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Emerging Microbes & Infections Volume 10, 2021 - Issue 1
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Coronaviruses

Antibody response elicited by a third boost dose of inactivated SARS-CoV-2 vaccine can neutralize SARS-CoV-2 variants of concern

Lei YueThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-5201-4373View further author information
ORCID Icon,
Jian ZhouThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Yanan ZhouThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Xiaolei YangThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Tianhong XieThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Mengli YangThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Hongling ZhaoThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Yuan ZhaoThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Ting YangThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Hua LiThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Hong XiangThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Jie WangThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Shuaiyao LuThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Hongqi LiuThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Hong ZhaoThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Xingchen WeiThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
,
Yuhao ZhangThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaView further author information
&
Zhongping XieThe Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2687-4438View further author information
ORCID Icon show all
Pages 2125-2127 | Received 29 Aug 2021, Accepted 16 Oct 2021, Published online: 16 Nov 2021

References

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  • Liao Y, Zhang Y, Zhao H, et al. Intensified antibody response elicited by boost suggests immune memory in individuals administered two doses of SARS-CoV-2 inactivated vaccine. Emerg Microbes Infect. 2021 Dec;10(1):1112–1115.
  • Khoury DS, Cromer D, Reynaldi A, et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat Med. 2021 Jul;27(7):1205–1211.
  • Li XN, Huang Y, Wang W, et al. Efficacy of inactivated SARS-CoV-2 vaccines against the delta variant infection in Guangzhou: A test-negative case–control real-world study. Emerg Microbes Infect. 2021 Dec;10(1):1751–1759.
  • Yue L, Xie T, Yang T, et al. A third booster dose may be necessary to mitigate neutralizing antibody fading after inoculation with two doses of an inactivated SARS-CoV-2 vaccine. J Med Virol. 2021 Sep 13.

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