Prevalence, evolution, replication and transmission of H3N8 avian influenza viruses isolated from migratory birds in eastern China from 2017 to 2021

References

• Cui P, Zeng X, Li X, et al. Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China. Sci China Life Sci. 2022 Apr;65(4):795–808. doi:10.1007/s11427-021-2025-y. PubMed PMID: 34757542.
   PubMed Web of Science ®Google Scholar
• Cui P, Shi J, Wang C, et al. Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China. Emerg Microbes Infect. 2022 Dec;11(1):1693–1704. doi:10.1080/22221751.2022.2088407. PubMed PMID: 35699072; PubMed Central PMCID: PMC9246030.
   PubMed Web of Science ®Google Scholar
• World Health Organization (WHO). Available from: https://www.who.int/data/gho/data/themes/global-influenza-virological-surveillance.
   Google Scholar
• Shi J, Zeng X. Alarming situation of emerging H5 and H7 avian influenza and effective control strategies. Emerg Microbes Infect. 2022 Nov;12(1):2155072. doi:10.1080/22221751.2022.2155072. PubMed PMID: 36458831 PubMed Central PMCID: PMC9754034.
   Web of Science ®Google Scholar
• Li C, Chen H. H7n9 influenza virus in China. Cold Spring Harbor Perspect Med. 2021 Aug 2;11(8):a038349. doi:10.1101/cshperspect.a038349. PubMed PMID: 32205415; PubMed Central PMCID: PMC8327827.
   PubMed Web of Science ®Google Scholar
• Shi JZ, Deng GH, Kong HH, et al. H7n9 virulent mutants detected in chickens in China pose an increased threat to humans. Cell Res. 2017 Dec;27(12):1409–1421. doi:10.1038/cr.2017.129. PubMed PMID: WOS:000416728800005; English.
   PubMed Web of Science ®Google Scholar
• Gao R, Cao B, Hu Y, et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med. 2013 May 16;368(20):1888–1897. doi:10.1056/NEJMoa1304459. PubMed PMID: 23577628.
   PubMed Web of Science ®Google Scholar
• Li X, Shi J, Guo J, et al. Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses. PLoS Pathog. 2014 Nov;10(11):e1004508. doi:10.1371/journal.ppat.1004508. PubMed PMID: 25411973; PubMed Central PMCID: PMC4239090.
   PubMed Web of Science ®Google Scholar
• F.L.C (Flu in China). Available from: http://wwwfluorgcn/scn/defaulthtml.
   Google Scholar
• Cheng D, Dong Y, Wen S, et al. A child with acute respiratory distress syndrome caused by avian influenza H3N8 virus. J Infect. 2022 Aug;85(2):174–211. doi:10.1016/j.jinf.2022.05.007. PubMed PMID: 35577072.
   Web of Science ®Google Scholar
• Tong XC, Weng SS, Xue F, et al. First human infection by a novel avian influenza A(H7N4) virus. J Infect. 2018 Sep;77(3):249–257. doi:10.1016/j.jinf.2018.06.002. PubMed PMID: 29898409.
   PubMed Web of Science ®Google Scholar
• Zhang T, Bi Y, Tian H, et al. Human infection with influenza virus A(H10N8) from live poultry markets, China, 2014. Emerg Infect Dis. 2014 Dec;20(12):2076–2079. doi:10.3201/eid2012.140911. PubMed PMID: 25425075; PubMed Central PMCID: PMC4257803.
   PubMed Web of Science ®Google Scholar
• Tan X, Yan X, Liu Y, et al. A case of human infection by H3N8 influenza virus. Emerg Microbes Infect. 2022 Dec;11(1):2214–2217. doi:10.1080/22221751.2022.2117097. PubMed PMID: 36000153; PubMed Central PMCID: PMC9542523.
