Pharmaceutical Biology, Volume 61, Issue 1 (2023)

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Pharmaceutical Biology, Volume 61, Issue 1 (2023)

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Research Article

Article
The effective constituent puerarin, from Pueraria lobata, inhibits the proliferation and inflammation of vascular smooth muscle in atherosclerosis through the miR-29b-3p/IGF1 pathway
Jianpeng Li, Yanan Li, Xiangke Yuan, Dengfeng Yao, Zongyue Gao, Zhaoyang Niu, Zheng Wang & Yue Zhang
Pages: 1-11
Published online: 20 Dec 2022
AbstractforThe effective constituent puerarin, from Pueraria lobata, inhibits the proliferation and inflammation of vascular smooth muscle in atherosclerosis through the miR-29b-3p/IGF1 pathway | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Effects of puerarin on the intervertebral disc degeneration and biological characteristics of nucleus pulposus cells
Hengtao Tang, Song Zhang, Xinchang Lu & Tongyu Geng
Pages: 12-22
Published online: 16 Dec 2022
AbstractforEffects of puerarin on the intervertebral disc degeneration and biological characteristics of nucleus pulposus cells | Full Text | References | PDF (3.3 MB) | EPUB
  • 2381 Views
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Open Access
Article
Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway
Pinglan Lin, Furong Qiu, Ming Wu, Lin Xu, Di Huang, Chen Wang, Xuejun Yang & Chaoyang Ye
Pages: 23-29
Published online: 16 Dec 2022
AbstractforSalvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway | Full Text | References | PDF (2.4 MB) | EPUB
  • 3281 Views
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Open Access
Article
Biological activities of Viscum tuberculatum aqueous leaf extract
Abraham Yirgu, Yalemtsehay Mekonnen, Amelework Eyado, Alessia Staropoli & Francesco Vinale
Pages: 30-36
Published online: 20 Dec 2022
AbstractforBiological activities of Viscum tuberculatum aqueous leaf extract | Full Text | References | PDF (1.5 MB) | EPUB
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Open Access
Article
Amelioration effects of the soybean lecithin–gallic acid complex on iron-overload-induced oxidative stress and liver damage in C57BL/6J mice
Caihong Wu, Wenxin Zhang, Feifei Yan, Wenwen Dai, Fang Fang, Yanli Gao & Weiwei Cui
Pages: 37-49
Published online: 27 Dec 2022
AbstractforAmelioration effects of the soybean lecithin–gallic acid complex on iron-overload-induced oxidative stress and liver damage in C57BL/6J mice | Full Text | References | PDF (4.2 MB) | EPUB
  • 2507 Views
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Open Access
Article
Gastric protective effect of Alpinia officinarum flavonoids: mediating TLR4/NF-κB and TRPV1 signalling pathways and gastric mucosal healing
Kaiwen Lin, Tang Deng, Huijuan Qu, Hongya Ou, Qifeng Huang, Bingmiao Gao, Xiaoliang Li & Na Wei
Pages: 50-60
Published online: 21 Dec 2022
AbstractforGastric protective effect of Alpinia officinarum flavonoids: mediating TLR4/NF-κB and TRPV1 signalling pathways and gastric mucosal healing | Full Text | References | PDF (3.6 MB) | EPUB
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Article
Andrographolide contributes to the attenuation of cardiac hypertrophy by suppressing endoplasmic reticulum stress
Qingxin Tian, Jianlong Liu, Qin Chen & Mingxiao Zhang
Pages: 61-68
Published online: 22 Dec 2022
AbstractforAndrographolide contributes to the attenuation of cardiac hypertrophy by suppressing endoplasmic reticulum stress | Full Text | References | PDF (2.3 MB) | EPUB
  • 2363 Views
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Article
Network pharmacology approach and experimental verification of Dan-Shen Decoction in the treatment of ischemic heart disease
Difei Gong, Tianyi Yuan, Ranran Wang, Shuchan Sun, Awaguli Dawuti, Shoubao Wang, Guanhua Du & Lianhua Fang
Pages: 69-79
Published online: 22 Dec 2022
AbstractforNetwork pharmacology approach and experimental verification of Dan-Shen Decoction in the treatment of ischemic heart disease | Full Text | References | PDF (3 MB) | EPUB
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Article
Protective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis
Jie Zhou, Ming Li, Zhichao Yu, Changqing Li, Lingling Zhou & Xueping Zhou
Pages: 80-88
Published online: 21 Dec 2022
AbstractforProtective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis | Full Text | References | PDF (2.4 MB) | EPUB
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Article
Prevention of seminal vesicle damage by Mucuna pruriens var. pruriens seed extract in chronic unpredictable mild stress mice
Sitthichai Iamsaard, Somboon Kietinun, Jintana Sattayasai, Kingkan Bunluepuech, Alexander Tsang-Hsien Wu & Pannawat Choowong-In
Pages: 89-99
Published online: 23 Dec 2022
AbstractforPrevention of seminal vesicle damage by Mucuna pruriens var. pruriens seed extract in chronic unpredictable mild stress mice | Full Text | References | PDF (3.7 MB) | EPUB
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Article
Investigation of the mechanism of tanshinone IIA to improve cognitive function via synaptic plasticity in epileptic rats
Chen Jia, Rui Zhang, Liming Wei, Jiao Xie, Suqin Zhou, Wen Yin, Xi Hua, Nan Xiao, Meile Ma & Haisheng Jiao
Pages: 100-110
Published online: 22 Dec 2022
AbstractforInvestigation of the mechanism of tanshinone IIA to improve cognitive function via synaptic plasticity in epileptic rats | Full Text | References | PDF (2.5 MB) | EPUB
  • 1958 Views
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Article
Zhizhu decoction alleviates slow transit constipation by regulating aryl hydrocarbon receptor through gut microbiota
Yong Wen, Yu Zhan, Shiyu Tang, Fang Liu, Rong Wu, Pengfei Kong, Qian Li & Xuegui Tang
Pages: 111-124
Published online: 23 Dec 2022
AbstractforZhizhu decoction alleviates slow transit constipation by regulating aryl hydrocarbon receptor through gut microbiota | Full Text | References | PDF (3.7 MB) | EPUB
  • 2567 Views
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Article
Therapeutic effects of Bombax ceiba flower aqueous extracts against loperamide-induced constipation in mice
Liuping Wang, Shiyuan Xie, Xuan Jiang, Caini Xu, Youqiong Wang, Jianfang Feng & Bin Yang
Pages: 125-134
Published online: 29 Dec 2022
AbstractforTherapeutic effects of Bombax ceiba flower aqueous extracts against loperamide-induced constipation in mice | Full Text | References | PDF (3.8 MB) | EPUB
  • 2233 Views
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Article
Anti-neuroinflammatory effects of alkaloid-enriched extract from Huperzia serrata on lipopolysaccharide-stimulated BV-2 microglial cells
Thu Kim Dang, Seong-Min Hong, Vui Thi Dao, Phuong Thi Thu Tran, Hiep Tuan Tran, Giang Hoang Do, Thanh Nguyen Hai, Hang Thi Nguyet Pham & Sun Yeou Kim
Pages: 135-143
Published online: 08 Jan 2023
AbstractforAnti-neuroinflammatory effects of alkaloid-enriched extract from Huperzia serrata on lipopolysaccharide-stimulated BV-2 microglial cells | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Da-Cheng-Qi decoction improves severe acute pancreatitis-associated acute lung injury by interfering with intestinal lymphatic pathway and reducing HMGB1-induced inflammatory response in rats
Xiaowen Liu, Lin Yuan, Yishuang Tang, Yue Wu, Jing Kong, Bingduo Zhou, Xiaosu Wang, Min Lin, Yading Li, Gaofan Xu, Yi Wang, Tingting Xu, Cong He, Shengquan Fang & Shengliang Zhu
Pages: 144-154
Published online: 09 Jan 2023
AbstractforDa-Cheng-Qi decoction improves severe acute pancreatitis-associated acute lung injury by interfering with intestinal lymphatic pathway and reducing HMGB1-induced inflammatory response in rats | Full Text | References | PDF (2.2 MB) | EPUB
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Open Access
Article
Screening of rosmarinic acid from Salvia miltiorrhizae acting on the novel target TRPC1 based on the ‘homology modelling–virtual screening–molecular docking–affinity assay–activity evaluation’ method
Wei Quan, Yuan Wang, Yu-han Chen, Qing Shao, Yang-ze Gong, Jie-wen Hu, Wei-hai Liu, Zi-jun Wu, Jie Wang, Shan-bo Ma & Xiao-qiang Li
Pages: 155-164
Published online: 05 Jan 2023
AbstractforScreening of rosmarinic acid from Salvia miltiorrhizae acting on the novel target TRPC1 based on the ‘homology modelling–virtual screening–molecular docking–affinity assay–activity evaluation’ method | Full Text | References | PDF (1.9 MB) | EPUB
  • 2183 Views
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Article
Luteolin alleviated neutrophilic asthma by inhibiting IL-36γ secretion-mediated MAPK pathways
Xin-rui Qiao, Tao Feng, Dong Zhang, Li-li Zhi, Jin-tao Zhang, Xiao-fei Liu, Yun Pan, Jia-wei Xu, Wen-Jing Cui & Liang Dong
Pages: 165-176
Published online: 05 Jan 2023
AbstractforLuteolin alleviated neutrophilic asthma by inhibiting IL-36γ secretion-mediated MAPK pathways | Full Text | References | PDF (3.1 MB) | EPUB
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Review Article

