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Volume 28, Issue 11

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 28, Issue 11 (2019)

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Expert Opinion on Investigational Drugs, Volume 28, Issue 11 (2019)

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Drug Evaluation

Article

Tezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma

Giancarlo Marone, Giuseppe Spadaro, Mariantonia Braile, Remo Poto, Gjada Criscuolo, Hadas Pahima, Stefania Loffredo, Francesca Levi-Schaffer & Gilda Varricchi

Pages: 931-940

Published online: 10 Oct 2019

AbstractforTezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma | Full Text | References | PDF (1 MB) | EPUB

1842 Views
61 CrossRef citations
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Review

Hepatocellular carcinoma: an update on investigational drugs in phase I and II clinical trials

Anne Noonan & Timothy M. Pawlik

Pages: 941-949

Published online: 12 Oct 2019

AbstractforHepatocellular carcinoma: an update on investigational drugs in phase I and II clinical trials | Full Text | References | PDF (718.8 KB) | EPUB

531 Views
24 CrossRef citations
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Review

Clinical drug development for dementia with Lewy bodies: past and present

Garam Lee, Jeffrey Cummings, Boris Decourt, James B. Leverenz & Marwan N. Sabbagh

Pages: 951-965

Published online: 28 Oct 2019

AbstractforClinical drug development for dementia with Lewy bodies: past and present | Full Text | References | PDF (1.2 MB) | EPUB

6295 Views
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Open Access

Article

Investigational BACE inhibitors for the treatment of Alzheimer’s disease

Bruno P. Imbimbo & Mark Watling

Pages: 967-975

Published online: 29 Oct 2019

AbstractforInvestigational BACE inhibitors for the treatment of Alzheimer’s disease | Full Text | References | PDF (878.9 KB) | EPUB

985 Views
84 CrossRef citations
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Review

Targeting AKT for cancer therapy

Maryam Shariati & Funda Meric-Bernstam

Pages: 977-988

Published online: 12 Oct 2019

AbstractforTargeting AKT for cancer therapy | Full Text | References | PDF (1.4 MB) | EPUB

1866 Views
123 CrossRef citations
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Review

Cyclin-dependent kinase (CDK) 9 and 4/6 inhibitors in acute myeloid leukemia (AML): a promising therapeutic approach

Daniel J. Lee & Joshua F. Zeidner

Pages: 989-1001

Published online: 22 Oct 2019

AbstractforCyclin-dependent kinase (CDK) 9 and 4/6 inhibitors in acute myeloid leukemia (AML): a promising therapeutic approach | Full Text | References | PDF (1.2 MB) | EPUB

1150 Views
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Review

Novel investigational therapeutics for generalized anxiety disorder (GAD)

Bella Schanzer, Ana Maria Rivas-Grajales, Aamir Khan & Sanjay J Mathew

Pages: 1003-1012

Published online: 28 Oct 2019

AbstractforNovel investigational therapeutics for generalized anxiety disorder (GAD) | Full Text | References | PDF (877.1 KB) | EPUB

539 Views
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Review

Recent innovations with drugs in clinical trials for neurotrophic keratitis and refractory corneal ulcers

Dominique Bremond-Gignac, Alejandra Daruich, Matthieu P Robert & Frederic Chiambaretta

Pages: 1013-1020

Published online: 15 Oct 2019

AbstractforRecent innovations with drugs in clinical trials for neurotrophic keratitis and refractory corneal ulcers | Full Text | References | PDF (774.6 KB) | EPUB

497 Views
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