Current understanding and future perspectives on the extraction, structures, and regulation of muscle function of tea pigments

References

• Aizawa, T., A. Yamamoto, and T. Ueno. 2017. Effect of oral theaflavin administration on body weight, fat, and muscle in healthy subjects: A randomized pilot study. Bioscience, Biotechnology, and Biochemistry 81 (2):311–5. doi: 10.1080/09168451.2016.1246170.[Mismatch]
   PubMed Web of Science ®Google Scholar
• Aoki, Y., T. Ozawa, O. Numata, and T. Takemasa. 2019. High-molecular-weight polyphenol-rich fraction of black tea does not prevent atrophy by unloading, but promotes soleus muscle mass recovery from atrophy in mice. Nutrients 11 (9):2131. doi: 10.3390/nu11092131.
   PubMed Web of Science ®Google Scholar
• Arent, S. M., M. Senso, D. L. Golem, and K. H. McKeever. 2010. The effects of theaflavin-enriched black tea extract on muscle soreness, oxidative stress, inflammation, and endocrine responses to acute anaerobic interval training: A randomized, double-blind, crossover study. Journal of the International Society of Sports Nutrition 7 (1):1–10. doi: 10.1186/1550-2783-7-11.
   PubMedGoogle Scholar
• Bailey, R. G., H. E. Nursten, and I. McDowell. 1992. Isolation and analysis of a polymeric thearubigin fraction from tea. Journal of the Science of Food and Agriculture 59 (3):365–75. doi: 10.1002/jsfa.2740590314.
   Web of Science ®Google Scholar
• Basu, S., T. Chaudhuri, S. P. S. Chauhan, A. K. Das Gupta, L. Chaudhury, and J. R. Vedasiromoni. 2005. The Theaflavin fraction is responsible for the facilitatory effect of black tea at the skeletal myoneural junction. Life Sciences 76 (26):3081–8. doi: 10.1016/j.lfs.2004.12.018.
   PubMed Web of Science ®Google Scholar
• Beaudart, C., M. Zaaria, F. Pasleau, J.-Y. Reginster, and O. Bruyère. 2017. Health outcomes of sarcopenia: A systematic review and meta-analysis. PloS One 12 (1):e0169548. doi: 10.1371/journal.pone.0169548.
   PubMed Web of Science ®Google Scholar
• Bonnely, S., A. L. Davis, J. R. Lewis, and C. Astill. 2003. A model oxidation system to study oxidised phenolic compounds present in black tea. Food Chemistry 83 (4):485–92. doi: 10.1016/S0308-8146(03)00129-8.
   Web of Science ®Google Scholar
• Brown, A. G., W. B. Eyton, A. Holmes, and W. D. Ollis. 1969. The identification of the thearubigins as polymeric proanthocyanidins. Phytochemistry 8 (12):2333–40. doi: 10.1016/S0031-9422(00)88151-0.
   Web of Science ®Google Scholar
• Burton, L. A., D. Sumukadas, M. D. Witham, A. D. Struthers, and M. E. T. McMurdo. 2013. Effect of spironolactone on physical performance in older people with self-reported physical disability. The American Journal of Medicine 126 (7):590–7. doi: 10.1016/j.amjmed.2012.11.032.
   PubMed Web of Science ®Google Scholar
• Cao, Y., W. Sun, and G. Xu. 2019. Fuzhu Jiangtang granules combined with metformin reduces insulin resistance in skeletal muscle of diabetic rats via PI3K/Akt signaling. Pharmaceutical Biology 57 (1):660–8. doi: 10.1080/13880209.2019.1659831.
   PubMed Web of Science ®Google Scholar
• Cattell, D. J., and H. E. Nursten. 1977. Separation of thearubigins on sephadex LH-20. Phytochemistry 16 (8):1269–72. doi: 10.1016/S0031-9422(00)94372-3.
   Web of Science ®Google Scholar
• Chang, L., X. Liu, J. Liu, H. Li, Y. Yang, J. Liu, Z. Guo, K. Xiao, C. Zhang, J. Liu, et al. 2014. D-Galactose induces a mitochondrial complex i deficiency in mouse skeletal muscle: Potential benefits of nutrient combination in ameliorating muscle impairment. Journal of Medicinal Food 17 (3):357–64. doi: 10.1089/jmf.2013.2830.
   PubMed Web of Science ®Google Scholar
• Collins, C. A., and T. A. Partridge. 2005. Self-renewal of the adult skeletal muscle satellite cell. Cell Cycle (Georgetown, Tex.) 4 (10):1338–41. doi: 10.4161/cc.4.10.2114.
   PubMed Web of Science ®Google Scholar
• Davies, A., C. Goodsall, Y. Cai, A. Davis, J. Lewis, J. Wilkins, X. Wan, M. N. Clifford, C. Powell, A. Parry, et al. 1999. Black tea dimeric and oligomeric pigments—Structures and formation. Plant Polyphenols 2:697–724. doi: 10.1007/978-1-4615-4139-4_39.
   Google Scholar
• Degenhardt, A., U. H. Engelhardt, A.-S. Wendt, and P. Winterhalter. 2000. Isolation of black tea pigments using high-speed countercurrent chromatography and studies on properties of black tea polymers. Journal of Agricultural and Food Chemistry 48 (11):5200–5. doi: 10.1021/jf000757+.
