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Hospital Practice Volume 51, 2023 - Issue 3
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Hematology

Impact of perioperative direct oral anticoagulant assays: a multicenter cohort study

Brandon Strettona Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;b Discipline of Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, South Australia, Australia;c Central Adelaide Local Health Network, Adelaide, South Australia, AustraliaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7939-3489View further author information
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Joshua Kovoora Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;b Discipline of Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, South Australia, Australia;c Central Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0002-3880-3840View further author information
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Stephen Bacchia Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;c Central Adelaide Local Health Network, Adelaide, South Australia, Australia;d Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0001-5130-8628View further author information
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Andrew Boothc Central Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0009-0005-0023-6552View further author information
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Sam Glucke Northern Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0001-7883-517XView further author information
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Andrew Vanlinta Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0002-5862-8445View further author information
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Mohamed Afzala Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0002-6316-5289View further author information
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Christopher Ovendena Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;c Central Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0001-8075-7852View further author information
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Aashray Guptaa Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;f Cardiothoracic Surgery, Gold Coast University Hospital, Southport, Queensland, AustraliaORCID Iconhttps://orcid.org/0000-0002-8038-0378View further author information
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Rajiv Mahajanc Central Adelaide Local Health Network, Adelaide, South Australia, Australia;e Northern Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0003-3375-5568View further author information
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Suzanne Edwardsg Adelaide Health Technology Assessment, The University of Adelaide, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0003-2074-1685View further author information
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Yvonne Brennanc Central Adelaide Local Health Network, Adelaide, South Australia, Australia;e Northern Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0002-8670-4070View further author information
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Jir Ping Boeyd Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0002-0111-8575View further author information
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Benjamin Reddia Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0003-4110-5055View further author information
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Guy Madderna Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;b Discipline of Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, South Australia, Australia;h Research, Audit and Academic Surgery, Royal Australasian College of Surgeons, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0003-2064-181XView further author information
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Mark Boyda Adelaide Medical School, Faculty of Health and Medical Science, University of Adelaide, Adelaide, South Australia, Australia;e Northern Adelaide Local Health Network, Adelaide, South Australia, AustraliaORCID Iconhttps://orcid.org/0000-0002-6848-3307View further author information
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Pages 155-162 | Received 20 Feb 2023, Accepted 18 Apr 2023, Published online: 24 Apr 2023

References

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  • Clinical Excellence Commission. New south wales clinical excellence commission. In: Guidelines on perioperative management of anticoagulant and antiplatelet agents. Sydney; 2018. p. 13–14. https://www.cec.health.nsw.gov.au/__data/assets/pdf_file/0006/458988/Guidelines-on-perioperative-management-of-anticoagulant-and-antiplatelet-agents.pdf
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  • Douketis J, Spyropoulos A, Anderson J, et al. The perioperative anticoagulant use for surgery evaluation (PAUSE) study for patients on a direct oral anticoagulant who need an elective surgery or procedure: design and rationale. Thromb Haemost. 2017;117(12):2415–2424. DOI:10.1160/TH17-08-0553
  • Douketis JD, Spyropoulos AC, Kaatz S, et al. Perioperative bridging anticoagulation in patients with atrial fibrillation. N Engl J Med. 2015;373(9):823–833. DOI:10.1056/NEJMoa1501035
  • Dubois V, Dincq A-S, Douxfils J, et al. Perioperative management of patients on direct oral anticoagulants. Thromb J. 2017; 15(1).
  • Fox V, Kleikamp A, Dittrich M, et al. Direct oral anticoagulants and cardiac surgery: a descriptive study of preoperative management and postoperative outcomes. J Thorac Cardiovasc Surg. 2021 May;161(5):1864–1874.e2.
  • Godier A, Martin AC, Leblanc I, et al. Peri-procedural management of dabigatran and rivaroxaban: duration of anticoagulant discontinuation and drug concentrations. Thromb Res. 2015 Oct;136(4):763–768.
  • Kaserer A, Kiavialaitis GE, Braun J, et al. Impact of rivaroxaban plasma concentration on perioperative red blood cell loss. Transfusion. 2020;60(1):197–205. DOI:10.1111/trf.15560
  • Tripodi A, Marongiu F, Moia M, et al. The vexed question of whether or not to measure levels of direct oral anticoagulants before surgery or invasive procedures. Int Emerg Med. 2018;13(7):1029–1036. DOI:10.1007/s11739-018-1854-6
  • Verslype C. Evaluation of abnormal liver-enzyme results in asymptomatic patients. Acta Clin Belg. 2004;59(5):285–289.

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