   PubMed Web of Science ®Google Scholar
• Prosser DJ, Chen J, Ahlstrom CA, et al. Maintenance and dissemination of avian-origin influenza A virus within the northern Atlantic Flyway of North America. PLoS Pathog. 2022 Jun;18(6):e1010605. doi:10.1371/journal.ppat.1010605. PubMed PMID: 35666770; PubMed Central PMCID: PMC9203021.
   PubMed Web of Science ®Google Scholar
• Hill NJ, Bishop MA, Trovao NS, et al. Ecological divergence of wild birds drives avian influenza spillover and global spread. PLoS Pathog. 2022;18(5):e1010062. doi:10.1371/journal.ppat.1010062. PubMed PMID: 35588106; PubMed Central PMCID: PMC9119557.
   PubMed Web of Science ®Google Scholar
• Lv X, Li X, Sun H, et al. Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b viruses in satellite-tracked wild ducks, Ningxia, China, 2020. Emerg Infect Dis. 2022 May;28(5):1039–1042. doi:10.3201/eid2805.211580. PubMed PMID: 35447054; PubMed Central PMCID: PMC9045446.
   PubMed Web of Science ®Google Scholar
• Gu W, Shi J, Cui P, et al. Novel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China. Emerg Microbes Infect. 2022 Dec;11(1):1174–1185. doi:10.1080/22221751.2022.2063076. PubMed PMID: 35380505; PubMed Central PMCID: PMC9126593.
   PubMed Web of Science ®Google Scholar
• Bevins SN, Shriner SA, Cumbee JC Jr, et al. Intercontinental movement of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4 virus to the United States, 2021. Emerg Infect Dis. 2022 May;28(5):1006–1011. doi:10.3201/eid2805.220318. PubMed PMID: 35302933; PubMed Central PMCID: PMC9045435.
   PubMed Web of Science ®Google Scholar
• Engelsma M, Heutink R, Harders F, et al. Multiple introductions of reassorted highly pathogenic avian influenza H5Nx viruses clade 2.3.4.4b causing outbreaks in wild birds and poultry in The Netherlands, 2020-2021. Microbiol Spectr. 2022 Apr 27;10(2):e0249921. doi:10.1128/spectrum.02499-21. PubMed PMID: 35286149; PubMed Central PMCID: PMC9045216.
   PubMed Web of Science ®Google Scholar
• Youk S, Leyson C, Killian ML, et al. Evolution of the North American lineage H7 avian influenza viruses in association with H7 virus’s introduction to poultry. J Virol. 2022 Jul 27;96(14):e0027822. doi:10.1128/jvi.00278-22. PubMed PMID: 35862690; PubMed Central PMCID: PMC9327676.
   PubMed Web of Science ®Google Scholar
• Wang Y, Wang M, Zhang H, et al. Emergence, evolution, and biological characteristics of H10N4 and H10N8 avian influenza viruses in migratory wild birds detected in Eastern China in 2020. Microbiol Spectr. 2022 Apr 27;10(2):e0080722. doi:10.1128/spectrum.00807-22. PubMed PMID: 35389243; PubMed Central PMCID: PMC9045299.
   PubMed Web of Science ®Google Scholar
• Martinez-Sobrido L, Blanco-Lobo P, Rodriguez L, et al. Characterizing emerging canine H3 influenza viruses. PLoS Pathog. 2020 Apr;16(4):e1008409. doi:10.1371/journal.ppat.1008409. PubMed PMID: 32287326; PubMed Central PMCID: PMC7182277.
   PubMed Web of Science ®Google Scholar
• Mino S, Mojsiejczuk L, Guo W, et al. Equine influenza virus in Asia: phylogeographic pattern and molecular features reveal circulation of an autochthonous lineage. J Virol. 2019 Jul 1;93(13). doi:10.1128/JVI.00116-19. PubMed PMID: 31019053; PubMed Central PMCID: PMC6580976.
   PubMed Web of Science ®Google Scholar
• Tu J, Zhou H, Jiang T, et al. Isolation and molecular characterization of equine H3N8 influenza viruses from pigs in China. Arch Virol. 2009;154(5):887–890. doi:10.1007/s00705-009-0381-1. PubMed PMID: 19396578.