Review
Advances for pharmacological activities of Polygonum cuspidatum - A review
Jia Ke, Meng-Ting Li, Shuyang Xu, Jianpeng Ma, Ming-Yuan Liu & Yan Han
Pages: 177-188
Published online: 09 Jan 2023
AbstractforAdvances for pharmacological activities of Polygonum cuspidatum - A review | Full Text | References | PDF (1.6 MB) | EPUB
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Research Article

Article
Antihyperglycemic effects of Lysiphyllum strychnifolium leaf extract in vitro and in vivo
Arman Syah Goli, Vilasinee Hirunpanich Sato, Hitoshi Sato, Savita Chewchinda, Jiraporn Leanpolchareanchai, Jannarin Nontakham, Jantana Yahuafai, Thavaree Thilavech, Pongsatorn Meesawatsom & Metawee Maitree
Pages: 189-200
Published online: 10 Jan 2023
AbstractforAntihyperglycemic effects of Lysiphyllum strychnifolium leaf extract in vitro and in vivo | Full Text | References | PDF (2.1 MB) | EPUB
  • 3534 Views
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Article
Antinociceptive activity of doliroside B
Xishan Bai, Yanhong Li, Yuxiao Li, Min Li, Ming Luo, Kai Tian, Mengyuan Jiang, Yong Xiong, Ya Lu, Yukui Li, Haibo Yu & Xiangzhong Huang
Pages: 201-212
Published online: 10 Jan 2023
AbstractforAntinociceptive activity of doliroside B | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 1870 Views
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Open Access
Article
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway
Jin Ding, Baowei Lu, Lumei Liu, Zixuan Zhong, Neng Wang, Bonan Li, Wen Sheng & Qinghu He
Pages: 213-227
Published online: 23 Jan 2023
AbstractforGuilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway | Full Text | References | PDF (5.8 MB) | EPUB
  • 2405 Views
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Article
Da-Yuan-Yin decoction polyphenol fraction attenuates acute lung injury induced by lipopolysaccharide
Lengqiu Guo, Yun Yang, Jie Yuan, Huiling Ren, Xiaolei Huang, Meng Li, Long Xia, Xiaogang Jiang, Daofeng Chen & Jian Zhang
Pages: 228-240
Published online: 18 Jan 2023
AbstractforDa-Yuan-Yin decoction polyphenol fraction attenuates acute lung injury induced by lipopolysaccharide | Full Text | References | PDF (4 MB) | EPUB
  • 2132 Views
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Article
Alpha-Mangosteen lessens high-fat/high-glucose diet and low-dose streptozotocin induced-hepatic manifestations in the insulin resistance rat model
Vivian Soetikno, Prisma Andini, Miskiyah Iskandar, Clark Christensen Matheos, Joshua Alward Herdiman, Iqbal Kevin Kyle, Muhammad Nur Imaduddin Suma, Melva Louisa & Ari Estuningtyas
Pages: 241-248
Published online: 18 Jan 2023
AbstractforAlpha-Mangosteen lessens high-fat/high-glucose diet and low-dose streptozotocin induced-hepatic manifestations in the insulin resistance rat model | Full Text | References | PDF (2 MB) | EPUB
  • 2227 Views
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Article
Chaihu Shugan San promotes gastric motility in rats with functional dyspepsia by regulating Drp-1-mediated ICC mitophagy
Li Li, Qingling Jia, Xiangxiang Wang, Yujiao Wang, Chenheng Wu, Jun Cong & Jianghong Ling
Pages: 249-258
Published online: 18 Jan 2023
AbstractforChaihu Shugan San promotes gastric motility in rats with functional dyspepsia by regulating Drp-1-mediated ICC mitophagy | Full Text | References | PDF (2.9 MB) | EPUB
  • 2134 Views
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Article
Exploring the pharmacological mechanisms of Shuanghuanglian against T-cell acute lymphoblastic leukaemia through network pharmacology combined with molecular docking and experimental validation
You Yang, Yan Yang, Yunfu Shen, Jing Liu, Yan Zeng, Chengming Wei, Chunyan Liu, Yansha Pan, Qulian Guo, Fangfang Zhong, Ling Guo & Wenjun Liu
Pages: 259-270
Published online: 19 Jan 2023
AbstractforExploring the pharmacological mechanisms of Shuanghuanglian against T-cell acute lymphoblastic leukaemia through network pharmacology combined with molecular docking and experimental validation | Full Text | References | PDF (3.5 MB) | EPUB
  • 2529 Views
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Article
Qiangjing tablets ameliorate asthenozoospermia via mitochondrial ubiquitination and mitophagy mediated by LKB1/AMPK/ULK1 signaling
Guangsen Li, Yuanjie Xu, Yingxi Li, Degui Chang, Peihai Zhang, Ziyang Ma, Di’ang Chen, Yaodong You, Xiaopeng Huang & Jian Cai
Pages: 271-280
Published online: 19 Jan 2023
AbstractforQiangjing tablets ameliorate asthenozoospermia via mitochondrial ubiquitination and mitophagy mediated by LKB1/AMPK/ULK1 signaling | Full Text | References | PDF (3.2 MB) | EPUB
  • 2285 Views
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Article
Mechanisms of action of Lycium barbarum polysaccharide in protecting against vitiligo mice through modulation of the STAT3-Hsp70-CXCL9/CXCL10 pathway
Liqian Peng, Yue Lu, Yingming Gu, Bihua Liang, Yanhong Li, Huaping Li, Yanan Ke, Huilan Zhu & Zhenjie Li
Pages: 281-287
Published online: 18 Jan 2023
AbstractforMechanisms of action of Lycium barbarum polysaccharide in protecting against vitiligo mice through modulation of the STAT3-Hsp70-CXCL9/CXCL10 pathway | Full Text | References | PDF (2.5 MB) | EPUB
  • 2304 Views
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Article
Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis through restoration of Sirt3 expression
Yuan Ji-hong, Ma Yu, Yuan Ling-hong, Gong Jing-jing, Xu Ling-li, Wang Lv & Jin Yong-mei
Pages: 288-297
Published online: 23 Feb 2023
AbstractforBaicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis through restoration of Sirt3 expression | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 3336 Views
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Article
Nanocurcumin preserves kidney function and haematology parameters in DMBA-induced ovarian cancer treated with cisplatin via its antioxidative and anti-inflammatory effect in rats
Melva Louisa, Erico Wanafri, Wawaimuli Arozal, Ni Made Dwi Sandhiutami & Ahmad Muhammad Basalamah
Pages: 298-305
Published online: 28 Jan 2023
AbstractforNanocurcumin preserves kidney function and haematology parameters in DMBA-induced ovarian cancer treated with cisplatin via its antioxidative and anti-inflammatory effect in rats | Full Text | References | PDF (2.5 MB) | EPUB
  • 1977 Views
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Article
Protective effect of omega-3 polyunsaturated fatty acids on sepsis via the AMPK/mTOR pathway
Peng Liu, Ming Li, Wei Wu, Anjie Liu, Honglin Hu, Qin Liu & Chengzhi Yi
Pages: 306-315
Published online: 24 Jan 2023
AbstractforProtective effect of omega-3 polyunsaturated fatty acids on sepsis via the AMPK/mTOR pathway | Full Text | References | PDF (3.1 MB) | EPUB
  • 2142 Views
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Article
Panax ginseng improves physical recovery and energy utilization on chronic fatigue in rats through the PI3K/AKT/mTOR signalling pathway
Guolei Zhang, BoFan Lu, Enhui Wang, Wei Wang, Zheng Li, Lili Jiao, Hui Li & Wei Wu
Pages: 316-323
Published online: 25 Jan 2023
AbstractforPanax ginseng improves physical recovery and energy utilization on chronic fatigue in rats through the PI3K/AKT/mTOR signalling pathway | Full Text | References | PDF (1.5 MB) | EPUB
  • 2399 Views
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Review

