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Autophagy Reports Volume 2, 2023 - Issue 1
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Autophagic punctum

Lipid-sensor FFAR1 curbs autophagy and mitochondrial respiration in murine retinal angiomatous proliferation

Émilie Heckela Department of Pharmacology and Physiology, Université de Montréal, Montreal, QC, CA, H3T 1J4View further author information
&
Jean-Sébastien Joyala Department of Pharmacology and Physiology, Université de Montréal, Montreal, QC, CA, H3T 1J4;b Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, CA, H3G 1Y6;c Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, CA, H3T 1C5;d Department of Ophthalmology, Université de Montréal, Montreal, QC, CA, H3T 1J4Correspondence[email protected]
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Article: 2177932 | Published online: 21 Feb 2023

Reference

  • Heckel E, Cagnone G, Agnihotri T, Cakir B, Das A, Sung-Kim J, Kim N, Lavoie G, Situ A, Pundir S, Sun Y, Wünnemann F, Pierce KA, Dennis C, Mitchell GA, Chemtob S, Rezende FA, Andelfinger G, Clish CB, Roux PP, Sapieha P, Smith LEH, Joyal JS. Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation. JCI Insight 2022 Mar 22;7(6):e154174.

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