   PubMed Web of Science ®Google Scholar
• Degenhardt, A., U. H. Engelhardt, P. Winterhalter, and Y. Ito. 2001. Centrifugal precipitation chromatography: A novel chromatographic system for fractionation of polymeric pigments from black tea and red wine. Journal of Agricultural and Food Chemistry 49 (4):1730–6. doi: 10.1021/jf0010580.
   PubMed Web of Science ®Google Scholar
• Ding, Y. P., L. Q. Zou, C. Q. Lu, H. R. Tong, and B. C. Chen. 2018. In situ enzymatic synthesis and purification of theaflavin-3,3’-digallate monomer and incorporation into nanoliposome. International Journal of Food Science & Technology 53 (11):2552–9. doi: 10.1111/ijfs.13849.
   Web of Science ®Google Scholar
• Dodds, R. M., A. Granic, K. Davies, T. B. L. Kirkwood, C. Jagger, and A. A. Sayer. 2017. Prevalence and incidence of sarcopenia in the very old: findings from the Newcastle 85+ study. Journal of Cachexia, Sarcopenia and Muscle 8 (2):229–37. doi: 10.1002/jcsm.12157.
   PubMed Web of Science ®Google Scholar
• Dong, W. M., T. Chao, and J. S. Gong. 2013. Factors influencing the effects of theabrownin in pu-erh tea on scavenging DPPH radicals. Agricultural Science & Technology 14 (2):317–23. doi: 10.16175/j.cnki.1009-4229.2013.02.005.
   Google Scholar
• Doma, K., D. Gahreman, A. K. Ramachandran, U. Singh, and J. Connor. 2021. The effect of leaf extract supplementation on exercise-induced muscle damage and muscular performance: A systematic review and meta-analysis. Journal of Sports Sciences 39 (17):1952–68. doi: 10.1080/02640414.2021.1911050.
   PubMed Web of Science ®Google Scholar
• Dreger, H., M. Lorenz, A. Kehrer, G. Baumann, K. Stangl, and V. Stangl. 2008. Characteristics of catechin- and theaflavin-mediated cardioprotection. Experimental Biology and Medicine (Maywood, N.J.) 233 (4):427–33. doi: 10.3181/0710-RM-292.
   PubMed Web of Science ®Google Scholar
• Du, Q., H. Jiang, and Y. Ito. 2001. Separation of theaflavins of black tea. high-speed countercurrent chromatography vs. sephadex LH-20 gel column chromatography. Journal of Liquid Chromatography & Related Technologies 24 (15):2363–9. doi: 10.1081/JLC-100105147.
   Web of Science ®Google Scholar
• Eguchi, T., C. Kumagai, T. Fujihara, T. Takemasa, T. Ozawa, and O. Numata. 2013. Black tea high-molecular-weight polyphenol stimulates exercise training-induced improvement of endurance capacity in mouse via the link between AMPK and GLUT4. PloS One 8 (7):e69480. doi: 10.1371/journal.pone.0069480.
   PubMed Web of Science ®Google Scholar
• Fu, Y., S. Li, H. Tong, S. Li, and Y. Yan. 2019. WDR13 promotes the differentiation of bovine skeletal muscle-derived satellite cells by affecting PI3K/AKT signaling. Cell Biology International 43 (7):799–808. doi: 10.1002/cbin.11160.
   PubMed Web of Science ®Google Scholar
• Fujihara, T., A. Nakagawa-Izumi, T. Ozawa, and O. Numata. 2007. High-molecular-weight polyphenols from oolong tea and black tea: Purification, some properties, and role in increasing mitochondrial membrane potential. Bioscience, Biotechnology, and Biochemistry 71 (3):711–9. doi: 10.1271/bbb.60562.
   PubMed Web of Science ®Google Scholar
• Gong, J. S., C. X. Peng, T. Chen, B. Gao, and H. J. Zhou. 2010. Effects of theabrownin from Pu-Erh tea on the metabolism of serum lipids in rats: Mechanism of action. Journal of Food Science 75 (6):H182–189. doi: 10.1111/j.1750-3841.2010.01675.x.
   PubMed Web of Science ®Google Scholar
• Gong, J., Q. Zhang, C. Peng, J. Fan, and W. Dong. 2012. Curie-point pyrolysis–gas chromatography–mass spectroscopic analysis of theabrownins from fermented Zijuan tea. Journal of Analytical and Applied Pyrolysis 97:171–80. doi: 10.1016/j.jaap.2012.06.004.
   Web of Science ®Google Scholar
• Halder, J., and A. N. Bhaduri. 1998. Protective role of black tea against oxidative damage of human red blood cells. Biochemical and Biophysical Research Communications 244 (3):903–7. doi: 10.1006/bbrc.1998.8366.
   PubMed Web of Science ®Google Scholar
• Haslam, E. 2003. Thoughts on thearubigins. Phytochemistry 64 (1):61–73. doi: 10.1016/S0031-9422(03)00355-8.
   PubMed Web of Science ®Google Scholar
• Hazarika, M., S. K. Chakravarty, and P. K. Mahanta. 1984. Studies on thearubigin pigments in black tea manufacturing systems. Journal of the Science of Food and Agriculture 35 (11):1208–18. doi: 10.1002/jsfa.2740351112.
