Small GTPases, Volume 13, Issue 1 (2022)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Small GTPases, Volume 13, Issue 1 (2022)

See all volumes and issues
Vol 14, 2023 Volume 13, 2022 Vol 12, 2021 Vol 11, 2020 Vol 10, 2019 Vol 9, 2018 Vol 8, 2017 Vol 7, 2016 Vol 6, 2015 Vol 5, 2014 Vol 4, 2013 Vol 3, 2012 Vol 2, 2011 Vol 1, 2010
Download citations Download PDFs Download issue

Brief Report

Brief Report
Down-regulation of miR-140-3p is a cause of the interlukin-13-induced up-regulation of RhoA protein in bronchial smooth muscle cells
Yoshihiko Chiba, Yusuke Ando, Yasuna Kato, Motohiko Hanazaki & Hiroyasu Sakai
Pages: 1-6
Published online: 11 Jan 2021
AbstractforDown-regulation of miR-140-3p is a cause of the interlukin-13-induced up-regulation of RhoA protein in bronchial smooth muscle cells | Full Text | References | PDF (445.7 KB) | EPUB
  • 304 Views
  • 2 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Article Commentary
Investigating increased hematopoietic stem cell fitness in a novel mouse model
Laila Karra & Jeroen P. Roose
Pages: 7-13
Published online: 10 Feb 2021
AbstractforInvestigating increased hematopoietic stem cell fitness in a novel mouse model | Full Text | References | PDF (671.1 KB) | EPUB
  • 472 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Review

Review
Rac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses
Joseph G. Duman, Francisco A. Blanco, Christopher A. Cronkite, Qin Ru, Kelly C. Erikson, Shalaka Mulherkar, Ali Bin Saifullah, Karen Firozi & Kimberley F. Tolias
Pages: 14-47
Published online: 06 May 2021
AbstractforRac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses | Full Text | References | PDF (3.7 MB) | EPUB
  • 7178 Views
  • 5 CrossRef citations
  • 0Altmetric
Open Access

Research Paper

Article
Biallelic ELMO3 mutations and loss of function for DOCK-mediated RAC1 activation result in intellectual disability
Viviane Tran, Marie-Anne Goyette, Mónica Martínez-García, Ana Jiménez de Domingo, Daniel Martín Fernández-Mayoralas, Ana Laura Fernández-Perrone, Pilar Tirado, Beatriz Calleja-Pérez, Sara Álvarez, Jean-François Côté & Alberto Fernández-Jaén
Pages: 48-55
Published online: 04 Mar 2021
AbstractforBiallelic ELMO3 mutations and loss of function for DOCK-mediated RAC1 activation result in intellectual disability | Full Text | References | PDF (1.2 MB) | EPUB
  • 3198 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Review

Review
The progress in C9orf72 research: ALS/FTD pathogenesis, functions and structure
Lan Jiang, Tizhong Zhang, Kefeng Lu & Shiqian Qi
Pages: 56-76
Published online: 05 Mar 2021
AbstractforThe progress in C9orf72 research: ALS/FTD pathogenesis, functions and structure | Full Text | References | PDF (3.1 MB) | EPUB
  • 1906 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Brief Report

Brief Report
The N-terminal Leu-Pro-Gln sequence of Rab34 is required for ciliogenesis in hTERT-RPE1 cells
Mai E Oguchi, Yuta Homma & Mitsunori Fukuda
Pages: 77-83
Published online: 16 Apr 2021
AbstractforThe N-terminal Leu-Pro-Gln sequence of Rab34 is required for ciliogenesis in hTERT-RPE1 cells | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 536 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access

Review

Review
GPCRs that Rhoar the Guanine nucleotide exchange factors
Aishwarya Omble & Kiran Kulkarni
Pages: 84-99
Published online: 14 Apr 2021
AbstractforGPCRs that Rhoar the Guanine nucleotide exchange factors | Full Text | References | PDF (2.5 MB) | EPUB
  • 832 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Phylogenetic reconstruction and evolution of the Rab GTPase gene family in Amoebozoa
Alfredo L. Porfírio-Sousa, Alexander K. Tice, Matthew W. Brown & Daniel J. G. Lahr
Pages: 100-113
Published online: 29 Mar 2021
AbstractforPhylogenetic reconstruction and evolution of the Rab GTPase gene family in Amoebozoa | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 720 Views
  • 2 CrossRef citations
  • 0Altmetric
Free Access
Article
Targeting the KRAS α4-α5 allosteric interface inhibits pancreatic cancer tumorigenesis
Imran Khan, Catherine Marelia-Bennet, Julia Lefler, Mariyam Zuberi, Eric Denbaum, Akiko Koide, Dean M. Connor, Ann-Marie Broome, Thierry Pécot, Cynthia Timmers, Michael C. Ostrowski, Shohei Koide & John P. O’Bryan
Pages: 114-127
Published online: 05 May 2021
AbstractforTargeting the KRAS α4-α5 allosteric interface inhibits pancreatic cancer tumorigenesis | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1322 Views
  • 8 CrossRef citations
  • 0Altmetric
Free Access

