Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India

References

• Kumar N, Tripathi BN. A serious skin virus epidemic sweeping through the Indian subcontinent is a threat to the livelihood of farmers. Virulence. 2022;13:1943–22.
   PubMed Web of Science ®Google Scholar
• CABI. Lumpy skin Disease; 2019. Available from: https://wwwcabiorg/isc/datasheet/76780.
   Google Scholar
• Tuppurainen ES, Oura CA. Review: lumpy skin disease: an emerging threat to Europe, the Middle East and Asia. Transbound Emerg Dis. 2012;59:40–48.
   PubMed Web of Science ®Google Scholar
• Yeruham I, Nir O, Braverman Y, et al. Spread of lumpy skin disease in Israeli dairy herds. Vet Rec. 1995;137:91–93.
   PubMed Web of Science ®Google Scholar
• Kumar N, Chander Y, Kumar R, et al. Isolation and characterization of lumpy skin disease virus from cattle in India. PLoS ONE. 2021;16:e0241022.
   PubMed Web of Science ®Google Scholar
• Casal J, Allepuz A, Miteva A, et al. Economic cost of lumpy skin disease outbreaks in three Balkan countries: Albania, Bulgaria and the Former Yugoslav Republic of Macedonia (2016-2017). Transbound Emerg Dis. 2018;65:1680–1688.
   PubMed Web of Science ®Google Scholar
• Shagun. Lump Skin Disease has created a livehood crisis for India’s small dairy farmers. DownToearth. September 30 2022. https://www.downtoearth.org.in/news/economy/ground-report-lumpy-skin-disease-has-created-a-livelihood-crisis-for-india-s-small-dairy-farmers-85245
   Google Scholar
• Lojkic I, Simic I, Kresic N, et al. Complete genome sequence of a lumpy skin disease virus strain isolated from the skin of a vaccinated animal. Genome Announc. 2018;6:6.
   Google Scholar
• Abutarbush SM, Tuppurainen ESM. Serological and clinical evaluation of the Yugoslavian RM65 sheep pox strain vaccine use in cattle against lumpy skin disease. Transbound Emerg Dis. 2018;65:1657–1663.
   PubMed Web of Science ®Google Scholar
• Tuppurainen ESM, Venter EH, Shisler JL, et al. Review: capripoxvirus diseases: current status and opportunities for control. Transbound Emerg Dis. 2017;64:729–745.
   PubMed Web of Science ®Google Scholar
• Teffera M, Babiuk S. Potential of using Capripoxvirus vectored vaccines against arboviruses in sheep, goats, and cattle. Front Vet Sci. 2019;6:450.
   PubMed Web of Science ®Google Scholar
• Kitching RP. Vaccines for lumpy skin disease, sheep pox and goat pox. Dev Biol (Basel). 2003;114:161–167.
   PubMedGoogle Scholar
• Tuppurainen ES, Pearson CR, Bachanek-Bankowska K, et al. Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus. Antiviral Res. 2014;109:1–6.
   PubMed Web of Science ®Google Scholar
• Annual Report. Guidelines and advisory on lumpy skin disease virus. Annual Report of Department of Animal Husbandry, Dairying and Fisheries, Ministry of Animal Husbandry and Dairying, Government of India; 2022. p. 89.
   Google Scholar
• Gaber A, Rouby S, Elsaied A, et al. Assessment of heterologous lumpy skin disease vaccine-induced immunity in pregnant cattle vaccinated at different times of gestation period and their influence on maternally derived antibodies. Vet Immunol Immunopathol. 2022;244:110380.
   PubMed Web of Science ®Google Scholar
• Hamdi J, Boumart Z, Daouam S, et al. Development and evaluation of an inactivated lumpy skin disease vaccine for cattle. Vet Microbiol. 2020;245:108689.
   PubMed Web of Science ®Google Scholar
• Brenner J, Bellaiche M, Gross E, et al. Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: statutory challenge. Vaccine. 2009;27:1500–1503.
   PubMed Web of Science ®Google Scholar
• Abutarbush SM. Efficacy of vaccination against lumpy skin disease in Jordanian cattle. Vet Rec. 2014;175:302.