   Web of Science ®Google Scholar
• He, Y., X. Wang, and X. Zhang. 2013. Study on extracting TB from Liubao Tea with cellulase auxiliary method. Advanced Materials Research 781-784+:1870–4. doi: 10.4028/www.scientific.net/AMR.781-784.1870.
   Google Scholar
• Herrlinger, K. A., D. M. Chirouzes, and M. A. Ceddia. 2015. Supplementation with a polyphenolic blend improves post-exercise strength recovery and muscle soreness. Food & Nutrition Research 59:30034. doi: 10.3402/fnr.v59.30034.
   PubMed Web of Science ®Google Scholar
• Horgan, F. G., A. Peñalver Cruz, C. C. Bernal, A. F. Ramal, M. L. P. Almazan, and A. Wilby. 2018. Resistance and tolerance to the brown planthopper, Nilaparvata lugens (Stål), in rice infested at different growth stages across a gradient of nitrogen applications. Field Crops Research 217:53–65. doi: 10.1016/j.fcr.2017.12.008.
   PubMed Web of Science ®Google Scholar
• Huang, F., X. Zheng, X. Ma, R. Jiang, W. Zhou, S. Zhou, Y. Zhang, S. Lei, S. Wang, J. Kuang, et al. 2019. Theabrownin from Pu-Erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism. Nature Communications 10 (1):4971. doi: 10.1038/s41467-019-12896-x.
   PubMedGoogle Scholar
• Huang, Y., Y. Wei, J. Xu, and X. We. 2022. A comprehensive review on the prevention and regulation of Alzheimer’s disease by tea and its active ingredients. Critical Reviews in Food Science and Nutrition 1–26. doi: 10.1080/10408398.2022.2081128. PMID: 35647742
   Web of Science ®Google Scholar
• Kemmler, W., M. Teschler, S. Goisser, M. Bebenek, S. von Stengel, L. C. Bollheimer, C. C. Sieber, and E. Freiberger. 2015. Prevalence of sarcopenia in Germany and the corresponding effect of osteoarthritis in females 70 years and older living in the community: Results of the FORMoSA study. Clinical Interventions in Aging 10:1565–73. doi: 10.2147/CIA.S89585.
   PubMed Web of Science ®Google Scholar
• Kuriyama, S., T. Shimazu, K. Ohmori, N. Kikuchi, N. Nakaya, Y. Nishino, Y. Tsubono, and I. Tsuji. 2006. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: The Ohsaki Study. JAMA 296 (10):1255–65. doi: 10.1001/jama.296.10.1255.
   PubMed Web of Science ®Google Scholar
• Krishnan, R., and G. B. Maru. 2006. Isolation and analyses of polymeric polyphenol fractions from black tea. Food Chemistry 94 (3):331–40. doi: 10.1016/j.foodchem.2004.11.039.
   Web of Science ®Google Scholar
• Kudo, N., Y. Arai, Y. Suhara, T. Ishii, T. Nakayama, and N. Osakabe. 2015. A single oral Administration of theaflavins increases energy expenditure and the expression of metabolic genes. PloS One 10 (9):e0137809. doi: 10.1371/journal.pone.0137809.
   PubMed Web of Science ®Google Scholar
• Kuhnert, N. 2010. Unraveling the structure of the black tea thearubigins. Archives of Biochemistry and Biophysics 501 (1):37–51. doi: 10.1016/j.abb.2010.04.013.
   PubMed Web of Science ®Google Scholar
• Kuhnert, N., J. W. Drynan, J. Obuchowicz, M. N. Clifford, and M. Witt. 2010. Mass spectrometric characterization of black tea thearubigins leading to an oxidative cascade hypothesis for thearubigin formation. Rapid Communications in Mass Spectrometry : RCM 24 (23):3387–404. doi: 10.1002/rcm.4778.
   PubMed Web of Science ®Google Scholar
• Lea, A. G. H., and D. J. Crispin. 1971. The separation of theaflavins on sephadex LH-20. Journal of Chromatography A 54:133–5. doi: 10.1016/S0021-9673(01)80255-7.
   Web of Science ®Google Scholar
• Li, B., S. B. Vik, and Y. Tu. 2012. Theaflavins inhibit the ATP synthase and the respiratory chain without increasing superoxide production. The Journal of Nutritional Biochemistry 23 (8):953–60. doi: 10.1016/j.jnutbio.2011.05.001.
   PubMed Web of Science ®Google Scholar
• Li, B. C., J. S. Gao, H. F. Zhang, Z. Li, W. F. Dai, and X. C. Zeng. 2007. Humic acid and pigments of Pu-Erh tea. Humic Acid 1:19–26. doi: 10.3969/j.issn.1671-9212.2007.01.004.
   Google Scholar
• Li, D., C. Yang, Y. Chen, J. Tian, L. Liu, Q. Dai, X. Wan, and Z. Xie. 2008. Identification of a PKCε-dependent regulation of myocardial contraction by epicatechin-3-gallate. American Journal of Physiology. Heart and Circulatory Physiology 294 (1):H345–353. doi: 10.1152/ajpheart.00785.2007.
