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Cover image for Biologics: Targets and Therapy, Volume 17, 2023

Biologics: Targets and Therapy, Volume 17, Issue (2023)

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Biologics: Targets and Therapy, Volume 17, Issue (2023)

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Vol 18, 2024 Volume 17, 2023 Vol 16, 2022 Vol 15, 2021 Vol 14, 2020 Vol 13, 2019 Vol 12, 2018 Vol 11, 2017 Vol 10, 2016 Vol 9, 2015 Vol 8, 2014 Vol 7, 2013 Vol 6, 2012 Vol 5, 2011 Vol 4, 2010 Vol 3, 2009 Vol 2, 2008 Vol 1, 2007

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ORIGINAL RESEARCH

Article

Significance of Interleukin 23 in Systemic Lupus Patients: Relation to Disease Activity and Damage Indices

Maysa M Haroon, Gehan A Hegazy, Mohammed A Hassanien, Olfat Shaker & Wafaa H Hussein

Pages: 1-9

Published online: 18 Jan 2023

AbstractforSignificance of Interleukin 23 in Systemic Lupus Patients: Relation to Disease Activity and Damage Indices | Full Text | References | PDF (427.1 KB) | EPUB

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RESEARCH LETTER

Letter

Preliminary Assessment of Safety and Tolerability of Avacopan During the Early Access Program for ANCA-Associated Vasculitis

Jolijn R van Leeuwen, Tamara Popov, Achim Obergfell, Ton J Rabelink & YK Onno Teng

Pages: 11-14

Published online: 25 Jan 2023

First Page PreviewforPreliminary Assessment of Safety and Tolerability of Avacopan During the Early Access Program for ANCA-Associated Vasculitis | Full Text | References | PDF (320.6 KB) | EPUB

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Open Access

ORIGINAL RESEARCH

Article

The Cancer Driver Genes IDH1 and IDH2 and CD204 in WHO-Grade 4 Astrocytoma: Crosstalk Between Cancer Metabolism and Tumour Associated Macrophage Recruitment in Tumour Microenvironment

Maher Kurdi, Nasser Mulla, Yousef Katib, Taghreed Alsinani, Sahar Hakamy, Bassam MJ Addas, Husam Malibary, Taher F Halawa, Marwa S Farhan, Eyad Faizo & Saleh Baeesa

Pages: 15-22

Published online: 05 Feb 2023

AbstractforThe Cancer Driver Genes IDH1 and IDH2 and CD204 in WHO-Grade 4 Astrocytoma: Crosstalk Between Cancer Metabolism and Tumour Associated Macrophage Recruitment in Tumour Microenvironment | Full Text | References | PDF (2.4 MB) | EPUB

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Open Access

Article

Elevated Serum Vinculin in Patients with HBV/HCV-Associated Liver Cirrhosis and Hepatocellular Carcinoma: A Pilot Study

Abdallah Essa, Enas Said Essa, Sara Mahmoud El-deeb, Hossam Eldin Mostafa Seleem, Muthana Al Sahlawi, Omar Ahmed Al-Omair & Somaia Shehab-Eldeen

Pages: 23-32

Published online: 19 Mar 2023

AbstractforElevated Serum Vinculin in Patients with HBV/HCV-Associated Liver Cirrhosis and Hepatocellular Carcinoma: A Pilot Study | Full Text | References | PDF (985.4 KB) | EPUB

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Open Access

Article

Demonstration of Safety in Wild Type Mice of npFOXF1, a Novel Nanoparticle-Based Gene Therapy for Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins

Fatemeh Kohram, Zicheng Deng, Yufang Zhang, Abid Al Reza, Enhong Li, Olena A Kolesnichenko, Samriddhi Shukla, Vladimir Ustiyan, Jose Gomez-Arroyo, Anusha Acharya, Donglu Shi, Vladimir V Kalinichenko & Alan P Kenny

Pages: 43-55

Published online: 20 Mar 2023

AbstractforDemonstration of Safety in Wild Type Mice of npFOXF1, a Novel Nanoparticle-Based Gene Therapy for Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins | Full Text | References | PDF (8.4 MB) | EPUB

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LETTER

Critical Response: “Does the Mutation of Cancer Driver Genes IDH1/2 and CD204 Influence Cancer Metabolism and Tumor Associated Macrophage Recruitment in Tumor Microenvironment” [Letter]

Novaria Sari Dewi Panjaitan, Sarwo Handayani & Rita Marleta Dewi

Pages: 41-42

Published online: 20 Mar 2023

CitationforCritical Response: “Does the Mutation of Cancer Driver Genes IDH1/2 and CD204 Influence Cancer Metabolism and Tumor Associated Macrophage Recruitment in Tumor Microenvironment” [Letter] | Full Text | References | PDF (282.8 KB) | EPUB

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Open Access

REVIEW

Review

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Sintayehu Mekonnen & Hawi Farris

Pages: 33-40

Published online: 20 Mar 2023

AbstractforWhy and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article | Full Text | References | PDF (398.7 KB) | EPUB

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Open Access

CASE REPORT

Case Report

Hypereosinophilic Dermatitis: Successful Treatment with Dupilumab

Chenyu Wu, Jianzhong Zhang & Yan Zhao

Pages: 57-60

Published online: 20 Apr 2023

AbstractforHypereosinophilic Dermatitis: Successful Treatment with Dupilumab | Full Text | References | PDF (761.2 KB) | EPUB

