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Volume 18, Issue 5

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 5 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 5 (2009)

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Original Research

Article

Synthesis and biological evaluation of novel hydrazide based cytotoxic agents

Fedora Grande, Roppei Yamada, Xuefei Cao, Francesca Aiello, Antonio Garofalo & Nouri Neamati

Pages: 555-568

Published online: 24 Apr 2009

AbstractforSynthesis and biological evaluation of novel hydrazide based cytotoxic agents | Full Text | References | PDF (1.4 MB)

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Perspective

Article

Donepezil (aricept) as a treatment for anorexia nervosa: a very feasible therapeutic possibility

Alberto Halabe Bucay

Pages: 569-571

Published online: 24 Apr 2009

AbstractforDonepezil (aricept) as a treatment for anorexia nervosa: a very feasible therapeutic possibility | Full Text | References | PDF (228.2 KB)

206 Views
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Reviews

Article

Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions

Sama F Sleiman, Manuela Basso, Lata Mahishi, Alan P Kozikowski, Mary E Donohoe, Brett Langley & Rajiv R Ratan

Pages: 573-584

Published online: 24 Apr 2009

AbstractforPutting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions | Full Text | References | PDF (1.2 MB)

254 Views
63 CrossRef citations
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Article

Cathepsin K inhibitors for osteoporosis and potential off-target effects

Dieter Brömme & Fabien Lecaille

Pages: 585-600

Published online: 24 Apr 2009

AbstractforCathepsin K inhibitors for osteoporosis and potential off-target effects | Full Text | References | PDF (2.2 MB)

901 Views
157 CrossRef citations
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Article

Investigational drugs for neuroendocrine tumours

Dan Granberg MD PhD

Pages: 601-608

Published online: 24 Apr 2009

AbstractforInvestigational drugs for neuroendocrine tumours | Full Text | References | PDF (306.6 KB)

80 Views
6 CrossRef citations
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Article

Recent developments in the treatment of uveitis: an update

Fiona Lyon, Richard P Gale & Susan Lightman

Pages: 609-616

Published online: 24 Apr 2009

AbstractforRecent developments in the treatment of uveitis: an update | Full Text | References | PDF (291.1 KB)

349 Views
14 CrossRef citations
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Article

Transcatheter arterial chemoembolization combined with or without Chinese herbal therapy for hepatocellular carcinoma: meta-analysis

William CS Cho PhD & Hai-yong Chen

Pages: 617-635

Published online: 24 Apr 2009

AbstractforTranscatheter arterial chemoembolization combined with or without Chinese herbal therapy for hepatocellular carcinoma: meta-analysis | Full Text | References | PDF (587.5 KB)

202 Views
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Article

VEGF inhibitors for the treatment of neovascular age-related macular degeneration

Mark Rami Barakat MD & PK Kaiser

Pages: 637-646

Published online: 24 Apr 2009

AbstractforVEGF inhibitors for the treatment of neovascular age-related macular degeneration | Full Text | References | PDF (305.6 KB)

741 Views
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Article

Pharmacological approaches to the treatment of obstructive sleep apnoea

Malcolm Kohler, Konrad E Bloch & John R Stradling

Pages: 647-656

Published online: 24 Apr 2009

AbstractforPharmacological approaches to the treatment of obstructive sleep apnoea | Full Text | References | PDF (311.2 KB)

485 Views
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Drug Evaluations

Article

Lixivaptan: a novel vasopressin receptor antagonist

Elaine Ku MD, Niloofar Nobakht & Vito M Campese MD

Pages: 657-662

Published online: 21 Apr 2009

AbstractforLixivaptan: a novel vasopressin receptor antagonist | Full Text | References | PDF (264.2 KB)

256 Views
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Article

Spinal cord injury and neural repair: focus on neuroregenerative approaches for spinal cord injury

Darryl C Baptiste PhD, Allyson Tighe MSc & Michael G Fehlings MD PhD FRCSC

Pages: 663-673

Published online: 21 Apr 2009

AbstractforSpinal cord injury and neural repair: focus on neuroregenerative approaches for spinal cord injury | Full Text | References | PDF (331.5 KB)

351 Views
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Article

The therapeutic potential of gamma-hydroxybutyric acid for alcohol dependence: balancing the risks and benefits. A focus on clinical data

Giovanni Addolorato MD, Lorenzo Leggio MD MSc, Anna Ferrulli MD, Fabio Caputo MD PhD & Antonio Gasbarrini MD

Pages: 675-686

Published online: 21 Apr 2009

AbstractforThe therapeutic potential of gamma-hydroxybutyric acid for alcohol dependence: balancing the risks and benefits. A focus on clinical data | Full Text | References | PDF (351.4 KB)

228 Views
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Article

Cancer vaccination with telomerase peptide GV1001

Jon Amund Kyte MD PhD

Pages: 687-694

Published online: 24 Apr 2009

AbstractforCancer vaccination with telomerase peptide GV1001 | Full Text | References | PDF (324.1 KB)

778 Views
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