   PubMed Web of Science ®Google Scholar
• Sevik M, Dogan M. Epidemiological and molecular studies on lumpy skin disease outbreaks in Turkey during 2014-2015. Transbound Emerg Dis. 2017;64:1268–1279.
   PubMed Web of Science ®Google Scholar
• Rao TV, Bandyopadhyay SK. A comprehensive review of goat pox and sheep pox and their diagnosis. Anim Health Res Rev. 2000;1:127–136.
   PubMedGoogle Scholar
• Abd-Elfatah EB, El-Mekkawi MF, Aboul-Soud EA. Capripoxviruses of small ruminants: control and evaluating the future update efficacy of a current vaccine in Egypt. Advances in Environmental Biology. 2018;12:11–16.
   Google Scholar
• Ben-Gera J, Klement E, Khinich E, et al. Comparison of the efficacy of Neethling lumpy skin disease virus and x10rm65 sheep-pox live attenuated vaccines for the prevention of lumpy skin disease - the results of a randomized controlled field study. Vaccine. 2015;33:4837–4842.
   PubMed Web of Science ®Google Scholar
• Kumar N, Wadhwa A, Chaubey KK, et al. Isolation and phylogenetic analysis of an orf virus from sheep in Makhdoom, India. Virus Genes. 2014;48:312–319.
   PubMed Web of Science ®Google Scholar
• Khandelwal N, Chander Y, Rawat KD, et al. Emetine inhibits replication of RNA and DNA viruses without generating drug-resistant virus variants. Antiviral Res. 2017;144:196–204.
   PubMed Web of Science ®Google Scholar
• Alexander S, Olga B, Svetlana K, et al. A real-time PCR screening assay for the universal detection of lumpy skin disease virus DNA. BMC Res Notes. 2019;12:371.
   PubMed Web of Science ®Google Scholar
• Agianniotaki EI, Chaintoutis SC, Haegeman A, et al. Development and validation of a TaqMan probe-based real-time PCR method for the differentiation of wild type lumpy skin disease virus from vaccine virus strains. J Virol Methods. 2017;249:48–57.
   PubMed Web of Science ®Google Scholar
• WOAH. Manual of diagnostic tests and vaccines for terrestrial animals 2021. Lumpy Skin Disease, Chapter 3.4.12. 2021 [cited 2022 Dec 8]. Available from: https://www.woah.org/fileadmin/Home/eng/Health_standards/tahm/3.04.12_LSD.pdf.
   Google Scholar
• Sanchez-Sampedro L, Perdiguero B, Mejias-Perez E, et al. The evolution of poxvirus vaccines. Viruses. 2015;7:1726–1803.
   PubMed Web of Science ®Google Scholar
• Biswas S, Noyce RS, Babiuk LA, et al. Extended sequencing of vaccine and wild-type capripoxvirus isolates provides insights into genes modulating virulence and host range. Transbound Emerg Dis. 2020;67:80–97.
   PubMed Web of Science ®Google Scholar
• Tuppurainen E, Dietze K, Wolff J, et al. Review: vaccines and vaccination against lumpy skin disease. Vaccines (Basel). 2021;9:1136.
   PubMedGoogle Scholar
• Woods JA. Lumpy skin disease–a review. Trop Anim Health Prod. 1988;20:11–17.
   PubMed Web of Science ®Google Scholar
• Hamdi J, Munyanduki H, Omari Tadlaoui K, et al. Capripoxvirus infections in Ruminants: a review. Microorganisms. 2021;9:902.
   PubMed Web of Science ®Google Scholar
• Babiuk S, Bowden TR, Parkyn G, et al. Quantification of lumpy skin disease virus following experimental infection in cattle. Transbound Emerg Dis. 2008;55:299–307.
   PubMed Web of Science ®Google Scholar
• Hamdi J, Bamouh Z, Jazouli M, et al. Experimental evaluation of the cross-protection between Sheeppox and bovine Lumpy skin vaccines. Sci Rep. 2020;10:8888.
   PubMed Web of Science ®Google Scholar
• Mikhael C, Ibrahim M, Saad M. Efficacy of alternative vaccination with attenuated sheep pox and inactivated lumpy skin disease vaccines against lumpy skin disease. Suez Canal Vet Med J. 2016;21:125–142.
