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Volume 18, Issue 3

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 3 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 3 (2009)

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Reviews

Article

Phosphodiesterase type 5 inhibitors: a viable treatment option for lower urinary tract symptoms?

Konstantinos Hatzimouratidis

Pages: 245-254

Published online: 09 May 2009

AbstractforPhosphodiesterase type 5 inhibitors: a viable treatment option for lower urinary tract symptoms? | Full Text | References | PDF (273 KB)

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Article

Opioid formulations in development designed to curtail abuse: who is the target?

Lynn R Webster MD FACPM FASAM, Brad Bath PhD & Robert A Medve MD

Pages: 255-263

Published online: 09 May 2009

AbstractforOpioid formulations in development designed to curtail abuse: who is the target? | Full Text | References | PDF (270.6 KB)

308 Views
46 CrossRef citations
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Article

Caprospinol: moving from a neuroactive steroid to a neurotropic drug

Laurent Lecanu, Laurent Tillement, Georges Rammouz, Jean Paul Tillement, Janet Greeson & Vassilios Papadopoulos

Pages: 265-276

Published online: 09 May 2009

AbstractforCaprospinol: moving from a neuroactive steroid to a neurotropic drug | Full Text | References | PDF (747.6 KB)

194 Views
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Article

Targeting multiple kinases in glioblastoma multiforme

Sith Sathornsumetee MD & David A Reardon MD

Pages: 277-292

Published online: 09 May 2009

AbstractforTargeting multiple kinases in glioblastoma multiforme | Full Text | References | PDF (274.8 KB)

245 Views
34 CrossRef citations
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Article

Second-generation epidermal growth factor tyrosine kinase inhibitors in non-small cell lung cancer

Deborah Mukherji MRCP MBBS & James Spicer

Pages: 293-301

Published online: 09 May 2009

AbstractforSecond-generation epidermal growth factor tyrosine kinase inhibitors in non-small cell lung cancer | Full Text | References | PDF (220 KB)

156 Views
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Drug Evaluations

Article

Tesamorelin, a human growth hormone releasing factor analogue

Ying Wang PhD & Brian Tomlinson MD FRCP

Pages: 303-310

Published online: 22 Jan 2009

AbstractforTesamorelin, a human growth hormone releasing factor analogue | Full Text | References | PDF (225.2 KB)

190 Views
11 CrossRef citations
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Article

Targeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1

Patricia Moretto & Sébastien J Hotte MD MSc (HRM) FRCPC

Pages: 311-325

Published online: 09 May 2009

AbstractforTargeting apoptosis: preclinical and early clinical experience with mapatumumab, an agonist monoclonal antibody targeting TRAIL-R1 | Full Text | References | PDF (936.6 KB)

163 Views
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Article

Dapagliflozin: an emerging treatment option in type 2 diabetes

Mark Kipnes

Pages: 327-334

Published online: 09 May 2009

AbstractforDapagliflozin: an emerging treatment option in type 2 diabetes | Full Text | References | PDF (388.4 KB)

434 Views
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Article

S-1: a promising new oral fluoropyrimidine derivative

Muhammad Wasif Saif, Kostas N Syrigos & Nikos A Katirtzoglou

Pages: 335-348

Published online: 09 May 2009

AbstractforS-1: a promising new oral fluoropyrimidine derivative | Full Text | References | PDF (412.8 KB)

331 Views
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Article

Review of rifaximin as treatment for SIBO and IBS

Mark Pimentel MD FRCP(C)

Pages: 349-358

Published online: 09 May 2009

AbstractforReview of rifaximin as treatment for SIBO and IBS | Full Text | References | PDF (498.7 KB)

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Article

Exenatide once weekly for the treatment of type 2 diabetes

James Malone MD, Michael Trautmann MD, Ken Wilhelm MD, Kristin Taylor PhD & David M Kendall MD

Pages: 359-367

Published online: 09 May 2009

AbstractforExenatide once weekly for the treatment of type 2 diabetes | Full Text | References | PDF (288.2 KB)

433 Views
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Key Paper Evaluation

Article

Daclizumab a novel corticosteroid-sparing therapy for asthma?

Evaluation of: Busse WW, Israel E, Nelson HS, et al. Daclizumab improves asthma control in patients with moderate to severe persistent asthma: a randomized, controlled trial. Am J Respir Crit Care Med 2008;178:1002-8

Sabina A Antoniu MD PhD

Pages: 369-371

Published online: 09 May 2009

AbstractforDaclizumab a novel corticosteroid-sparing therapy for asthma? | Full Text | References | PDF (197.1 KB)

67 Views
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Meeting Highlights

Article

Highlights of regional meeting of Italian Southern Oncological Group (GOIM): focus on hepatocellular carcinoma: biological and clinical background, therapeutic guide-lines and perspectives

7 November 2008, Naples, Italy

Raffaele Addeo, Michele Caraglia & Salvatore Del Prete

Pages: 373-378

Published online: 09 May 2009

AbstractforHighlights of regional meeting of Italian Southern Oncological Group (GOIM): focus on hepatocellular carcinoma: biological and clinical background, therapeutic guide-lines and perspectives | Full Text | References | PDF (230.8 KB)

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