Review
Efficacy and safety of Tripterygium glycosides as an add-on treatment in adults with chronic urticaria: a systematic review and meta-analysis
Ming Li, Yan Li & Lujing Xiang
Pages: 324-336
Published online: 24 Jan 2023
AbstractforEfficacy and safety of Tripterygium glycosides as an add-on treatment in adults with chronic urticaria: a systematic review and meta-analysis | Full Text | References | PDF (3.5 MB) | EPUB
  • 1861 Views
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Research Article

Article
Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells
Rui-Yi Yang, Jia-Yi Tan, Zhe Liu, Xiao-Ling Shen & Ying-Jie Hu
Pages: 337-344
Published online: 28 Jan 2023
AbstractforLappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells | Full Text | References | PDF (1.9 MB) | EPUB
  • 1830 Views
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Article
Prokinetic effects of Citrus reticulata and Citrus aurantium extract with/without Bupleurum chinense using multistress-induced delayed gastric emptying models
Yanrong Gong, Xiaoxia Liang, Yanting Dai, Xiang Huang, Qiaozhen Su, Yan Ma, Fenglian Chen & Shuling Wang
Pages: 345-355
Published online: 02 Feb 2023
AbstractforProkinetic effects of Citrus reticulata and Citrus aurantium extract with/without Bupleurum chinense using multistress-induced delayed gastric emptying models | Full Text | References | PDF (2.3 MB) | EPUB
  • 1427 Views
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Article
Assessments of CYP‑inhibition‑based drug–drug interaction between vonoprazan and poziotinib in vitro and in vivo
Shan Zhou, Fang-Ling Zhao, Shuang-Hu Wang, Yi-Ran Wang, Yun Hong, Quan Zhou, Pei-Wu Geng, Qing-Feng Luo, Jian-Ping Cai & Da-Peng Dai
Pages: 356-361
Published online: 02 Feb 2023
AbstractforAssessments of CYP‑inhibition‑based drug–drug interaction between vonoprazan and poziotinib in vitro and in vivo | Full Text | References | PDF (992.6 KB) | EPUB
  • 1661 Views
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Article
Kazinol B protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced cardiac injury by modulating the AKT/AMPK/Nrf2 signalling pathway
Qian Zhang, Yuan-Ye Dang, Xiu Luo, Ji-Jun Fu, Zhi-Cong Zou, Xue-Jing Jia, Guo-Dong Zheng & Chu-Wen Li
Pages: 362-371
Published online: 05 Feb 2023
AbstractforKazinol B protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced cardiac injury by modulating the AKT/AMPK/Nrf2 signalling pathway | Full Text | References | PDF (1.9 MB) | EPUB
  • 2196 Views
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Review article

Review
Direct and indirect targets of carboxyatractyloside, including overlooked toxicity toward nucleoside diphosphate kinase (NDPK) and mitochondrial H+ leak
Andrzej M. Woyda-Ploszczyca
Pages: 372-390
Published online: 17 Feb 2023
AbstractforDirect and indirect targets of carboxyatractyloside, including overlooked toxicity toward nucleoside diphosphate kinase (NDPK) and mitochondrial H+ leak | Full Text | References | PDF (4 MB) | EPUB
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Research Article