   Google Scholar
• Chervyakova OV, Sultankulova KT, Nissanova RK, et al. Lumpy skin disease virus: approaches to attenuation for vaccine development. Eurasian J Appl Biotechnol. 2019;1:3–12.
   Google Scholar
• Sudhakar SB, Mishra N, Kalaiyarasu S, et al. Lumpy skin disease (LSD) outbreaks in cattle in Odisha state, India in August 2019: epidemiological features and molecular studies. Transbound Emerg Dis. 2020;67:2408–2422.
   PubMed Web of Science ®Google Scholar
• Gari G, Abie G, Gizaw D, et al. Evaluation of the safety, immunogenicity and efficacy of three capripoxvirus vaccine strains against lumpy skin disease virus. Vaccine. 2015;33:3256–3261.
   PubMed Web of Science ®Google Scholar
• Prozesky L, Barnard BJ. A study of the pathology of lumpy skin disease in cattle. Onderstepoort J Vet Res. 1982;49:167–175.
   PubMed Web of Science ®Google Scholar
• Moller J, Moritz T, Schlottau K, et al. Experimental lumpy skin disease virus infection of cattle: comparison of a field strain and a vaccine strain. Arch Virol. 2019;164:2931–2941.
   PubMed Web of Science ®Google Scholar
• Sanz-Bernardo B, Haga IR, Wijesiriwardana N, et al. Lumpy skin disease is characterized by severe multifocal dermatitis with necrotizing fibrinoid vasculitis following experimental infection. Vet Pathol. 2020;57:388–396.
   PubMed Web of Science ®Google Scholar
• Haegeman A, De Leeuw I, Mostin L, et al. Comparative evaluation of lumpy skin disease virus-based live attenuated vaccines. Vaccines (Basel). 2021;9:473.
   PubMed Web of Science ®Google Scholar
• Davies FG. Lumpy skin disease of cattle: a growing problem in Africa and the Near East. World Anim Rev. 1991;68:37–42.
   Google Scholar
• Klement E, Broglia A, Antoniou S-E, et al. Neethling vaccine proved highly effective in controlling lumpy skin disease epidemics in the Balkans. Prev Vet Med. 2020;181:104595.
   PubMed Web of Science ®Google Scholar
• Lamien CE, Le Goff C, Silber R, et al. Use of the Capripoxvirus homologue of Vaccinia virus 30 kDa RNA polymerase subunit (RPO30) gene as a novel diagnostic and genotyping target: development of a classical PCR method to differentiate Goat poxvirus from Sheep poxvirus. Vet Microbiol. 2011;149:30–39.
   PubMed Web of Science ®Google Scholar
• Tulman ER, Afonso CL, Lu Z, et al. The genomes of sheeppox and goatpox viruses. J Virol. 2002;76:6054–6061.
   PubMed Web of Science ®Google Scholar
• Salib FA, Osman AH. Incidence of lumpy skin disease among Egyptian cattle in Giza Governorate, Egypt. Vet World. 2011;4:162–167.
   Google Scholar
• Ayelet G, Abate Y, Sisay T, et al. Lumpy skin disease: preliminary vaccine efficacy assessment and overview on outbreak impact in dairy cattle at Debre Zeit, central Ethiopia. Antiviral Res. 2013;98:261–265.
   PubMed Web of Science ®Google Scholar
• Tuppurainen ESM, Antoniou SE, Tsiamadis E, et al. Field observations and experiences gained from the implementation of control measures against lumpy skin disease in South-East Europe between 2015 and 2017. Prev Vet Med. 2020;181:104600.
   PubMed Web of Science ®Google Scholar
• Katsoulos PD, Chaintoutis SC, Dovas CI, et al. Investigation on the incidence of adverse reactions, viraemia and haematological changes following field immunization of cattle using a live attenuated vaccine against lumpy skin disease. Transbound Emerg Dis. 2018;65:174–185.
   PubMed Web of Science ®Google Scholar
• Abutarbush SM, Hananeh WM, Ramadan W, et al. Adverse reactions to field vaccination against lumpy skin disease in Jordan. Transbound Emerg Dis. 2016;63:e213–9.