   PubMed Web of Science ®Google Scholar
• Qi T, Guo W, Huang W, et al. Isolation and genetic characterization of H3N8 equine influenza virus from donkeys in China. Vet Microbiol. 2010 Aug 26;144(3-4):455–460. doi:10.1016/j.vetmic.2010.01.006. PubMed PMID: 20153940.
   PubMed Web of Science ®Google Scholar
• Karlsson EA, Ip HS, Hall JS, et al. Respiratory transmission of an avian H3N8 influenza virus isolated from a harbour seal. Nat Commun. 2014 Sep 3;5:4791. doi:10.1038/ncomms5791. PubMed PMID: 25183346; PubMed Central PMCID: PMC4801029.
   PubMed Web of Science ®Google Scholar
• Tan X, Yan X, Liu Y, et al. A case of human infection by H3N8 influenza virus. Emerg Microbes Infect. 2022 Aug 23: 1–25. doi:10.1080/22221751.2022.2117097. PubMed PMID: 36000153.
   PubMedGoogle Scholar
• Zhang X, Li Y, Jin S, et al. PB1 s524g mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals. Emerg Microbes Infect. 2021 Dec;10(1):1038–1051. doi:10.1080/22221751.2021.1912644. PubMed PMID: 33840358; PubMed Central PMCID: PMC8183522.
   PubMed Web of Science ®Google Scholar
• Yang R, Sun H, Gao F, et al. Human infection of avian influenza A H3N8 virus and the viral origins: a descriptive study. Lancet Microbe. 2022 Nov;3(11):e824–e834. doi:10.1016/S2666-5247(22)00192-6. PubMed PMID: 36115379.
   PubMedGoogle Scholar
• Wan Z, Jiang W, Gong J, et al. Emergence of chicken infection with novel reassortant H3N8 avian influenza viruses genetically close to human H3N8 isolate, China. Emerg Microbes Infect. 2022 Dec;11(1):2553–2555. doi:10.1080/22221751.2022.2128437. PubMed PMID: 36150006.
   PubMed Web of Science ®Google Scholar
• Bao P, Liu Y, Zhang X, et al. Human infection with a reassortment avian influenza A H3N8 virus: an epidemiological investigation study. Nat Commun. 2022 Nov 10;13(1):6817. doi:10.1038/s41467-022-34601-1. PubMed PMID: 36357398.
   PubMed Web of Science ®Google Scholar
• Zhao C, Guo J, Zeng X, et al. Novel H7N7 avian influenza viruses detected in migratory wild birds in eastern China between 2018 and 2020. Microbes Infect. 2022 May 14;105013; doi:10.1016/j.micinf.2022.105013. PubMed PMID: 35580801.
   PubMed Web of Science ®Google Scholar
• Li X, Cui P, Zeng X, et al. Characterization of avian influenza H5N3 reassortants isolated from migratory waterfowl and domestic ducks in China from 2015 to 2018. Transbound Emerg Dis. 2019 Nov;66(6):2605–2610. doi:10.1111/tbed.13324. PubMed PMID: 31402584.
   PubMed Web of Science ®Google Scholar
• Guo J, Wang Y, Zhao C, et al. Molecular characterization, receptor binding property, and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls, and wild birds in eastern China. Emerg Microbes Infect. 2021 Dec;10(1):2098–2112. doi:10.1080/22221751.2021.1999778. PubMed PMID: 34709136; PubMed Central PMCID: PMC8592596.
   PubMed Web of Science ®Google Scholar
• Gao Y, Zhang Y, Shinya K, et al. Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host. PLoS Pathog. 2009 Dec;5(12):e1000709. doi:10.1371/journal.ppat.1000709. PubMed PMID: 20041223; PubMed Central PMCID: PMC2791199.