Commentary

Article
A signalling cascade for Ral
You Wu & David J. Reiner
Pages: 128-135
Published online: 06 May 2021
AbstractforA signalling cascade for Ral | Full Text | References | PDF (836.8 KB) | EPUB
  • 1012 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access

Brief Report

Article
The anti-Rac1-GTP antibody and the detection of active Rac1: a tool with a fundamental flaw
Martin J. Baker & Marcelo G. Kazanietz
Pages: 136-140
Published online: 29 Apr 2021
AbstractforThe anti-Rac1-GTP antibody and the detection of active Rac1: a tool with a fundamental flaw | Full Text | References | PDF (1.4 MB) | EPUB
  • 1116 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Review

Review
Rho GTPases in kidney physiology and diseases
Clara Steichen, Claude Hervé, Thierry Hauet & Nicolas Bourmeyster
Pages: 141-161
Published online: 17 Jun 2021
AbstractforRho GTPases in kidney physiology and diseases | Full Text | References | PDF (1.1 MB) | EPUB
  • 1320 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Rab3a, a small GTP-binding protein, is required for the stabilization of the murine leukaemia virus Gag protein
Mai Izumida, Katsura Kakoki, Hideki Hayashi, Toshifumi Matsuyama & Yoshinao Kubo
Pages: 162-182
Published online: 27 Jun 2021
AbstractforRab3a, a small GTP-binding protein, is required for the stabilization of the murine leukaemia virus Gag protein | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 372 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Review

Review
Photodynamic treatment modulates various GTPase and cellular signalling pathways in Tauopathy
Tushar Dubey & Subashchandrabose Chinnathambi
Pages: 183-195
Published online: 17 Jun 2021
AbstractforPhotodynamic treatment modulates various GTPase and cellular signalling pathways in Tauopathy | Full Text | References | PDF (1.4 MB) | EPUB
  • 396 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Mini-Review

Review
Regulation of Leukaemia Associated Rho GEF (LARG/ARHGEF12)
Neda Z. Ghanem, Michelle L. Matter & Joe W. Ramos
Pages: 196-204
Published online: 25 Jul 2021
AbstractforRegulation of Leukaemia Associated Rho GEF (LARG/ARHGEF12) | Full Text | References | PDF (2.8 MB) | EPUB
  • 800 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Brief Report

Brief Report
Targeting Rac1 for the prevention of atherosclerosis among U.S. Veterans with inflammatory bowel disease
S. Scott Sutton, Joseph Magagnoli, Tammy H. Cummings & James W. Hardin
Pages: 205-210
Published online: 28 Jul 2021
AbstractforTargeting Rac1 for the prevention of atherosclerosis among U.S. Veterans with inflammatory bowel disease | Full Text | References | PDF (277.4 KB) | EPUB | Supplemental
  • 450 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Review