   PubMed Web of Science ®Google Scholar
• Bedekovic T, Simic I, Kresic N, et al. Detection of lumpy skin disease virus in skin lesions, blood, nasal swabs and milk following preventive vaccination. Transbound Emerg Dis. 2018;65:491–496.
   PubMed Web of Science ®Google Scholar
• Osuagwuh UI, Bagla V, Venter EH, et al. Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection. Vaccine. 2007;25:2238–2243.
   PubMed Web of Science ®Google Scholar
• Namazi F, Khodakaram Tafti A. Lumpy skin disease, an emerging transboundary viral disease: a review. Vet Med Sci. 2021;7:888–896.
   PubMed Web of Science ®Google Scholar
• Norian R, Afzal Ahangaran N, Azadmehr A. Evaluation of humoral and cell-mediated immunity of two capripoxvirus vaccine strains against lumpy skin disease virus. Iran J Virol. 2016;10:1–11.
   Google Scholar
• Varshovi HR, Norian R, Azadmehr A, et al. Immune response characteristics of Capri pox virus vaccines following emergency vaccination of cattle against lumpy skin disease virus. Iran J Vet Sci Technol. 2017;9:33–40.
   Google Scholar
• Bhanuprakash V, Indrani BK, Hegde R, et al. A classical live attenuated vaccine for sheep pox. Trop Anim Health Prod. 2004;36:307–320.
   PubMed Web of Science ®Google Scholar
• Boumart Z, Daouam S, Belkourati I, et al. Comparative innocuity and efficacy of live and inactivated sheeppox vaccines. BMC Vet Res. 2016;12:133.
   PubMed Web of Science ®Google Scholar
• Kumar N, Sharma S, Barua S, et al. Virological and immunological outcomes of coinfections. Clin Microbiol Rev. 2018;31:31.
   Web of Science ®Google Scholar
• Khafagy HA, Saad MA, Abdelwahab MG, et al. Preparation and field evaluation of live attenuated sheep pox vaccine for protection of calves against lumpy skin disease. Benha Vet Med J. 2016;31:1–7.
   Google Scholar
• Fay PC, Wijesiriwardana N, Munyanduki H, et al. The immune response to lumpy skin disease virus in cattle is influenced by inoculation route. Front Immunol. 2022;13:6947.
   Google Scholar
• Abutarbush SM, Ababneh MM, Al Zoubi IG, et al. Lumpy skin disease in Jordan: disease emergence, clinical signs, complications and preliminary-associated economic losses. Transbound Emerg Dis. 2015;62:549–554.
   PubMed Web of Science ®Google Scholar
• Kafafy M, El Soally S, Aboul-Soud E, et al. Preparation of trivalent vaccine against lumpy skin disease using different capripox viral strain. Vet Med J (Giza). 2018;64:23–38.
   Google Scholar
• Abdallah FM, El Damaty HM, Kotb GF. Sporadic cases of lumpy skin disease among cattle in Sharkia province, Egypt: genetic characterization of lumpy skin disease virus isolates and pathological findings. Vet World. 2018;11:1150–1158.
   PubMed Web of Science ®Google Scholar
• Bamouh Z, Hamdi J, Fellahi S, et al. Investigation of post vaccination reactions of two live attenuated vaccines against lumpy skin disease of Cattle. Vaccines. 2021;9:621.
   Web of Science ®Google Scholar
• Kara PD, Afonso CL, Wallace DB, et al. Comparative sequence analysis of the South African vaccine strain and two virulent field isolates of Lumpy skin disease virus. Arch Virol. 2003;148:1335–1356.
   PubMed Web of Science ®Google Scholar
• Agianniotaki EI, Babiuk S, Katsoulos PD, et al. Colostrum transfer of neutralizing antibodies against lumpy skin disease virus from vaccinated cows to their calves. Transbound Emerg Dis. 2018;65:2043–2048.
   PubMed Web of Science ®Google Scholar
• DAHD. Lumpy skin disease, monthly report of the department of animal husbandary, Government of Rajasthan, India. 2022.
   Google Scholar