Acta Oncologica, Volume 60, Issue 2 (2021)

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Acta Oncologica, Volume 60, Issue 2 (2021)

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Editorial

Editorial
Approval of new drugs in oncology – a changing pattern
Hans Hagberg
Pages: 141-142
Published online: 08 Feb 2021
CitationforApproval of new drugs in oncology – a changing pattern | Full Text | References | PDF (234.9 KB) | EPUB
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Clinical Oncology: Original Articles

Article
Efficacy evaluation of anticancer agents in single-arm clinical trials: analysis of review reports from Pharmaceuticals and Medical Devices Agency
Ken Hatogai, Yuka Kato & Chikara Hirase
Pages: 143-148
Published online: 18 Jan 2021
AbstractforEfficacy evaluation of anticancer agents in single-arm clinical trials: analysis of review reports from Pharmaceuticals and Medical Devices Agency | Full Text | References | PDF (1 MB) | EPUB
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Article
Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer – predictors of response and impact of previous radiotherapy
Åsa Kristina Öjlert, Daniel Nebdal, Marius Lund-Iversen, Renée Åstrøm Ellefsen, Odd Terje Brustugun, Jon Michael Gran, Ann Rita Halvorsen & Åslaug Helland
Pages: 149-156
Published online: 24 Dec 2020
AbstractforImmune checkpoint blockade in the treatment of advanced non-small cell lung cancer – predictors of response and impact of previous radiotherapy | Full Text | References | PDF (990.1 KB) | EPUB | Supplemental
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Article
Metronomic treatment of vinorelbine with oral capecitabine is tolerable in the randomized Phase 2 study XeNa including patients with HER2 non-amplified metastatic breast cancer
Anne Sofie Brems-Eskildsen, Søren Linnet, Hella Danø, Adam Luczak, Peter Michael Vestlev, Erik Hugger Jakobsen, Jeppe Neimann, Charlotte Buch Jensen, Trine Dongsgaard & Sven Tyge Langkjer
Pages: 157-164
Published online: 01 Dec 2020
AbstractforMetronomic treatment of vinorelbine with oral capecitabine is tolerable in the randomized Phase 2 study XeNa including patients with HER2 non-amplified metastatic breast cancer | Full Text | References | PDF (809.6 KB) | EPUB
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Article
Different expression of BRAFV600E, ALK and PD-L1 in melanoma in children and adolescents: a nationwide retrospective study in Finland in 1990–2014
Emma K. Rousi, Ilkka O. Koskivuo, Susanna M. Juteau, Lauri A. I. Talve, Micaela M. Hernberg, Pia P. Vihinen & Veli-Matti Kähäri
Pages: 165-172
Published online: 20 Aug 2020
AbstractforDifferent expression of BRAFV600E, ALK and PD-L1 in melanoma in children and adolescents: a nationwide retrospective study in Finland in 1990–2014 | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Article
The impact of comorbidities on survival in oral cancer patients: a population-based, case-control study
Mustafa Ghanizada, Kathrine Kronberg Jakobsen, Jakob Schmidt Jensen, Irene Wessel, Jesper Filtenborg Tvedskov, Christian Grønhøj & Christian von Buchwald
Pages: 173-179
Published online: 24 Oct 2020
AbstractforThe impact of comorbidities on survival in oral cancer patients: a population-based, case-control study | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Prognostic value of metastatic pattern in colorectal cancer: a multicenter retrospective analysis in a real-life cohort
H. Rumpold, P. Kirchweger, D. Niedersüß-Beke, D. Falch, H. Wundsam, S. Metz-Gercek, G. Piringer & J. Thaler
Pages: 180-186
Published online: 23 Oct 2020
AbstractforPrognostic value of metastatic pattern in colorectal cancer: a multicenter retrospective analysis in a real-life cohort | Full Text | References | PDF (912.1 KB) | EPUB | Supplemental
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Clinical Oncology: Letters to the Editor

Letter
Clinical impact of BRCA2 mRNA expression in high-grade serous ovarian cancer: validation using the TCGA cohort
Irina Tsibulak, Verena Wieser, Hannah Welponer, Katharina Leitner, Hubert Hackl, Christian Marth, Heidelinde Fiegl & Alain G. Zeimet
Pages: 187-190
Published online: 04 Nov 2020
First Page PreviewforClinical impact of BRCA2 mRNA expression in high-grade serous ovarian cancer: validation using the TCGA cohort | Full Text | References | PDF (643.1 KB) | EPUB
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Letter
Transparency in reporting of phase 3 cancer clinical trial results
Roshal R. Patel, Vivek Verma, Clifton D. Fuller, Zachary R. McCaw & Ethan B. Ludmir
Pages: 191-194
Published online: 13 Dec 2020
First Page PreviewforTransparency in reporting of phase 3 cancer clinical trial results | Full Text | References | PDF (715.8 KB) | EPUB | Supplemental
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Letter
Hepatotoxicity associated with ribociclib among breast cancer patients
Stefania Finnsdottir, Asgerdur Sverrisdottir & Einar S. Björnsson
Pages: 195-198
Published online: 04 Dec 2020
First Page PreviewforHepatotoxicity associated with ribociclib among breast cancer patients | Full Text | References | PDF (440.5 KB) | EPUB
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Radiotherapy: Original Articles