Review
Seeing is believing: tools to study the role of Rho GTPases during cytokinesis
Su Pin Koh, Nhat Phi Pham & Alisa Piekny
Pages: 211-224
Published online: 18 Aug 2021
AbstractforSeeing is believing: tools to study the role of Rho GTPases during cytokinesis | Full Text | References | PDF (1.5 MB) | EPUB
  • 1296 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
KRAS G12C fragment screening renders new binding pockets
Magali Mathieu, Valérie Steier, Florence Fassy, Cécile Delorme, David Papin, Bruno Genet, Francis Duffieux, Thomas Bertrand, Laure Delarbre, Hélène Le-Borgne, Annick Parent, Patrick Didier, Jean-Pierre Marquette, Maryse Lowinski, Jacques Houtmann, Annabelle Lamberton, Laurent Debussche & Rak Alexey
Pages: 225-238
Published online: 24 Sep 2021
AbstractforKRAS G12C fragment screening renders new binding pockets | Full Text | References | PDF (2.2 MB) | EPUB
  • 2260 Views
  • 3 CrossRef citations
  • 0Altmetric
Free Access
Article
Interactome and evolutionary conservation of Dictyostelid small GTPases and their direct regulators
Gillian Forbes, Christina Schilde, Hajara Lawal, Koryu Kin, Qingyou Du, Zhi-hui Chen, Francisco Rivero & Pauline Schaap
Pages: 239-254
Published online: 05 Oct 2021
AbstractforInteractome and evolutionary conservation of Dictyostelid small GTPases and their direct regulators | Full Text | References | PDF (4.7 MB) | EPUB | Supplemental
  • 3106 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access
Article
Unexplored Cdc42 functions at the budding yeast nucleus suggested by subcellular localization
Michelle S. Lu & David G. Drubin
Pages: 255-266
Published online: 30 Oct 2021
AbstractforUnexplored Cdc42 functions at the budding yeast nucleus suggested by subcellular localization | Full Text | References | PDF (4.3 MB) | EPUB | Supplemental
  • 752 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access
Article
Deletion of murine Rhoh leads to de-repression of Bcl-6 via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma
Hiroto Horiguchi, Haiming Xu, Beatrice Duvert, Felicia Ciuculescu, Qiuming Yao, Amit Sinha, Meaghan McGuinness, Chad Harris, Christian Brendel, Anja Troeger, Roberto Chiarle & David A. Williams
Pages: 267-281
Published online: 05 Jan 2022
AbstractforDeletion of murine Rhoh leads to de-repression of Bcl-6 via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 716 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Brief Report

Brief Report
Allosteric regulation of GRB2 modulates RAS activation
Kazemein Jasemi NS & Ahmadian M.R.
Pages: 282-286
Published online: 15 Jun 2022
AbstractforAllosteric regulation of GRB2 modulates RAS activation | Full Text | References | PDF (1,002 KB) | EPUB
  • 908 Views
  • 1 CrossRef citations
  • 0Altmetric
Free Access
Brief Report
An ultra-sensitive method to detect mutations in human RAS templates
Siqi Li & Christopher M. Counter
Pages: 287-295
Published online: 29 Jun 2022
AbstractforAn ultra-sensitive method to detect mutations in human RAS templates | Full Text | References | PDF (604 KB) | EPUB
  • 1862 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access
Brief Report
Quantitation of RhoA activation: differential binding to downstream effectors
Yu-Wen Zhang, Holly M. Torsilieri & James E. Casanova
Pages: 296-306
Published online: 12 Aug 2022
AbstractforQuantitation of RhoA activation: differential binding to downstream effectors | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
  • 952 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Research Paper

Article
Small-molecule inhibitors of P-Rex guanine-nucleotide exchange factors
CD Lawson, K Hornigold, D Pan, I Niewczas, S Andrews, J Clark & HCE Welch
Pages: 307-326
Published online: 07 Nov 2022
AbstractforSmall-molecule inhibitors of P-Rex guanine-nucleotide exchange factors | Full Text | References | PDF (14 MB) | EPUB | Supplemental
  • 3236 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access

Brief Report

Brief Report
A New Crosslinking Assay to Study Guanine Nucleotide Binding in the Gtr Heterodimer of S. cerevisiae
Dylan D. Doxsey, Kristen Veinotte & Kuang Shen
Pages: 327-334
Published online: 03 Nov 2022
AbstractforA New Crosslinking Assay to Study Guanine Nucleotide Binding in the Gtr Heterodimer of S. cerevisiae | Full Text | References | PDF (1.4 MB) | EPUB
  • 2178 Views
  • 0 CrossRef citations
  • 0Altmetric
Open Access

Explore articles

Explore the most recently published articles

To stay in shape and keep moving: MLL emerges as a new transcriptional regulator of Rho GTPases
Akash Chinchole et al.
Article | Published online: 6 Sep 2023
Open Access
Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions
Anna E. Daniel et al.
Brief Report | Published online: 1 Aug 2023
Open Access
Rab6-mediated retrograde trafficking from the Golgi: the trouble with tubules
Lucy G. Dornan et al.
Review Article | Published online: 24 Jul 2023
Open Access
ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancer
Samantha Hodder et al.
Review Article | Published online: 16 May 2023
Open Access
View all latest articles