   PubMed Web of Science ®Google Scholar
• Li, P., A. Liu, W. Xiong, H. Lin, W. Xiao, J. Huang, S. Zhang, and Z. Liu. 2020. Catechins enhance skeletal muscle performance. Critical Reviews in Food Science and Nutrition 60 (3):515–28. doi: 10.1080/10408398.2018.1549534.
   PubMed Web of Science ®Google Scholar
• Lin, F. J., X. L. Wei, H. Y. Liu, H. Li, Y. Xia, D. T. Wu, P. Z. Zhang, G. R. Gandhi, H. B. Li, and R. Y. Gan. 2021. State-of-the-art review of dark tea: From chemistry to health benefits. Trends in Food Science & Technology 109:126–38. doi: 10.1016/j.tifs.2021.01.030.
   Web of Science ®Google Scholar
• Lodovici, M., C. Casalini, C. D. Filippo, E. Copeland, X. Xu, M. Clifford, and P. Dolara. 2000. Inhibition of 1,2-dimethylhydrazine-induced oxidative DNA damage in rat colon mucosa by black tea complex polyphenols. Food and Chemical Toxicology 38 (12):1085–8. doi: 10.1016/S0278-6915(00)00109-5.
   PubMed Web of Science ®Google Scholar
• Lu, H., P. Yue, Y. Wang, and X. Gao. 2016. Study of bioactive components and color properties of dark tea infusion manufactured by Eurotium cristatum using submerged fermentation. Advance Journal of Food Science and Technology 10 (8):591–6. doi: 10.19026/ajfst.10.2189.
   Google Scholar
• Łuczaj, W., and E. Skrzydlewska. 2005. Antioxidative properties of black tea. Preventive Medicine 40 (6):910–8. doi: 10.1016/j.ypmed.2004.10.014.
   PubMed Web of Science ®Google Scholar
• Luo, D., X. Chen, X. Zhu, S. Liu, J. Li, J. Xu, J. Zhao, and X. Ji. 2019. Pu-Erh tea relaxes the thoracic aorta of rats by reducing intracellular calcium. Frontiers in Pharmacology 10:1430. doi: 10.3389/fphar.2019.01430.
   PubMed Web of Science ®Google Scholar
• Lv, H., Y. Zhang, J. Shi, and Z. Lin. 2017. Phytochemical profiles and antioxidant activities of chinese dark teas obtained by different processing technologies. Food Research International (Ottawa, Ont.) 100 (Pt 3):486–93. doi: 10.1016/j.foodres.2016.10.024.
   PubMedGoogle Scholar
• Ma, H., X. Huang, Q. Li, Y. Guan, F. Yuan, and Y. Zhang. 2011. ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat. The Journal of Physiological Sciences 61 (4):337–42. doi: 10.1007/s12576-011-0148-9.
   PubMed Web of Science ®Google Scholar
• McDowell, I., S. Taylor, and C. Gay. 1995. The phenolic pigment composition of black tea liquors—part i: Predicting quality. Journal of the Science of Food and Agriculture 69 (4):467–74. doi: 10.1002/jsfa.2740690411.
   Web of Science ®Google Scholar
• Melov, S., J. M. Shoffner, A. Kaufman, and D. C. Wallace. 1995. Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle. Nucleic Acids Research 23 (20):4122–6. doi: 10.1093/nar/23.20.4122.
   PubMed Web of Science ®Google Scholar
• Menet, M.-C., S. Sang, C. S. Yang, C.-T. Ho, and R. T. Rosen. 2004. Analysis of theaflavins and thearubigins from black tea extract by MALDI-TOF mass spectrometry. Journal of Agricultural and Food Chemistry 52 (9):2455–61. doi: 10.1021/jf035427e.
   PubMed Web of Science ®Google Scholar
• Millin, D., D. Swaine, and P. Dix. 1969. Separation and classification of aqueous infused brown pigments of black tea. Journal of the Science of Food and Agriculture 20 (5):296–302. doi: 10.1002/jsfa.2740200511.
   Web of Science ®Google Scholar
• Miyata, Y., T. Tanaka, K. Tamaya, T. Matsui, S. Tamaru, and K. Tanaka. 2011. Cholesterol-lowering effect of black tea polyphenols, theaflavins, theasinensin a and thearubigins, in rats fed high fat diet. Food Science and Technology Research 17 (6):585–8. doi: 10.3136/fstr.17.585.
   Web of Science ®Google Scholar
• Morley, J. E. 1997. Anorexia of aging: Physiologic and pathologic. The American Journal of Clinical Nutrition 66 (4):760–73. doi: 10.1093/ajcn/66.4.760.
   PubMed Web of Science ®Google Scholar
• Nagano, T., K. Hayashibara, M. Ueda-Wakagi, Y. Yamashita, and H. Ashida. 2015. Black tea polyphenols promotes GLUT4 translocation through both PI3K-and AMPK-dependent pathways in skeletal muscle cells. Food Science and Technology Research 21 (3):489–94. doi: 10.3136/fstr.21.489.
   Web of Science ®Google Scholar
• Narai-Kanayama, A., Y. Uchida, A. Kawashima, and T. Nakayama. 2019. Elimination of hydrogen peroxide enhances tyrosinase-catalyzed synthesis of theaflavins. Process Biochemistry 85:19–28. doi: 10.1016/j.procbio.2019.07.004.
