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Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody
Jing Daia Department of Antibody Engineering, Genentech, Inc, South San Francisco, CA, USAhttps://orcid.org/0000-0002-9819-0206View further author information
, Saeed Izadib Department of Pharmaceutical Development, Genentech, Inc, South San Francisco, CA, USAhttps://orcid.org/0000-0003-4206-8559View further author information
, Jonathan Zarzarb Department of Pharmaceutical Development, Genentech, Inc, South San Francisco, CA, USAView further author information
, Patrick Wuc Department of Bioanalytical Sciences, Genentech, Inc, South San Francisco, CA, USAhttps://orcid.org/0000-0002-1437-6688View further author information
, Angela Ohd Department of Structural Biology, Genentech, Inc, South San Francisco, CA, USAView further author information
& Paul J. Cartera Department of Antibody Engineering, Genentech, Inc, South San Francisco, CA, USACorrespondence[email protected]
https://orcid.org/0000-0001-7854-062XView further author information
https://orcid.org/0000-0001-7854-062XView further author information
Article: 2304282
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Received 19 Oct 2023, Accepted 08 Jan 2024, Published online: 25 Jan 2024
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