Article
Regulation of bone and fat balance by Fructus Ligustri Lucidi in ovariectomized mice
Xiaoyan Qin, Qiu Wei, Ran An, Yun Yang, Mingqi Cai, Xiaoling Han, Haoping Mao & Xiumei Gao
Pages: 391-403
Published online: 05 Feb 2023
AbstractforRegulation of bone and fat balance by Fructus Ligustri Lucidi in ovariectomized mice | Full Text | References | PDF (3.1 MB) | EPUB
  • 2328 Views
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Article
Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11
Jianjie Rong, Chuanyong Li, Qiang Zhang, Guangfeng Zheng, Weijian Fan, Zhichang Pan & Shuming Shi
Pages: 404-415
Published online: 06 Jul 2023
AbstractforHydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11 | Full Text | References | PDF (3.7 MB) | EPUB
  • 2077 Views
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Article
Morroniside ameliorates glucocorticoid-induced osteoporosis and promotes osteoblastogenesis by interacting with sodium-glucose cotransporter 2
Hou-Zhi Yang, Runbei Dong, Yutao Jia, Yuqiao Li, Gan Luo, Tianhao Li, Yao Long, Shuang Liang, Shanshan Li, Xin Jin & Tianwei Sun
Pages: 416-426
Published online: 14 Feb 2023
AbstractforMorroniside ameliorates glucocorticoid-induced osteoporosis and promotes osteoblastogenesis by interacting with sodium-glucose cotransporter 2 | Full Text | References | PDF (3.6 MB) | EPUB
  • 1613 Views
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Article
Sanziguben polysaccharides improve diabetic nephropathy in mice by regulating gut microbiota to inhibit the TLR4/NF-κB/NLRP3 signalling pathway
Fan Wang, Chang Liu, LingZhi Ren, YanYang Li, HongMei Yang, Yang Yu & WeiPing Xu
Pages: 427-436
Published online: 11 Feb 2023
AbstractforSanziguben polysaccharides improve diabetic nephropathy in mice by regulating gut microbiota to inhibit the TLR4/NF-κB/NLRP3 signalling pathway | Full Text | References | PDF (3.1 MB) | EPUB
  • 3808 Views
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Article
Tongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study
Jiantao Liu, Chunping Liu, Huiqi Chen, Huan Cen, Hailong Yang, Peijian Liu, Fang Liu, Liuling Ma, Quanfu Chen & Lei Wang
Pages: 437-448
Published online: 15 Feb 2023
AbstractforTongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study | Full Text | References | PDF (4.6 MB) | EPUB
  • 2799 Views
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Article
Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor
Jimei Zhang, Chonghong Zhang, Li Miao, Zimin Meng, Ning Gu & Guifang Song
Pages: 449-458
Published online: 14 Feb 2023
AbstractforStigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor | Full Text | References | PDF (3.4 MB) | EPUB
  • 1958 Views
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Article
Panax notoginseng saponins (PNS) attenuate Th17 cell differentiation in CIA mice via inhibition of nuclear PKM2-mediated STAT3 phosphorylation
Mei-Yu Shen, Yu-Xi Di, Xiang Wang, Feng-Xiang Tian, Ming-Fei Zhang, Fei-Ya Qian, Bao-Ping Jiang, Xue-Ping Zhou & Ling-Ling Zhou
Pages: 459-472
Published online: 16 Feb 2023
AbstractforPanax notoginseng saponins (PNS) attenuate Th17 cell differentiation in CIA mice via inhibition of nuclear PKM2-mediated STAT3 phosphorylation | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 2449 Views
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Article
PI3K/AKT/SERBP-1 pathway regulates Alisma orientalis beverage treatment of atherosclerosis in APOE−/− high-fat diet mice
Ruiyi Liu, Yan Sun, Dong Di, Xiyuan Zhang, Boran Zhu & Haoxin Wu
Pages: 473-487
Published online: 24 Feb 2023
AbstractforPI3K/AKT/SERBP-1 pathway regulates Alisma orientalis beverage treatment of atherosclerosis in APOE−/− high-fat diet mice | Full Text | References | PDF (3.7 MB) | EPUB
  • 2108 Views
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Article
Repair mechanism of Yishen Tongluo formula on mouse sperm DNA fragmentation caused by polystyrene microplastics
Chenming Zhang, Zulong Wang, Sicheng Ma, Rubing Chen, Shiqi Wang, Hao Zhang, Zhong Hua & Zixue Sun
Pages: 488-498
Published online: 09 Mar 2023
AbstractforRepair mechanism of Yishen Tongluo formula on mouse sperm DNA fragmentation caused by polystyrene microplastics | Full Text | References | PDF (3 MB) | EPUB
  • 2237 Views
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Article
Tongmai Yangxin pill alleviates myocardial no-reflow by activating GPER to regulate HIF-1α signaling and downstream potassium channels
Ting Chen, Yulong Zhang, Manyun Chen, Pu Yang, Yi Wang, Wei Zhang, Weihua Huang & Wei Zhang
Pages: 499-513
Published online: 09 Mar 2023
AbstractforTongmai Yangxin pill alleviates myocardial no-reflow by activating GPER to regulate HIF-1α signaling and downstream potassium channels | Full Text | References | PDF (5 MB) | EPUB
  • 1943 Views
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Article
Lack of pharmacokinetic interaction between derazantinib and naringin in rats
Ya-nan Liu, Jie Chen, Xinhao Xu, Yingying Hu, Jin-yu Hu, Ren-ai Xu & Guanyang Lin
Pages: 514-519
Published online: 08 Mar 2023
AbstractforLack of pharmacokinetic interaction between derazantinib and naringin in rats | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Prediction of the mechanisms of action of Qutan Huoxue decoction in non-alcoholic steatohepatitis (NASH): a network pharmacology study and experimental validation
Xia Wu, Yurong Zhang, Ding Zheng, Yue Yin, Mengyun Peng, Jing Wang & Xiaoning Zhu
Pages: 520-530
Published online: 12 Mar 2023
AbstractforPrediction of the mechanisms of action of Qutan Huoxue decoction in non-alcoholic steatohepatitis (NASH): a network pharmacology study and experimental validation | Full Text | References | PDF (3.9 MB) | EPUB
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Article
Effects of Tiaopi Xiezhuo decoction on constipation and gut dysbiosis in patients with peritoneal dialysis
Yu Peng, Yuting Zeng, Tingting Zheng, Xiaoning Xie, Jianfeng Wu, Lizhe Fu, Fuhua Lu, La Zhang, Yang Chen, Xusheng Liu & Lei Wang
Pages: 531-540
Published online: 30 Mar 2023
AbstractforEffects of Tiaopi Xiezhuo decoction on constipation and gut dysbiosis in patients with peritoneal dialysis | Full Text | References | PDF (2.4 MB) | EPUB
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Article
Chinese herbal compound Huangqin Qingrechubi capsule reduces lipid metabolism disorder and inflammatory response in gouty arthritis via the LncRNA H19/APN/PI3K/AKT cascade
Xianheng Zhang, Jian Liu, Yanqiu Sun, Qin Zhou, Xiang Ding & Xiaolu Chen
Pages: 541-555
Published online: 30 Mar 2023
AbstractforChinese herbal compound Huangqin Qingrechubi capsule reduces lipid metabolism disorder and inflammatory response in gouty arthritis via the LncRNA H19/APN/PI3K/AKT cascade | Full Text | References | PDF (3.9 MB) | EPUB
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Article
Isoalantolactone suppresses gallbladder cancer progression via inhibiting the ERK signalling pathway
Xingyu Lv, Yuqi Lin, Xi Zhu & Xiujun Cai
Pages: 556-567
Published online: 30 Mar 2023
AbstractforIsoalantolactone suppresses gallbladder cancer progression via inhibiting the ERK signalling pathway | Full Text | References | PDF (3.8 MB) | EPUB
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Article
Wen-Shen-Tong-Luo-Zhi-Tong Decoction regulates bone–fat balance in osteoporosis by adipocyte-derived exosomes
Lining Wang, Yalan Pan, Mengmig Liu, Jie Sun, Li Yun, Pengcheng Tu, Chengjie Wu, Ziceng Yu, Zhitao Han, Muzhe Li, Yang Guo & Yong Ma
Pages: 568-580
Published online: 31 Mar 2023
AbstractforWen-Shen-Tong-Luo-Zhi-Tong Decoction regulates bone–fat balance in osteoporosis by adipocyte-derived exosomes | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Article
Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway
Cuixia Liang, Yongjie Jiang & Lizhu Sun
Pages: 581-589
Published online: 30 Mar 2023
AbstractforVitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
Absolute oral bioavailability and possible metabolic pathway of panduratin A from Boesenbergia rotunda extract in beagle dogs
Tussapon Boonyarattanasoonthorn, Teetat Kongratanapasert, Apisada Jiso, Pinnakarn Techapichetvanich, Nitra Nuengchamnong, Kittitach Supannapan, Anusak Kijtawornrat & Phisit Khemawoot
Pages: 590-597
Published online: 30 Mar 2023
AbstractforAbsolute oral bioavailability and possible metabolic pathway of panduratin A from Boesenbergia rotunda extract in beagle dogs | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Sinisan ameliorates colonic injury induced by water immersion restraint stress by enhancing intestinal barrier function and the gut microbiota structure
Xiaoying Xu, Huimei Hu, Haizhou Zeng, Boyi Li, Qiuxiong Yin, Yupeng Jiang, Linquan Zang, Changlin Zhao & Guoqiang Qian
Pages: 598-609
Published online: 04 Apr 2023
AbstractforSinisan ameliorates colonic injury induced by water immersion restraint stress by enhancing intestinal barrier function and the gut microbiota structure | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
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Review
Efficacy and safety of Ginkgo biloba extract as an adjuvant in the treatment of Chinese patients with sudden hearing loss: a meta-analysis
Chao Yuan, Huan Zhang, Cuicui Sun & Kai Zhang
Pages: 610-620
Published online: 31 Mar 2023
AbstractforEfficacy and safety of Ginkgo biloba extract as an adjuvant in the treatment of Chinese patients with sudden hearing loss: a meta-analysis | Full Text | References | PDF (2.6 MB) | EPUB
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Article
Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy
Mingyue Ma, Na Wei, Jieren Yang, Tingting Ding, Anping Song, Lerong Chen, Shuguo Zheng & Huanhuan Jin
Pages: 621-629
Published online: 03 Apr 2023
AbstractforSchisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy | Full Text | References | PDF (2.5 MB) | EPUB
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Article
The protective effect of 999 XiaoErGanMao granules on the lungs and intestines of influenza A virus-infected mice
Yuan-zhen Hao, Li-feng Cen, Ting Wang, Tong Yi, Xun-long Shi, Hui-juan Duan, Zhi Dai, Hai-yan Zhu & Jian-guo Tang
Pages: 630-638
Published online: 10 Apr 2023
AbstractforThe protective effect of 999 XiaoErGanMao granules on the lungs and intestines of influenza A virus-infected mice | Full Text | References | PDF (2.8 MB) | EPUB
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Review