Article
Robust treatment planning of dose painting for prostate cancer based on ADC-to-Gleason score mappings – what is the potential to increase the tumor control probability?
Eric Grönlund, Erik Almhagen, Silvia Johansson, Erik Traneus, Tufve Nyholm, Camilla Thellenberg & Anders Ahnesjö
Pages: 199-206
Published online: 17 Sep 2020
AbstractforRobust treatment planning of dose painting for prostate cancer based on ADC-to-Gleason score mappings – what is the potential to increase the tumor control probability? | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Hypofractionated stereotactic photon radiotherapy of choroidal melanoma: 20-year experience
Katharina Eibenberger, Roman Dunavoelgyi, Andreas Gleiss, Aleksandra Sedova, Dietmar Georg, Richard Poetter, Karin Dieckmann & Martin Zehetmayer
Pages: 207-214
Published online: 24 Sep 2020
AbstractforHypofractionated stereotactic photon radiotherapy of choroidal melanoma: 20-year experience | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
Daily dosimetric variation between image-guided volumetric modulated arc radiotherapy and MR-guided daily adaptive radiotherapy for prostate cancer stereotactic body radiotherapy
Luca Nicosia, Gianluisa Sicignano, Michele Rigo, Vanessa Figlia, Francesco Cuccia, Antonio De Simone, Niccolò Giaj-Levra, Rosario Mazzola, Stefania Naccarato, Francesco Ricchetti, Claudio Vitale, Ruggero Ruggieri & Filippo Alongi
Pages: 215-221
Published online: 18 Sep 2020
AbstractforDaily dosimetric variation between image-guided volumetric modulated arc radiotherapy and MR-guided daily adaptive radiotherapy for prostate cancer stereotactic body radiotherapy | Full Text | References | PDF (1 MB) | EPUB
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Article
Effect of breathing motion on robustness of proton therapy plans for left-sided breast cancer patients with indication for locoregional irradiation
L. Klaassen, A. L. Petoukhova, S. J. M. Habraken, J. Jacobs, M. G. A. Sattler, K. Verhoeven & Y. L. B. Klaver
Pages: 222-228
Published online: 03 Dec 2020
AbstractforEffect of breathing motion on robustness of proton therapy plans for left-sided breast cancer patients with indication for locoregional irradiation | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article
Reduction of inter-observer contouring variability in daily clinical practice through a retrospective, evidence-based intervention
H. M. Patrick, L. Souhami & J. Kildea
Pages: 229-236
Published online: 29 Sep 2020
AbstractforReduction of inter-observer contouring variability in daily clinical practice through a retrospective, evidence-based intervention | Full Text | References | PDF (1.9 MB) | EPUB
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Article
Clinical iterative model development improves knowledge-based plan quality for high-risk prostate cancer with four integrated dose levels
Johanna Austrheim Hundvin, Kristine Fjellanger, Helge Egil Seime Pettersen, Britt Nygaard, Kari Revheim, Turid Husevåg Sulen, Christian Ekanger & Liv Bolstad Hysing
Pages: 237-244
Published online: 08 Oct 2020
AbstractforClinical iterative model development improves knowledge-based plan quality for high-risk prostate cancer with four integrated dose levels | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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Article
High-dose proton therapy and tomotherapy for the treatment of sacral chordoma: a retrospective monocentric study
Arnaud Beddok, Caroline Saint-Martin, Hamid Mammar, Loïc Feuvret, Sylvie Helfre, Stéphanie Bolle, Sebastien Froelich, Farid Goudjil, Sofia Zefkili, Malika Amessis, Dominique Peurien, Sophie Cornet, Rémi Dendale, Claire Alapetite & Valentin Calugaru
Pages: 245-251
Published online: 23 Oct 2020
AbstractforHigh-dose proton therapy and tomotherapy for the treatment of sacral chordoma: a retrospective monocentric study | Full Text | References | PDF (765.2 KB) | EPUB | Supplemental
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Article
Incorporation of the LETd-weighted biological dose in the evaluation of breast intensity-modulated proton therapy plans
Chunbo Liu, Dandan Zheng, Julie A. Bradley, Raymond B. Mailhot Vega, Yawei Zhang, Daniel J. Indelicato, Nancy Mendenhall & Xiaoying Liang
Pages: 252-259
Published online: 16 Oct 2020
AbstractforIncorporation of the LETd-weighted biological dose in the evaluation of breast intensity-modulated proton therapy plans | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Article
Simulated daily plan adaptation for magnetic resonance-guided liver stereotactic body radiotherapy
Edward Taylor, Jelena Lukovic, Michael Velec, Andrea Shessel, Teodor Stanescu, Laura Dawson, Daniel Létourneau & Patricia Lindsay
Pages: 260-266
Published online: 10 Nov 2020
AbstractforSimulated daily plan adaptation for magnetic resonance-guided liver stereotactic body radiotherapy | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 848 Views
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Article
Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors
Ole Marius Otterlei, Daniel J. Indelicato, Laura Toussaint, Kristian S. Ytre-Hauge, Sara Pilskog, Lars Fredrik Fjaera, Eivind Rørvik, Helge Egil S. Pettersen, Ludvig P. Muren, Yasmin Lassen-Ramshad, Marcos Di Pinto & Camilla H. Stokkevåg
Pages: 267-274
Published online: 02 Nov 2020
AbstractforVariation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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