   Web of Science ®Google Scholar
• Narai-Kanayama, A., Y. Uekusa, F. Kiuchi, and T. Nakayama. 2018. Efficient synthesis of theaflavin 3-gallate by a tyrosinase-catalyzed reaction with (−)-epicatechin and (−)-epigallocatechin gallate in a 1-octanol/buffer biphasic system. Journal of Agricultural and Food Chemistry 66 (51):13464–72. doi: 10.1021/acs.jafc.8b05971.
   PubMed Web of Science ®Google Scholar
• Ngure, F. M., J. K. Wanyoko, S. M. Mahungu, and A. A. Shitandi. 2009. Catechins depletion patterns in relation to theaflavin and thearubigins formation. Food Chemistry 115 (1):8–14. doi: 10.1016/j.foodchem.2008.10.006.
   Web of Science ®Google Scholar
• Oh, J.-E., Y. J. Lee, Y.-W. Kim, S.-Y. Park, K.-M. Lee, and J.-Y. Kim. 2009. The effect of black tea on biomarkers of metabolic syndrome in high fat diet fed rats. Journal of the Korean Society for Applied Biological Chemistry 52 (2):193–7. doi: 10.3839/jksabc.2009.035.
   Google Scholar
• Ozawa, T., M. Kataoka, K. Morikawa, and O. Negishi. 1996. Elucidation of the partial structure of polymeric thearubigins from black tea by chemical degradation. Bioscience, Biotechnology and Biochemistry 60 (12):2023–7. doi: 10.1271/bbb.60.2023.
   PubMed Web of Science ®Google Scholar
• Peng, C., J. Liu, H. Liu, H. Zhou, and J. Gong. 2013. Influence of different fermentation raw materials on pyrolyzates of Pu-Erh tea theabrownin by curie-point pyrolysis-gas chromatography–mass spectroscopy. International Journal of Biological Macromolecules 54:197–203. doi: 10.1016/j.ijbiomac.2012.12.021.
   PubMed Web of Science ®Google Scholar
• Peng, C. X., L. Jian, H. R. Liu, H. J. Zhou, and J. S. Gong. 2013. Influence of different fermentation raw materials on pyrolyzates of Pu-erh tea theabrownin by Curie-point pyrolysis-gas chromatography–mass spectroscopy. International Journal of Biological Macromolecules 54 (1):197–203. doi: 10.1016/j.ijbiomac.2012.12.021.
   PubMedGoogle Scholar
• Peng, C. X., Q. P. Wang, H. R. Liu, B. Gao, J. Sheng, and J. S. Gong. 2013. Effects of Zijuan pu-erh tea theabrownin on metabolites in hyperlipidemic rat feces by Py-GC/MS. Journal of Analytical and Applied Pyrolysis 104:226–33. doi: 10.1016/j.jaap.2013.07.011.
   Web of Science ®Google Scholar
• Powell, C., M. N. Clifford, S. C. Opie, M. A. Ford, A. Robertson, and C. L. Gibson. 1993. Tea cream formation: The contribution of black tea phenolic pigments determined by HPLC. Journal of the Science of Food and Agriculture 63 (1):77–86. doi: 10.1002/jsfa.2740630113.
   Web of Science ®Google Scholar
• Proestos, C., and M. Komaitis. 2008. Application of microwave-assisted extraction to the fast extraction of plant phenolic compounds. LWT - Food Science and Technology 41 (4):652–9. doi: 10.1016/j.lwt.2007.04.013.
   Web of Science ®Google Scholar
• Qu, Z., A. Liu, C. Liu, Q. Tang, L. Zhan, W. Xiao, J. Huang, Z. Liu, and S. Zhang. 2021. Theaflavin promotes mitochondrial abundance and glucose absorption in myotubes by activating the CaMKK2-AMPK signal axis via calcium-ion influx. Journal of Agricultural and Food Chemistry 69 (29):8144–59. doi: 10.1021/acs.jafc.1c02892.
   PubMed Web of Science ®Google Scholar
• Qu, Z., C. Liu, P. Li, W. Xiong, Z. Zeng, A. Liu, W. Xiao, J. Huang, Z. Liu, and S. Zhang. 2020. Theaflavin promotes myogenic differentiation by regulating the cell cycle and surface mechanical properties of C2C12 cells. Journal of Agricultural and Food Chemistry 68 (37):9978–92. doi: 10.1021/acs.jafc.0c03744.
   PubMed Web of Science ®Google Scholar
• Roberts, E. A. H. 1958. The phenolic substances of manufactured tea. II. — Their origin as enzymic oxidation products in fermentation. Journal of the Science of Food and Agriculture 9 (4):212–6. doi: 10.1002/jsfa.2740090405.
   Google Scholar
• Roberts, E. A. H., and M. Myers. 1959. The phenolic substances of manufactured tea. VI.–The preparation of theaflavin and of theaflavin gallate. Journal of the Science of Food and Agriculture 10 (3):176–9. doi: 10.1002/jsfa.2740100305.
   Google Scholar
• Roberts, E. A. H., and R. F. Smith. 1963. The phenolic substances of manufactured tea. IX.—The Spectrophotometric evaluation of tea liquors. Journal of the Science of Food and Agriculture 14 (10):689–700. doi: 10.1002/jsfa.2740141002.
