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Volume 18, Issue 4

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 4 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 4 (2009)

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Reviews

Article

Aurora kinase inhibitors in preclinical and clinical testing

Chun Hei Antonio Cheung, Mohane Selvaraj Coumar, Hsing-Pang Hsieh & Jang-Yang Chang

Pages: 379-398

Published online: 01 Apr 2009

AbstractforAurora kinase inhibitors in preclinical and clinical testing | Full Text | References | PDF (911.5 KB)

527 Views
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Article

I_Kur/Kv1.5 channel blockers for the treatment of atrial fibrillation

Juan Tamargo, Ricardo Caballero, Ricardo Gómez & Eva Delpón

Pages: 399-416

Published online: 01 Apr 2009

AbstractforI_Kur/Kv1.5 channel blockers for the treatment of atrial fibrillation | Full Text | References | PDF (517 KB)

761 Views
64 CrossRef citations
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Article

Pharmacological therapy for atrial fibrillation: current options and new agents

Mohan N Viswanathan MD & Richard L Page MD FACC FAHA FHRS

Pages: 417-431

Published online: 11 Mar 2009

AbstractforPharmacological therapy for atrial fibrillation: current options and new agents | Full Text | References | PDF (407.1 KB)

106 Views
3 CrossRef citations
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Article

Targeted therapy in acute myeloid leukaemia: current status and future directions

Camilla Stapnes MD PhD, Bjørn Tore Gjertsen MD PhD, Håkon Reikvam MD & Øystein Bruserud MD PhD

Pages: 433-455

Published online: 01 Apr 2009

AbstractforTargeted therapy in acute myeloid leukaemia: current status and future directions | Full Text | References | PDF (615.9 KB)

239 Views
31 CrossRef citations
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Article

Treatment of gastrointestinal stromal tumours: imatinib, sunitinib – and then?

Bengt Nilsson, Ola Nilsson & Håkan Ahlman

Pages: 457-468

Published online: 01 Apr 2009

AbstractforTreatment of gastrointestinal stromal tumours: imatinib, sunitinib – and then? | Full Text | References | PDF (391.7 KB)

200 Views
22 CrossRef citations
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Article

Flavonoids, phenoxodiol, and a novel agent, triphendiol, for the treatment of pancreaticobiliary cancers

M Wasif Saif, Ewan Tytler, Frederick Lansigan, David M Brown & Alan J Husband

Pages: 469-479

Published online: 11 Mar 2009

AbstractforFlavonoids, phenoxodiol, and a novel agent, triphendiol, for the treatment of pancreaticobiliary cancers | Full Text | References | PDF (598.6 KB)

207 Views
27 CrossRef citations
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Article

CXCR4 chemokine receptor antagonists: perspectives in SCLC

Jan A Burger MD PhD & David J Stewart

Pages: 481-490

Published online: 01 Apr 2009

AbstractforCXCR4 chemokine receptor antagonists: perspectives in SCLC | Full Text | References | PDF (330.1 KB)

552 Views
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Drug Evaluations

Article

Ofatumumab, a second-generation anti-CD20 monoclonal antibody, for the treatment of lymphoproliferative and autoimmune disorders

Jorge Castillo MD, Cannon Milani MD & Daniel Mendez-Allwood MD

Pages: 491-500

Published online: 01 Apr 2009

AbstractforOfatumumab, a second-generation anti-CD20 monoclonal antibody, for the treatment of lymphoproliferative and autoimmune disorders | Full Text | References | PDF (322.1 KB)

486 Views
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Article

Belinostat: a new broad acting antineoplastic histone deacetylase inhibitor

Peter Gimsing MD DMSci

Pages: 501-508

Published online: 01 Apr 2009

AbstractforBelinostat: a new broad acting antineoplastic histone deacetylase inhibitor | Full Text | References | PDF (329.6 KB)

256 Views
35 CrossRef citations
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Article

DCVax^®-Brain and DC vaccines in the treatment of GBM

Christopher J Wheeler & Keith L Black

Pages: 509-519

Published online: 01 Apr 2009

AbstractforDCVax^®-Brain and DC vaccines in the treatment of GBM | Full Text | References | PDF (347.8 KB)

701 Views
45 CrossRef citations
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Article

The role of telavancin in the treatment of MRSA infections in hospital

Matteo Bassetti MD PhD, Malgorzata Mikulska, Elda Righi, Laura Nicolini & Claudio Viscoli

Pages: 521-529

Published online: 01 Apr 2009

AbstractforThe role of telavancin in the treatment of MRSA infections in hospital | Full Text | References | PDF (364.7 KB)

132 Views
11 CrossRef citations
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Article

Succinobucol: review of the metabolic, antiplatelet and cardiovascular effects

Kendrea M Muldrew PharmD BCPS & Amy M Franks PharmD

Pages: 531-539

Published online: 01 Apr 2009

AbstractforSuccinobucol: review of the metabolic, antiplatelet and cardiovascular effects | Full Text | References | PDF (358.3 KB)

226 Views
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Article

Copper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm

Gazala Khan & Sofia Merajver

Pages: 541-548

Published online: 01 Apr 2009

AbstractforCopper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm | Full Text | References | PDF (317.1 KB)

539 Views
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Meeting Highlights

Article

Antiretroviral drugs in development. A report from HIV DART 2008: frontiers in drug development for antiretroviral therapies

9 – 12 December 2008, Rio Grande, Puerto Rico

Zelalem Temesgen MD AAHIVS

Pages: 549-553

Published online: 01 Apr 2009

AbstractforAntiretroviral drugs in development. A report from HIV DART 2008: frontiers in drug development for antiretroviral therapies | Full Text | References | PDF (279.3 KB)

48 Views
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