Review
Biological effects of bergamot and its potential therapeutic use as an anti-inflammatory, antioxidant, and anticancer agent
Sabrina Adorisio, Isabella Muscari, Alessandra Fierabracci, Trinh Thi Thuy, Maria Cristina Marchetti, Emira Ayroldi & Domenico Vittorio Delfino
Pages: 639-646
Published online: 17 Apr 2023
AbstractforBiological effects of bergamot and its potential therapeutic use as an anti-inflammatory, antioxidant, and anticancer agent | Full Text | References | PDF (1.4 MB) | EPUB
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Article
JianPi-QingHua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-κB pathway in high-fat-diet-fed C57BL/6 mice
Jing Tian, Mengjie Cai, Shenyi Jin, Qingguang Chen, Jiahui Xu, Qiuyue Guo, Zihui Yan, Xu Han & Hao Lu
Pages: 647-656
Published online: 11 Apr 2023
AbstractforJianPi-QingHua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-κB pathway in high-fat-diet-fed C57BL/6 mice | Full Text | References | PDF (3.1 MB) | EPUB
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Article
Promising anti-Helicobacterpylori and anti-inflammatory metabolites from unused parts of Phoenix dactylifera CV ‘Zaghloul’: in vitro and in silico study
Nada Elhefni, Sherif S. Ebada, Marwa M. Abdel-Aziz, El-Sayed M. Marwan, Saleh El-Sharkawy & Mona El-Neketi
Pages: 657-665
Published online: 24 Apr 2023
AbstractforPromising anti-Helicobacterpylori and anti-inflammatory metabolites from unused parts of Phoenix dactylifera CV ‘Zaghloul’: in vitro and in silico study | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Article
Ligustrazine inhibits inflammatory response of human endometrial stromal cells through the STAT3/IGF2BP1/RELA axis
Ying Feng, Han Dong & Liyan Zheng
Pages: 666-673
Published online: 24 Apr 2023
AbstractforLigustrazine inhibits inflammatory response of human endometrial stromal cells through the STAT3/IGF2BP1/RELA axis | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
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Article
Modified Zhibai Dihuang pill alleviated urinary tract infection induced by extended-spectrum β-lactamase Escherichia coli in rats by regulating biofilm formation
Kaifa Chen, Yongsheng Zhu, Hongwei Su, Hao Jiang & Xin Liu
Pages: 674-682
Published online: 25 Apr 2023
AbstractforModified Zhibai Dihuang pill alleviated urinary tract infection induced by extended-spectrum β-lactamase Escherichia coli in rats by regulating biofilm formation | Full Text | References | PDF (2.3 MB) | EPUB
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Article
Hawthorn leaves flavonoids attenuate cardiac remodeling induced by simulated microgravity
Tian Liu, Yuqi Ma, Hui Zhao, Pengli Wang, Yan Niu, Yuehuan Hu, Xi Shen, Mingxia Zhang, Bing Yan & Jun Yu
Pages: 683-695
Published online: 25 Apr 2023
AbstractforHawthorn leaves flavonoids attenuate cardiac remodeling induced by simulated microgravity | Full Text | References | PDF (4 MB) | EPUB
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Article
Sanguinarine inhibits melanoma invasion and migration by targeting the FAK/PI3K/AKT/mTOR signalling pathway
Xiaoyi Qi, Yonglan Chen, Sha Liu, Li Liu, Zehui Yu, Ling Yin, Lu Fu, Mingming Deng, Sicheng Liang & Muhan Lü
Pages: 696-709
Published online: 24 Apr 2023
AbstractforSanguinarine inhibits melanoma invasion and migration by targeting the FAK/PI3K/AKT/mTOR signalling pathway | Full Text | References | PDF (5.6 MB) | EPUB
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Article
Danggui Buxue decoction alleviates cyclophosphamide-induced myelosuppression by regulating β-hydroxybutyric acid metabolism and suppressing oxidative stress
Yiqiao Gao, Yixin Zhang, Wei Liu, Nan Zhang, Qinghe Gao, Jingfang Shangguan, Na Li, Ying Zhao & Yanlong Jia
Pages: 710-721
Published online: 25 Apr 2023
AbstractforDanggui Buxue decoction alleviates cyclophosphamide-induced myelosuppression by regulating β-hydroxybutyric acid metabolism and suppressing oxidative stress | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Chinese medicinal herbs for reducing endocrine therapy-induced side effects in patients with hormone receptor‐positive breast cancer: a systematic review and meta-analysis
Shaoqing Chen, Yifang Gao, Haichao Liu, Jin Jing, Zhengyu Yang, Haoming Zhu, Bairui Chen, Yu Wang, Ting Zhang, Shizhong Wang & Jianping Lin
Pages: 722-736
Published online: 25 Apr 2023
AbstractforChinese medicinal herbs for reducing endocrine therapy-induced side effects in patients with hormone receptor‐positive breast cancer: a systematic review and meta-analysis | Full Text | References | PDF (4.2 MB) | EPUB
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Article
Hepatoprotective effect of protocatechuic acid against type 2 diabetes-induced liver injury
Kaixia Xu, Guang Lu, Qianjin Feng, Shuangchao Chen & Yonghui Wang
Pages: 737-745
Published online: 02 May 2023
AbstractforHepatoprotective effect of protocatechuic acid against type 2 diabetes-induced liver injury | Full Text | References | PDF (1.9 MB) | EPUB
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Article
Daphnetin alleviates neuropathic pain in chronic constrictive injury rats via regulating the NF-κB dependent CXCL1/CXCR2 signaling pathway
Tianrui Zhang, Wulin Liang, Wenjing Ou, Mingqian Zhang, Shuang Cui & Shuofeng Zhang
Pages: 746-754
Published online: 13 May 2023
AbstractforDaphnetin alleviates neuropathic pain in chronic constrictive injury rats via regulating the NF-κB dependent CXCL1/CXCR2 signaling pathway | Full Text | References | PDF (3.2 MB) | EPUB
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Article
Protective effects of vitamin D3 (cholecalciferol) on vancomycin-induced oxidative nephrotoxic damage in rats
Rouba Yasser Al-Sroji, Shaza Al-Laham & Ahmad Almandili
Pages: 755-766
Published online: 04 May 2023
AbstractforProtective effects of vitamin D3 (cholecalciferol) on vancomycin-induced oxidative nephrotoxic damage in rats | Full Text | References | PDF (2.7 MB) | EPUB
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Correction

Correction
Correction
Page: 767
Published online: 08 May 2023
CitationforCorrection | Full Text | PDF (145 KB) | EPUB
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Research Article

Article
Angelica sinensis polysaccharides alleviate the oxidative burden on hematopoietic cells by restoring 5-fluorouracil-induced oxidative damage in perivascular mesenchymal progenitor cells
Yilin Niu, Hanxianzhi Xiao, Biyao Wang, Ziling Wang, Kunhang Du, Yaping Wang & Lu Wang
Pages: 768-778
Published online: 06 May 2023
AbstractforAngelica sinensis polysaccharides alleviate the oxidative burden on hematopoietic cells by restoring 5-fluorouracil-induced oxidative damage in perivascular mesenchymal progenitor cells | Full Text | References | PDF (2.6 MB) | EPUB
  • 2324 Views
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Article
Gualou Guizhi decoction promotes therapeutic angiogenesis via the miR210/HIF/VEGF pathway in vivo and in vitro
Yuqin Zhang, Yajun Cao, Yan Li, Lijuan Xiao, Wei Xu, Wen Xu, Mei Huang, Xiaoqin Zhang, Yaping Chen & Lihong Nan
Pages: 779-789
Published online: 09 May 2023
AbstractforGualou Guizhi decoction promotes therapeutic angiogenesis via the miR210/HIF/VEGF pathway in vivo and in vitro | Full Text | References | PDF (2.8 MB) | EPUB
  • 2157 Views
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Article
Acacetin-loaded microemulsion for transdermal delivery: preparation, optimization and evaluation
Yajing Wang, Qian Chen, Xianfeng Huang & Xiaojing Yan
Pages: 790-798
Published online: 10 May 2023
AbstractforAcacetin-loaded microemulsion for transdermal delivery: preparation, optimization and evaluation | Full Text | References | PDF (1.8 MB) | EPUB
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Review