   Web of Science ®Google Scholar
• Robertson, A., and D. S. Bendall. 1983. Production and HPLC analysis of black tea theaflavins and thearubigins during in vitro oxidation. Phytochemistry 22 (4):883–7. doi: 10.1016/0031-9422(83)85016-X.
   Web of Science ®Google Scholar
• Sang, S. M., S. Y. Tian, J. W. Jhoo, H. Wang, R. E. Stark, R. T. Rosen, C. S. Yang, and C. T. Ho. 2003. Chemical studies of the antioxidant mechanism of theaflavins: Radical reaction products of theaflavin 3,3′-digallate with hydrogen peroxide. Tetrahedron Letters 44 (30):5583–7. doi: 10.1016/S0040-4039(03)01382-0.
   Web of Science ®Google Scholar
• Seo, H., S.-H. Lee, Y. Park, H.-S. Lee, J. S. Hong, C. Y. Lim, D. H. Kim, S.-S. Park, H. J. Suh, and K.-B. Hong. 2021. (−)-Epicatechin-enriched extract from Camellia sinensis improves regulation of muscle mass and function: Results from a randomized controlled trial. Antioxidants 10 (7):1026. doi: 10.3390/antiox10071026.
   Web of Science ®Google Scholar
• Shan, Z., M. F. Nisar, M. Li, C. Zhang, and C. Wan. 2021. Theaflavin Chemistry and Its Health Benefits. Oxidative Medicine and Cellular Longevity 2021:1–16. doi: 10.1155/2021/6256618.
   Web of Science ®Google Scholar
• Shen, Z., Q. Chen, T. Jin, M. Wang, H. Ying, J. Lu, M. Wang, W. Zhang, F. Qiu, C. Jin, et al. 2019. Theaflavin 3,3′-digallate reverses the downregulation of connexin 43 and autophagy induced by high glucose via AMPK activation in cardiomyocytes. Journal of Cellular Physiology 234 (10):17999–8016. doi: 10.1002/jcp.28432.
   PubMed Web of Science ®Google Scholar
• Stodt, U. W., J. Stark, and U. H. Engelhardt. 2015. Comparison of three strategies for the isolation of black tea thearubigins with a focus on countercurrent chromatography. Journal of Food Composition and Analysis 43:160–8. doi: 10.1016/j.jfca.2015.07.002.
   Web of Science ®Google Scholar
• Suzuki, K., N. Hirashima, Y. Fujii, T. Fushimi, A. Yamamoto, T. Ueno, R. Akagi, and N. Osakabe. 2021. Theaflavins decrease skeletal muscle wasting in disuse atrophy induced by hindlimb suspension in mice. Journal of Clinical Biochemistry and Nutrition 68 (3):228–7. doi: 10.3164/jcbn.20-68.
   PubMed Web of Science ®Google Scholar
• Takemoto, M., H. Takemoto, and A. Sakurada. 2014. Synthesis of theaflavins with Camellia sinensis cell culture and inhibition of increase in blood sugar values in high-fat diet mice subjected to sucrose or glucose loading. Tetrahedron Letters 55 (36):5038–540. doi: 10.1016/j.tetlet.2014.07.092.
   Web of Science ®Google Scholar
• Tan, C., C. X. Peng, B. Gao, and J. S. Gong. 2012. Spectroscopic and structural characteristics of the main components of theabrownin in Pu-Erh tea. Guang pu xue yu guang pu fen xi = Guang pu 32 (4):1051–6. doi: 10.3964/j.issn.1000-0593(2012)04-1051-06.
   PubMedGoogle Scholar
• Tanaka, T., C. Mine, K. Inoue, M. Matsuda, and I. Kouno. 2002. Synthesis of theaflavin from epicatechin and epigallocatechin by plant homogenates and role of epicatechin quinone in the synthesis and degradation of theaflavin. Journal of Agricultural and Food Chemistry 50 (7):2142–8. doi: 10.1021/jf011301a.
   PubMed Web of Science ®Google Scholar
• Teng, J., Z. Gong, Y. Deng, L. Chen, Q. Li, Y. Shao, L. Lin, and W. Xiao. 2017. Purification, characterization and enzymatic synthesis of theaflavins of polyphenol oxidase isozymes from tea leaf (Camellia sinensis). LWT 84:263–70. doi: 10.1016/j.lwt.2017.05.065.
   Web of Science ®Google Scholar
• Tokuda, Y., and H. Mori. 2021. Effect of ingestion of essential amino acids and tea catechins after resistance exercise on the muscle mass, physical performance, and quality of life of healthy older people: A randomized controlled trial. Asia Pacific Journal of Clinical Nutrition 30 (2):213–23. doi: 10.6133/apjcn.202106_30(2).0005.
   PubMed Web of Science ®Google Scholar
• Townsend, J. R., J. R. Stout, A. R. Jajtner, D. D. Church, K. S. Beyer, J. J. Riffe, T. W. D. Muddle, K. L. Herrlinger, D. H. Fukuda, and J. R. Hoffman. 2018. Polyphenol supplementation alters intramuscular apoptotic signaling following acute resistance exercise. Physiological Reports 6 (2):e13552. doi: 10.14814/phy2.13552.