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Open Access

CASE SERIES

Case Report

Treating Alpelisib-Induced Hyperinsulinemia in Patients with Advanced Breast Cancer – A Real-Life Experience

Ruth Percik, Cecilie Oedegaard Smith, Anca Leibovici & Ayelet Shai

Pages: 61-67

Published online: 03 May 2023

AbstractforTreating Alpelisib-Induced Hyperinsulinemia in Patients with Advanced Breast Cancer – A Real-Life Experience | Full Text | References | PDF (2.7 MB) | EPUB

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Open Access

ORIGINAL RESEARCH

Article

New Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells

Angelika Długosz-Pokorska, Renata Perlikowska, Tomasz Janecki & Anna Janecka

Pages: 69-83

Published online: 15 May 2023

AbstractforNew Uracil Analog with Exocyclic Methylidene Group Can Reverse Resistance to Taxol in MCF-7 Cancer Cells | Full Text | References | PDF (7.2 MB) | EPUB

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Open Access

REVIEW

Review

Effectiveness of RCTs Pooling Evidence on Mesenchymal Stem Cell (MSC) Therapeutic Applications During COVID-19 Epidemic: A Systematic Review

Usha Rani Kandula & Addisu Dabi Wake

Pages: 85-112

Published online: 18 May 2023

AbstractforEffectiveness of RCTs Pooling Evidence on Mesenchymal Stem Cell (MSC) Therapeutic Applications During COVID-19 Epidemic: A Systematic Review | Full Text | References | PDF (2.2 MB) | EPUB

341 Views
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Open Access

Review

Molecular Biology Mechanisms and Emerging Therapeutics of Triple-Negative Breast Cancer

Zhiying Zhang, Rui Zhang & Donghai Li

Pages: 113-128

Published online: 21 Sep 2023

AbstractforMolecular Biology Mechanisms and Emerging Therapeutics of Triple-Negative Breast Cancer | Full Text | References | PDF (2.3 MB) | EPUB

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Open Access

ORIGINAL RESEARCH

Article

Treatment Persistence of Apremilast Among Patients with Psoriatic Arthritis

Amir Haddad, Nili Stein, Idit Lavi, Lisa Shynkar, Irina Bergman, Ilan Feldhamer, Arnon Dov Cohen, Walid Saliba & Devy Zisman

Pages: 129-136

Published online: 04 Oct 2023

AbstractforTreatment Persistence of Apremilast Among Patients with Psoriatic Arthritis | Full Text | References | PDF (1.7 MB) | EPUB

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Open Access

Article

Serum LINC00152 and UCA1 in HCV-Induced Hepatocellular Carcinoma: Clinical Significance and Prognostic Value

Somaia Shehab-Eldeen, Abdallah Essa, Eman Salah Arafat, Asmaa Shaaban Sleem, Amal Abdelrasoul Alhosary, Ehab Darwish, Ali Essa, Omar Ahmed Al-Omair, Emad Ali Al-Khoufi, Abdulrhman Khaled Al Abdulqader & Ali Nada

Pages: 137-149

Published online: 13 Oct 2023

AbstractforSerum LINC00152 and UCA1 in HCV-Induced Hepatocellular Carcinoma: Clinical Significance and Prognostic Value | Full Text | References | PDF (2.2 MB) | EPUB

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Open Access

Article

Tocilizumab Vs Methotrexate in a Cohort of Patients Affected by Active GCA: A Comparative Clinical and Ultrasonographic Study

Silvia Grazzini, Edoardo Conticini, Paolo Falsetti, Miriana D’Alessandro, Jurgen Sota, Riccardo Terribili, Caterina Baldi, Claudia Fabiani, Elena Bargagli, Luca Cantarini & Bruno Frediani

Pages: 151-160

Published online: 01 Dec 2023

AbstractforTocilizumab Vs Methotrexate in a Cohort of Patients Affected by Active GCA: A Comparative Clinical and Ultrasonographic Study | Full Text | References | PDF (3.1 MB) | EPUB

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Open Access

Article

The Effect of Two Years of Secukinumab Treatment on Bone Metabolism in Patients with Radiographic Axial Spondyloarthritis: Results from Daily Clinical Practice

Mark Siderius, Stan C Kieskamp, Freke Wink, Frans GM Kroese, Suzanne Arends & Anneke Spoorenberg

Pages: 161-166

Published online: 13 Dec 2023

AbstractforThe Effect of Two Years of Secukinumab Treatment on Bone Metabolism in Patients with Radiographic Axial Spondyloarthritis: Results from Daily Clinical Practice | Full Text | References | PDF (850.7 KB) | EPUB

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Open Access

Article

Hypoxia Inducible Factor-1α Through ROS/NLRP3 Pathway Regulates the Mechanism of Acute Ischemic Stroke Microglia Scorching Mechanism

Xin Ma, Junxia Jiao, Mayila Aierken, Hong Sun & Li Chen

Pages: 167-180

Published online: 18 Dec 2023

AbstractforHypoxia Inducible Factor-1α Through ROS/NLRP3 Pathway Regulates the Mechanism of Acute Ischemic Stroke Microglia Scorching Mechanism | Full Text | References | PDF (7.1 MB) | EPUB

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