Review
The traditional herb Polygonum hydropiper from China: a comprehensive review on phytochemistry, pharmacological activities and applications
Yi-Dan Kong, Ying Qi, Na Cui, Zhi-Hong Zhang, Na Wei, Chang-Fu Wang, Yuan-Ning Zeng, Yan-Ping Sun, Hai-Xue Kuang & Qiu-Hong Wang
Pages: 799-814
Published online: 17 May 2023
AbstractforThe traditional herb Polygonum hydropiper from China: a comprehensive review on phytochemistry, pharmacological activities and applications | Full Text | References | PDF (2.6 MB) | EPUB
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Article
Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro
Yuan Luo, Zhenyuan Tan, Yun Ye, Xiaocong Ma & Guihua Yue
Pages: 815-824
Published online: 17 May 2023
AbstractforQiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Article
Lantana camara leaf extract ameliorates memory deficit and the neuroinflammation associated with scopolamine-induced Alzheimer’s-like cognitive impairment in zebrafish and mice
Veronica Amoah, Paul Atawuchugi, Yakubu Jibira, Augustine Tandoh, Paul Poku Sampene Ossei, George Sam & George Ainooson
Pages: 825-838
Published online: 22 May 2023
AbstractforLantana camara leaf extract ameliorates memory deficit and the neuroinflammation associated with scopolamine-induced Alzheimer’s-like cognitive impairment in zebrafish and mice | Full Text | References | PDF (3.5 MB) | EPUB
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Article
Identification of natural compound garcinone E as a novel autophagic flux inhibitor with anticancer effect in nasopharyngeal carcinoma cells
Dan Wei, Luolin Wang, Shunmei Lei, Han Zhang, Caihua Dong, Yao Ke, Yuting Su, Xiaoying Chen, Lianping Xia, Xiaoyang Kong, Fuqiang Yin & Xia Liu
Pages: 839-857
Published online: 19 May 2023
AbstractforIdentification of natural compound garcinone E as a novel autophagic flux inhibitor with anticancer effect in nasopharyngeal carcinoma cells | Full Text | References | PDF (7.9 MB) | EPUB
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Article
Gastrodin attenuates angiotensin II-induced vascular contraction and MLCK/p-MLC2 pathway activation
Zhi Guo, Xuan Yang, Meizhu Wu, Aling Shen, Jiapeng Li, Xiuli Zhang, Ying Cheng, Qiurong Xie & Jun Peng
Pages: 858-867
Published online: 21 May 2023
AbstractforGastrodin attenuates angiotensin II-induced vascular contraction and MLCK/p-MLC2 pathway activation | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Article
Sodium tanshinone IIA sulphate inhibits angiogenesis in lung adenocarcinoma via mediation of miR-874/eEF-2K/TG2 axis
Bu Wang, Fang Zou, Gu Xin, Bao-Li Xiang, Jian-Qing Zhao, Sheng-Fang Yuan, Xiu-Long Zhang & Zhi-Hua Zhang
Pages: 868-877
Published online: 09 Jun 2023
AbstractforSodium tanshinone IIA sulphate inhibits angiogenesis in lung adenocarcinoma via mediation of miR-874/eEF-2K/TG2 axis | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis
Xiaoyuan Xu, Xiaohua Xu, Xiaoshuang Wang & Ling Shen
Pages: 878-885
Published online: 05 Jun 2023
AbstractforBaicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis | Full Text | References | PDF (2.4 MB) | EPUB
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Article
Metformin ameliorates ferroptosis in cardiac ischemia and reperfusion by reducing NOX4 expression via promoting AMPKα
Zhenhua Wu, Yunpeng Bai, Yujuan Qi, Chao Chang, Yan Jiao, Yaobang Bai & Zhigang Guo
Pages: 886-896
Published online: 08 Jun 2023
AbstractforMetformin ameliorates ferroptosis in cardiac ischemia and reperfusion by reducing NOX4 expression via promoting AMPKα | Full Text | References | PDF (3.7 MB) | EPUB
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Article
Plantamajoside alleviates acute sepsis-induced organ dysfunction through inhibiting the TRAF6/NF-κB axis
Daili Feng, Ruying Guo, Wei Liao, Jiancheng Li & Song Cao
Pages: 897-906
Published online: 08 Jun 2023
AbstractforPlantamajoside alleviates acute sepsis-induced organ dysfunction through inhibiting the TRAF6/NF-κB axis | Full Text | References | PDF (3.8 MB) | EPUB
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Article
Isoquinoline alkaloids isolated from Glaucium corniculatum var. corniculatum and Glaucium grandiflorum subsp. refractum var. torquatum with bioactivity studies
Tuba Kusman Saygi, Nur Tan, Gülbahar Özge Alim Toraman, Caglayan Unsal Gurer, Osman Tugay & Gulacti Topcu
Pages: 907-917
Published online: 19 Jun 2023
AbstractforIsoquinoline alkaloids isolated from Glaucium corniculatum var. corniculatum and Glaucium grandiflorum subsp. refractum var. torquatum with bioactivity studies | Full Text | References | PDF (3 MB) | EPUB
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Article
Lucialdehyde B suppresses proliferation and induces mitochondria-dependent apoptosis in nasopharyngeal carcinoma CNE2 cells
Lingxue Liu, Zhangning Yu, Jing Chen, Benchen Liu, Changhui Wu, Ye Li, Jianhua Xu & Peng Li
Pages: 918-926
Published online: 15 Jun 2023
AbstractforLucialdehyde B suppresses proliferation and induces mitochondria-dependent apoptosis in nasopharyngeal carcinoma CNE2 cells | Full Text | References | PDF (2.6 MB) | EPUB
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Article
Qingyi granules ameliorate severe acute pancreatitis in rats by modulating the gut microbiota and serum metabolic aberrations
Juying Jiao, Jianjun Liu, Fei Luo, Mengxue Shang, Chen Pan, Bing Qi, Liang Zhao, Peiyuan Yin & Dong Shang
Pages: 927-937
Published online: 15 Jun 2023
AbstractforQingyi granules ameliorate severe acute pancreatitis in rats by modulating the gut microbiota and serum metabolic aberrations | Full Text | References | PDF (3.5 MB) | EPUB
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Article
The kidney antifibrotic effects of 5,7,3′,4′,5′-pentamethoxyflavone from Bauhinia championii in streptozotocin-induced diabetic rats: in vivo and in vitro experiments
Jialin Li, Xiaocui Huang, Kailun He & Suzhen Wu
Pages: 938-948
Published online: 22 Jun 2023
AbstractforThe kidney antifibrotic effects of 5,7,3′,4′,5′-pentamethoxyflavone from Bauhinia championii in streptozotocin-induced diabetic rats: in vivo and in vitro experiments | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Antioxidative effect of Periplaneta americana extract on dextran sulfate sodium-induced ulcerative colitis through activation of the Nrf2 signal
Jianzhong Wu, Zhen Zhang, Qimei Wu, Linli Zhang, Zhipeng Chen, Hairong Zhao, Xiumei Wu, Yu Zhao, Chenggui Zhang, Jian Ge & Heng Liu
Pages: 949-962
Published online: 19 Jun 2023
AbstractforAntioxidative effect of Periplaneta americana extract on dextran sulfate sodium-induced ulcerative colitis through activation of the Nrf2 signal | Full Text | References | PDF (4.7 MB) | EPUB
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Article
Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway
Jian-fei Peng, Xiao-ni Zhao, Meng Zhang, Jing-ya Li, Chun-chun Zhao, Shu-shu Wang, Jia-li Wang, Hui Shi, Peng Zhou & Liang Wang
Pages: 963-972
Published online: 25 Jun 2023
AbstractforPunicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway | Full Text | References | PDF (3.8 MB) | EPUB
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Article
Investigating material basis and molecular mechanism of Qing Cuo formula in the treatment of acne based on animal experiments, UPLC-LTQ-Orbitrap-MS and network pharmacology
Yanqi Cao, Jinfeng Liang, Chunguo Wang, Xuejie Bao, Siqi Li, Qi Liu, Bin Zeng, David Humberto Lopez & Ruoxi Yu
Pages: 973-985
Published online: 30 Jun 2023
AbstractforInvestigating material basis and molecular mechanism of Qing Cuo formula in the treatment of acne based on animal experiments, UPLC-LTQ-Orbitrap-MS and network pharmacology | Full Text | References | PDF (2.6 MB) | EPUB
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Article
The effect of semen cuscutae flavonoid on Sertoli cells and blood-testis barrier in male infertility: integrating network pharmacology and experimental verification
Chen-xiao Liu, Su-qin Hu, Dian-long Liu, Ya-hui Xu, Ke Hu & Jian Guo
Pages: 986-999
Published online: 29 Jun 2023
AbstractforThe effect of semen cuscutae flavonoid on Sertoli cells and blood-testis barrier in male infertility: integrating network pharmacology and experimental verification | Full Text | References | PDF (5.2 MB) | EPUB
  • 1060 Views
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Article
Hyperoside ameliorates cerebral ischaemic–reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway
Lei Shi, Chenchen Jiang, Hanghang Xu, Jiangping Wu, Jiajun Lu, Yuxiang He, Xiuyun Yin, Zhuo Chen, Di Cao, Xuebin Shen, Xuefeng Hou & Jun Han
Pages: 1000-1012
Published online: 06 Jul 2023
AbstractforHyperoside ameliorates cerebral ischaemic–reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway | Full Text | References | PDF (3.8 MB) | EPUB
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Correction

Correction
Correction
Page: 1013
Published online: 13 Jul 2023
CitationforCorrection | Full Text | PDF (142.8 KB) | EPUB
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Research Article

Article
The mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification
Weiguo Liao, Minchun Wang, Ying Wu, Jinyan Du, Yaxin Li, Anyu Su, Lanying Zhong, Zi Xie, Mingyu Gong, Junhui Liang, Pengcheng Wang, Zai Liu & Lisheng Wang
Pages: 1014-1029
Published online: 06 Jul 2023
AbstractforThe mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification | Full Text | References | PDF (5.4 MB) | EPUB
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Article
Characterization of potentially health-promoting constituents in sea fennel (Crithmum maritimum) cultivated in the Conero Natural Park (Marche region, Central Italy)
Antonietta Maoloni, Teresa Pirker, Eva-Maria Pferschy-Wenzig, Lucia Aquilanti & Rudolf Bauer
Pages: 1030-1040
Published online: 06 Jul 2023
AbstractforCharacterization of potentially health-promoting constituents in sea fennel (Crithmum maritimum) cultivated in the Conero Natural Park (Marche region, Central Italy) | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway
Dongli Li, Jianchao Si, Yajing Guo, Bingbing Liu, Xue Chen, Kerong Qi, Shengchang Yang & Ensheng Ji
Pages: 1041-1053
Published online: 10 Jul 2023
AbstractforDanggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway | Full Text | References | PDF (4.1 MB) | EPUB
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Article
Metabolomics reveals the effects of hydroxysafflor yellow A on neurogenesis and axon regeneration after experimental traumatic brain injury
En Hu, Teng Li, Zhilin Li, Hong Su, Qiuju Yan, Lei Wang, Haigang Li, Wei Zhang, Tao Tang & Yang Wang
Pages: 1054-1064
Published online: 07 Jul 2023
AbstractforMetabolomics reveals the effects of hydroxysafflor yellow A on neurogenesis and axon regeneration after experimental traumatic brain injury | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
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Review Article
Prevalence, motivation, and associated factors of medicinal herbs consumption in pregnant women from Eastern Mediterranean Regional Office: a systematic review
Afaf Bouqoufi, Laila Lahlou, Fatima Ait El Hadj, Mohammed Abdessadek, Majdouline Obtel & Youssef Khabbal
Pages: 1065-1081
Published online: 14 Jul 2023
AbstractforPrevalence, motivation, and associated factors of medicinal herbs consumption in pregnant women from Eastern Mediterranean Regional Office: a systematic review | Full Text | References | PDF (1.3 MB) | EPUB
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Transcriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice
Zhe Liu, Jin-ru Zhang, Yong-xiang Huang, Xue-ying Li, Hai-peng Zhu, Rui-yi Yang & Song Chen
Pages: 1082-1093
Published online: 13 Jul 2023
AbstractforTranscriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
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Review Article
Effect-enhancing and toxicity-reducing effects of Chaihu Jia Longgu Muli decoction in the treatment of multimorbidity with depression: a systematic review and meta-analysis
Xurui Jia, Jie Chen, Ruiou Huang, Dawei Wang & Xing Wang
Pages: 1094-1106
Published online: 13 Jul 2023
AbstractforEffect-enhancing and toxicity-reducing effects of Chaihu Jia Longgu Muli decoction in the treatment of multimorbidity with depression: a systematic review and meta-analysis | Full Text | References | PDF (3.9 MB) | EPUB
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Correction