   PubMedGoogle Scholar
• Tsai, T. W., C. C. Chang, S. F. Liao, Y. H. Liao, C. W. Hou, J. P. Tsao, and I. S. Cheng. 2017. Effect of green tea extract supplementation on glycogen replenishment in exercised human skeletal muscle. British Journal of Nutrition 117 (10):1343–50. doi: 10.1017/S0007114517001374.
   PubMed Web of Science ®Google Scholar
• van Loon, L. J. C. 2004. Use of intramuscular triacylglycerol as a substrate source during exercise in humans. Journal of Applied Physiology (Bethesda, Md.: 1985) 97 (4):1170–87. doi: 10.1152/japplphysiol.00368.2004.
   PubMed Web of Science ®Google Scholar
• Vuataz, L., and H. Brandenberger. 1961. Plant phenols: III. Separation of fermented and black tea polyphenols by cellulose column chromatography. Journal of Chromatography A 5:17–31. doi: 10.1016/S0021-9673(01)92812-2.
   Web of Science ®Google Scholar
• Wang, K., Q. Chen, Y. Lin, S. Li, H. Lin, J. Huang, and Z. Liu. 2014. Comparison of phenolic compounds and taste of Chinese black tea. Food Science and Technology Research 20 (3):639–46. doi: 10.3136/fstr.20.639.
   Web of Science ®Google Scholar
• Wang, Q., J. Gong, Y. Chisti, and S. Sirisansaneeyakul. 2014. Bioconversion of tea polyphenols to bioactive theabrownins by Aspergillus fumigatus. Biotechnology Letters 36 (12):2515–22. doi: 10.1007/s10529-014-1632-0.
   PubMed Web of Science ®Google Scholar
• Wang, Q. P., J. S. Gong, Y. Chisti, and S. Sirisansaneeyakul. 2015. Fungal isolates from a Pu-Erh type tea fermentation and their ability to convert tea polyphenols to theabrownins. Journal of Food Science 80 (4):M809–M817. doi: 10.1111/1750-3841.12831.
   PubMed Web of Science ®Google Scholar
• Wang, W., S. Zhang, L. Lv, and S. Sang. 2018. A new method to prepare and redefine black tea thearubigins. Journal of Chromatography. A 1563:82–8. doi: 10.1016/j.chroma.2018.05.060.
   PubMed Web of Science ®Google Scholar
• Wang, Y., A. Zhao, H. Du, Y. Liu, B. Qi, and X. Yang. 2021. Theabrownin from Fu brick tea exhibits the thermogenic function of adipocytes in high-fat-diet-induced obesity. Journal of Agricultural and Food Chemistry 69 (40):11900–11. doi: 10.1021/acs.jafc.1c04626.
   PubMed Web of Science ®Google Scholar
• Wei, Y., J. Xu, S. Miao, K. Wei, L. Peng, Y. Wang, and X. Wei. 2022. Recent advances in the utilization of tea active ingredients to regulate sleep through neuroendocrine pathway, immune system and intestinal microbiota. Critical Reviews in Food Science and Nutrition :1–2048319. doi: 10.1080/10408398.2022.2048291.
   Web of Science ®Google Scholar
• Wilting, J., B. Brand-Saberi, R. Huang, Q. Zhi, G. Köntges, C. P. Ordahl, and B. Christ. 1995. Angiogenic potential of the avian somite. Developmental Dynamics: An Official Publication of the American Association of Anatomists 202 (2):165–71. doi: 10.1002/aja.1002020208.
   PubMed Web of Science ®Google Scholar
• Wood, W. M., S. Etemad, M. Yamamoto, and D. J. Goldhamer. 2013. MyoD-expressing progenitors are essential for skeletal myogenesis and satellite cell development. Developmental Biology 384 (1):114–27. doi: 10.1016/j.ydbio.2013.09.012.
   PubMed Web of Science ®Google Scholar
• Wu, Y. Y., W. Li, X. Yi, E. H. Jin, and Y. Y. Tu. 2011. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses. Journal of Zhejiang University. Science. B 12 (9):744–51. doi: 10.1631/jzus.B1100041.
   PubMed Web of Science ®Google Scholar
• Xiao, Y., M. Li, Y. Wu, K. Zhong, and H. Gao. 2020. Structural characteristics and hypolipidemic activity of theabrownins from dark tea fermented by single species PW-1. Biomolecules 10 (2):204. doi: 10.3390/biom10020204.
   PubMed Web of Science ®Google Scholar
• Xie, G., M. Ye, Y. Wang, Y. Ni, M. Su, H. Huang, M. Qiu, A. Zhao, X. Zheng, T. Chen, et al. 2009. Characterization of Pu-Erh tea using chemical and metabolic profiling approaches. Journal of Agricultural and Food Chemistry 57 (8):3046–54. doi: 10.1021/jf804000y.
   PubMed Web of Science ®Google Scholar
• Xu, Y., Y. Jin, Y. Wu, and Y. Tu. 2010. Isolation and purification of four individual theaflavins using semi-preparative high performance liquid chromatography. Journal of Liquid Chromatography & Related Technologies 33 (20):1791–801. doi: 10.1080/10826076.2010.526865.
