sasobit and Silica Nanoparticles. Polymers from Renewable Resources. 2017; 8(3): 117–131.
   Google Scholar
• Mousavi S, Arjmand O, Hashemi S, et al. Modification of the Epoxy Resin Mechanical and Thermal Properties with Silicon Acrylate and Montmorillonite Nanoparticles. Polymers from Renewable Resources. 2016; 7(3):101–113.
   Google Scholar
• Amani AM, Hashemi SA, Mousavi SM, et al. Electric Field Induced Alignment of Carbon Nanotubes: Methodology and Outcomes. Carbon Nanotubes - Recent Progress, London: IntechOpen; 2018. 71-88.
   Google Scholar
• Hashemi SA, Mousavi SM, Effect of bubble based degradation on the physical properties of Single Wall Carbon Nanotube/Epoxy Resin composite and new approach in bubbles reduction. Composites Part A.2016; 90:457–469.
   Web of Science ®Google Scholar
• Hashemi SA, Mousavi SM, Arjmand M, et al. Electrified single‐walled carbon nanotube/epoxy nanocomposite via vacuum shock technique: Effect of alignment on electrical conductivity and electromagnetic interference shielding. Polym Compos. 2018; 39(2):1139–1148.
   Google Scholar
• Mousavi SM, Hashemi SA, Amani AM, et al. Polyethylene Terephthalate/Acryl Butadiene Styrene Copolymer Incorporated with Oak Shell, Potassium Sorbate and Egg Shell Nanoparticles for Food Packaging Applications: Control of Bacteria Growth, Physical and Mechanical Properties. Polymers from Renewable Resources. 2017; 8(4): 177–196.
   Google Scholar
• Goudarzian N, Hashemi SA, Mirjalili M, Unsaturated Polyester Resins Modified With Cresol Novolac Epoxy and Silica Nanoparticles: Processing and Mechanical Properties. Int J Chem Pet Sci. 2016; 5(1):13–26.
   Google Scholar
• Hashemi SA, Mousavi SM, Faghihi R, et al. Lead oxide-decorated graphene oxide/epoxy composite towards X-ray radiation shielding. Rad Phy Chem. 2018; 146:77–85.
   Web of Science ®Google Scholar
• Mousavi S, Aghili A, Hashemi S, et al. Improved morphology and properties of nanocomposites, linear low density polyethylene, ethylene-co-vinyl acetate and nano clay particles by electron beam. Polymers from Renewable Resources. 2016;7(4):135.
   Google Scholar