Expert Opinion on Drug Metabolism & Toxicology, Volume 20, Issue 5 (2024)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 20, Issue 5 (2024)

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Editorial

Editorial
Cephalosporins with warfarin increase the risk of bleeding: myth or fact?
Abrar K. Thabit, Samaher Y. Almoalim & Rahaf Altalhi
Pages: 293-296
Published online: 09 May 2024
First Page PreviewforCephalosporins with warfarin increase the risk of bleeding: myth or fact? | Full Text | References | PDF (1.2 MB) | EPUB
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Drug Evaluation

Review Article
Evaluating the pharmacokinetics of upadacitinib for the treatment of moderate-to-severe Crohn’s disease
Ilaria Faggiani, Ferdinando D’Amico, Francesca Bernardi, Sarah Bencardino, Mariangela Allocca, Federica Furfaro, Tommaso Lorenzo Parigi, Alessandra Zilli, Gionata Fiorino, Laurent Peyrin-Biroulet & Silvio Danese
Pages: 297-305
Published online: 13 May 2024
AbstractforEvaluating the pharmacokinetics of upadacitinib for the treatment of moderate-to-severe Crohn’s disease | Full Text | References | PDF (687.3 KB) | EPUB
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Review

Review Article
Pharmacokinetic considerations for drugs that treat diarrhea-predominant irritable bowel syndrome: what’s new?
Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi
Pages: 307-317
Published online: 02 May 2024
AbstractforPharmacokinetic considerations for drugs that treat diarrhea-predominant irritable bowel syndrome: what’s new? | Full Text | References | PDF (1 MB) | EPUB
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Review Article
Pharmacogenetics in IBS: update and impact of GWAS studies in drug targets and metabolism
Michael Camilleri & Kara Jencks
Pages: 319-332
Published online: 26 May 2024
AbstractforPharmacogenetics in IBS: update and impact of GWAS studies in drug targets and metabolism | Full Text | References | PDF (1.7 MB) | EPUB
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Review Article
Interactions between grapefruit juice and psychotropic medications: an update of the literature and an original case series
Marcin Siwek, Anna Julia Krupa & Jarosław Woroń
Pages: 333-345
Published online: 09 May 2024
AbstractforInteractions between grapefruit juice and psychotropic medications: an update of the literature and an original case series | Full Text | References | PDF (1.4 MB) | EPUB
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Review Article
Optimizing co-prescription of clozapine and antiseizure medications: a systematic review and expert recommendations for clinical practice
Hélène Verdoux, Clélia Quiles & Jose de Leon
Pages: 347-358
Published online: 18 Apr 2024
AbstractforOptimizing co-prescription of clozapine and antiseizure medications: a systematic review and expert recommendations for clinical practice | Full Text | References | PDF (389.1 KB) | EPUB
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Review Article
Interactions between antiepileptic drugs and direct oral anticoagulants for primary and secondary stroke prevention
Claudia Stöllberger, Josef Finsterer & Birke Schneider
Pages: 359-376
Published online: 09 May 2024
AbstractforInteractions between antiepileptic drugs and direct oral anticoagulants for primary and secondary stroke prevention | Full Text | References | PDF (555.2 KB) | EPUB
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Review Article
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review
Yaping Liu, Jiapeng Li & Hao-Jie Zhu
Pages: 377-397
Published online: 06 May 2024
AbstractforRegulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
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Original Research

Article
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches
Ayako Moriyama, Hinata Ueda, Katsuya Narumi, Shuho Asano, Ayako Furugen, Yoshitaka Saito & Masaki Kobayashi
Pages: 399-406
Published online: 09 May 2024
AbstractforContribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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