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Reduction of monoclonal antibody viscosity using interpretable machine learning
Emily K. Makowskia Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA;b Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USAView further author information
, Hsin-Ting Chenb Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USAView further author information
, Tiexin Wangb Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USAView further author information
, Lina Wub Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USAView further author information
, Jie Huanga Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA;b Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USAView further author information
, Marissa Mockd Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USAView further author information
, Patrick Underhille Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USAView further author information
, Emma Pelegri-O’Dayd Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USAView further author information
, Erick Maglalangf Drug Product Technologies, Amgen Inc, Thousand Oaks, CA, USAView further author information
, Dwight Wintersd Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USAView further author information
& Peter M. Tessiera Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA;b Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA;c Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA;g Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USACorrespondence[email protected]
https://orcid.org/0000-0002-3220-007XView further author information
show allhttps://orcid.org/0000-0002-3220-007XView further author information
Article: 2303781
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Received 26 May 2023, Accepted 05 Jan 2024, Published online: 12 Mar 2024
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