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Letter

Genetic variants in human BCL2L11 (BIM) are associated with ulcerative forms of Buruli ulcer

ORCID Icon, , , , , , , , , & show all
Pages 223-225 | Received 19 Oct 2020, Accepted 17 Jan 2021, Published online: 11 Feb 2021

References

  • Omansen TF, Erbowor-Becksen A, Yotsu R, et al. Global Epidemiology of Buruli ulcer, 2010-2017, and analysis of 2014 WHO Programmatic Targets. Emerg Infect Dis. 2019;25:2183–2190.
  • Bieri R, Scherr N, Ruf M-T, et al. The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR. ACS Chem Biol. 2017;12:1297–1307.
  • Capela C, Sopoh GE, Houezo JG, et al. Clinical epidemiology of buruli ulcer from Benin (2005-2013): effect of time-delay to diagnosis on clinical forms and severe phenotypes. PLoS Negl Trop Dis. 2015;9:e0004005.
  • International HapMap 3 Consortium, Altshuler DM, Gibbs RA et al. Integrating common and rare genetic variation in diverse human populations. Nature 2010; 467: 52–58.
  • Barrett JC, Fry B, Maller J, et al. Haploview: analysis and visualization of LD and haplotype maps. Bioinforma Oxf Engl. 2005;21:263–265.
  • Johnson JL, Abecasis GR. GAS power Calculator: web-based power calculator for genetic association studies. bioRxiv. 2017. doi:https://doi.org/10.1101/164343.
  • Capela C, Dossou AD, Silva-Gomes R, et al. Genetic variation in autophagy-related genes influences the risk and phenotype of buruli ulcer. PLoS Negl Trop Dis. 2016;10:e0004671.
  • Purcell S, Neale B, Todd-Brown K, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81:559–575.
  • Yates AD, Achuthan P, Akanni W, et al. Ensembl 2020. Nucleic Acids Res. 2020;48:D682–D688.
  • Farré D, Roset R, Huerta M, et al. Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN. Nucleic Acids Res. 2003;31:3651–3653.
  • Cooper DN. Functional intronic polymorphisms: Buried treasure awaiting discovery within our genes. Hum Genomics. 2010;4:284–288.
  • Yang R, Yang E, Shen L, et al. IL-12+IL-18 Cosignaling in human macrophages and lung epithelial cells activates cathelicidin and autophagy, inhibiting intracellular mycobacterial growth. J Immunol Baltim Md 1950. 2018;200:2405–2417.
  • Russell L, Garrett-Sinha LA. Transcription factor Ets-1 in cytokine and chemokine gene regulation. Cytokine. 2010;51:217–226.
  • Kotzin JJ, Spencer SP, McCright SJ, et al. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Nature. 2016;537:239–243.
  • Manry J, Vincent QB, Johnson C, et al. Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway. Commun Biol. 2020;3:177.