   PubMed Web of Science ®Google Scholar
• Zhu W, Zou X, Zhou J, et al. Residues 41V and/or 210D in the NP protein enhance polymerase activities and potential replication of novel influenza (H7N9) viruses at low temperature. Virol J. 2015 May 5;12:71. doi:10.1186/s12985-015-0304-6. PubMed PMID: 25940512; PubMed Central PMCID: PMC4434832.
   PubMed Web of Science ®Google Scholar
• Guo J, Chen J, Li Y, et al. SUMOylation of matrix protein M1 and filamentous morphology collectively contribute to the replication and virulence of highly pathogenic H5N1 avian influenza viruses in mammals. J Virol. 2022 Feb 23;96(4):e0163021. doi:10.1128/JVI.01630-21. PubMed PMID: 34908445; PubMed Central PMCID: PMC8865470.
   PubMed Web of Science ®Google Scholar
• Hulse-Post DJ, Franks J, Boyd K, et al. Molecular changes in the polymerase genes (PA and PB1) associated with high pathogenicity of H5N1 influenza virus in mallard ducks. J Virol. 2007 Aug;81(16):8515–8524. doi:10.1128/JVI.00435-07. PubMed PMID: 17553873; PubMed Central PMCID: PMC1951362.
   PubMed Web of Science ®Google Scholar
• Li Z, Jiang Y, Jiao P, et al. The NS1 gene contributes to the virulence of H5N1 avian influenza viruses. J Virol. 2006 Nov;80(22):11115–11123. doi:10.1128/JVI.00993-06. PubMed PMID: 16971424; PubMed Central PMCID: PMC1642184.
   PubMed Web of Science ®Google Scholar
• Imai M, Watanabe T, Hatta M, et al. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature. 2012 May 2;486(7403):420–428. doi:10.1038/nature10831. PubMed PMID: 22722205; PubMed Central PMCID: PMC3388103.
   PubMed Web of Science ®Google Scholar
• Klenk E, Faillard H, Lempfrid H. [Enzymatic effect of the influenza virus]. Hoppe Seylers Z Physiol Chem. 1955 Sep 2;301(4-6):235–246. PubMed PMID: 13306147.
   PubMedGoogle Scholar
• Air GM, Laver WG. The neuraminidase of influenza virus. Proteins. 1989;6(4):341–356. doi:10.1002/prot.340060402. PubMed PMID: 2482974.
   PubMed Web of Science ®Google Scholar
• Dong X, Soong L. Emerging and Re-emerging zoonoses are major and global challenges for public health. Zoonoses. 2021;1(1). doi:10.15212/ZOONOSES-2021-0001. PubMed PMID: ScienceOpenVid:99054329-587f-4f22-8b12-a8d9bb906b93.
   Google Scholar
• Chen Y, Bai T, Shu Y. Poultry to human passport: cross-species transmission of zoonotic H7N9 avian influenza virus to humans. Zoonoses. 2022;2(1). doi:10.15212/zoonoses-2021-0026. PubMed PMID: ScienceOpenVid:7cea6b31-c87a-41cd-9466-48789616e80a.
   Google Scholar
• Liu K, Ding P, Pei Y, et al. Emergence of a novel reassortant avian influenza virus (H10N3) in eastern China with high pathogenicity and respiratory droplet transmissibility to mammals. Sci China Life Sci. 2022 May;65(5):1024–1035. doi:10.1007/s11427-020-1981-5. PubMed PMID: 34542812.
   PubMed Web of Science ®Google Scholar
• Li X, Liu B, Ma S, et al. High frequency of reassortment after co-infection of chickens with the H4N6 and H9N2 influenza A viruses and the biological characteristics of the reassortants. Vet Microbiol. 2018 Aug;222:11–17. doi:10.1016/j.vetmic.2018.06.011. PubMed PMID: 30080665.
   PubMed Web of Science ®Google Scholar
• Li Y, Li P, Xi J, et al. Wild bird-origin H3N8 avian influenza virus exhibit well adaptation in mammalian host. J Infect. 2022 Apr;84(4):579–613. doi:10.1016/j.jinf.2021.12.014. PubMed PMID: 34953909.
