ALFRED HILDEBRANDT: FROM BASIC RESEARCH TO CLINICAL APPLICATION AND DRUG REGULATION

REFERENCES

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• Hildebrandt A., Remmer H., Estabrook R. W. Cytochrome P-450 of liver microsomes—One pigment or many. Biochem. Biophys. Res. Commun. 1968; 30: 607–612
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• Hildebrandt A. G. The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions. Symposium on Biological Hydroxylation, Biochemical Society, Symposium No. 34, G. S. Boyd, R. M. S. Smellie. Academic Press, London 1972; 79–102
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• Hildebrandt A. G., Speck M., Roots I. Possible role of hydrogen peroxide production and degradation in microsomes during mixed function oxidation reaction. Biochem. Biophys. Res. Commun. 1973; 54: 968–975
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• Hildebrandt A. G., Roots I., Tjoe M., Heinemeyer G. Hydrogen peroxide in hepatic microsomes. Methods Enzymol. 1978; 52: 342–350
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• Roots I., Nigam S., Gramatzki S., Heinemeyer G., Hildebrandt A. G. Hybrid information provided by the 14C-aminopyrine breath test. Studies with 14C-monomethylaminoantipyrine in the guinea pig. Naunyn-Schmiedeberg's Arch. Pharmacol. 1980; 31: 175–178
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• Roots I., Holbe R., Hoevermann W., Nigam S., Heinemeyer G., Hildebrandt A. G. Quantitative determination by HPLC of urinary 6β-hydroxycortisol, an indicator of enzyme induction by rifampicin and antiepileptic drugs. Eur. J. Clin. Pharmacol. 1979; 16: 63–71
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• Ritter J., Kahl R., Hildebrandt A. G. Effect of antioxidant (+)-cyanidanol-3 on H2O2 formation and lipid peroxidation in liver microsomes. Res. Commun. Chem. Pathol. Pharmacol. 1985; 47: 48–58
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• Appel K. E., Spiegelhalder B., Hildebrandt A. G. Denitrosation of diphenylnitrosamine in vivo. Toxicol. Lett. 1984; 23: 353–358
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• Scheper T., Appel K. E., Schunack W., Somogyi A., Hildebrandt A. G. Metabolic denitrosation of N-nitroso-N-methylaniline: Detection of amine-metabolites. Chem. Biol. Interact. 1991; 77: 81–96
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• Appel K. E., Hildebrandt A. G., Linkg W., Kunz H. W. Approaches to the health risk assessment of PCDD/PCDF. Chemosphere 1986; 15: 1825–1834
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• Hildebrandt A. G. Metalle in der Umwelt. Erzmetall 1987; 40: 516–519
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• Roots I., Hildebrandt A. G. Interaction of oleyl anilide, a component in denaturated Spanish oil 1981, with hepatic and pulmonary cytochrome P-450. Cytochrome P-450, Biochemistry, Biophysics and Environmental Implications, E. Hietanen, M. Laitinen, O. Hänninen. Elsevier Science, Amsterdam 1982; 743–748
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• Zünkler B. J., Henning B., Ott T., Hildebrandt A. G., Fleck E. Effects of tolbutamide on ATP-sensitive K+ channels from human right atrial cardiac myocytes. Pharmacol. Toxicol. 1997; 80: 69–75
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• Bauer P., Regitz-Zagrosek V., Kallisch H., Linz W., Schölkens B., Hildebrandt A. G., Fleck E. Myocardial angiotensin receptor type 1 gene expression in a rat model of cardiac volume overload. Basic Res. Cardiol. 1997; 92: 139–146
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• Appel K. E., Fürstenberger G., Hapke H. J., Hecker E., Hildebrandt A. G., Koransky W., Marks F., Neumann H. G., Ohnesorge F. K., Schulte-Hermann R. Chemical carcinogenesis: Definitions of frequently used terms. J. Cancer. Clin. Oncol. 1990; 116: 232–236
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