   Web of Science ®Google Scholar
• Yanase, E., K. Sawaki, and S. Nakatsuka. 2005. The isolation of a bicyclo[3.2.1] intermediate during formation of benzo­tropolones, a common nucleus found in black tea pigments: Theaflavins. Synlett 2005 (17):2661–3. doi: 10.1055/s-2005-917094.
   Google Scholar
• Yang, C., D. Li, and X. Wan. 2008. Combination of HSCCC and Sephadex LH-20 methods: An approach to isolation and purification of the main individual theaflavins from black tea. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 861 (1):140–4. doi: 10.1016/j.jchromb.2007.11.022.
   PubMed Web of Science ®Google Scholar
• Yang, L., Y. Xi, X.-Y. Luo, H. Ni, and H.-H. Li. 2019. Preparation of peroxidase and phenolics using discarded sweet potato old stems. Scientific Reports 9 (1):3769. doi: 10.1038/s41598-019-40568-9.
   PubMedGoogle Scholar
• Yang, X. H., L. L. Wang, J. A. Huang, W. U. Wen-Liang, and Z. H. Liu. 2011. Preliminary study on fractions and correlative properties of theabrownin from Pu-Erh Tea. Journal of Tea Science 31 (3):187–94. doi: 10.1097/RLU.0b013e3181f49ac7.
   Google Scholar
• Yang, Z., Y. Tu, H. Xia, G. Jie, X. Chen, and P. He. 2007. Suppression of free-radicals and protection against H2O2-induced oxidative damage in HPF-1 cell by oxidized phenolic compounds present in black tea. Food Chemistry 105 (4):1349–56. doi: 10.1016/j.foodchem.2007.05.006.
   Web of Science ®Google Scholar
• Yassin, G. H., C. Grun, J. H. Koek, K. I. Assaf, and N. Kuhnert. 2014. Investigation of isomeric flavanol structures in black tea thearubigins using ultraperformance liquid chromatography coupled to hybrid quadrupole/ion mobility/time of flight mass spectrometry. Journal of Mass Spectrometry : JMS 49 (11):1086–95. doi: 10.1002/jms.3406.
   PubMed Web of Science ®Google Scholar
• Yassin, G. H., J. H. Koek, and N. Kuhnert. 2014. Identification of trimeric and tetrameric flavan-3-Ol derivatives in the SII black tea thearubigin fraction of black tea using ESI-tandem and MALDI-TOF mass spectrometry. Food Research International 63:317–27. doi: 10.1016/j.foodres.2014.04.010.
   Web of Science ®Google Scholar
• Yu, W., W. Zha, H. Peng, Q. Wang, S. Zhang, and J. F. Ren. 2019. Trehalose protects against insulin resistance-induced tissue injury and excessive autophagy in skeletal muscles and kidney. Current Pharmaceutical Design 25 (18):2077–85. doi: 10.2174/1381612825666190708221539.
   PubMed Web of Science ®Google Scholar
• Zhao, Y. P., W. L. Yu, D. P. Wang, X. F. Liang, and T. X. Hu. 2003. Chemiluminescence determination of free radical scavenging abilities of “tea pigments” and comparison with “tea polyphenols. Food Chemistry 80 (1):115–8. doi: 10.1016/S0308-8146(02)00241-8.
   Web of Science ®Google Scholar
• Zhang, Q., L. X. Dong, G. Q. Li, and J. S. Gong. 2012. Study on membrane separation and its physicochemical properties of theabrownin in “Zijuan” Pu-Erh tea. Journal of Tea Science 3:189–96. doi: 10.13305/j.cnki.jts.2012.03.003.
   Google Scholar
• Zhang, S. H., L. Qian, H. Y. Zhao, and X. F. Lin. 2012. Study on the microwave-assisted extraction method of theabrownine from Pu-Erh tea. Journal of Anhui Agricultural Sciences 40 (22):11421–2. doi: 10.13989/j.cnki.0517-6611.2012.22.050.
   Google Scholar
• Zheng, R., S. Huang, J. Zhu, W. Lin, H. Xu, and X. Zheng. 2019. Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/MTOR signaling pathway in rotator cuff tears. Cell and Tissue Research 378 (1):113–25. doi: 10.1007/s00441-019-03021-x.
   PubMed Web of Science ®Google Scholar
• Zhu, K., J. Ouyang, J. Huang, and Z. Liu. 2021. Research progress of black tea thearubigins: A review. Critical Reviews in Food Science and Nutrition 61 (9):1556–66. doi: 10.1080/10408398.2020.1762161.
   PubMed Web of Science ®Google Scholar
• Zierath, J. R., and Y. Kawano. 2003. The effect of hyperglycaemia on glucose disposal and insulin signal transduction in skeletal muscle. Best Practice & Research. Clinical Endocrinology & Metabolism 17 (3):385–98. doi: 10.1016/S1521-690X(03)00040-X.
   PubMed Web of Science ®Google Scholar
• Zou, Y., G. Qi, T. Xu, S. Chen, T. Liu, and Y. Huang. 2016. Optimal extraction parameters of theabrownin from Sichuan dark tea. African Journal of Traditional, Complementary and Alternative Medicines 13 (3):191–6. doi: 10.4314/ajtcam.v13i3.22.
   PubMedGoogle Scholar