   Web of Science ®Google Scholar
• Tian J, Li M, Li Y, et al. H3n8 subtype avian influenza virus originated from wild birds exhibited dual receptor-binding profiles. J Infect. 2023 Feb;86(2):e36–e39. doi:10.1016/j.jinf.2022.10.023. PubMed PMID: 36273641.
   PubMed Web of Science ®Google Scholar
• Verhagen JH, Eriksson P, Leijten L, et al. Host range of influenza A virus H1 to H16 in Eurasian ducks based on tissue and receptor binding studies. J Virol. 2021 Feb 24;95(6). doi:10.1128/JVI.01873-20. PubMed PMID: 33361418; PubMed Central PMCID: PMC8094940.
   PubMed Web of Science ®Google Scholar
• Verhagen JH, Hofle U, van Amerongen G, et al. Long-term effect of serial infections with H13 and H16 low-pathogenic avian influenza viruses in black-headed gulls. J Virol. 2015 Nov;89(22):11507–11522. doi:10.1128/JVI.01765-15. PubMed PMID: 26339062; PubMed Central PMCID: PMC4645650.
   PubMed Web of Science ®Google Scholar
• Tonnessen R, Valheim M, Rimstad E, et al. Experimental inoculation of chickens with gull-derived low pathogenic avian influenza virus subtype H16N3 causes limited infection. Avian Dis. 2011 Dec;55(4):680–685. doi:10.1637/9701-030411-ResNote.1. PubMed PMID: 22312991.
   PubMed Web of Science ®Google Scholar
• Liu K, Gao R, Wang X, et al. Pathogenicity and transmissibility of clade 2.3.4.4 highly pathogenic avian influenza virus subtype H5N6 in pigeons. Vet Microbiol. 2020 Aug;247:108776. doi:10.1016/j.vetmic.2020.108776. PubMed PMID: 32768222.
   PubMed Web of Science ®Google Scholar
• Liu Y, Yang Z, Wang X, et al. Pigeons are resistant to experimental infection with H7N9 avian influenza virus. Avian Pathol. 2015 Oct;44(5):342–346. doi:10.1080/03079457.2015.1055235. PubMed PMID: 26443061.
   PubMed Web of Science ®Google Scholar
• Liu LL, Fang B, Yu X, et al. Strengthened monitoring of H5 avian influenza viruses in external environment in Hubei, 2018. Curr Med Sci. 2020 Feb;40(1):63–68. doi:10.1007/s11596-020-2147-7. PubMed PMID: 32166666.
   PubMed Web of Science ®Google Scholar
• Jonges M, Welkers MRA, Jeeninga RE, et al. Emergence of the virulence-associated PB2 E627K substitution in a fatal human case of highly pathogenic avian influenza virus A(H7N7) infection as determined by Illumina ultra-deep sequencing. J Virol. 2014 Feb;88(3):1694–1702. doi:10.1128/JVI.02044-13. PubMed PMID: 24257603.
   PubMed Web of Science ®Google Scholar
• Katoh K, Misawa K, Kuma K, et al. MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. Nucleic Acids Res. 2002 Jul 15;30(14):3059–3066. doi:10.1093/nar/gkf436. PubMed PMID: 12136088; PubMed Central PMCID: PMC135756.
   PubMed Web of Science ®Google Scholar
• Nguyen LT, Schmidt HA, von Haeseler A, et al. IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies. Mol Biol Evol. 2015 Jan;32(1):268–274. doi:10.1093/molbev/msu300. PubMed PMID: 25371430; PubMed Central PMCID: PMC4271533.
   PubMed Web of Science ®Google Scholar
• Suchard MA, Lemey P, Baele G, et al. Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10. Virus Evol. 2018 Jan;4(1):vey016. doi:10.1093/ve/vey016. PubMed PMID: 29942656; PubMed Central PMCID: PMC6007674.
   PubMed Web of Science ®Google Scholar