Correction
Correction
Page: 1107
Published online: 14 Jul 2023
CitationforCorrection | Full Text | PDF (144.6 KB) | EPUB
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Article
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation
Shuo Zhang, Ya-Ning Shi, Jia Gu, Peng He, Qi-Di Ai, Xu-Dong Zhou, Wei Wang & Li Qin
Pages: 1108-1119
Published online: 18 Jul 2023
AbstractforMechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation | Full Text | References | PDF (5.1 MB) | EPUB | Supplemental
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Article
Identification of Rab7 as an autophagy marker: potential therapeutic approaches and the effect of Qi Teng Xiao Zhuo granule in chronic glomerulonephritis
Xiujuan Qin, Huiyu Chen, Xiaoli Zhu, Xianjin Xu & Jiarong Gao
Pages: 1120-1134
Published online: 21 Jul 2023
AbstractforIdentification of Rab7 as an autophagy marker: potential therapeutic approaches and the effect of Qi Teng Xiao Zhuo granule in chronic glomerulonephritis | Full Text | References | PDF (6.4 MB) | EPUB
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Article
Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the MyD88-dependent TLR4 signaling pathway
Md Mahmudul Hasan, Priya Madhavan, Nur Adelina Ahmad Noruddin, Wai Kwan Lau, Qamar Uddin Ahmed, Aditya Arya & Zainul Amiruddin Zakaria
Pages: 1135-1151
Published online: 27 Jul 2023
AbstractforCardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the MyD88-dependent TLR4 signaling pathway | Full Text | References | PDF (5.4 MB) | EPUB
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Article
Liver protective effect of chloroform extract of Bauhinia purpurea leaves is attributed partly to its antioxidant action and the presence of flavonoids
Zainul Amiruddin Zakaria, Adibah Sahmat, Azfar Hizami Azmi, Amal Syahirah Nur Zainol, Maizatul Hasyima Omar, Tavamani Balan, Arifah Abdul Kadir, Syahriel Abdullah, Roro Azizah & Lilis Sulistyorini
Pages: 1152-1161
Published online: 09 Aug 2023
AbstractforLiver protective effect of chloroform extract of Bauhinia purpurea leaves is attributed partly to its antioxidant action and the presence of flavonoids | Full Text | References | PDF (1.6 MB) | EPUB
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Article
Glucocorticoid receptors involved in ginsenoside compound K ameliorate adjuvant arthritis by inhibiting the glycolysis of fibroblast-like synoviocytes via the NF-κB/HIF-1α pathway
Yating Wang, Xiurong Bao, Hao Xian, Fang Wei, Yining Song, Siyu Zhao, Yujie Zhang, Yumeng Wang & Ying Wang
Pages: 1162-1174
Published online: 09 Aug 2023
AbstractforGlucocorticoid receptors involved in ginsenoside compound K ameliorate adjuvant arthritis by inhibiting the glycolysis of fibroblast-like synoviocytes via the NF-κB/HIF-1α pathway | Full Text | References | PDF (4.5 MB) | EPUB
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Article
Nardostachys jatamansi and levodopa combination alleviates Parkinson’s disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways
Jiayuan Li, Jiahe Yu, Jianyou Guo, Jinfeng Liu, Guohui Wan, Xiaojia Wei, Xue Yang & Jinli Shi
Pages: 1175-1185
Published online: 09 Aug 2023
AbstractforNardostachys jatamansi and levodopa combination alleviates Parkinson’s disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways | Full Text | References | PDF (3.3 MB) | EPUB
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Review Article
Recent advances towards natural plants as potential inhibitors of SARS-Cov-2 targets
Zhouman He, Jia Yuan, Yuanwen Zhang, Runfeng Li, Meilan Mo, Yutao Wang & Huihui Ti
Pages: 1186-1210
Published online: 22 Aug 2023
AbstractforRecent advances towards natural plants as potential inhibitors of SARS-Cov-2 targets | Full Text | References | PDF (3.5 MB) | EPUB
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A standardized extract of Echinacea purpurea containing higher chicoric acid content enhances immune function in murine macrophages and cyclophosphamide-induced immunosuppression mice
Heggar Venkataramana Sudeep, Kuluvar Gouthamchandra, Illuri Ramanaiah, Amritha Raj, Puttaswamy Naveen & Kodimule Shyamprasad
Pages: 1211-1221
Published online: 10 Aug 2023
AbstractforA standardized extract of Echinacea purpurea containing higher chicoric acid content enhances immune function in murine macrophages and cyclophosphamide-induced immunosuppression mice | Full Text | References | PDF (2.6 MB) | EPUB
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Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy
Borui Yu, Mengqi Zhou, Zhaocheng Dong, Huijuan Zheng, Yuxue Zhao, Jingwei Zhou, Chao Zhang, Fudong Wei, Guoyong Yu, Wei Jing Liu, Hongfang Liu & Yaoxian Wang
Pages: 1222-1233
Published online: 11 Aug 2023
AbstractforIntegrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy | Full Text | References | PDF (4.4 MB) | EPUB
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Article
Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways
Ting Chen, Shengchuan Bao, Juan Chen, Jiaxiang Zhang, Hailiang Wei, Xin Hu, Yan Liang, Jingtao Li & Shuguang Yan
Pages: 1234-1248
Published online: 21 Aug 2023
AbstractforXiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways | Full Text | References | PDF (5 MB) | EPUB
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Article
Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis
Wei Zhao, Huan-Huan Yu, Wei-Wei Meng, Ai-Min Liu, Bu-Xin Zhang, Ying Wang, Jie Li, Li Wang & Yu-Fu Fang
Pages: 1249-1259
Published online: 21 Aug 2023
AbstractforIcariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis | Full Text | References | PDF (2.7 MB) | EPUB
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Article
Mechanistic exploration of Yiqi Liangxue Shengji prescription on restenosis after balloon injury by integrating metabolomics with network pharmacology
Tianshi Mao, Long Xie, Yanqiong Guo, Xiang Ji, Jie Wan, Xiaoyun Cui, Qian Fan, Wei Liu, Shuai Wang, Wenbo Han, Qian Lin & Wenhao Jia
Pages: 1260-1273
Published online: 21 Aug 2023
AbstractforMechanistic exploration of Yiqi Liangxue Shengji prescription on restenosis after balloon injury by integrating metabolomics with network pharmacology | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
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Article
Clerodendranthus spicatus inhibits epithelial–mesenchymal transition of renal tubular cells through the NF-κB/Snail signalling pathway in hyperuricaemia nephropathy
Shouhai Wu, Meixia Yan, Junyi Liu, Yizhen Li, Ruimin Tian, Chuang Li, Lihuang Huang, Zhisheng Lu, Peng Xu & Wei Mao
Pages: 1274-1285
Published online: 21 Aug 2023
AbstractforClerodendranthus spicatus inhibits epithelial–mesenchymal transition of renal tubular cells through the NF-κB/Snail signalling pathway in hyperuricaemia nephropathy | Full Text | References | PDF (4.9 MB) | EPUB
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Article
Exploring the mechanisms of action of Zengye decoction (ZYD) against Sjogren’s syndrome (SS) using network pharmacology and animal experiment
Jiake Yu, Shuying Wang, Jie Yang, Wuxinrui Huang, Beikang Tang, Weijun Peng & Jing Tian
Pages: 1286-1297
Published online: 22 Aug 2023
AbstractforExploring the mechanisms of action of Zengye decoction (ZYD) against Sjogren’s syndrome (SS) using network pharmacology and animal experiment | Full Text | References | PDF (2.7 MB) | EPUB
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Article
Gemcitabine enhances pharmacokinetic exposure of the major components of Danggui Buxue Decoction in rat via the promotion of intestinal permeability and down-regulation of CYP3A for combination treatment of non-small cell lung cancer
Xin Xu, Xi-yang Sun, Ming Chang, Zhao-liang Hu, Ting-ting Cheng, Tai-jun Hang & Min Song
Pages: 1298-1309
Published online: 22 Aug 2023
AbstractforGemcitabine enhances pharmacokinetic exposure of the major components of Danggui Buxue Decoction in rat via the promotion of intestinal permeability and down-regulation of CYP3A for combination treatment of non-small cell lung cancer | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
Jiacheng Gao, Yuhang Wang, Zirui Jia, Jiaming Xue, Tingting Zhou & Guo Zu
Pages: 1310-1317
Published online: 24 Aug 2023
Abstractfor(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1 | Full Text | References | PDF (2.2 MB) | EPUB
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Article
Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
Fei Mu, Rui Lin, Xueyan Lu, Meina Zhao, Jiaxin Zhao, Shaojie Huang, Chao Guo, Yue Guan, Haiyue Zhang, Miaomiao Xi, Jingwen Wang & Haifeng Tang
Pages: 1318-1331
Published online: 24 Aug 2023
AbstractforProtective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis | Full Text | References | PDF (3.4 MB) | EPUB
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Article
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway
Jiani Liu, Li Li, Xue Han, Yue Chen & Juanjuan Diao
Pages: 1332-1342
Published online: 01 Sep 2023
AbstractforLoke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway | Full Text | References | PDF (2.8 MB) | EPUB
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Article
Tormentic acid, a triterpenoid isolated from the fruits of Chaenomeles speciose, protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway
Jun-Yu He, Jie Li, Yuan-Yuan Zhang, Hai-Bo He, Yu-Min He, Dao-Xiang Xu, Xiao Wang, Hao-Yang Wu, Ji-Hong Zhang, Hasan Jahid, Akter Sadia, Hui-Fan Yu, Jun-Zhi Wang & Kun Zou
Pages: 1343-1363
Published online: 25 Aug 2023
AbstractforTormentic acid, a triterpenoid isolated from the fruits of Chaenomeles speciose, protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway | Full Text | References | PDF (5.8 MB) | EPUB
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Article
Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/β-catenin signalling pathway
Zhongwen Qi, Zhipeng Yan, Ke Zhu, Yueyao Wang, Yajie Fan, Tingting Li & Junping Zhang
Pages: 1364-1373
Published online: 31 Aug 2023
AbstractforNovel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/β-catenin signalling pathway | Full Text | References | PDF (2.1 MB) | EPUB
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Article
Optimization of the proportions of advantageous components in the hypolipidemic “bioequivalent substance system” of Jiang-Zhi-Ning and its mechanism of action
Yumiao Li, Yan Zhang, Yu Zhang, Tianfeng Lin, Yanyan Gao, Yuan Cai, Chang Zhou, Leyi Yang, Bin Liu, Shifen Dong & Yanyan Jiang
Pages: 1374-1386
Published online: 01 Sep 2023
AbstractforOptimization of the proportions of advantageous components in the hypolipidemic “bioequivalent substance system” of Jiang-Zhi-Ning and its mechanism of action | Full Text | References | PDF (2.6 MB) | EPUB
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Article
Bu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway
Hui Zhang, Huihua Wang, Qing Zhang, Hui Wang, Yuhang Zhu, Fangfang Wang, Jun Lin, Jue Zhou & Fan Qu
Pages: 1387-1400
Published online: 01 Sep 2023
AbstractforBu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway | Full Text | References | PDF (2.8 MB) | EPUB
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Article
Saponins from Panax japonicus improve neuronal mitochondrial injury of aging rats
Cheng Fan, Jin-Xin Wang, Zhang-E. Xiong, Shan-Shan Hu, Ao-Jia Zhou, Ding Yuan, Chang-Cheng Zhang, Zhi-Yong Zhou & Ting Wang
Pages: 1401-1412
Published online: 04 Sep 2023
AbstractforSaponins from Panax japonicus improve neuronal mitochondrial injury of aging rats | Full Text | References | PDF (3.8 MB) | EPUB
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Correction

