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Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 20, Issue 3 (2011)

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Expert Opinion on Investigational Drugs, Volume 20, Issue 3 (2011)

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Editorial

Article

The DEFINE study: a bright future for CETP inhibitors?

Niki Katsiki, Vasilios G Athyros & Dimitri P Mikhailidis

Pages: 311-314

Published online: 17 Jan 2011

First Page PreviewforThe DEFINE study: a bright future for CETP inhibitors? | Full Text | References | PDF (160.9 KB)

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Reviews

Article

Statins and dilated cardiomyopathy: do we have enough data?

Agata Bielecka-Dabrowa MD, Dimitri P Mikhailidis MD, Simon Hannam MD, Wilbert S Aronow MD, Jacek Rysz MD & Maciej Banach MD PhD, FESC

Pages: 315-323

Published online: 06 Jan 2011

AbstractforStatins and dilated cardiomyopathy: do we have enough data? | Full Text | References | PDF (198.5 KB)

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Article

Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?

Bruno P Imbimbo PhD, Francesco Panza MD PhD, Vincenza Frisardi MD, Vincenzo Solfrizzi MD PhD, Grazia D'Onofrio PhD, Giancarlo Logroscino MD PhD, Davide Seripa PhD & Alberto Pilotto MD

Pages: 325-341

Published online: 11 Jan 2011

AbstractforTherapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option? | Full Text | References | PDF (376.5 KB)

538 Views
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Article

New nucleoside analogs for patients with hematological malignancies

Tadeusz Robak

Pages: 343-359

Published online: 14 Feb 2011

AbstractforNew nucleoside analogs for patients with hematological malignancies | Full Text | References | PDF (661.3 KB)

538 Views
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Article

Toll-like receptor 9 agonists as cancer therapeutics

Udo Holtick MD, Max E Scheulen, Michael S von Bergwelt-Baildon & Martin R Weihrauch

Pages: 361-372

Published online: 22 Jan 2011

AbstractforToll-like receptor 9 agonists as cancer therapeutics | Full Text | References | PDF (305.1 KB)

663 Views
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Article

The use of vasopressin receptor antagonists in hyponatremia

Elwaleed A Elhassan MD & Robert W Schrier MD

Pages: 373-380

Published online: 14 Feb 2011

AbstractforThe use of vasopressin receptor antagonists in hyponatremia | Full Text | References | PDF (264 KB)

212 Views
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Article

Current and future directions in mammalian target of rapamycin inhibitors development

Angelica Fasolo & Cristiana Sessa

Pages: 381-394

Published online: 08 Feb 2011

AbstractforCurrent and future directions in mammalian target of rapamycin inhibitors development | Full Text | References | PDF (418.3 KB) | Supplemental

659 Views
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Article

Novel IκB kinase inhibitors for treatment of nuclear factor-κB-related diseases

Jun-Ichi Suzuki, Masahito Ogawa, Susumu Muto, Akiko Itai, Mitsuaki Isobe, Yasunobu Hirata & Ryozo Nagai

Pages: 395-405

Published online: 11 Feb 2011

AbstractforNovel IκB kinase inhibitors for treatment of nuclear factor-κB-related diseases | Full Text | References | PDF (334.4 KB)

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Drug Evaluations

Article

XL184 (cabozantinib) for medullary thyroid carcinoma

Cosimo Durante MD, Diego Russo MD, Antonella Verrienti PhD & Sebastiano Filetti MD

Pages: 407-413

Published online: 11 Feb 2011

AbstractforXL184 (cabozantinib) for medullary thyroid carcinoma | Full Text | References | PDF (256 KB)

565 Views
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Article

BIBW 2992 in non-small cell lung cancer

Deepa S Subramaniam & Jimmy Hwang

Pages: 415-422

Published online: 14 Feb 2011

AbstractforBIBW 2992 in non-small cell lung cancer | Full Text | References | PDF (276.1 KB)

450 Views
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Key Paper Evaluation

Article

Cystic fibrosis transmembrane regulator potentiators as promising cystic fibrosis therapies

Evaluation of: Accurso FJ, Rowe SM, Clancy JP, et al. Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation. N Engl J Med 2010;363(21):1991-2003

Sabina Antonela Antoniu MD PhD

Pages: 423-425

Published online: 09 Feb 2011

AbstractforCystic fibrosis transmembrane regulator potentiators as promising cystic fibrosis therapies | Full Text | References | PDF (159.5 KB)

397 Views
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