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- , This article was adapted from material presented as the Loren Stephens Memorial Lecture, University of Southern California Medical Center, 1976; the Griffith McKerracher Memorial Lecture at the University of Saskatchewan, 1976; the Annual Hutchings Society Lecture, State University of New York-Upstate Medical Center, Syracuse, 1976. Also presented during 1975 to 1976 at the University of Maryland School of Medicine, University of California-San Diego School of Medicine, University of California-Los Angeles School of Medicine, Massachusetts Mental Health Center, and the 21st annual meeting of Midwest Professors of Psychiatry, Philadelphia. The author is a career research awardee in the US Public Health Service