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Brief Report

Down-regulation of miR-140-3p is a cause of the interlukin-13-induced up-regulation of RhoA protein in bronchial smooth muscle cells

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Pages 1-6 | Received 27 Oct 2020, Accepted 31 Dec 2020, Published online: 11 Jan 2021

References

  • Seow CY, Schellenberg RR, Pare PD. Structural and functional changes in the airway smooth muscle of asthmatic subjects. Am J Respir Crit Care Med. 1998;158(supplement_2):S179–86.
  • Martin JG, Duguet A, Eidelman DH. The contribution of airway smooth muscle to airway narrowing and airway hyperresponsiveness in disease. Eur Respir J. 2000;16(2):349–354.
  • Sutcliffe A, Hollins F, Gomez E, et al. Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma. Am J Respir Crit Care Med. 2012;185(3):267–274.
  • Somlyo AP, Somlyo AV. Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol. 2012;522(2):177–185.
  • Chiba Y, Takada Y, Miyamoto S, et al. Augmented acetylcholine-induced, Rho-mediated Ca 2+++ sensitization of bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats. Br J Pharmacol. 1999;127(3):597–600.
  • Schaafsma D, Gosens R, Bos IS, et al. Allergic sensitization enhances the contribution of Rho-kinase to airway smooth muscle contraction. Br J Pharmacol. 2004;143(4):477–484.
  • Chiba Y, Ueno A, Shinozaki K, et al. Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice. Respir Res. 2005;6(1):4.
  • Kudo M, Melton AC, Chen C, et al. IL-17A produced by αβT cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nat Med. 2015;18(4):547–554.
  • Wei B, Shang YX, Li M, et al. Cytoskeleton changes of airway smooth muscle cells in juvenile rats with airway remodeling in asthma and the RhoA/ROCK signaling pathway mechanism. Genet Mol Res. 2014;13(1):559–569.
  • Balenga NA, Klichinsky M, Xie Z, et al. A fungal protease allergen provokes airway hyper-responsiveness in asthma. Nat Commun. 2015;6(1):6763.
  • Chiba Y, Nakazawa S, Todoroki M, et al. Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein. Am J Respir Cell Mol Biol. 2009;40(2):159–167.
  • Chiba Y, Tanabe M, Goto K, et al. Down-regulation of miR-133a contributes to up-regulation of Rhoa in bronchial smooth muscle cells. Am J Respir Crit Care Med. 2009;180(8):713–719.
  • Kudo M, Khalifeh Soltani SM, Sakuma SA, et al. Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction. Proc Natl Acad Sci USA. 2013;110(2):660–665.
  • Ambros V. The functions of animal microRNAs. Nature. 2004;431(7006):350–355.
  • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–297.
  • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215–233.
  • Wu DD, Song J, Bartel S, et al. The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach. Pharmacol Ther. 2018;182:1–14.
  • Stolzenburg LR, Harris A. The role of microRNAs in chronic respiratory disease: recent insights. Biol Chem. 2018;399:219–234.
  • Tost J. A translational perspective on epigenetics in allergic diseases. J Allergy Clin Immunol. 2018;142(3):715–726.
  • Svitich OA, Sobolev VV, Gankovskaya LV, et al. The role of regulatory RNAs (miRNAs) in asthma. Allergol Immunopathol (Madr). 2018;46(2):201–205.
  • Kuhn AR, Schlauch K, Lao R, et al. MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype. Am J Respir Cell Mol Biol. 2010;42(4):506–513.
  • Jude JA, Dileepan M, Subramanian S, et al. miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2012;303(5):L460–8.
  • Deshpande DA, Guedes AGP, Graeff R, et al. CD38/cADPR Signaling Pathway in Airway Disease: regulatory Mechanisms. Mediators Inflamm. 2018;2018:8942042.
  • Specjalski K, Jassem E. MicroRNAs: potential biomarkers and targets of therapy in allergic diseases? Arch Immunol Ther Exp. 2019;67:213–223.
  • Chiba Y, Ando Y, Fujii S, et al. Down-regulation of miR-140-3p is a cause of up-regulation of RhoA protein in bronchial smooth muscle of murine experimental asthma. Am J Respir Cell Mol Biol. 2021;64(1):138–140
  • Chiba Y, Todoroki M, Nishida Y, et al. A novel STAT6 inhibitor AS1517499 ameliorates antigen-induced bronchial hypercontractility in mice. Am J Respir Cell Mol Biol. 2009;41(5):516–524.
  • Mousavi SR, Ahmadi A, Jamalkandi SA, et al. Involvement of microRNAs in physiological and pathological processes in asthma. J Cell Physiol. 2019;234:21547–21559.
  • Taka S, Tzani-Tzanopoulou P, Wanstall H, et al. MicroRNAs in asthma and respiratory infections: identifying common pathways. Allergy Asthma Immunol Res. 2020;12:4–23.
  • Deshpande DA, Walseth TF, Panettieri RA, et al. CD38/cyclic ADP-ribose-mediated Ca2+ signaling contributes to airway smooth mus- cle hyper-responsiveness. Faseb J. 2003;17:452–454.
  • Deshpande DA, White TA, Guedes AG, et al. Altered airway responsiveness in CD38-deficient mice. Am J Respir Cell Mol Biol. 2005;32:149–156.
  • Amrani Y, Panettieri RA Jr. Modulation of calcium homeostasis as a mechanism for altering smooth muscle responsiveness in asthma. Curr Opin Allergy Clin Immunol. 2002;2(1):39–45.
  • Kardas G, Daszyńska-Kardas A, Marynowski M, et al. Role of platelet-derived growth factor (PDGF) in asthma as an immunoregulatory factor mediating airway remodeling and possible pharmacological target. Front Pharmacol. 2020;11:47.
  • Fang L, Sun Q, Roth M. Immunologic and non-immunologic mechanisms leading to airway remodeling in asthma. Int J Mol Sci. 2020;21(3):E757.
  • Lam M, Lamanna E, Bourke JE. Regulation of airway smooth muscle contraction in health and disease. Adv Exp Med Biol. 2019;1124:381–422.

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