Correction
Correction
Page: 1413
Published online: 04 Sep 2023
CitationforCorrection | Full Text | PDF (145.3 KB) | EPUB
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Integrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced depression
Yan Luo, Ziyan Zhong, Huan Li, Le Wang, Dongwei Guo, Xuanqi Dong, Jian Liu, Mingxia Xie, Mei Wu, Yun Xiang, Xi Zhang & Pan Meng
Pages: 1414-1430
Published online: 09 Sep 2023
AbstractforIntegrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced depression | Full Text | References | PDF (4.8 MB) | EPUB
  • 1513 Views
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Article
Mechanism investigation of Duhuo Jisheng pill against rheumatoid arthritis based on a strategy for the integration of network pharmacology, molecular docking and in vivo experimental verification
Ping Xin, Xiaoyun Xu, Huaxi Zhang, Yuezhou Hu, Chengjie Deng, Shiqin Sun, Shuang Liu, Xuegang Zhou, Hongxing Ma & Xiaoliang Li
Pages: 1431-1445
Published online: 06 Sep 2023
AbstractforMechanism investigation of Duhuo Jisheng pill against rheumatoid arthritis based on a strategy for the integration of network pharmacology, molecular docking and in vivo experimental verification | Full Text | References | PDF (4.1 MB) | EPUB
  • 1254 Views
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Article
Extracts of Thesium chinense inhibit SARS-CoV-2 and inflammation in vitro
Juncheng Ma, Juanru Wei, Gang Chen, Xiaowei Yan, Hechun Sun & Ning Li
Pages: 1446-1453
Published online: 07 Sep 2023
AbstractforExtracts of Thesium chinense inhibit SARS-CoV-2 and inflammation in vitro | Full Text | References | PDF (1.1 MB) | EPUB
  • 959 Views
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Article
Paeoniflorin suppresses the apoptosis and inflammation of human coronary artery endothelial cells induced by oxidized low-density lipoprotein by regulating the Wnt/β-catenin pathway
Shasha Liu, Ying Li & Caojie Wu
Pages: 1454-1461
Published online: 06 Sep 2023
AbstractforPaeoniflorin suppresses the apoptosis and inflammation of human coronary artery endothelial cells induced by oxidized low-density lipoprotein by regulating the Wnt/β-catenin pathway | Full Text | References | PDF (1.8 MB) | EPUB
  • 1178 Views
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Article
Evaluation of topical methylene blue nanoemulsion for wound healing in diabetic mice
Yu Gao, Zhounan Jiang, Bin Xu, Ran Mo, Shiyan Li, Yanan Jiang, Demei Zhao, Wangbin Cao, Bin Chen, Meng Tian & Qian Tan
Pages: 1462-1473
Published online: 10 Sep 2023
AbstractforEvaluation of topical methylene blue nanoemulsion for wound healing in diabetic mice | Full Text | References | PDF (2.7 MB) | EPUB
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Review Article

Review Article
Efficacy and safety of berberine for premature ventricular contractions: a meta-analysis and systematic review of randomized controlled trials
Meng Qiao, Chao Lei, Chaoren Tan, Cuncun Lu, Zijia Chen, Qiang Zhang & Zhifei Wang
Pages: 1474-1483
Published online: 19 Oct 2023
AbstractforEfficacy and safety of berberine for premature ventricular contractions: a meta-analysis and systematic review of randomized controlled trials | Full Text | References | PDF (2.6 MB) | EPUB
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Review Article
Chemical profile of the Anatolian Sideritis species with bioactivity studies
Sema Çarıkçı, Turgut Kılıç, Ahmet C. Gören, Tuncay Dirmenci, Gülbahar Özge Alim Toraman & Gülaçtı Topçu
Pages: 1484-1511
Published online: 22 Nov 2023
AbstractforChemical profile of the Anatolian Sideritis species with bioactivity studies | Full Text | References | PDF (4.5 MB) | EPUB
  • 1482 Views
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Article
Network pharmacology integrated with experimental verification reveals the antipyretic characteristics and mechanism of Zi Xue powder
Hanyu Zhang, Shining Ge, Fengyin Diao, Wen Song, Ying Zhang, Pengwei Zhuang & Yanjun Zhang
Pages: 1512-1524
Published online: 09 Dec 2023
AbstractforNetwork pharmacology integrated with experimental verification reveals the antipyretic characteristics and mechanism of Zi Xue powder | Full Text | References | PDF (8.2 MB) | EPUB
  • 702 Views
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Article
Network pharmacology identification and in vivo validation of key pharmacological pathways of Qin Jiao for gout and arthritis
Xiaoxiong Yang, Yu Wang, Xueli Ding, Shanshan Ju, Xiaoye An, Bing Zhang & Zhijian Lin
Pages: 1525-1535
Published online: 09 Dec 2023
AbstractforNetwork pharmacology identification and in vivo validation of key pharmacological pathways of Qin Jiao for gout and arthritis | Full Text | References | PDF (3.9 MB) | EPUB
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